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1.
World Neurosurg ; 133: 185-187, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31606509

RESUMO

We report a rare case of bony diastematomyelia associated with intraspinal teratoma. The patient was surgically treated with bony diastematomyelia and intradural teratoma resection, followed by lumbar duroplasty, and posterior fusion from L2-L4 in order to maintain the spinal stability of the approached segments. Despite the risks, it was necessary to perform early surgical treatment because of rapid neurologic deterioration. The patient had a good postoperative outcome.


Assuntos
Vértebras Lombares/cirurgia , Defeitos do Tubo Neural/cirurgia , Neoplasias da Medula Espinal/cirurgia , Fusão Vertebral/métodos , Teratoma/cirurgia , Vértebras Torácicas/cirurgia , Adulto , Humanos , Vértebras Lombares/diagnóstico por imagem , Imagem por Ressonância Magnética , Masculino , Defeitos do Tubo Neural/complicações , Defeitos do Tubo Neural/diagnóstico por imagem , Neoplasias da Medula Espinal/complicações , Neoplasias da Medula Espinal/diagnóstico por imagem , Teratoma/complicações , Teratoma/diagnóstico por imagem , Vértebras Torácicas/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Resultado do Tratamento
2.
Pan Afr Med J ; 34: 75, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31819791

RESUMO

We describe a patient who developed nephrotic syndrome in the setting of ovarian tumor. A kidney biopsy showed minimal change nephropathy (MCN). CT scan and MR imaging followed by surgery lead to diagnostic of ovarian dermoid cyst. Surgery combined with corticosteroids resulted in a complete remission of nephrotic syndrome with disappearance of proteinuria after 3 weeks. Ten other cases of ovarian tumor associated with glomerulopathy are reviewed. This is the second case of an ovarian teratoma associated with MCN. Accurate history, physical examination, laboratory data, and kidney biopsy are highlighted in establishing the correct diagnosis in such patients.


Assuntos
Nefrose Lipoide/diagnóstico , Síndrome Nefrótica/diagnóstico , Neoplasias Ovarianas/diagnóstico , Teratoma/diagnóstico , Feminino , Humanos , Imagem por Ressonância Magnética , Pessoa de Meia-Idade , Nefrose Lipoide/etiologia , Síndrome Nefrótica/etiologia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/terapia , Proteinúria/etiologia , Indução de Remissão , Teratoma/complicações , Teratoma/terapia , Tomografia Computadorizada por Raios X
3.
Medicine (Baltimore) ; 98(46): e17856, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31725626

RESUMO

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a paraneoplastic limbic encephalitis, recently identified.To summarize our experience in the nursing care of patients with anti-NMDAR encephalitis managed with surgery and pharmacotherapy.This study included 45 patients treated between July 2015 and November 2016. Laparoscopic oophorocystectomy was performed in 11 female patients with teratomas. Eleven patients required tracheal intubation or tracheotomy and ventilation.The patients were hospitalized for an average of 25.2 days. The mental and neurological symptoms were significantly relieved 23.6 ± 4.8 days after surgery or immunotherapy. Near-normal function was restored in 11 patients, while 34 patients had varying degrees of dysfunction at discharge. After follow-up of 1 to 18 months, 24 patients were found to have permanent impairments.Appropriate symptomatic nursing care is required to ensure the safety of patients with anti-NMDAR encephalitis.


Assuntos
Encefalite Antirreceptor de N-Metil-D-Aspartato/complicações , Encefalite Antirreceptor de N-Metil-D-Aspartato/enfermagem , Adolescente , Corticosteroides/uso terapêutico , Adulto , Encefalite Antirreceptor de N-Metil-D-Aspartato/terapia , Criança , Feminino , Humanos , Imunoglobulina G/uso terapêutico , Masculino , Pessoa de Meia-Idade , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/cirurgia , Estudos Retrospectivos , Rituximab/uso terapêutico , Teratoma/complicações , Teratoma/cirurgia , Adulto Jovem
5.
BMJ Case Rep ; 12(9)2019 Sep 11.
Artigo em Inglês | MEDLINE | ID: mdl-31511263

RESUMO

Teratomas are tumour with tissue or organ components resembling normal derivatives of more than one germ layer. The most common site of congenital teratoma is sacrococcygeal region. Teratomas in head and neck region are rarer. We report a 4-day-old male baby who presented with nasopharyngeal mass, which led to respiratory distress and feeding difficulty. It was managed with surgical excision with multidisciplinary approach.


