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1.
Vestn Otorinolaringol ; 85(4): 30-34, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32885633

RESUMO

The presence of additional disabilities (AD) in children with sensorineural hearing loss (SNHL) and influence of AD on age of hearing loss diagnosis and amplification were investigated. It was shown that 41% children with SNHL have different AD - pathology of the central neural system (including mental retardation, autism spectrum disorders, attention deficits), vision, motor and articulation impairments, cardiovascular, respiratory, urinary, digestive, endocrine diseases etc. 59% children among them have 2-3 AD. The most often combination of AD was pathology of central neural and motor systems. The genetic factor was revealed rarely in the group of children with AD than in children with SNHL only. The diagnosis of hearing loss before age 4 months was rarely in the group of children with AD. Possibly it is because of the most of such children got treatment in neonatal intensive care unit and didn't have access to universal newborn hearing screening. Moreover, SNHL might develop later as the outcome of their AD or their treatment. Suggestion about more late amplification in children with SNHL was confirmed. The cause might be wary relation of audiologists to amplification of children with AD and difficulties of this process.


Assuntos
Auxiliares de Audição , Perda Auditiva Neurossensorial , Perda Auditiva , Criança , Audição , Testes Auditivos , Humanos , Recém-Nascido
2.
Codas ; 32(4): e20190135, 2020.
Artigo em Inglês, Português | MEDLINE | ID: mdl-32813819

RESUMO

PURPOSE: To evaluate the ability that in tune and out of tune individuals have to identify normal and deviated voice qualities and to compare it with their performance in auditory processing tests and perceptual judgment. METHOD: The study investigated 15 in tune and 15 out of tune individuals. Participants were matched for age and sex, were amateur choir singers, had normal hearing thresholds and normal vocal quality. All individuals underwent Pitch-matching scanning to be classified as in or out of tune. Next, they performed the Pitch Pattern Sequence (PPS) and the Duration Pattern Sequence (DPS) tests and the perceptual judgment of 36 voices plus 20% of repetition for reliability analysis. RESULTS: The out of tune individuals had worse performance in the PPS and DPS for both ears (p=0.002 RE; p=0.001 LE; p=0.009 DPS); no difference was observed in the perceptual judgment and the reliability (p=0.153). However, participants with normal PPS and DPS had better performance in the perceptual judgment and better reliability (p=0.033). Thus, individuals with disorders in temporal auditory processing skills have greater difficulty in the perceptual judgment and have lower intra-rater reliability, despite being in or out of tune. CONCLUSION: It can be observed that voice tone is not required to guarantee good perceptual judgment. However, temporal patterns and intra-rater reliability are essential to perceptually assess normal and altered voice qualities. Therefore, auditory training should be included in programs that aim to develop voice perceptual judgment abilities.


Assuntos
Transtornos da Percepção Auditiva/fisiopatologia , Transtornos da Percepção Auditiva/psicologia , Julgamento , Acústica da Fala , Qualidade da Voz , Percepção Auditiva , Estudos de Casos e Controles , Audição , Testes Auditivos , Humanos , Reprodutibilidade dos Testes
3.
Int J Immunopathol Pharmacol ; 34: 2058738420941754, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32649262

RESUMO

Aim of this communication is to remind clinical professionals to be aware of ototoxic side effects of several specific drugs proposed for the treatment of the new virus SARS-CoV-2 (Covid-19). In particular, chloroquine and hydroxychloroquine, azithromycin, as well as antiviral drugs such as remdesivir, favipiravir and lopinavir can all present potential ototoxic side effects. The data in the literature do not offer specific information on their potential synergetic effects nor on their interactions.


Assuntos
Infecções por Coronavirus/complicações , Monitoramento de Medicamentos , Transtornos da Audição/induzido quimicamente , Transtornos da Audição/complicações , Ototoxicidade , Pneumonia Viral/complicações , Antimaláricos/efeitos adversos , Antimaláricos/uso terapêutico , Antivirais/efeitos adversos , Antivirais/uso terapêutico , Azitromicina/efeitos adversos , Azitromicina/uso terapêutico , Infecções por Coronavirus/tratamento farmacológico , Transtornos da Audição/terapia , Testes Auditivos , Humanos , Pandemias
4.
PLoS One ; 15(7): e0235782, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32649733

RESUMO

Individuals with hearing loss allocate cognitive resources to comprehend noisy speech in everyday life scenarios. Such a scenario could be when they are exposed to ongoing speech and need to sustain their attention for a rather long period of time, which requires listening effort. Two well-established physiological methods that have been found to be sensitive to identify changes in listening effort are pupillometry and electroencephalography (EEG). However, these measurements have been used mainly for momentary, evoked or episodic effort. The aim of this study was to investigate how sustained effort manifests in pupillometry and EEG, using continuous speech with varying signal-to-noise ratio (SNR). Eight hearing-aid users participated in this exploratory study and performed a continuous speech-in-noise task. The speech material consisted of 30-second continuous streams that were presented from loudspeakers to the right and left side of the listener (±30° azimuth) in the presence of 4-talker background noise (+180° azimuth). The participants were instructed to attend either to the right or left speaker and ignore the other in a randomized order with two different SNR conditions: 0 dB and -5 dB (the difference between the target and the competing talker). The effects of SNR on listening effort were explored objectively using pupillometry and EEG. The results showed larger mean pupil dilation and decreased EEG alpha power in the parietal lobe during the more effortful condition. This study demonstrates that both measures are sensitive to changes in SNR during continuous speech.


Assuntos
Auxiliares de Audição , Pupila/fisiologia , Percepção da Fala , Idoso , Idoso de 80 Anos ou mais , Percepção Auditiva , Eletroencefalografia , Feminino , Audição , