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1.
Sensors (Basel) ; 21(7)2021 Apr 03.
Artigo em Inglês | MEDLINE | ID: mdl-33916649

RESUMO

A common problem in through-wall radar is reflected signals much attenuated by wall and environmental noise. The reflected signal is a convolution product of a wavelet and an unknown object time series. This paper aims to extract the object time series from a noisy receiving signal of through-wall ultrawideband (UWB) radar by sparse deconvolution based on arctangent regularization. Arctangent regularization is one of the suitably nonconvex regularizations that can provide a reliable solution and more accuracy, compared with convex regularizations. An iterative technique for this deconvolution problem is derived by the majorization-minimization (MM) approach so that the problem can be solved efficiently. In the various experiments, sparse deconvolution with the arctangent regularization can identify human positions from the noisy received signals of through- wall UWB radar. Although the proposed method is an odd concept, the interest of this paper is in applying sparse deconvolution, based on arctangent regularization with an S-band UWB radar, to provide a more accurate detection of a human position behind a concrete wall.


Assuntos
Radar , Projetos de Pesquisa , Humanos , Sujeitos da Pesquisa
4.
Trials ; 22(1): 62, 2021 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-33461595

RESUMO

There is a dearth of literature on best practices for managing clinical trials, and little is understood on the role of the clinical trial manager. The COVID-19 pandemic has brought this into focus, and the continuance of clinical trials worldwide has been catapulted into a state of uncertainty as countries enter lockdown to manage the spread of the virus. Participant retention is an ongoing issue in clinical trials, and the concern is that in the current pandemic environment, attrition will be an issue which could potentially jeopardise trial completion. The current situation has necessitated timely problem solving by the trial manager to ensure trials remain open, and most importantly, that participant safety, paramount in clinical trials, is monitored. The purpose of our study is to highlight key issues arising in the management of clinical trials during a pandemic from first-hand experience in a clinical research facility managing both academic and commercial clinical trials. We offer some practical guidance on solution implementation.


Assuntos
Academias e Institutos/organização & administração , Ensaios Clínicos como Assunto/organização & administração , Pessoal Administrativo , Ensaios Clínicos Fase III como Assunto , Controle de Doenças Transmissíveis , Comunicação , Coleta de Dados , Hospitais Universitários , Humanos , Irlanda , Liderança , Pacientes Desistentes do Tratamento , Seleção de Pacientes , Admissão e Escalonamento de Pessoal , Política Pública , Pesquisadores , Sujeitos da Pesquisa
6.
J Mech Behav Biomed Mater ; 116: 104271, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33517100

RESUMO

During an underbody blast (UBB) event, mounted occupants are exposed to high rate loading of the spine via the pelvis. The objective of this study was to simulate UBB loading conditions and examine mechanisms of injury in the thoracic, lumbar and sacral spine. Fourteen instrumented, whole-body, postmortem human subject (PMHS) experiments were performed using the WSU-decelerative horizontal sled system. The specimens were positioned supine on a decelerative sled, which then impacted an energy absorbing system mounted to a concrete barrier. Variables included the peak velocity and time-to-peak velocity for seat and floor, and the presence or absence of personal protective equipment (PPE) and seat padding. Post-test CT scans and autopsies were performed to identify the presence and severity of injuries. Acceleration and angular rate data collected at vertebra T1, T5, T8, T12, and S1 were used to assess injury timing and mechanisms. Additionally, joint time-frequency analysis (JTFA) of the spinal Z acceleration of the sacrum and vertebrae was developed with the aim of verifying spinal fracture timing. Injuries observed in the spine were attributed to axial compression applied through the pelvis, together with flexion moment due to the offset in the center of gravity of the torso, and are consistent with UBB-induced combat injuries reported in the literature. The injury timing estimation techniques discussed in this study provide a time interval when the fractures are predicted to have occurred. Furthermore, this approach serves as an alternative to the estimation methods using acoustic sensors, force and acceleration traces, and strain gauges.