Assuntos
Neoplasias Nasofaríngeas/cirurgia , Teratoma/cirurgia , Agenesia do Corpo Caloso/complicações , Coloboma/complicações , Humanos , Recém-Nascido , Masculino , Neoplasias Nasofaríngeas/complicações , Neoplasias Nasofaríngeas/diagnóstico por imagem , Palato Duro , Teratoma/complicações , Teratoma/diagnóstico por imagem
6.
Clín. investig. ginecol. obstet. (Ed. impr.) ; 46(3): 127-130, jul.-sept. 2019. ilus
Artigo em Espanhol | IBECS | ID: ibc-182719

RESUMO

El teratoma sacrococcígeo es el tumor más común en recién nacidos, con incidencia reportada de uno por cada 40.000 nacidos vivos, habitualmente en fetos del sexo femenino, su mortalidad va del 15 al 35%, condicionada por el tamaño de la lesión, la extensión y el subtipo histológico. Se presenta un caso de teratoma sacrococcígeo diagnosticado en forma prenatal. En la región sacra se observó una imagen redondeada de bordes regulares, definidos, heterogénea, de 8,8×6,9×8,4cm, con un volumen de 266cc. El beneficio más importante es la prevención de distocias, por cesárea


Sacrococcygeal teratoma is the most common tumour found in newborns, with a reported incidence of one per 40,000 live births. It usually appears in female foetuses, with a mortality ranging from 15 to 35%, depending on the size of the lesion, extension, and histological subtype. The case is presented of a sacrococcygeal teratoma found in the prenatal diagnosis. It was observed in the sacral region as a rounded image with regular, defined, heterogeneous borders of 8.8×6.9×8.4cm, with a volume of 266cc. The most important action is the prevention of dystocia either by elective or emergency caesarean section


Assuntos
Humanos , Feminino , Gravidez , Adulto , Teratoma/diagnóstico por imagem , Diagnóstico Pré-Natal , Teratoma/complicações , Região Sacrococcígea/diagnóstico por imagem , Região Sacrococcígea/patologia , Distocia/diagnóstico por imagem , Distocia/prevenção & controle , Teratoma/cirurgia , Diagnóstico Diferencial , Angiografia
7.
BMJ Case Rep ; 12(8)2019 Aug 04.
Artigo em Inglês | MEDLINE | ID: mdl-31383677

RESUMO

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is rarely seen in women with ovarian teratoma. It is characterised by neuropsychiatric symptoms and may also cause autonomic imbalance. We present the case of a 16-year-old nulliparous woman who presented with an acute history of seizures and neurogenic bladder. Antiviral and antiepileptic therapy conferred no therapeutic benefit. A cystic pelvic mass measuring 185×140×92 mm was identified separate from the bladder. Serum titres of NMDA receptor antibodies were significantly elevated. The mass was surgically removed and histology revealed benign ovarian teratoma with NMDA receptors. The patient made a rapid improvement and had full resolution of urinary and neuropsychiatric symptoms within 1 year. This case demonstrates that increased awareness in adolescents is crucial for avoiding symptom dismissal, misdiagnosis and inappropriate treatment of this condition. Surgical removal of the teratoma should be the first line therapy of anti-NMDA-receptor encephalitis as this often leads to symptom resolution soon after.


