Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 1.010
Filtrar
2.
Rev Saude Publica ; 53: 111, 2019.
Artigo em Inglês, Português | MEDLINE | ID: mdl-31800908

RESUMO

OBJECTIVE: To describe the four types of horizon scanning (HS) outputs developed by the National Committee for Health Technology Incorporation (CONITEC) and show their main repercussions on the decision-making processes of the Brazilian Ministry of Health (MH). METHODS: Descriptive study based on participant observation and document analysis of HS outputs (internal reports, alert reports, briefs and sections for CONITEC recommendation reports) developed between January 2014 and July 2018. RESULTS: Fifteen internal reports, six alert reports, two briefs and 57 HS sections were produced. Each output has a specific structure according to its purpose. The methodological approach adopted for developing HS outputs in Brazil is described by EuroScan International Network. The outputs had institutional and international repercussions. The activities resulted in the inclusion of HS as a tool for reducing health lawsuits in the legal framework of the MH. One of the internal reports on a high-cost drug not approved in Brazil for a rare disease was requested by the Health Technology Assessments Network for the Americas (RedETSA), showing the international relevance of the outputs. The HS sections in recommendation reports influenced discussions about incorporating technologies into the Unified Health System. CONCLUSIONS: The developed outputs have purposes ranging from helping build arguments for defense of the MH in cases of health judicialization to inform decision-making processes. In addition, HS sections in recommendation reports have grown in importance recently. CONITEC's HS system has been structured, and its role as a tool to inform health managers has shown to be been relevant.


Assuntos
Tecnologia Biomédica/tendências , Tomada de Decisões , Avaliação da Tecnologia Biomédica/tendências , Brasil , Sistemas de Informação em Saúde/tendências , Humanos , Relatório de Pesquisa , Fatores de Tempo
4.
Adv Exp Med Biol ; 1174: 223-263, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31713201

RESUMO

Nanofibrillar forms of amyloidogenic proteins were initially discovered in the context of protein misfolding and disease but have more recently been found at the origin of key biological functionality in many naturally occurring functional materials, such as adhesives and biofilm coatings. Their physiological roles in nature reflect their great strength and stability, which has led to the exploration of their use as the basis of artificial protein-based functional materials. Particularly for biomedical applications, they represent attractive building blocks for the development of, for instance, drug carrier agents due to their inherent biocompatibility and biodegradability. Furthermore, the propensity of proteins to self-assemble into amyloid fibrils can be exploited under microconfinement, afforded by droplet microfluidic techniques. This approach allows the generation of multi-scale functional microgels that can host biological additives and can be designed to incorporate additional functionality, such as to aid targeted drug delivery.


Assuntos
Proteínas Amiloidogênicas , Géis , Proteínas Amiloidogênicas/química , Proteínas Amiloidogênicas/metabolismo , Tecnologia Biomédica/tendências , Géis/química , Microfluídica
5.
Adv Exp Med Biol ; 1174: 291-312, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31713203

RESUMO

Fe3O4, also called magnetite, is a naturally occurring mineral and has been widely used in biomedical applications. However, in the past, all the applications were based on its excellent magnetic properties and neglected its catalytic properties. In 2007, we found that Fe3O4 nanoparticles are able to perform intrinsic enzyme-like activities. A specific term, "nanozyme", is used to describe the new property of intrinsic enzymatic activity of nanomaterials. Since then, Fe3O4 nanoparticles have been used as enzyme mimics, which broadens their applications beyond simply their magnetic properties, with applications in biomedical diagnosis and therapy, environmental monitoring and treatment, the food industry and chemical synthesis. In this chapter, we will summarize the basic features of Fe3O4 as an enzyme mimetic and its applications in biomedicine.


Assuntos
Biomimética , Nanopartículas de Magnetita , Tecnologia Biomédica/tendências , Catálise , Enzimas/metabolismo , Nanopartículas de Magnetita/química
8.
Evid. actual. práct. ambul ; 22(2): e001058, sept. 2019.
Artigo em Espanhol | LILACS | ID: biblio-1046664

RESUMO

El autor desarrolla y reflexiona sobre el uso de Internet como fuente de información médica, analizando los beneficios y potenciales perjuicios de este nuevo escenario de práctica médica al que nos enfrentamos los profesionales de la salud. (AU)


The author develops and reflects on the use of the Internet as a source of medical information, analyzing the benefits and potential harms of this new setting of medical practice that we face as health professionals. (AU)


