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1.
PLoS One ; 16(7): e0253890, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34197523

RESUMO

BACKGROUND: During COVID-19, the public actively sought non-pharmacological and self-management approaches to prevent infection. Little is known on the use of traditional, complementary and integrative medicine (TCIM) by the public as preventive measures. This study investigated the prevalence and patterns of TCIM use during the pandemic, and identified factors associated with its use among the general population in Hong Kong. METHODS: An online cross-sectional survey was conducted from November to December 2020. The survey solicited information on the respondents' sociodemographic characteristics, risk perception of the pandemic, and use of TCIM before and during the pandemic. Logistic regression analysis was conducted to determine predictors of TCIM use. RESULTS: In total, 632 responses (completion rate = 88.1%) were analyzed. TCIM was used by 44.0% of respondents during the pandemic. The most popular forms of TCIM were vitamins or other dietary supplements (n = 160, 25.3%) and Chinese herbal medicine (n = 122, 19.3%) during the pandemic. The most frequently reported indication was strengthening the immune system, especially for vitamins or other dietary supplements (n = 142/160, 88.8%). Respondents who reported using TCIM were more likely to be female (adjusted odds ratio [aOR] = 1.82, 95% confidence interval [CI] = 1.29-2.59), had higher education attainment (aOR = 2.21, 95% CI = 1.39-3.59), and older-aged (age >55 years: aOR = 1.77, 95% CI = 1.04-3.02). Respondents who resided in districts with moderate to high number of confirmed COVID-19 cases (aOR = 1.60, 95% CI = 1.07-2.42) and had a higher level of risk perception (aOR = 1.04, 95% CI = 1.01-1.07) were also more likely to use TCIM. CONCLUSION: TCIM was used commonly in Hong Kong during the COVID-19 pandemic. While vaccination and social distancing remain the mainstay of controlling the pandemic, professional bodies should proactively consider public preferences and provide information regarding the effectiveness and safety of TCIM for COVID-19 prevention and treatment.


Assuntos
COVID-19/terapia , Terapias Complementares , Medicina Integrativa , Adolescente , Adulto , COVID-19/epidemiologia , COVID-19/prevenção & controle , Estudos Transversais , Suplementos Nutricionais , Feminino , Hong Kong/epidemiologia , Humanos , Masculino , Medicina Tradicional Chinesa , Pessoa de Meia-Idade , Pandemias , Vitaminas/uso terapêutico , Adulto Jovem
2.
Molecules ; 26(11)2021 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-34205972

RESUMO

Nowadays, most people who lead healthy lifestyles tend to use natural products as supplements, complementary medicine or alternative treatments. Honey is God's precious gift to mankind. Honey has been highly appreciated and extensively used since ancient history due to its high nutritional and therapeutic values. It is also known to enhance fertility. In the last few decades, the important role of honey in modern medicine has been acknowledged due to the large body of convincing evidence derived from extensive laboratory studies and clinical investigations. Honey has a highly complex chemical and biological composition that consists of various essential bioactive compounds, enzymes, amino and organic acids, acid phosphorylase, phytochemicals, carotenoid-like substances, vitamins and minerals. Reproductive health and fertility rates have declined in the last 30 years. Therefore, this review aimed to highlight the protective role of honey as a potential therapeutic in maintaining reproductive health. The main role of honey is to enhance fertility and treat infertility problems by acting as an alternative to hormone replacement therapy for protecting the vagina and uterus from atrophy, protecting against the toxic effects of xeno-oestrogenic agents on female reproductive functions and helping in the treatment of gynaecological disorders, such as vulvovaginal candidiasis infection, that affect women's lives.


Assuntos
Fertilidade/efeitos dos fármacos , Mel/análise , Substâncias Protetoras/farmacologia , Produtos Biológicos/farmacologia , Terapias Complementares , Humanos , Valor Nutritivo , Saúde Reprodutiva
3.
Anticancer Res ; 41(7): 3233-3246, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34230117

RESUMO

BACKGROUND/AIM: Upper limb breast cancer-related lymphedema (BCRL) is a chronic and severe condition affecting a significant percentage of breast cancer survivors. Even though its physiopathology is well-known, there is no worldwide consensus on BCRL evaluation and a gold-standard treatment. This narrative review aims at providing a brief descriptive overview with regard to BCRL treatment modalities. MATERIALS AND METHODS: We conducted a literature search within the PubMed database, and 33 articles out of 56 were selected, including reviews, systematic reviews, and meta-analyses aiming find the most updated evidence regarding BCRL treatment modalities. RESULTS: Physical exercise (aerobic exercise, resistance exercise, aquatic therapy), bandages, and intermittent pneumatic compression were shown to be most effective in BCRL patients, in terms of swelling reduction in the acute-intensive phase. Furthermore, physical exercise was beneficial also as a maintenance tool. Manual lymphatic drainage demonstrated efficacy in preventing secondary lymphedema if applied immediately after breast cancer surgery or in early phases of BCRL or as a maintenance tool. Complementary procedures such as acupuncture, reflexology, yoga and photo-biomodulation therapy did not show conclusive results in BCRL treatment. Surgery was shown effective in managing symptoms (liposuction), preventing (lymphaticovenular anastomosis) and treating BCRL (vascularized lymph node transfer). CONCLUSION: BCRL is still a challenging condition either for breast cancer survivors and clinicians, deeply impacting patient functioning and quality of life. Due to the lack of globally accepted criteria in evaluating BCRL, to date a gold standard treatment for this widespread issue is still needed.


Assuntos
Linfedema Relacionado a Câncer de Mama/terapia , Neoplasias da Mama/cirurgia , Linfedema Relacionado a Câncer de Mama/fisiopatologia , Neoplasias da Mama/fisiopatologia , Terapias Complementares/métodos , Exercício Físico/fisiologia , Feminino , Humanos , Sobreviventes
4.
Artigo em Inglês | PAHO-IRIS | ID: phr-54427

RESUMO

[ABSTRACT]. Access to information and intercultural approaches in the field of health are essential for the elimination of inequities in health access and care. Intercultural models such as traditional, complementary, and integrative medicine (TCIM) are an important part of health care in most countries and often contribute to expanding access to primary health care. Despite legal recognition and policies to integrate TCIM into health systems, their contribution to health, well-being, and people-centered care to achieve universal health is still underestimated. This article presents the progress (2017-2020) achieved by the Virtual Health Library specialized in the TCIM (VHL TCIM Americas), an initiative created as a tool to reduce the gaps in the production and access to validated information on TCIM. Through collaborative network work, VHL TCIM Americas contributes to the democratization of health, access to verified scientific data, visibility of non-conventional knowledge, strengthening of research capacities, and exchange of experiences for informed decision-making.


[RESUMEN]. El acceso a la información y los abordajes interculturales en el ámbito de la salud son esenciales para la eliminación de inequidades en el acceso a los servicios de salud y la atención sanitaria. Los modelos interculturales, como las medicinas tradicionales, complementarias e integrativas (MTCI) son una parte importante del cuidado de la salud en la mayoría de los países y frecuentemente contribuyen a ampliar el acceso a la atención primaria de salud. A pesar del reconocimiento legal y de la existencia de políticas para la integración de las MTCI en los sistemas de salud, aún se subestima su contribución a la salud, el bienestar y la atención de la salud centrada en las personas para alcanzar la salud universal. En este artículo se presentan los avances (2017-2020) alcanzados por la Biblioteca Virtual en Salud especializada en las MTCI (BVS MTCI Américas), iniciativa creada como herramienta para disminuir las brechas en la producción y el acceso a la información validada sobre las MTCI. Mediante el trabajo colaborativo en red, la BVS MTCI Américas contribuye a la democratización de la salud, el acceso a datos científicos verificados disponibles, la visibilización de conocimientos no convencionales, el fortalecimiento de capacidades de investigación y el intercambio de experiencias para la toma informada de decisiones.


[RESUMO]. O acesso à informação e as abordagens interculturais no setor da saúde são essenciais para eliminar as desigualdades no acesso aos serviços de saúde. Os modelos interculturais, como as medicinas tradicionais, complementares e integrativas (MTCI), são uma parte importante da atenção à saúde na maioria dos países e frequentemente contribuem para ampliar o acesso à atenção primária. Apesar do reconhecimento legal e da existência de políticas para a integração das MTCI nos sistemas de saúde, a sua contribuição para a saúde, o bem-estar e a atenção centrada nas pessoas para alcançar a saúde universal ainda é subestimada. Este artigo apresenta o progresso (de 2017 a 2020) alcançado pela Biblioteca Virtual em Saúde especializada em MTCI (BVS MTCI Américas), uma iniciativa criada como ferramenta para reduzir as disparidades na produção e no acesso a informações validadas sobre as MTCI. Realizando um trabalho colaborativo em rede, a BVS MTCI Américas contribui para a democratização da saúde, o acesso a dados científicos verificados, a visibilidade dos conhecimentos não convencionais, o fortalecimento das capacidades de pesquisa e a troca de experiências para a tomada de decisões bem informada.


Assuntos
Medicina Tradicional , Terapias Complementares , Assistência Integral à Saúde , Equidade em Saúde , Acesso à Informação , Bibliotecas Digitais , Medicina Tradicional , Terapias Complementares , Assistência Integral à Saúde , Equidade em Saúde , Acesso à Informação , Bibliotecas Digitais , Terapias Complementares , Assistência Integral à Saúde , Equidade em Saúde , Acesso à Informação , Bibliotecas Digitais
5.
Medicine (Baltimore) ; 100(25): e26397, 2021 Jun 25.
Artigo em Inglês | MEDLINE | ID: mdl-34160423

RESUMO

BACKGROUND: Dementia is causing a huge medical and socioeconomic burden. Along with strategies to delay cognitive decline in dementia, behavioral and psychological symptoms of dementia (BPSD) are major contributing factor to the burden of dementia, and have been an important clinical issue for successful management of dementia. However, pharmacological strategies such as antipsychotics raise concerns in terms of risk-to-benefit ratio in managing BPSD. Therefore, there is a need for an effective and safe alternative in BPSD management. From this point of view, various complementary and alternative medicines (CAMs) are attracting attention in BPSD management. Therefore, the overview will make it possible to evaluate the feasibility of using CAM as a potential treatment strategy for BPSD in terms of evidence-based medicine. METHODS AND ANALYSIS: Comprehensive searching will be performed in 13 bibliographic databases from their inception dates to November 2021. Systematic reviews and/or meta-analyses that examined the effectiveness and safety of CAM modalities including herbal medicine, acupuncture, acupressure, aromatherapy, meditation, and relaxation on BPSD, will be included. The methodological quality of included reviews will be assessed by using the A MeaSurement Tool to Assess systematic Reviews-2. Two independent researchers will conduct study search, study selection, data extraction, and quality assessment processes. RESULTS: The results of overview will be disseminated by the publication of a manuscript in a peer-reviewed journal or presentation at a relevant conference. CONCLUSION: The findings of this overview will help to solve the major public health problem related to dementia, and will provide patients with dementia, their caregivers, clinicians, and health policy makers credible evidence in mitigating the burden of dementia. ETHICS AND DISSEMINATION: As this protocol is for an overview of systematic reviews and meta-analyses, ethical approval is not required. PROTOCOL REGISTRATION NUMBER: Open Science Framework registry (https://osf.io/g5f3m).


Assuntos
Terapias Complementares/métodos , Demência/terapia , Terapias Complementares/efeitos adversos , Demência/diagnóstico , Demência/epidemiologia , Demência/psicologia , Estudos de Viabilidade , Carga Global da Doença , Humanos , Metanálise como Assunto , Revisões Sistemáticas como Assunto , Resultado do Tratamento
6.
Rev Bras Enferm ; 74(2): e20200449, 2021.
Artigo em Inglês, Português | MEDLINE | ID: mdl-34076217

RESUMO

OBJECTIVE: Report the implementation of integrative and complementary practices in a Nursing course at a federal university in the fields of teaching, research and extension. METHOD: As a reference, the concept of nursing care anchored in the integrality and the avant-garde legacy of Florence Nightingale was used. The report is structured in two topics: the first describes the experience itself, and the second brings a critical reflection about the limits, achievements and challenges. RESULTS: The interaction of integrative practices in nursing and its insertion in teaching, research and extension corroborate holistic care, favor the construction of scientific knowledge in the area and potentially requalify professional training. FINAL CONSIDERATIONS: The insertion of integrative and complementary practices in nursing education can contribute to the consolidation of an integral model of care in SUS towards access and comprehensiveness.


Assuntos
Terapias Complementares , Educação em Enfermagem , Currículo , Humanos , Conhecimento
7.
Harefuah ; 160(6): 399, 2021 Jun.
Artigo em Hebraico | MEDLINE | ID: mdl-34160160
8.
Phytomedicine ; 88: 153584, 2021 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-34119741

RESUMO

BACKGROUND: Proton pump inhibitors (PPIs) play an important role in the treatment of nonerosive reflux disease (NERD), but their long-term and excessive uses have been associated with safety concerns. Chinese herbal medicine (CHM) has become a popular alternative treatment for this condition. METHODS: A total of 204 patients were randomly assigned to the combination group or PPI group (1:1 ratio). They were given JianpiQinghua (JQ) granules (34.8 g) plus omeprazole (10 mg) plus dummy omeprazole (10 mg) or dummy JQ granules (34.8 g) plus omeprazole (20 mg) daily for 4 weeks. The primary endpoints were the rate of sufficient relief and complete resolution of GERD Q at week 4. Metabonomics and the gut microbiota were also assessed. RESULTS: Complete resolution was observed in 40.8% of patients in the combination group and 26.8% of patients in the PPI group after 4 weeks (FAS analysis, OR, 1.88; 95% CI, 1.03-3.44; p = 0.039). Sufficient relief was observed in 50% of patients in the combination group and 43.30% of patients in the PPI group after 4 weeks (FAS analysis, OR, 1.31; 95% CI, 0.74-2.30; p = 0.35). Three patients had liver dysfunction, one of whom had a mild case and 2 of whom had moderate-to-severe cases in the combination group. Patients in the combination group showed a significant increase in richness and diversity of their gut microbiota compared with those in the PPI group. Metabonomics showed that the combination therapy could correct the glutamate metabolism pathway. CONCLUSION: Our findings demonstrate the superior efficacy of JQ granules combined with omeprazole (10 mg) vs. omeprazole (20 mg) in terms of symptom relief in patients with NERD. TRIAL REGISTRATION: ClinicalTrials.gov number NCT02892357. Registered on 14 February 2019.


Assuntos
Medicamentos de Ervas Chinesas/uso terapêutico , Refluxo Gastroesofágico/tratamento farmacológico , Omeprazol/administração & dosagem , Inibidores da Bomba de Prótons/administração & dosagem , Adulto , Terapias Complementares , Método Duplo-Cego , Feminino , Refluxo Gastroesofágico/etiologia , Fármacos Gastrointestinais/uso terapêutico , Humanos , Masculino , Pessoa de Meia-Idade , Omeprazol/uso terapêutico , Inibidores da Bomba de Prótons/uso terapêutico , Resultado do Tratamento
9.
Enferm. foco (Brasília) ; 12(1): 154-162, jun. 2021. tab, ilus
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1255354

RESUMO

Objetivos: Identificar trabalhos científicos que abordem a utilização das Práticas Integrativas e Complementares em crianças, como forma do cuidado em saúde. Métodos: Revisão integrativa conduzida nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde, Medical Literature Analysis and Retrieval System Online, Scientific Electronic Library Online e Base de Dados de Enfermagem em maio de 2020. A avaliação, do nível de evidência, foi obtida por meio do método Oxford Centre for Evidence-based Medicine. Resultados: Onze estudos atenderam aos critérios estabelecidos. A literatura científica carece de dados que permitam caracterizar o uso das terapias complementares, no público infantil, com uma maior consistência. Mesmo assim, foi possível detectar a variedade dessas, bem como a prevalência. Conclusões: As práticas Integrativas e Complementares fundamentam-se em um reducionismo biológico e constituem hoje um importante aliado no fortalecimento das políticas públicas de saúde. Em virtude disso, é bastante usada em crianças devido ao impacto benéfico em suas vidas. (AU)


Objectives: To identify scientific works that address the use of Integrative and Complementary Practices in children, as a form of health care. Methods: Integrative review conducted in the databases of Latin American and Caribbean Literature in Health Sciences, Medical Literature Analysis and Retrieval System Online, Scientific Electronic Library Online and Nursing Database in May 2020. The assessment, of the level of evidence, was obtained using the Oxford Center for Evidence-based Medicine method. Results: Eleven studies met the established criteria. The scientific literature lacks data to characterize the use of complementary therapies, in children, with greater consistency. Even so, it was possible to detect the variety of these, as well as the prevalence. Conclusions: Integrative and Complementary practices are based on biological reductionism and today constitute an important ally in strengthening public health policies. As a result, it is widely used in children due to the beneficial impact on their lives. (AU)


Objetivos: identificar trabajos científicos que aborden el uso de prácticas integradoras y complementarias en los niños, como una forma de atención médica. Métodos: Revisión integradora realizada en las bases de datos de Literatura Latinoamericana y del Caribe en Ciencias de la Salud, Sistema de Análisis y Recuperación de Literatura Médica en línea, Biblioteca electrónica científica en línea y Base de datos de enfermería en mayo de 2020. La evaluación, del nivel de La evidencia se obtuvo utilizando el método del Centro de Oxford para la Medicina basada en la Evidencia. Resultados: Once estudios cumplieron los criterios establecidos. La literatura científica carece de datos para caracterizar el uso de terapias complementarias, en niños, con mayor consistencia. Aun así, fue posible detectar la variedad de estos, así como la prevalencia. Conclusiones: las prácticas integradoras y complementarias se basan en el reduccionismo biológico y hoy son un aliado importante para fortalecer las políticas de salud pública. Como resultado, se usa ampliamente en niños debido al impacto beneficioso en sus vidas. (AU)


Assuntos
Terapias Complementares , Criança , Enfermagem
10.
Eur J Obstet Gynecol Reprod Biol ; 262: 7-12, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33984728

RESUMO

OBJECTIVE: This study aimed to provide an overview of the extent to which women with endometriosis are informed about, interested in, and make use of CAM, and to evaluate which of the methods are most often applied. STUDY DESIGN: A retrospective, two-center cohort study was conducted using a validated questionnaire among women with laparoscopically confirmed endometriosis at two urban teaching hospitals, certified as endometriosis centres. RESULTS: A total of 592 patients were included in the study and received the questionnaire; 114 (19.3 %) were included in the data analysis. Most of the women were not receiving hormone therapy at the time of the study (n = 60, 52.6 %). Most (n = 75, 65.8 %) were interested in CAM, but only a minority (n = 12, 10.5 %) had detailed knowledge about it. A total of 81 patients (71.1 %) had used at least one CAM method for disease management; the five most frequently used CAM methods were exercise (n = 55, 48.2 %), vitamins (n = 40, 35.1 %), yoga (n = 38, 33.3 %), homeopathy (n = 32, 28.1 %), and trace elements (n = 27, 23.7 %). CONCLUSIONS: In our study population, women with endometriosis are strongly interested in using CAM, but have only limited information about it. Nevertheless, a majority of the patients had used at least one CAM method to relieve symptoms associated with the disease and the most often used was exercise.


Assuntos
Terapias Complementares , Endometriose , Estudos de Coortes , Feminino , Humanos , Estudos Retrospectivos , Inquéritos e Questionários
11.
Curr Opin Ophthalmol ; 32(4): 348-361, 2021 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-34010229

RESUMO

PURPOSE OF REVIEW: Dry eye disease (DED) is a multifactorial disease affecting approximately 5-50% of individuals in various populations. Contributors to DED include, but are not limited to, lacrimal gland hypofunction, meibomian gland dysfunction (MGD), ocular surface inflammation, and corneal nerve dysfunction. Current DED treatments target some facets of the disease, such as ocular surface inflammation, but not all individuals experience adequate symptom relief. As such, this review focuses on alternative and adjunct approaches that are being explored to target underlying contributors to DED. RECENT FINDINGS: Neuromodulation, stem cell treatments, and oral royal jelly have all been studied in individuals with DED and lacrimal gland hypofunction, with promising results. In individuals with MGD, devices that provide eyelid warming or intense pulsed light therapy may reduce DED symptoms and signs, as may topical Manuka honey. For those with ocular surface inflammation, naturally derived anti-inflammatory agents may be helpful, with the compound trehalose being farthest along in the process of investigation. Nerve growth factor, blood-derived products, corneal neurotization, and to a lesser degree, fatty acids have been studied in individuals with DED and neurotrophic keratitis (i.e. corneal nerve hyposensitivity). Various adjuvant therapies have been investigated in individuals with DED with neuropathic pain (i.e. corneal nerve hypersensitivity) including nerve blocks, neurostimulation, botulinum toxin, and acupuncture, although study numbers and design are generally weaker than for the other DED sub-types. SUMMARY: Several alternatives and adjunct DED therapies are being investigated that target various aspects of disease. For many, more robust studies are required to assess their sustainability and applicability.


Assuntos
Terapias Complementares/métodos , Síndromes do Olho Seco/terapia , Aparelho Lacrimal/diagnóstico por imagem , Síndromes do Olho Seco/diagnóstico , Humanos
12.
Front Immunol ; 12: 637553, 2021.
Artigo em Inglês | MEDLINE | ID: covidwho-1247858

RESUMO

Plants have been extensively studied since ancient times and numerous important chemical constituents with tremendous therapeutic potential are identified. Attacks of microorganisms including viruses and bacteria can be counteracted with an efficient immune system and therefore, stimulation of body's defense mechanism against infections has been proven to be an effective approach. Polysaccharides, terpenoids, flavonoids, alkaloids, glycosides, and lactones are the important phytochemicals, reported to be primarily responsible for immunomodulation activity of the plants. These phytochemicals may act as lead molecules for the development of safe and effective immunomodulators as potential remedies for the prevention and cure of viral diseases. Natural products are known to primarily modulate the immune system in nonspecific ways. A number of plant-based principles have been identified and isolated with potential immunomodulation activity which justify their use in traditional folklore medicine and can form the basis of further specified research. The aim of the current review is to describe and highlight the immunomodulation potential of certain plants along with their bioactive chemical constituents. Relevant literatures of recent years were searched from commonly employed scientific databases on the basis of their ethnopharmacological use. Most of the plants displaying considerable immunomodulation activity are summarized along with their possible mechanisms. These discussions shall hopefully elicit the attention of researchers and encourage further studies on these plant-based immunomodulation products as potential therapy for the management of infectious diseases, including viral ones such as COVID-19.


Assuntos
Produtos Biológicos/uso terapêutico , COVID-19/tratamento farmacológico , Terapias Complementares/métodos , Fitoterapia/métodos , Preparações de Plantas/uso terapêutico , SARS-CoV-2/fisiologia , Viroses/tratamento farmacológico , Animais , Humanos , Imunomodulação , Plantas Medicinais , Terpenos/uso terapêutico
13.
J Evid Based Integr Med ; 26: 2515690X211020685, 2021.
Artigo em Inglês | MEDLINE | ID: covidwho-1247472

RESUMO

The retrospective cohort study aimed to evaluate the clinical outcomes of Ayurveda treatment exposure as an add-on to conventional care in early stage COVID-19 patients admitted at Samaras COVID care center, Ahmedabad, India. Conventional care included Vitamin-c, Azithromycin, and Paracetamol. Ayurveda formulations used as add-on were Dashamula and Pathyadi decoctions along with Trikatu powder, Sanshamani tablet, AYUSH-64 tablet AND Yastimadhu Ghana tablet for oral administration. Considering Add-on Ayurveda medicines as exposure of interest, patients who received Add-on Ayurveda medicines at least for 7 days were included in the exposed group while those who received only conventional care in unexposed group. Data was collected through record review and telephonic interviews. The outcomes of interest were the development of symptoms, duration of symptomatic phase in those progressing to symptomatic stage and mortality. Total 762 participants were included-[541 (71%) in the exposed group and 221 (29%) in the unexposed. Progression to symptomatic phase did not differ significantly between groups [27.6% in exposed, 24.6% in unexposed, adjusted RR 0.85; 95% CI 0.6-1.2]. The total duration of symptomatic phase among those progressing to the symptomatic stage was significantly decreased in the exposed group (x¯ = 3.66 ± 1.55 days in exposed (n = 133); x¯ = 5.34 ± 3.35 days in unexposed (n = 61), p < 0.001). No mortality was observed in either of the groups. Ayurveda Treatment as adjunctive to conventional care reduced the duration of symptomatic phase in early stage COVID-19 as compared to standalone conventional care. Add-on Ayurveda treatment has promising potential for management of early stage COVID-19.


Assuntos
Acetaminofen/uso terapêutico , COVID-19 , Medicina Ayurvédica/métodos , Extratos Vegetais/uso terapêutico , Preparações de Plantas/uso terapêutico , Antipiréticos/uso terapêutico , Antivirais/uso terapêutico , COVID-19/diagnóstico , COVID-19/tratamento farmacológico , COVID-19/epidemiologia , Terapias Complementares/métodos , Quimioterapia Combinada/métodos , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Índia/epidemiologia , Masculino , Pessoa de Meia-Idade , Gravidade do Paciente , Estudos Retrospectivos , SARS-CoV-2/isolamento & purificação , Resultado do Tratamento
15.
Front Immunol ; 12: 637553, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34054806