Assuntos
Encefalite Antirreceptor de N-Metil-D-Aspartato/complicações , Neoplasias Ovarianas/complicações , Teratoma/complicações , Bexiga Urinaria Neurogênica/etiologia , Adolescente , Encefalite Antirreceptor de N-Metil-D-Aspartato/imunologia , Feminino , Humanos , Neoplasias Ovarianas/imunologia , Teratoma/imunologia , Bexiga Urinaria Neurogênica/imunologia
8.
Pediatr Surg Int ; 35(9): 979-983, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31256295

RESUMO

PURPOSE: Presacral masses associated with anorectal malformations (ARM) are most frequently dermoid or teratomas. Sacrococcygeal teratoma (SCT), in isolation, is a different condition. There are limited data comparing the two. The aim of this study was to compare presacral masses associated with ARM and isolated SCTs. METHODS: A retrospective review was performed from 1979 to 2018. Patients with presacral masses and associated ARM (n = 39) were identified and compared to patients with isolated SCTs (n = 32). RESULTS: Those with presacral mass and ARM had a lower proportion of immature and mixed teratomas by pathology and a longer time to mass resection. They had higher percentages of sacral anomalies (76% versus 9%), tethered cord (50% versus 6%), and other anomalies (51% versus 9%). For long-term bowel function, patients with presacral mass and ARM were more likely to be fecally incontinent and require enemas (59% versus 11%). Regarding isolated SCTs, 4% recurred with a time to recurrence of 7 months. CONCLUSIONS: Compared to patients with isolated SCT, patients with presacral mass and ARM had lower grade tumors. In addition, they had a higher proportion of sacral defects and other congenital defects, as well as worse bowel function outcomes.


Assuntos
Malformações Anorretais/complicações , Malformações Anorretais/patologia , Neoplasias de Tecidos Moles/complicações , Neoplasias de Tecidos Moles/patologia , Teratoma/complicações , Teratoma/patologia , Malformações Anorretais/diagnóstico , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Masculino , Estudos Retrospectivos , Região Sacrococcígea/cirurgia , Neoplasias de Tecidos Moles/diagnóstico , Teratoma/diagnóstico
10.
J Cardiothorac Surg ; 14(1): 113, 2019 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-31221172

RESUMO

BACKGROUND: Extralobar sequestration is a rare congenital malformation of lung tissue, which can be combined with other foregut and cardiac abnormalities. Our case is the first to report extralobar sequestration, absence of pericardium and atrial septal defect in the same patient. CASE PRESENTATION: A 22-year-old female with atrial septal defect came for her recent atypical symptom of intermittent palpitation and shortness of breath. Her computed tomography showed a cystic mass located in left superior anterior mediastinum near the pulmonary trunk. With specious of cystic teratoma prior to video-assisted thoracoscopic surgery, she finally was diagnosed as extralobar sequestration, while incidentally found with congenital absence of pericardium during surgery. CONCLUSIONS: Extralobar sequestration, absence of pericardium and atrial septal defect can occur in the same patient. The preoperative diagnostic rate of extralobar sequestration and asymptomatic absence of pericardium remains low attributed to atypical imaging features. A cardiac magnetic resonance imaging is highly recommended if necessary. Regular follow-up is essential to asymptomatic absence of pericardium and atrial septal defect patients. To patients with extralobar sequestration, an operation could be performed.


Assuntos
Sequestro Broncopulmonar/diagnóstico , Comunicação Interatrial/diagnóstico , Neoplasias do Mediastino/diagnóstico , Pericárdio/anormalidades , Teratoma/diagnóstico , Anormalidades Múltiplas/diagnóstico , Anormalidades Múltiplas/diagnóstico por imagem , Anormalidades Múltiplas/cirurgia , Sequestro Broncopulmonar/complicações , Sequestro Broncopulmonar/diagnóstico por imagem , Sequestro Broncopulmonar/cirurgia , Diagnóstico Diferencial , Feminino , Comunicação Interatrial/complicações , Comunicação Interatrial/diagnóstico por imagem , Comunicação Interatrial/cirurgia , Humanos , Imagem por Ressonância Magnética , Neoplasias do Mediastino/complicações , Neoplasias do Mediastino/diagnóstico por imagem , Neoplasias do Mediastino/cirurgia , Teratoma/complicações , Teratoma/diagnóstico por imagem , Teratoma/cirurgia , Cirurgia Torácica Vídeoassistida , Tomografia Computadorizada por Raios X , Adulto Jovem
11.
J Obstet Gynaecol Res ; 45(9): 1957-1960, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31215124

RESUMO

We present a case of malignant change of an ovarian mature cystic teratoma. Our patient was a 48-year-old woman and she visited a primary care doctor presenting with abdominal pain. At her first visit, her pelvic tumor measured 70 × 50 mm by ultrasonography. She was diagnosed as rupture of the malignant tumor occurred secondary to mature cystic teratoma and she took the surgery (abdominal total hysterectomy, bilateral oophorectomy and partial omentectomy). Pathologic diagnosis was squamous cell carcinoma (SCC) occurred secondary to mature cystic teratoma. Treatment with paclitaxel/carboplatin (TC chemotherapy) and gemcitabine hydrochloride/carboplatin (GC chemotherapy) after operation was not effective, and the refractory ileus resulting from rapid progression of the disease continued. She was died of disease progression 7 months after the diagnosis of ovarian cancer. We discuss about the clinical characteristics of malignant transformation of mature cystic teratoma and considered about the treatment of the ovarian SCC.


Assuntos
Carcinoma de Células Escamosas/etiologia , Transformação Celular Neoplásica/patologia , Cistos Ovarianos/complicações , Neoplasias Ovarianas/etiologia , Teratoma/complicações , Feminino , Humanos , Pessoa de Meia-Idade , Cistos Ovarianos/patologia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/patologia , Ovário/patologia , Teratoma/patologia
12.
J Pak Med Assoc ; 69(6): 902-904, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31201402

RESUMO

We report a case of a 28 year old female who presented to us in November 2016 with a swelling in front of neck for three years and worsening shortness of breath for last one year, causing right sided tracheal deviation and mildSuperior Vena Caval obstruction. X-ray showed a soft tissue density mass in antero-superior mediastinum with cephalad extension. Contrast enhanced CT neck and chest revealed a multi cystic lesion extending from the root of neck to anterior mediastinum causing compression and deviation of trachea, and nearby structures especially Superior Vena Cava (SVC) along with collateral formation. Mass was surgically excised from the neck and mediastinum with uneventful post-operative recovery. Histopathology was consistent with benign mature cystic teratoma.


Assuntos
Neoplasias do Mediastino/diagnóstico por imagem , Teratoma/diagnóstico por imagem , Adulto , Dispneia/etiologia , Feminino , Humanos , Neoplasias do Mediastino/complicações , Neoplasias do Mediastino/patologia , Neoplasias do Mediastino/cirurgia , Pescoço , Invasividade Neoplásica , Síndrome da Veia Cava Superior/etiologia , Teratoma/complicações , Teratoma/patologia , Teratoma/cirurgia , Tomografia Computadorizada por Raios X
13.
Taiwan J Obstet Gynecol ; 58(3): 313-317, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31122515

RESUMO

OBJECTIVE: Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is a paraneoplastic syndrome associated with ovarian teratomas. Anti-NMDAR encephalitis patients typically present with prominent psychiatric symptoms, seizures, and involuntary movements; further, they rapidly progress to unresponsiveness with central hypoventilation and dysautonomia. CASE REPORT: This paper presents two anti-NMDAR encephalitis cases with ovarian teratomas and reviews 13 anti-NMDAR encephalitis clinical case reports in Taiwan, of which six involved ovarian tumors, five being mature teratomas. Patients presented with acute onset of psychiatric symptoms and subsequently developed coma within a few days. Anti-NMDAR encephalitis usually occurs in young women and is often associated with ovarian tumors, specifically teratomas. Ovarian cystectomy or oophorectomy was performed, which markedly improved cognitive function. CONCLUSION: Paraneoplastic neurological conditions associated with ovarian teratomas represent a fascinating disease process. Identifying the gynecological cause of a neurological condition, particularly in young women, followed by prompt treatment can remarkably improve clinical conditions and, thus, be lifesaving.