Assuntos
Humanos , Tecnologia da Informação/tendências , /tendências , Medicina/tendências , Relações Médico-Paciente , Tecnologia Biomédica/tendências
9.
R I Med J (2013) ; 102(6): 15-18, 2019 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-31398962

RESUMO

Since the early 2000s, three-dimensional (3D) printing has become a well-rounded, evolving technology which has begun to revolutionize healthcare. 3D printing enables rapid creation and manufacture of individual patient models from original designs or medical imaging data. These models can be used for surgical planning, procedural training for residents and medical students, and the design and manufacture of surgical instruments, implants and prostheses. Current availability of this advanced technology at the Lifespan 3D Printing Lab permits Rhode Island physicians to utilize 3D printing in multiple, diverse settings to help improve their medical practice and optimize healthcare outcomes. This article describes three case-based examples to demonstrate varies used of 3D printing in Medicine.


Assuntos
Tecnologia Biomédica/tendências , Impressão Tridimensional , Difusão de Inovações , Educação Médica , Humanos , Modelos Anatômicos , Planejamento de Assistência ao Paciente , Próteses e Implantes , Rhode Island , Cirurgia Assistida por Computador
11.
World J Gastroenterol ; 25(27): 3538-3545, 2019 Jul 21.
Artigo em Inglês | MEDLINE | ID: mdl-31367155

RESUMO

The advent of video capsule endoscopy into clinical routine more than 15 years ago led to a substantial change in the diagnostic approach to patients with suspected small bowel diseases, often indicating a deep enteroscopy procedure for diagnostical confirmation or endoscopic treatment. Device assisted enteroscopy was developed in 2001 and for the first time established a practicable, safe and effective method for evaluation of the small bowel. Currently with double-balloon enteroscopy, single-balloon enteroscopy and spiral enteroscopy three different platforms are available in clinical routine. Summarizing, double-balloon enteroscopy seems to offer the deepest insertion depth to the small bowel going hand in hand with the disadvantage of a longer procedural duration. Manual spiral enteroscopy seems to be a faster procedure but without reaching the depth of the DBE in currently available data. Finally, single-balloon enteroscopy seems to be the least complicated procedure to perform. Despite substantial improvements in the field of direct enteroscopy, even nowadays deep endoscopic access to the small bowel with all available methods is still a complex procedure, cumbersome and time-consuming and requires high endoscopic skills. This review will give an overview of the currently available techniques and will further discuss the role of the upcoming new technology of the motorized spiral enteroscopy (PowerSpiral).


Assuntos
Enteroscopia de Balão/instrumentação , Endoscopia por Cápsula/instrumentação , Endoscópios Gastrointestinais , Enteropatias/diagnóstico por imagem , Enteroscopia de Balão/efeitos adversos , Enteroscopia de Balão/métodos , Tecnologia Biomédica/tendências , Endoscopia por Cápsula/efeitos adversos , Endoscopia por Cápsula/métodos , Humanos , Enteropatias/cirurgia , Intestino Delgado/diagnóstico por imagem , Intestino Delgado/cirurgia , Invenções/tendências
13.
G Ital Med Lav Ergon ; 41(2): 121-124, 2019 05.
Artigo em Italiano | MEDLINE | ID: mdl-31170341

RESUMO

SUMMARY: Rehabilitation Specialized Medicine offers new developments in relation to the new technologies, new demography, life expectation and chronicity. The same attention that in modern health systems is given to quality process and outcome, should also concern the hospital structural aspects, in order to humanize these spaces. In this perspective, the definition of a structure easy to access with well-defined areas within it, such us an external waiting area, reception area and work area, represents an integration which allows to achieve the goal of providing quality performance. The need of a new concept of rehabilitation space in the cardio-respiratory area, especially that of the Gymnasium, must be developed keeping in consideration the main scientific guidelines in cardio-respiratory field. Consequently, this will have four dedicated areas respectively to evaluation, aerobic training, strength training and educational, each one characterized by different colors. The abstract idea of "digital comprehensive rehabilitation", in which are inserted all rehabilitative services facilitated by the gym digitalization, are located in this context, and their main aim is to answer to the patient needs.