RESUMO

Plants have been extensively studied since ancient times and numerous important chemical constituents with tremendous therapeutic potential are identified. Attacks of microorganisms including viruses and bacteria can be counteracted with an efficient immune system and therefore, stimulation of body's defense mechanism against infections has been proven to be an effective approach. Polysaccharides, terpenoids, flavonoids, alkaloids, glycosides, and lactones are the important phytochemicals, reported to be primarily responsible for immunomodulation activity of the plants. These phytochemicals may act as lead molecules for the development of safe and effective immunomodulators as potential remedies for the prevention and cure of viral diseases. Natural products are known to primarily modulate the immune system in nonspecific ways. A number of plant-based principles have been identified and isolated with potential immunomodulation activity which justify their use in traditional folklore medicine and can form the basis of further specified research. The aim of the current review is to describe and highlight the immunomodulation potential of certain plants along with their bioactive chemical constituents. Relevant literatures of recent years were searched from commonly employed scientific databases on the basis of their ethnopharmacological use. Most of the plants displaying considerable immunomodulation activity are summarized along with their possible mechanisms. These discussions shall hopefully elicit the attention of researchers and encourage further studies on these plant-based immunomodulation products as potential therapy for the management of infectious diseases, including viral ones such as COVID-19.


Assuntos
Produtos Biológicos/uso terapêutico , COVID-19/tratamento farmacológico , Terapias Complementares/métodos , Fitoterapia/métodos , Preparações de Plantas/uso terapêutico , SARS-CoV-2/fisiologia , Viroses/tratamento farmacológico , Animais , Humanos , Imunomodulação , Plantas Medicinais , Terpenos/uso terapêutico
16.
J Evid Based Integr Med ; 26: 2515690X211020685, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34057365

RESUMO

The retrospective cohort study aimed to evaluate the clinical outcomes of Ayurveda treatment exposure as an add-on to conventional care in early stage COVID-19 patients admitted at Samaras COVID care center, Ahmedabad, India. Conventional care included Vitamin-c, Azithromycin, and Paracetamol. Ayurveda formulations used as add-on were Dashamula and Pathyadi decoctions along with Trikatu powder, Sanshamani tablet, AYUSH-64 tablet AND Yastimadhu Ghana tablet for oral administration. Considering Add-on Ayurveda medicines as exposure of interest, patients who received Add-on Ayurveda medicines at least for 7 days were included in the exposed group while those who received only conventional care in unexposed group. Data was collected through record review and telephonic interviews. The outcomes of interest were the development of symptoms, duration of symptomatic phase in those progressing to symptomatic stage and mortality. Total 762 participants were included-[541 (71%) in the exposed group and 221 (29%) in the unexposed. Progression to symptomatic phase did not differ significantly between groups [27.6% in exposed, 24.6% in unexposed, adjusted RR 0.85; 95% CI 0.6-1.2]. The total duration of symptomatic phase among those progressing to the symptomatic stage was significantly decreased in the exposed group (x¯ = 3.66 ± 1.55 days in exposed (n = 133); x¯ = 5.34 ± 3.35 days in unexposed (n = 61), p < 0.001). No mortality was observed in either of the groups. Ayurveda Treatment as adjunctive to conventional care reduced the duration of symptomatic phase in early stage COVID-19 as compared to standalone conventional care. Add-on Ayurveda treatment has promising potential for management of early stage COVID-19.


Assuntos
Acetaminofen/uso terapêutico , COVID-19 , Medicina Ayurvédica/métodos , Extratos Vegetais/uso terapêutico , Preparações de Plantas/uso terapêutico , Antipiréticos/uso terapêutico , Antivirais/uso terapêutico , COVID-19/diagnóstico , COVID-19/tratamento farmacológico , COVID-19/epidemiologia , Terapias Complementares/métodos , Quimioterapia Combinada/métodos , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Índia/epidemiologia , Masculino , Pessoa de Meia-Idade , Gravidade do Paciente , Estudos Retrospectivos , SARS-CoV-2/isolamento & purificação , Resultado do Tratamento
17.
Curr Neurol Neurosci Rep ; 21(7): 33, 2021 05 10.
Artigo em Inglês | MEDLINE | ID: mdl-33970348

RESUMO

PURPOSE OF REVIEW: Headache affects and disables at least 1 billion people worldwide. Patients and providers seek new therapies to relieve headache without the side effects and financial burden of current treatments. This narrative review highlights recent treatment advances in integrative headache medicine: nutraceuticals and behavioral therapies. RECENT FINDINGS: Growing use of complementary and alternative medicine (CAM) therapies for headache (riboflavin, coenzyme Q10, magnesium, vitamin D, melatonin) alongside mainstream treatments is increasing with improving evidence of quality, safety, and tolerability. Increasing interest in medical cannabis is tempered by lack of evidence regarding safety and efficacy. Behavioral therapies including cognitive behavioral therapy (CBT), biofeedback, mindfulness-based stress reduction (MBSR), and acceptance and commitment therapy (ACT) improve patient resiliency and self-efficacy outcomes and reduce disability. The body of evidence for nutraceutical and behavioral CAM interventions for headache continues to grow and improve in quality. Providers and patients should educate themselves regarding CAM therapies as part of integrative headache management. Future studies should examine combinatorial trials of CAM therapies against current standards of headache care.


Assuntos
Terapia de Aceitação e Compromisso , Terapias Complementares , Terapia Comportamental , Suplementos Nutricionais , Cefaleia/terapia , Humanos
18.
Medicine (Baltimore) ; 100(18): e25769, 2021 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-33950966

RESUMO

BACKGROUND: Scapulohumeral periarthritis is a disease with high incidence and great pain. The current western treatments with many side effects, poor efficacy cannot fundamentally solve the problem. Complementary and alternative therapies have played an excellent role in the treatment of scapulohumeral periarthritis. However, it is not clear which complementary and alternative therapy is more effective. Therefore, we propose a protocol to compare the efficacy and safety of various complementary and alternative therapies through network meta-analysis (NMA) to provide choice guidance for the therapy. METHODS: A comprehensive search will be conducted for randomized controlled trials of complementary and alternative therapy for scapulohumeral periarthritis as well as ongoing trials. The time limit is from the establishment of the database until January 2021. Literature and data extraction were completed independently by two researchers. Through pairwise comparison and meta-analysis of Bayesian NMA, all the evidences are evaluated comprehensively. STATA16.0 and WinBUGS1.4.3 software will be used for data processing and analysis, and recommendation evaluation will be used to develop and assess grades to classify the quality of NMA evidence. RESULTS: Through the analysis, we will obtain the ranking of the efficacy and safety of different complementary and alternative therapies in the treatment of scapulohumeral periarthritis, in order to provide reference for clinical selection of treatment methods. CONCLUSION: Complementary and alternative therapies of scapulohumeral periarthritis plays a positive role in improving the symptoms of scapulohumeral periarthritis. This study can provide evidence support for clinicians and patients.International Platform of Registered Systematic Review and Meta-Analysis Protocols registration number: INPLASY202140044.


Assuntos
Terapias Complementares/métodos , Periartrite/terapia , Dor de Ombro/terapia , Teorema de Bayes , Doença Crônica/terapia , Terapias Complementares/efeitos adversos , Humanos , Metanálise como Assunto , Medição da Dor , Periartrite/complicações , Periartrite/imunologia , Periartrite/patologia , Ensaios Clínicos Controlados Aleatórios como Assunto , Articulação do Ombro/imunologia , Articulação do Ombro/patologia , Dor de Ombro/diagnóstico , Dor de Ombro/etiologia , Resultado do Tratamento
20.
Recurso na Internet em Português | LIS - Localizador de Informação em Saúde | ID: lis-48186

RESUMO

Este mapa de evidências científicas apresenta uma síntese gráfica de estudos clínicos sobre a aplicação da Medicina Tradicional Chinesa para desfechos de obesidade e sobrepeso, e tabagismo. A partir de uma ampla busca bibliográfica 03 ensaios clínicos randomizados (ECR) foram incluídos no mapa e categorizados por tipo de intervenção e por desfechos. Os estudos avaliaram o efeito de 03 tipos de intervenção: Tai chi, Qigong e Terapias combinadas. Principais Achados: Os estudos foram realizados entre 2007 e 2015 nos seguintes países: Hong Kong, Estados Unidos da América e França. Não foram encontradas revisões sistemáticas sobre as intervenções. Também não foram encontrados ensaios clínicos randomizados (ECR) para os desfechos de tabagismo. Embora existam alguns resultados favoráveis à prática de tai Tai chi, é pequena a evidência de eficácia e segurança da prática de Medicina Tradicional Chinesa no tratamento da obesidade em adultos e idosos. A avaliação metodológica dos ECR mostrou alto risco de viés de alocação em um estudo, risco de viés de alocação incerto e alto risco de viés de atrito em outro estudo, e risco de viés incerto para randomização e alocação no terceiro estudo.


Assuntos
Medicina Tradicional Chinesa/métodos , Obesidade/terapia , Tai Ji/métodos , Terapias Complementares/métodos , Tabagismo/terapia
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