Assuntos
Encefalite Antirreceptor de N-Metil-D-Aspartato/etiologia , Neoplasias Ovarianas/complicações , Teratoma/complicações , Adulto , Encefalite Antirreceptor de N-Metil-D-Aspartato/tratamento farmacológico , Encefalite Antirreceptor de N-Metil-D-Aspartato/fisiopatologia , Feminino , Humanos , Imunoglobulinas/uso terapêutico , Neoplasias Ovarianas/diagnóstico por imagem , Neoplasias Ovarianas/patologia , Neoplasias Ovarianas/cirurgia , Taiwan , Teratoma/diagnóstico por imagem , Teratoma/patologia , Teratoma/cirurgia , Tomografia Computadorizada por Raios X
14.
J Cardiothorac Surg ; 14(1): 96, 2019 May 22.
Artigo em Inglês | MEDLINE | ID: mdl-31118058

RESUMO

BACKGROUND: This case highlights the challenges of preoperative differential diagnosis and management in a patient with an uncommon clinical presentation of giant intrathoracic teratoma. The age of the patient, location and size of the tumor, and clinical presentation makes this case unique. Typically, intrathoracic teratomas are found between the ages of 20-30, they are located in the anterior mediastinum, and tumors larger than 25 cm clinically present with cough or dysphagia. CASE PRESENTATION: A giant intrathoracic teratoma presents in a 51-year-old female as a mid to posterior mediastinal mass compressing the whole left lung with symptoms of depression, anorexia, unintentional weight loss, and cachexia. Due to her severe deconditioning she was optimized for 1 month in a skilled nursing facility with aggressive physical therapy and enteral nutrition. She underwent left thoracotomy with complete resection of the tumor. In follow up her BMI had improved, and she was regaining strength. CONCLUSIONS: Complete resection was achieved via left thoracotomy after aggressive rehabilitation.


Assuntos
Neoplasias do Mediastino/diagnóstico , Teratoma/diagnóstico , Caquexia/etiologia , Diagnóstico Diferencial , Dispneia/etiologia , Feminino , Humanos , Neoplasias do Mediastino/complicações , Neoplasias do Mediastino/diagnóstico por imagem , Neoplasias do Mediastino/cirurgia , Pessoa de Meia-Idade , Teratoma/complicações , Teratoma/diagnóstico por imagem , Teratoma/cirurgia , Toracotomia
15.
J Nepal Health Res Counc ; 17(1): 128-130, 2019 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-31110394

RESUMO

Lymphangiomas are slow-growing tumors that remain asymptomatic for a long time, with the tumor being identified incidentally during histopathological examination after excision. Mature cystic teratoma is benign tumor consisting of mature tissue derived from two or three germ layers. We have 47-year-old woman who underwent total abdominal hysterectomy for right adnexal mass. As her ultrasound report revealed a right adnexal mass with solid and cystic components. The histological analysis along with immunohistochemistry (D2-40) maker confirmed the diagnosis of lymphangioma of the ovary coexisting with mature cystic teratoma. There is paucity of reported case of co-existing these two tumors in same tissue. Keywords: D2-40; lymphangioma; mature cystic teratoma; ovary.


Assuntos
Linfangioma/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Neoplasias Ovarianas/diagnóstico , Teratoma/diagnóstico , Feminino , Humanos , Histerectomia , Linfangioma/complicações , Linfangioma/patologia , Linfangioma/cirurgia , Pessoa de Meia-Idade , Neoplasias Primárias Múltiplas/patologia , Neoplasias Primárias Múltiplas/cirurgia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/patologia , Neoplasias Ovarianas/cirurgia , Ovário/patologia , Salpingo-Ooforectomia , Teratoma/complicações , Teratoma/patologia , Teratoma/cirurgia
16.
Pediatr Blood Cancer ; 66(8): e27788, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31038288

RESUMO

Growing teratoma syndrome (GTS) is a condition in which mature teratoma with negative tumor markers arises at the site of a treated malignant germ cell tumor. Pathogenic variants in PTEN have been reported to cause autosomal dominant cancer predisposition syndromes and are associated with germ cell tumors. We report the association of a novel heterozygous pathogenic variant in PTEN and very early onset ovarian germ cell tumor complicated by GTS as well as overgrowth syndrome. This marks the youngest reported patient to have developed GTS following treatment of her primary malignant ovarian germ cell tumor.