Assuntos
Reabilitação Cardíaca/métodos , Reabilitação/organização & administração , Doenças Respiratórias/reabilitação , Tecnologia Biomédica/tendências , Unidades Hospitalares , Humanos
14.
G Ital Med Lav Ergon ; 41(2): 125-131, 2019 05.
Artigo em Italiano | MEDLINE | ID: mdl-31170342

RESUMO

SUMMARY: The digitization of processes has become a necessity to make health management remain sustainable. Current organizational models do not enable the increasing efficiency in process governance required by the increasing demand for rehabilitation services. Vice versa, new technologies have an innovative potential for compensation of disability and for operations management. This is context in which the concept of a "comprehensive digital rehabilitation" also said "digital gym" is developed: as a governance system for the whole inpatient rehabilitation path. The author describes the fundamentals of the Maugeri clinical model for a "Digital Gym" and examines some methodological, clinical and organizational issue concerning: information technology, machine operation protocols, clinical evaluation, machine operator interaction, patient doctor interaction, personalization of care, operational changes linked to the electronic workschedule, and the important training needs.


Assuntos
Tecnologia Biomédica/tendências , Modelos Organizacionais , Doenças do Sistema Nervoso/reabilitação , Reabilitação Neurológica/organização & administração , Pessoas com Deficiência , Humanos , Doença dos Neurônios Motores/reabilitação
15.
Wiad Lek ; 72(6): 1178-1182, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31175724

RESUMO

OBJECTIVE: Introduction: Technology developed specifically for patients progresses quickly and helps patients in hospital as well as at home. It helps the healthy population to stay healthy. Technology can broadly be divided into hardware and software. PATIENTS AND METHODS: Main Text: When used under the supervision of health professionals, technology is mostly beneficial - when harm, or no benefit is detected, the technology is withdrawn or corrected. Uncontrolled use of technology without verification and without monitoring of outcomes often leads to negative effects. Without regulation, technology continues to be used even when proven to be useless or even harmful.


Assuntos
Tecnologia Biomédica , Internet , Mídias Sociais , Tecnologia Biomédica/tendências , Pessoal de Saúde , Humanos , Software
16.
Curr Opin Anaesthesiol ; 32(4): 490-497, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31021895

RESUMO

PURPOSE OF REVIEW: Nonoperating room anesthesia (NORA) is the fastest growing segment of anesthetic practice. This review provides an overview of knowledge and trends that will need to be introduced to residents as part of their education. RECENT FINDINGS: Topics for the future include, but are not limited to, new medications, artificial intelligence and big data, monitoring depth of hypnosis, translational innovation and collaboration, demographic changes, financial driving forces, destination hubs, medical tourism, and new approaches to education training and self-management. SUMMARY: Implementing new medical technologies for anesthesia outside the operating room will help to successfully master this ever evolving subspecialty. Anesthesiologists require specific preparation for the diverse settings that they will encounter during their training. In this rapidly changing field, cognitive fitness must be factored into teaching and evaluation of residents. We describe the most important topics to consider when educating anesthesiology residents, and highlight research that addresses upcoming challenges.


Assuntos
Anestesia/tendências , Anestesiologia/educação , Tecnologia Biomédica/tendências , Previsões , Internato e Residência , Anestesia/métodos , Anestesiologistas/educação , Anestesiologistas/tendências , Anestesiologia/tendências , Anestésicos/administração & dosagem , Difusão de Inovações , Humanos
20.
Cad Saude Publica ; 35(3): e00153118, 2019 03 25.
Artigo em Inglês, Português | MEDLINE | ID: mdl-30916181

RESUMO

The enormous development of genomics research in recent decades has raised great expectations concerning its impact on biomedicine. There has been growing investment in research in personalized or precision medicine, which aims to customize medical practice with a focus on the individual, based on the use of genetic tests, identification of biomarkers, and development of targeted drugs. However, the personalized or precision medicine movement is controversial and has sparked an important debate between its defenders and critics. This essay aims to discuss the assumptions, promises, limits, and possibilities of personalized or precision medicine based on a review of the recent literature situating the debate on the theme. The review indicates that many of the promises of personalized or precision medicine remain unfulfilled. While there has been huge progress in knowledge on the molecular mechanisms of diseases and the development of drugs that have significantly impacted the treatment of some types of cancer, thus far there is no evidence that this same pattern will be reproduced in other complex diseases. Personalized or precision medicine is expected to generate incremental developments in specific areas of medicine, but there are obstacles to its generalization. The high cost of new biotechnologies can exacerbate health inequalities and become a problem for health services' sustainability, especially in low and middle-income countries. The emphasis on personalized or precision medicine may shift funds away from less costly interventions that have greater public health impact.


Assuntos
Tecnologia Biomédica/tendências , Medicina de Precisão/tendências , Tecnologia Biomédica/economia , Genômica/economia , Genômica/métodos , Equidade em Saúde , Humanos , Neoplasias/economia , Neoplasias/terapia , Preparações Farmacêuticas/economia , Medicina de Precisão/economia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA