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1.
Sensors (Basel) ; 21(5)2021 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-33800920

RESUMO

There is a need for continuous, non-invasive monitoring of biological data to assess health and wellbeing. Currently, many types of smart patches have been developed to continuously monitor body temperature, but few trials have been completed to evaluate psychometrics and feasibility for human subjects in real-life scenarios. The aim of this feasibility study was to evaluate the reliability, validity and usability of a smart patch measuring body temperature in healthy adults. The smart patch consisted of a fully integrated wearable wireless sensor with a multichannel temperature sensor, signal processing integrated circuit, wireless communication feature and a flexible battery. Thirty-five healthy adults were recruited for this test, carried out by wearing the patches on their upper chests for 24 h and checking their body temperature six times a day using infrared forehead thermometers as a gold standard for testing validity. Descriptive statistics, one-sampled and independent t-tests, Pearson's correlation coefficients and Bland-Altman plot were examined for body temperatures between two measures. In addition, multiple linear regression, receiver operating characteristic (ROC) and qualitative content analysis were conducted. Among the 35 participants, 29 of them wore the patch for over 19 h (dropout rate: 17.14%). Mean body temperature measured by infrared forehead thermometers and smart patch ranged between 32.53 and 38.2 °C per person and were moderately correlated (r = 0.23-0.43) overall. Based on a Bland-Altman plot, approximately 94% of the measurements were located within one standard deviation (upper limit = 4.52, lower limit = -5.82). Most outliers were identified on the first measurement and were located below the lower limit. It is appropriate to use 37.5 °C in infrared forehead temperature as a cutoff to define febrile conditions. Users' position while checking and ambient temperature and humidity are not affected to the smart patch body temperature. Overall, the participants showed high usability and satisfaction on the survey. Few participants reported discomfort due to limited daily activity, itchy skin or detaching concerns. In conclusion, epidermal electronic sensor technologies provide a promising method for continuously monitoring individuals' body temperatures, even in real-life situations. Our study findings show the potential for smart patches to monitoring non-febrile condition in the community.


Assuntos
Temperatura Cutânea , Termômetros , Adulto , Temperatura Corporal , Estudos de Viabilidade , Humanos , Psicometria , Reprodutibilidade dos Testes
2.
Sensors (Basel) ; 21(5)2021 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-33669012

RESUMO

In this paper, the key technology of interferometric microwave thermometer is studied, the research can be applied to the temperature measurement of human body and subcutaneous tissue. This paper proposes a hardware architecture of interferometric microwave thermometer with 2 GHz bandwidth, in which the phase shifter is used to correct phase error and the quadrature demodulator is used to realize autocorrelation detection function. The results show that when input power is 7 dBm, the detection sensitivity can reach 176.54 mV/dBm and the temperature resolution of the microwave radiometer can reach 0.4 K. Correction algorithm is designed to improve the accuracy of temperature measurement. After correction, the phase error is reduced from 40° to 1.4° and when temperature changes 0.1 °C, the voltage value changes obviously. Step-by-step calibration and overall calibration are used to calibrate the device. Inversion algorithm can determine the relationship between physical temperature and output voltage. The mean square error of water temperature inversion by multiple linear regression algorithm is 0.607 and that of BP neural network algorithm is 0.334. The inversion accuracy can be improved by reducing the temperature range. Our work provides a promising realization of accurate, rapid and non-contact detection device of human body temperature.


Assuntos
Temperatura Corporal , Micro-Ondas , Humanos , Radiometria , Temperatura , Termômetros
3.
Br J Nurs ; 30(5): 288-295, 2021 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-33733857

RESUMO

This article explores body temperature and the physiological process of thermoregulation. Normal body temperature and body temperature changes are discussed, including comorbidities associated with body temperature and signs of hyperthermia and hypothermia, and the factors that affect intraoperative temperature regulation. The evidence base behind thermometry is discussed and is applied to contemporary clinical conditions and symptoms, including: sepsis and suspected COVID-19. After discussing clinical considerations and regulations that encompass thermometry, three case studies present the use of the Genius 3 Tympanic Thermometer in clinical practice, with user feedback supporting its benefits, which include speed, accuracy and ease of use.