Assuntos
Heterozigoto , Mutação , Neoplasias Embrionárias de Células Germinativas/patologia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/patologia , PTEN Fosfo-Hidrolase/genética , Teratoma/complicações , Pré-Escolar , Feminino , Humanos , Neoplasias Embrionárias de Células Germinativas/etiologia , Neoplasias Embrionárias de Células Germinativas/genética , Neoplasias Ovarianas/etiologia , Neoplasias Ovarianas/genética , Prognóstico , Síndrome , Teratoma/genética
18.
World Neurosurg ; 128: e334-e339, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31028986

RESUMO

BACKGROUND: The cerebellomesencephalic vein (CMV) was frequently sacrificed in surgery approached via the supracerebellar infratentorial (SCIT) route for resecting pineal region tumors, which resulted in potential risk of neurologic deficit. Preserving the CMV in the SCIT approach could enhance the safety and effectiveness of this natural corridor surgery. The aim of this article was to identify the probability and safety of preserving the CMV through the application of neuroendoscopy in the SCIT approach. METHODS: Clinical data of patients who underwent pineal region tumor resection through a purely endoscopic SCIT approach were retrospectively analyzed, focusing on surgical techniques and clinical outcomes. RESULTS: The study included 8 patients with pineal region tumors. The CMV was preserved intact in all patients. Total tumor removal was achieved in 7 of 8 patients. In 1 patient with 2 tumors in the pineal region and roof of the third ventricle, the tumor in the pineal region was resected completely, followed by subsequent chemotherapy combined with radiotherapy, after which the other tumor disappeared totally. All patients recovered normally with uneventful postoperative outcomes. CONCLUSIONS: The advantage of close observation and panoramic view provided by neuroendoscopy combined with meticulous manipulation improved the ability to preserve the CMV in resecting pineal region tumors via the SCIT approach. The neuroendoscopic technique enhances the safety and efficacy of the SCIT approach.


Assuntos
Neoplasias Encefálicas/cirurgia , Neuroendoscopia/métodos , Glândula Pineal/cirurgia , Pinealoma/cirurgia , Terceiro Ventrículo/cirurgia , Adulto , Neoplasias Encefálicas/complicações , Cerebelo/irrigação sanguínea , Criança , Germinoma/complicações , Germinoma/cirurgia , Glioblastoma/complicações , Glioblastoma/cirurgia , Cefaleia/etiologia , Humanos , Masculino , Mesencéfalo/irrigação sanguínea , Pessoa de Meia-Idade , Neurocitoma/complicações , Neurocitoma/cirurgia , Tratamentos com Preservação do Órgão , Pinealoma/complicações , Estudos Retrospectivos , Teratoma/complicações , Teratoma/cirurgia , Ventriculostomia , Adulto Jovem
19.
Mult Scler Relat Disord ; 31: 97-100, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30954932

RESUMO

Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory disease of the central nervous system, characterized by the presence of auto-antibodies directed against aquaporin-4 (AQP4) expressed on astrocyte end-feet. Despite NMOSD does not primarily belong to the spectrum of paraneoplastic neurological syndromes, rare cases of association with neoplasia have been outlined. Here, we report the association of NMOSD with ovarian teratoma in 3 cases. Pathological analysis of teratomas revealed glial component strongly expressing AQP4 and closely localized to immune infiltrates. Our series highlight the rare association of teratoma with NMOSD and the possible paraneoplastic mechanism.


Assuntos
Neuromielite Óptica/complicações , Neuromielite Óptica/patologia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/patologia , Teratoma/complicações , Teratoma/patologia , Adolescente , Adulto , Aquaporina 4/metabolismo , Feminino , Humanos , Neuromielite Óptica/diagnóstico , Neuromielite Óptica/metabolismo , Neoplasias Ovarianas/diagnóstico , Neoplasias Ovarianas/metabolismo , Teratoma/diagnóstico , Teratoma/metabolismo , Adulto Jovem
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