Assuntos
Acidentes de Trânsito , Explosões , Aceleração , Fenômenos Biomecânicos , Cadáver , Humanos , Sujeitos da Pesquisa
8.
Proc Natl Acad Sci U S A ; 118(1)2021 01 05.
Artigo em Inglês | MEDLINE | ID: mdl-33443151

RESUMO

Randomized controlled trials (RCTs) enroll hundreds of millions of subjects and involve many human lives. To improve subjects' welfare, I propose a design of RCTs that I call Experiment-as-Market (EXAM). EXAM produces a welfare-maximizing allocation of treatment-assignment probabilities, is almost incentive-compatible for preference elicitation, and unbiasedly estimates any causal effect estimable with standard RCTs. I quantify these properties by applying EXAM to a water-cleaning experiment in Kenya. In this empirical setting, compared to standard RCTs, EXAM improves subjects' predicted well-being while reaching similar treatment-effect estimates with similar precision.


Assuntos
Experimentação Humana/ética , Ensaios Clínicos Controlados Aleatórios como Assunto/ética , Sujeitos da Pesquisa/psicologia , Causalidade , Humanos , Modelos Teóricos , Ensaios Clínicos Controlados Aleatórios como Assunto/métodos , Projetos de Pesquisa , Sujeitos da Pesquisa/estatística & dados numéricos
9.
J Pediatr Adolesc Gynecol ; 34(2): 190-195, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33333259

RESUMO

STUDY OBJECTIVE: In this study we evaluated published studies about foster care to: (1) determine the types of data used; (2) describe the degree to which a sexual/reproductive health topic was addressed; and (3) describe the consent process. DESIGN: Analysis of published literature. SETTING: PubMed was searched using "foster care" for English articles published between January 1, 2017 and September 4, 2019. PARTICIPANTS: None. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Articles were coded into 4 data source categories: primary, secondary, peripheral, or perspective data. Articles with a primary data source were coded for participant ages: only 9 years old and younger, 10- to 17-year-olds (minor adolescents), and only 18 years old and older. Articles using a secondary data source were coded for the source of the data registry. All articles were coded for presence of a sexual/reproductive health outcome. The primary data articles that included minor adolescents were coded for the study topic and consent process. RESULTS: Of the 176 articles about foster care, 72/176 (41%) used primary data, 53/176 (30%) used secondary data, and 51/176 (29%) used peripheral/perspective data. Forty-eight of the primary data articles included minor adolescents. Secondary data sources included few national research surveys. Sexual/reproductive health outcomes were measured in 17 articles, 4 of which used primary data. The consent process for minor adolescents varied and had no consistent pattern across studies. CONCLUSION: Research on best practices for consent processes and use of registries could be developed to increase research on sexual/reproductive health outcomes among adolescents in foster care.


Assuntos
Criança Acolhida/estatística & dados numéricos , Consentimento Informado por Menores/estatística & dados numéricos , Saúde Reprodutiva , Sujeitos da Pesquisa/estatística & dados numéricos , Saúde Sexual , Adolescente , Criança , Feminino , Humanos , Masculino
10.
Farm. hosp ; 44(6): 254-271, nov.-dic. 2020. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-197694

RESUMO

OBJETIVO: Desarrollar un cuestionario en español dirigido a evaluar el proceso de información y obtención del consentimiento informado en investigación clínica desde la perspectiva del paciente. Con esta herramienta se pretende analizar en los pacientes que participan en un ensayo clínico los siguientes aspectos: la experiencia y desarrollo práctico del proceso de consentimiento informado, su nivel de satisfacción con dicho proceso y su nivel de comprensión del estudio. MÉTODO: Estudio de desarrollo, adaptación y validación de un cuestionario autocumplimentable para evaluar el proceso de consentimiento informado a través de la información obtenida de los pacientes. Los pasos seguidos fueron: revisión bibliográfica, generación de un pool de ítems, redacción del cuestionario, revisión por expertos, pilotaje, optimización y análisis de legibilidad. También se realizó una evaluación, selección, traducción y adaptación al español de una herramienta disponible en lengua inglesa que permitiese valorar la comprensión del paciente de la información. RESULTADOS: El cuestionario quedó conformado por cuatro apartados que permiten evaluar: 1) datos sociodemográficos, 2) aspectos prácticos relacionados con el desarrollo del proceso de consentimiento informado, 3) valoración del paciente del proceso (satisfacción, expectativas y motivaciones), 4) grado de comprensión. Para valorar la comprensión se seleccionó el cuestionario Quality of Informed Consent questionnaire, que fue traducido por tres traductores bilingües. Se incluyeron tres preguntas adicionales para evaluar la comprensión de conceptos relacionados con el equívoco terapéutico y el enmascaramiento de los tratamientos. La validez de contenido fue evaluada mediante consulta con un panel de expertos. En el análisis de legibilidad se obtuvo un valor de Índice de Flesch-Szigriszt de 64,34 equivalente a un grado de dificultad "normal" en la escala Inflesz. En el estudio piloto se entrevistó a 32 pacientes que mostraron no tener dificultades para comprender las preguntas ni problemas a la hora de utilizar las escalas de respuesta. El tiempo medio de cumplimentación del cuestionario fue de 16,6 minutos. CONCLUSIONES: La herramienta desarrollada es útil a la hora de conocer y valorar el proceso de consentimiento informado desde la perspectiva del paciente al que se le invita a participar en un estudio. Su aplicación podría resultar de ayuda a los investigadores para verificar que se ha seguido un adecuado proceso y para identificar aspectos concretos que son susceptibles de ser modificados y optimizados


OBJECTIVE: To develop a Spanish-language questionnaire aimed at evaluating patients' perception of the way they are briefed and their consent is obtained prior to participating in clinical trials. The tool was conceived to evaluate the following aspects: patients' personal experience, the way the informed consent process was implemented in practice, patients' level of satisfaction with the process, and their level of understanding of the study itself. METHOD: This study looked into the development, adaptation and validation of a self-administered questionnaire intended to evaluate the informed consent process on the basis of information provided by respondents. The steps followed included: literature review, generation of an items pool, drawing up of the questionnaire, expert review, piloting, and reading ease optimization and analysis. A commonly-used English-language questionnaire was evaluated, translated into Spanish and adapted so as to determine the extent to which subjects understood the information conveyed to them. RESULTS: In its final version, the questionnaire came to comprise four sections intended to evaluate: 1) socio-demographic data; 2) practical aspects related with the development of the informed consent process; 3) patients' perception of the process (satisfaction, expectations and motivations); and 4) their level of understanding. Understanding was gaged using the QuIC questionnaire, translated by three bilingual translators. Additional questions were included to evaluate the understanding of concepts related with blinding and therapeutic misconception. The validity of the contents was evaluated by consulting with an expert panel. The reading ease analysis yielded an IFSZ score of 64.34, equivalent to an "average difficulty" grade on the Inflesz scale. In the pilot study, interviews were held with 32 patients, who did not appear to have any difficulties in understanding the questions asked of them or in using Likert-type scales to respond. Mean completion time was 16.6 minutes. CONCLUSIONS: The tool developed as part of this study has shown itself capable of providing an understanding and an assessment of the informed consent process from the perspective of a patient who is invited to participate in a clinical trial. Implementation of the questionnaire could help investigators ascertain that the process has been correctly executed and identify specific aspects that may require to be changed or optimized


Assuntos
Humanos , Ensaios Clínicos como Assunto/normas , Consentimento Livre e Esclarecido , Sujeitos da Pesquisa/educação , Educação de Pacientes como Assunto/métodos , Seleção de Pacientes , Satisfação do Paciente , Tomada de Decisões , Projetos Piloto
11.
Bull World Health Organ ; 98(9): 625-631, 2020 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-33012862

RESUMO

While governments have been focusing on the unprecedented disruption to the global economy caused by coronavirus disease 2019 (COVID-19) and the urgent need for COVID-19 research, other health research has become a casualty of the pandemic. Major research operations that are unrelated to COVID-19 have been significantly diminished or suspended entirely because of either COVID-19-related legal restrictions or logistical, staffing or operational concerns. Billions of people globally are currently affected by lockdowns or curfews. Since the timescale of such restrictive measures is unknown and subject to change, many studies are now in limbo and the welfare of tens of thousands of study participants is at risk. These circumstances have introduced complex ethical challenges that merit urgent attention from international sponsors, researchers and regulators. Certain sponsors and regulators have published guidelines on how the COVID-19-related disruptions to clinical research should be managed. Although these guidelines provide a good starting point in navigating the challenges of the evolving pandemic, they only apply to those researchers funded or governed by these bodies. Here, we provide guidelines on managing such disruptions that apply beyond these specific settings. We highlight some of the effects of the COVID-19 pandemic on other ongoing research projects that are unrelated to COVID-19 and provide practical guidance on how the welfare of affected study participants should be managed. We conclude that policy-makers, sponsors, researchers and regulators must adopt a more flexible approach to ensure participant safety, while maintaining data integrity and complying with good clinical practices.