Assuntos
Temperatura Corporal/fisiologia , Termômetros , Membrana Timpânica/fisiologia , /diagnóstico , Terapias Complementares , Cuidados Críticos , Humanos , Monitorização Fisiológica/instrumentação , Reprodutibilidade dos Testes , Sepse/diagnóstico , Fatores de Tempo
5.
Food Chem ; 351: 129292, 2021 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-33626465

RESUMO

The detection of carbendazim (CBZ) is important for food safety and human health. However, most current analytical methods require large instruments and highly trained operators. In order to solve this problem, herein, an innovative portable and quantitative photothermal assay platform relying on a thermometer readout for the detection of CBZ has been developed. Gold nanoparticles (AuNPs), which exhibit a strong distance-dependent photothermal effect under specific laser irradiation, were utilized as indicators. The CBZ aptamer was introduced to protect AuNPs from salt-mediated aggregation. When CBZ is present, the binding event between CBZ and aptamer leads to the loss of the aptamer protective effect on AuNPs, and AuNP aggregation occurs. Under 650-nm laser irradiation, the increase in temperature associated with an AuNP-dependent photothermal effect is highly related to the CBZ concentration. Having the advantages of user-friendliness, low cost, quick response, and portability, this method has great potential for on-site applications.


Assuntos
Benzimidazóis/análise , Carbamatos/análise , Análise de Alimentos/métodos , Fungicidas Industriais/análise , Aptâmeros de Nucleotídeos/química , Aptâmeros de Nucleotídeos/metabolismo , Brassica/química , Brassica/metabolismo , Citrus/química , Citrus/metabolismo , Análise de Alimentos/instrumentação , Frutas/química , Frutas/metabolismo , Ouro/química , Nanopartículas Metálicas/química , Espectrofotometria Ultravioleta , Temperatura , Termômetros
6.
J Perinat Med ; 49(3): 255-261, 2021 Mar 26.
Artigo em Inglês | MEDLINE | ID: mdl-33554570

RESUMO

OBJECTIVES: Fever is the single most frequently reported manifestation of COVID-19 and is a critical element of screening persons for COVID-19. The meaning of "fever" varies depending on the cutoff temperature used, the type of thermometer, the time of the day, the site of measurements, and the person's gender and race. The absence of a universally accepted definition for fever has been especially problematic during the current COVID-19 pandemic. METHODS: This investigation determined the extent to which fever is defined in COVID-19 publications, with special attention to those associated with pregnancy. RESULTS: Of 53 publications identified in which "fever" is reported as a manifestation of COVID-19 illness, none described the method used to measure patient's temperatures. Only 10 (19%) publications specified the minimum temperature used to define a fever with values that varied from a 37.3 °C (99.1 °F) to 38.1 °C (100.6 °F). CONCLUSIONS: There is a disturbing lack of precision in defining fever in COVID-19 publications. Given the many factors influencing temperature measurements in humans, there can never be a single, universally accepted temperature cut-off defining a fever. This clinical reality should not prevent precision in reporting fever. To achieve the precision and improve scientific and clinical communication, when fever is reported in clinical investigations, at a minimum the cut-off temperature used in determining the presence of fever, the anatomical site at which temperatures are taken, and the instrument used to measure temperatures should each be described. In the absence of such information, what is meant by the term "fever" is uncertain.


Assuntos
/métodos , Confiabilidade dos Dados , Febre/diagnóstico , Publicações Periódicas como Assunto , Projetos de Pesquisa/normas , Termometria/normas , /complicações , /normas , Feminino , Febre/virologia , Humanos , Gravidez , Complicações Infecciosas na Gravidez/diagnóstico , Padrões de Referência , Projetos de Pesquisa/estatística & dados numéricos , Termômetros , Termometria/instrumentação , Termometria/métodos
7.
J Med Eng Technol ; 45(2): 136-144, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33632055

RESUMO

There has been a marked rise in the number of avoidable deaths in health services around the world. At the same time there has been a growing increase in antibiotic resistant so-called "superbugs." We examine here the potential role of body temperature measurement in these adverse trends. Electronic based thermometers have replaced traditional mercury (and other liquid-in-glass type) thermometers for reasons of safety rather than superiority. Electronic thermometers are in general less robust from a measurement perspective than their predecessors. We illustrate the implications of unreliable temperature measurement on the diagnosis and management of disease, including COVID-19, through statistical calculations. Since a return to mercury thermometers is both undesirable and impractical, we call for better governance in the current practice of clinical thermometry to ensure the traceability and long-term accuracy of electronic thermometers and discuss how this could be achieved.


Assuntos
Temperatura Corporal/fisiologia , Termometria/métodos , /diagnóstico , Humanos , Guias de Prática Clínica como Assunto , Termômetros/efeitos adversos , Termômetros/normas , Termometria/efeitos adversos , Termometria/instrumentação , Termometria/normas , Incerteza
8.
Chemistry ; 27(21): 6479-6488, 2021 Apr 12.
Artigo em Inglês | MEDLINE | ID: mdl-33476058

RESUMO

In recent years, luminescent materials doped with Ln3+ ions have attracted much attention for their application as optical thermometers based on both downshifting and upconversion processes. This study presents research done on the development of highly sensitive optical thermometers in the physiological temperature range based on poly(methyl methacrylate) (PMMA) films doped with two series of visible Ln3+ complexes (Ln3+ =Tb3+ , Eu3+ , and Sm3+ ) and SiO2 nanoparticles (NPs) coated with these PMMA films. The best performing PMMA film doped with Tb3+ and Eu3+ complexes was the PMMA[TbEuL1 tppo]1 film (L1 =4,4,4-trifluoro-1-phenyl-1,3-butadionate; tppo=triphenylphosphine oxide), which showed good temperature sensing of Sr =4.21 % K-1 at 313 K, whereas for the PMMA films doped with Tb3+ and Sm3+ complexes the best performing was the PMMA[TbSmL2 tppo]3 film (L2 =4,4,4-trifluoro-1-(4-chlorophenyl)-1,3-butadionate), with Sr =3.64 % K-1 at 313 K. Additionally, SiO2 NPs coated with the best performing films from each of the series of PMMA films (Tb-Eu and Tb-Sm) and their temperature-sensing properties were studied in water, showing excellent performance in the physiological temperature range (PMMA[TbEuL1 tppo]1@SiO2 : Sr =3.84 % °C at 20 °C; PMMA[TbSmL2 tppo]3@SiO2 : Sr =3.27 % °C at 20 °C) and the toxicity of these nanoparticles on human cells was studied, showing that they were nontoxic.


Assuntos
Nanopartículas , Polimetil Metacrilato , Humanos , Dióxido de Silício , Temperatura , Termômetros
9.
ACS Appl Mater Interfaces ; 13(1): 1353-1366, 2021 Jan 13.
Artigo em Inglês | MEDLINE | ID: mdl-33351585

RESUMO

Stimulus-responsive hydrogels, such as conductive hydrogels and thermoresponsive hydrogels, have been explored extensively and are considered promising candidates for smart materials such as wearable devices and artificial muscles. However, most of the existing studies on stimulus-responsive hydrogels have mainly focused on their single stimulus-responsive property and have not explored multistimulus-responsive or multifunction properties. Although some works involved multifunctionality, the prepared hydrogels were incompatible. In this work, a multistimulus-responsive and multifunctional hydrogel system (carboxymethyl cellulose/poly acrylic-acrylamide) with good elasticity, superior flexibility, and stable conductivity was prepared. The prepared hydrogel not only showed excellent human motion detection and physiological signal response but also possessed the ability to respond to environmental temperature changes. By integrating a conductive hydrogel with a thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) hydrogel to form a bilayer hydrogel, the prepared bilayer also functioned as two kinds of actuators owing to the different degrees of swelling and shrinking under different thermal stimuli. Furthermore, the different thermochromic properties of each layer in the bilayer hydrogel endowed the hydrogel with a thermoresponsive "smart" feature, the ability to display and conceal information. Therefore, the prepared hydrogel system has excellent prospects as a smart material in different applications, such as ionic skin, smart info-window, and soft robotics.


Assuntos
Carboximetilcelulose Sódica/química , Hidrogéis/química , Monitorização Fisiológica/instrumentação , Dispositivos Eletrônicos Vestíveis , Resinas Acrílicas/química , Alumínio/química , Elasticidade , Condutividade Elétrica , Humanos , Movimento , Temperatura , Termômetros
10.
Biosens Bioelectron ; 171: 112676, 2021 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-33049564

RESUMO

Herein, a facile thermometer-like model of electrophoresis titration (ET) biosensor was proposed as an alternative tool for miRNA assay via moving reaction boundary (MRB) chip. For proof-of-concept demonstration, miRNA-122 and catalyzed hairpin assembly (CHA) were chosen as the model analyte and amplification, respectively. In the developed ET system, miRNA triggered the CHA with two hairpin probes (H1, H2) to yield H1-H2 duplexes with negative charges. Under an electric field, the duplexes moved into ET channel, and neutralized the acidic TAE buffer creating an MRB indicated by SYBR Green I (SGI). The model revealed that the MRB distance was as a function of logarithmic miRNA-122 content, indicating a facile sensing model. The relevant experiments were conducted and systemically validated the model of miRNA ET. Under the optimized conditions, the linear range of ET sensor was from 20 fM to 1 nM and the limit of detection (LOD) was 10 fM, showing a more than 100-fold sensitive increase in contrast to the one with a single CHA amplification. The mechanism of sensitive increase was well unveiled by the designed experiments. In addition, the ET biosensor had good selectivity, stability (less than 5% for intra-day and inter-day) and recovery (96%-110%), and was successfully applied for the assay of miRNA-122 and miRNA let-7a in real bio-fluids of serum and cancer cell lysate. Evidently, the proposed biosensor might be used as an alternative assay tool after nucleic acid amplification due to its high simplicity, sensitivity, specificity, linearity, stability and recovery.


Assuntos
Técnicas Biossensoriais , MicroRNAs , Eletroforese , Limite de Detecção , MicroRNAs/análise , Termômetros
11.
Ann Agric Environ Med ; 27(4): 689-694, 2020 Dec 22.
Artigo em Inglês | MEDLINE | ID: mdl-33356079

RESUMO

INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is a condition that affects over 2 million adults in Poland. In recent years, increasing attention has been focused on improving the quality of life of patients with COPD, which includes alleviating their physical discomfort and relates to their mental health. It is therefore critically important to evaluate research tools that can accurately assess the relationship between the physical and mental health of patients with this disease. OBJECTIVE: This aim of the study is to evaluate the relationship between the COPD Assessment Test (CAT) and the Distress Thermometer and Problem List results in COPD patients. MATERIAL AND METHODS: The research evaluated 70 patients with COPD as defined by the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) criteria. Demographic data was obtained at baseline. Disease-specific quality of life was assessed using the CAT score, while overall distress was determined using the Distress Thermometer (DT) scale and a modified Problem List. The relationship between the CAT scores and the results of the Distress Thermometer and Problem List was statistically compared. The study was approved by the Bioethics Committee, and all patients provided written informed consent. RESULTS: The mean ± SD age was 69.6±9.05 (range 47-90) years. The average distress level was 4.09±1.95. A significant relationship was established between the CAT score and the results of the Distress Thermometer Scale (p<0.001); patients with higher CAT scores showed the highest level of distress. CONCLUSIONS: CAT was shown to be a simple, fast and clear measurement of disease-specific quality of life and was correlated with levels of distress in patients with COPD. Every patient with COPD should be evaluated using a scale such as the DT to measure their level of psychological distress.


Assuntos
Doença Pulmonar Obstrutiva Crônica/psicologia , Qualidade de Vida/psicologia , Termômetros/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Polônia , Doença Pulmonar Obstrutiva Crônica/etiologia
13.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 4377-4380, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018965

RESUMO

We describe the design of a thermometer that can be worn during everyday activities for monitoring core body temperature (CBT) at the skin surface. This sensor estimates the CBT by measuring the heat flux from the body core based on a thermal conductive model. The heat flux is usually affected by the ambient convective conditions (e.g. air conditioner or posture), which in turn affects the model's accuracy. Thus, we analytically investigated heat conduction and designed a sensor interface that would be robust to convection changes. We performed an in vitro experiment and a preliminary in vivo experiment. The accuracy of CBT in an in vitro experiments was 0.1°C for convective values ranging from 0 to 1.2 m/s. The wearable thermometer has high potential as non-invasive CBT monitor.


Assuntos
Termômetros , Dispositivos Eletrônicos Vestíveis , Temperatura Corporal , Temperatura Alta , Monitorização Fisiológica
14.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 5831-5837, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33019300

RESUMO

Clinicians often use speech to characterize neurodegenerative disorders. Such characterizations require clinical judgment, which is subjective and can require extensive training. Quantitative Production Analysis (QPA) can be used to obtain objective quantifiable assessments of patient functioning. However, such human-based analyses of speech are costly and time consuming. Inexpensive off-the-shelf technologies such as speech recognition and part of speech taggers may avoid these problems. This study evaluates the ability of an automatic speech to text transcription system and a part of speech tagger to assist with measuring pronoun and verb ratios, measures based on QPA. Five participant groups provided spontaneous speech samples. One group consisted of healthy controls, while the remaining groups represented four subtypes of frontotemporal dementia. Findings indicated measurement of pronoun and verb ratio was robust despite errors introduced by automatic transcription and the tagger and despite these off-the-shelf products not having been trained on the language obtained from speech of the included population.


Assuntos
Demência Frontotemporal , Doenças Neurodegenerativas , Doença de Pick , Demência Frontotemporal/diagnóstico , Humanos , Doenças Neurodegenerativas/diagnóstico , Fala , Termômetros
15.
Rev. Rol enferm ; 43(9): 620-628, sept. 2020. ilus, tab, graf
Artigo em Espanhol | IBECS | ID: ibc-194391

RESUMO

FUNDAMENTOS: La pandemia por COVID-19 ha alcanzado más de cinco millones de contagios y trescientos mil fallecidos en el mundo. Todos ellos precisan la evaluación de factores pronósticos; además de la edad avanzada, las comorbilidades o la respuesta inflamatoria, es también evidente la necesidad de evaluar la temperatura corporal para determinar el contagio, la exposición, especialmente en personas con diferentes factores de riesgo, y distintos patrones evolutivos para conocer su influencia sobre los desenlaces clínicos. MÉTODOS: Se realizó un estudio transversal de tomas de temperatura a 42 sujetos voluntarios, para valorar la fiabilidad en términos de concordancia entre dos termómetros utilizados en las tomas de temperatura corporal; se compararon las mediciones de 2 termómetros en las zonas frontal y oído en 2 salas (mayor y menor iluminación). Se compararon los intervalos de confianza y se calculó el coeficiente de Correlación Intraclase (CCI) para obtener las diferencias estadísticas, proporcionando unos límites de concordancia a partir del cálculo del intervalo de confianza para la diferencia de dos mediciones. RESULTADOS: Con un intervalo de confianza del 95 %, una p < 0,5 y en las condiciones medidas, y sobre la muestra de sujetos, observamos que la correlación de las mediciones no tiene diferencia estadística significativa, pero sí en los diferentes ambientes con mayor iluminación. CONCLUSIONES: La media de temperatura corporal (frontal) medida con el termómetro láser es mayor que la temperatura (frontal) medida con el termómetro Testo. Existe diferencia significativa en las mediciones realizadas en las 2 salas, siendo mayores en la sala con menor iluminación. Hay correlación en las mediciones de temperatura del mismo instrumento en la zona frontal y en oído. Los termómetros láser son más efectivos para detectar las variaciones en la temperatura corporal, y más asertivos para identificar uno de los síntomas más asociados a la infección por SARS-CoV-2


BACKGROUND: The COVID-19 pandemic has reached more than five million infections and three hundred thousand deaths worldwide, all of which require the assessment of prognostic factors; in addition to advanced age, comorbidities or the inflammatory response, is also evident the need to assess body temperature to determine contagion, exposure, especially in people with different risk factors, and different evolutionary patterns to know its influence on clinical outcomes. METHODS: A cross-sectional study of temperature measurements was performed on 42 volunteer subjects, to assess the reliability in terms of agreement between two thermometers used in body temperature measurements; the measurements of 2 thermometers in the frontal and ear areas were compared in 2 rooms (higher and lower lighting). Confidence intervals were compared and the Intraclass Correlation Coefficient (ICC) was calculated to obtain the statistical differences, providing limits of agreement from the calculation of the confidence interval for the difference of two measurements. RESULTS: With a 95 % confidence interval, a p <0.5 and under the measured conditions, and on our sample of subjects, we observe that the correlation of the measurements does not have significant statistical difference, but indeed in different environments with greater lighting. CONCLUSIONS: The average body temperature (front) measured with the laser thermometer is greater than the temperature (front) measured with the Testo thermometer. There is a significant difference in the measurements made in the 2 rooms, being greater in the room with less lighting. There is correlation in the temperature measurements of the same instrument in the frontal zone and in the ear. Laser thermometers are more effective in detecting variations in body temperature, and more assertive in identifying one of the symptoms most associated with SARS-CoV-2 infection


Assuntos
Humanos , Infecções por Coronavirus/epidemiologia , Temperatura Corporal , Febre/diagnóstico , Termômetros/estatística & dados numéricos , Termometria/estatística & dados numéricos , Estudos Transversais , Controle de Doenças Transmissíveis/métodos , Reprodutibilidade dos Testes
16.
J Am Med Dir Assoc ; 21(7): 895-899.e1, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32674815

RESUMO

OBJECTIVES: Many nursing home residents infected with SARS-CoV-2 fail to be identified with standard screening for the associated COVID-19 syndrome. Current nursing home COVID-19 screening guidance includes assessment for fever, defined as a temperature of at least 38.0°C. The objective of this study was to describe the temperature changes before and after universal testing for SARS-CoV-2 in nursing home residents. DESIGN: Cohort study. SETTING AND PARTICIPANTS: The Veterans Administration (VA) operates 134 Community Living Centers (CLC), similar to nursing homes, that house residents who cannot live independently. VA guidance to CLCs directed daily clinical screening for COVID-19 that included temperature assessment. MEASURES: All CLC residents (n = 7325) underwent SARS-CoV-2 testing. We report the temperature in the window of 14 days before and after universal SARS-CoV-2 testing among CLC residents. Baseline temperature was calculated for 5 days before the study window. RESULTS: SARS-CoV-2 was identified in 443 (6.0%) residents. The average maximum temperature in SARS-CoV-2-positive residents was 37.66 (0.69) compared with 37.11 (0.36) (P = .001) in SARS-CoV-2-negative residents. Temperatures in those with SARS-CoV-2 began rising 7 days before testing and remained elevated during the 14-day follow-up. Among SARS-CoV-2-positive residents, only 26.6% (n = 118) met the fever threshold of 38.0°C during the survey period. Most residents (62.5%, n = 277) with confirmed SARS-CoV-2 did experience 2 or more 0.5°C elevations above their baseline values. One cohort of SARS-CoV-2 residents' (20.3%, n = 90) temperatures never deviated >0.5°C from baseline. CONCLUSIONS AND IMPLICATIONS: A single screening for temperature is unlikely to detect nursing home residents with SARS-CoV-2. Repeated temperature measurement with a patient-derived baseline can increase sensitivity. The current fever threshold as a screening criteria for SARS-CoV-2 infection should be reconsidered.