Assuntos
Pesquisa Biomédica/economia , Pesquisa Biomédica/legislação & jurisprudência , Infecções por Coronavirus/epidemiologia , Pneumonia Viral/epidemiologia , Betacoronavirus , Humanos , Pandemias , Pesquisadores , Sujeitos da Pesquisa
12.
Cochrane Database Syst Rev ; 10: MR000045, 2020 Oct 07.
Artigo em Inglês | MEDLINE | ID: mdl-33026107

RESUMO

BACKGROUND: Randomised trials (also referred to as 'randomised controlled trials' or 'trials') are the optimal way to minimise bias in evaluating the effects of competing treatments, therapies and innovations in health care. It is important to achieve the required sample size for a trial, otherwise trialists may not be able to draw conclusive results leading to research waste and raising ethical questions about trial participation. The reasons why potential participants may accept or decline participation are multifaceted. Yet, the evidence of effectiveness of interventions to improve recruitment to trials is not substantial and fails to recognise these individual decision-making processes. It is important to synthesise the experiences and perceptions of those invited to participate in randomised trials to better inform recruitment strategies. OBJECTIVES: To explore potential trial participants' views and experiences of the recruitment process for participation. The specific objectives are to describe potential participants' perceptions and experiences of accepting or declining to participate in trials, to explore barriers and facilitators to trial participation, and to explore to what extent barriers and facilitators identified are addressed by strategies to improve recruitment evaluated in previous reviews of the effects of interventions including a Cochrane Methodology Review. SEARCH METHODS: We searched the Cochrane Library, Medline, Embase, CINAHL, Epistemonikos, LILACS, PsycINFO, ORRCA, and grey literature sources. We ran the most recent set of searches for which the results were incorporated into the review in July 2017. SELECTION CRITERIA: We included qualitative and mixed-methods studies (with an identifiable qualitative component) that explored potential trial participants' experiences and perceptions of being invited to participate in a trial. We excluded studies that focused only on recruiters' perspectives, and trials solely involving children under 18 years, or adults who were assessed as having impaired mental capacity. DATA COLLECTION AND ANALYSIS: Five review authors independently assessed the titles, abstracts and full texts identified by the search. We used the CART (completeness, accuracy, relevance, timeliness) criteria to exclude studies that had limited focus on the phenomenon of interest. We used QSR NVivo to extract and manage the data. We assessed methodological limitations using the Critical Skills Appraisal Programme (CASP) tool. We used thematic synthesis to analyse and synthesise the evidence. This provided analytical themes and a conceptual model. We used the GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative research) approach to assess our confidence in each finding. Our findings were integrated with two previous intervention effectiveness reviews by juxtaposing the quantitative and qualitative findings in a matrix. MAIN RESULTS: We included 29 studies (published in 30 papers) in our synthesis. Twenty-two key findings were produced under three broad themes (with six subthemes) to capture the experience of being invited to participate in a trial and making the decision whether to participate. Most of these findings had moderate to high confidence. We identified factors from the trial itself that influenced participation. These included how trial information was communicated, and elements of the trial such as the time commitment that might be considered burdensome. The second theme related to personal factors such as how other people can influence the individual's decision; and how a personal understanding of potential harms and benefits could impact on the decision. Finally, the potential benefits of participation were found to be key to the decision to participate, namely personal benefits such as access to new treatments, but also the chance to make a difference and help others. The conceptual model we developed presents the decision-making process as a gauge and the factors that influence whether the person will, or will not, take part. AUTHORS' CONCLUSIONS: This qualitative evidence synthesis has provided comprehensive insight into the complexity of factors that influence a person's decision whether to participate in a trial. We developed key questions that trialists can ask when developing their recruitment strategy. In addition, our conceptual model emphasises the need for participant-centred approaches to recruitment. We demonstrated moderate to high level confidence in our findings, which in some way can be attributed to the large volume of highly relevant studies in this field. We recommend that these insights be used to direct or influence or underpin future recruitment strategies that are developed in a participant-driven way that ultimately improves trial conduct and reduces research waste.


Assuntos
Tomada de Decisões , Seleção de Pacientes , Ensaios Clínicos Controlados Aleatórios como Assunto , Sujeitos da Pesquisa/psicologia , Adulto , Comunicação , Apoio Financeiro , Humanos , Educação de Pacientes como Assunto/métodos , Pesquisa Qualitativa , Distribuição Aleatória , Medição de Risco , Tamanho da Amostra , Recusa do Paciente ao Tratamento/psicologia
14.
Gac. sanit. (Barc., Ed. impr.) ; 34(5): 524-527, sept.-oct. 2020. tab
Artigo em Espanhol | IBECS | ID: ibc-198878

RESUMO

Las sexualidades son un aspecto central de la vida de las personas jóvenes. Es una labor de la salud pública entender cómo se construyen -con toda su diversidad- para dar respuestas satisfactorias en el ámbito de la salud sexual. Las características propias de la investigación cualitativa (flexible, abierta y reflexiva) brindan la oportunidad de diseñar estudios aceptados y adaptados a las realidades juveniles, especialmente en un campo sensible. Esta nota tiene como objetivo aportar claves para la captación de jóvenes. En nuestro caso, resultó imprescindible el conocimiento de informantes clave respecto a la población de estudio y el contexto de la investigación, tanto para elegir una estrategia de acercamiento y captación como para adecuar las técnicas de recogida de datos. Finalmente, se emplearon entrevistas individuales y grupos triangulares oportunísticamente en salas de espera de servicios de atención a la salud sexual especializados en jóvenes, donde ya había una predisposición a hablar de sexualidad


Sexuality is a central aspect of young's lives. It is a task of public health to understand how they are constructed with all their diversity, and to give satisfactory answers in the field of sexual health. The characteristics of qualitative research (flexible, open and reflective) provide the opportunity to design studies that are accepted and adapted to the realities of young people, especially in a sensitive field. The aim of this note is to provide clues for the recruitment of young people. In our case, the knowledge of key informants regarding the study population and the research context was essential, both to choose an approach and recruitment strategy and to adapt the data collection techniques. Finally, we used individual interviews and triangular groups opportunistically in waiting rooms of sexual health care services specialized in young people, where there was already a predisposition to talk about sexuality


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Sexualidade/psicologia , Comportamento Sexual/psicologia , Saúde Sexual/classificação , Seleção de Pacientes , Sujeitos da Pesquisa/psicologia , Desenvolvimento Psicossexual/classificação , Grupos Focais/métodos , Tamanho da Amostra , 25783 , Serviços de Saúde Reprodutiva/estatística & dados numéricos
15.
Cuad Bioet ; 31(102): 167-182, 2020.
Artigo em Espanhol | MEDLINE | ID: mdl-32910670

RESUMO

In this paper present, from a bioethical perspective, a reflection on how to reconcile efforts to combat the COVID-19 pandemic with the safeguard of human rights. To do this, I develop three points. First, the regulatory framework that justifies the restriction or suspension of rights in the face of serious threats to public health. Second, the declarations of the international bioethics committees on the way in which human rights should be protected during public health crisis. And third, a review of the main rights threatened both by the public health crisis and by the means adopted to combat it. Before going into each of these points, I offer a preliminary note to clarify certain legal concepts and underline the need to overcome disjunctive approaches in considering human rights.


Assuntos
Betacoronavirus , Controle de Doenças Transmissíveis/legislação & jurisprudência , Direitos Humanos/ética , Pandemias/prevenção & controle , Saúde Pública/ética , Controle de Doenças Transmissíveis/métodos , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/prevenção & controle , Comissão de Ética , União Europeia , Liberdade , Recursos em Saúde/ética , Recursos em Saúde/provisão & distribução , Acesso aos Serviços de Saúde/ética , Direitos Humanos/legislação & jurisprudência , Humanos , Pandemias/ética , Pandemias/legislação & jurisprudência , Direitos do Paciente/ética , Direitos do Paciente/legislação & jurisprudência , Autonomia Pessoal , Pneumonia Viral/epidemiologia , Pneumonia Viral/prevenção & controle , Guias de Prática Clínica como Assunto , Saúde Pública/legislação & jurisprudência , Quarentena/ética , Quarentena/legislação & jurisprudência , Sujeitos da Pesquisa , Alocação de Recursos/ética , Espanha , UNESCO
16.
Psychiatr Danub ; 32(Suppl 1): 53-57, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32890363