Assuntos
Infecções por Coronavirus/diagnóstico , Febre/diagnóstico , Programas de Rastreamento/métodos , Casas de Saúde/organização & administração , Pneumonia Viral/diagnóstico , Instituições de Cuidados Especializados de Enfermagem/organização & administração , Idoso , Idoso de 80 Anos ou mais , Temperatura Corporal/fisiologia , Técnicas de Laboratório Clínico/métodos , Estudos de Coortes , Infecções por Coronavirus/prevenção & controle , Surtos de Doenças/prevenção & controle , Diagnóstico Precoce , Feminino , Febre/epidemiologia , Humanos , Controle de Infecções , Masculino , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Termômetros/estatística & dados numéricos , Estados Unidos , Veteranos
17.
J Gen Physiol ; 152(8)2020 08 03.
Artigo em Inglês | MEDLINE | ID: mdl-32531043
19.
Sensors (Basel) ; 20(10)2020 May 19.
Artigo em Inglês | MEDLINE | ID: mdl-32438729

RESUMO

Many types of thermometers have been developed to measure body temperature. Infrared thermometers (IRT) are fast, convenient and ease to use. Two types of infrared thermometers are uses to measure body temperature: tympanic and forehead. With the spread of COVID-19 coronavirus, forehead temperature measurement is used widely to screen people for the illness. The performance of this type of device and the criteria for screening are worth studying. This study evaluated the performance of two types of tympanic infrared thermometers and an industrial infrared thermometer. The results showed that these infrared thermometers provide good precision. A fixed offset between tympanic and forehead temperature were found. The measurement values for wrist temperature show significant offsets with the tympanic temperature and cannot be used to screen fevers. The standard operating procedure (SOP) for the measurement of body temperature using an infrared thermometer was proposed. The suggestion threshold for the forehead temperature is 36 °C for screening of fever. The body temperature of a person who is possibly ill is then measured using a tympanic infrared thermometer for the purpose of a double check.


Assuntos
Temperatura Corporal/fisiologia , Infecções por Coronavirus/diagnóstico , Febre/diagnóstico , Pneumonia Viral/diagnóstico , Termômetros , Infecções por Coronavirus/fisiopatologia , Infecções por Coronavirus/virologia , Febre/fisiopatologia , Febre/virologia , Testa/fisiopatologia , Humanos , Raios Infravermelhos , Pandemias , Pneumonia Viral/fisiopatologia , Pneumonia Viral/virologia
20.
Nanoscale Horiz ; 5(3): 488-494, 2020 03 02.
Artigo em Inglês | MEDLINE | ID: mdl-32118250

RESUMO

We designed and synthesized a novel nano-thermometer using aggregation-induced-emission (AIE) dye as the reporter and household butter as the matrix. This temperature nanosensor showed decreased fluorescence intensities (∼2%/°C) and shorter fluorescence lifetimes (∼0.11 ns/°C) upon increasing the environmental temperature in the physiological temperature range. Such fluorescence responses were reversible and independent of the environmental pH and ionic strength. The application of these nano-thermometers in temperature sensing in living cells using fluorescence lifetime imaging microscopy (FLIM) was also demonstrated. To the best of our knowledge, this is the first example of AIE-based nano-thermometer for temperature sensing in living cells. This work also provides us with a simple and low-cost method for rapid fabrication of an effective nanosensor based on AIE mechanism.


Assuntos
Fenômenos Fisiológicos Celulares , Microscopia de Fluorescência/métodos , Nanotecnologia/métodos , Termômetros , Corantes Fluorescentes , Temperatura , Termografia
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