RESUMO

BACKGROUND: Seafarers are usually exposed to many stressors that are related to different duties on board. Several notable researchers have argued that stress is a transactional phenomenon between the individual and the environment that is largely dependent on the meaning given to the stimulus by the perceiver. One of the many causes of stress are poor communication skills. SUBJECTS AND METHODS: The aim of the study was to xplain why respondents drop out of research. The project was originally supposed to take place over a period of two years and involve a minimum of 30 respondents per group (30 skippers and 30 seafarers) who would take part in the research for at least four weeks while on board, or during the skipper season. Activity was to be measured with the Polar A370 fitness tracker, worn as a wrist-watch or bracelet and used for 24-hour heart rate, bodily activity and sleep pattern tracking for every respondent. The other device used is TANITA MC780MA, which is a segmental body composition analyser. RESULTS: We contacted overall 146 seafarers, of whom: 40 (27.4%) skippers, 43 (29.5%) deck officers and 63 (43.1%) engine officers. Participation was refused by 18 (12.3% of all contacted) individuals and 108 (74.0%) respondents dropped out during the research. Due to group dispersal and a low number of respondents who reached the end of the research, the project will have to be prolonged. CONCLUSION: We believe that the reasons behind respondent dispersal can be found in their inability to recognize the state they are in and in poor communication skills, while at the same time being exposed to extreme and possibly precarious work conditions. This forms a closed loop that only continues to generate even higher stress levels. Further research is needed to look into this phenomenon.


Assuntos
Ocupações , Pacientes Desistentes do Tratamento , Estresse Psicológico , Frequência Cardíaca , Humanos , Sujeitos da Pesquisa , Navios
18.
PLoS One ; 15(8): e0236675, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32790704

RESUMO

BACKGROUND: In most emergency situations or severe illness, patients are unable to consent for clinical trial enrollment. In such circumstances, the decision about whether to participate in a scientific study or not is made by a legally designated representative. OBJECTIVE: To address the willingness of patients admitted to the intensive care unit (ICU) to be enrolled in a scientific study as volunteers, and to assess the agreement between patients' and their legal representatives' opinion concerning enrollment in a scientific study. METHODS: This survey was conducted in two hospitals in São Paulo, Brazil. Patients (≥18 years) with preserved cognitive functions accompanied by a surrogate admitted to the ICU were eligible for this study. A survey containing 28 questions for patients and 8 questions for surrogates was applied within the first 48h from ICU admission. The survey for patients comprised three sections: demographic characteristics, opinion about participation in clinical research and knowledge about the importance of research. The survey for legal representatives contained two sections: demographic characteristics and assessment of legal representatives' opinion in authorizing patients to be enrolled in research. RESULTS: Between January 2017 and May 2018, 208 pairs of ICU patients and their respective legal representatives answered the survey. Out of 208 ICU patients answering the survey, 73.6% (153/208) were willing to be enrolled in the study as volunteers. Of those patients, 65.1% (97/149) would continue participating in a research even if their legal representative did not support their enrollment. Agreement between patients' and surrogates' opinion concerning participation was poor [Kappa = 0.11 (IC95% -0.02 to 0.25)]. If a consent for study participation had been obtained, 69.1% (103/149) of patients would continue participating in the study until its conclusion, and 23.5% (35/149) would allow researchers to use data collected to date, but would withdraw from the study on that occasion. CONCLUSION: The majority of patients admitted to the ICU were willing to be enrolled in a scientific study as volunteers, also after a deferred informed consent procedure has been used. Nevertheless, contradictory opinions between patients and their and their legal representatives' concerning enrollment in a scientific study were often observed.


Assuntos
Consentimento Livre e Esclarecido , Sujeitos da Pesquisa , Adulto , Idoso , Idoso de 80 Anos ou mais , Atitude , Pesquisa Biomédica , Brasil , Cuidados Críticos , Feminino , Humanos , Unidades de Terapia Intensiva , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Inquéritos e Questionários
20.
J Orthop Sports Phys Ther ; 50(8): 413-414, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32736501

RESUMO

This editorial builds on the previous editorials in the patient partnership series, and aims to share practical advice related to compensation for patient research partners. In the authors' first publication on patient partner compensation in research and health care, they presented the "why" and "how." Here, they build on the "how" to help alleviate the awkwardness of that conversation. The compensation conversation, as a regular part of this type of partnership, allows teams to codevelop projects and focus on the output and outcomes of their collaborative work. J Orthop Sports Phys Ther 2020;50(8):413-414. doi:10.2519/jospt.2020.0106.


Assuntos
Pesquisa Biomédica/economia , Compensação e Reparação , Pesquisa sobre Serviços de Saúde/economia , Participação do Paciente/economia , Sujeitos da Pesquisa , Orçamentos , Humanos
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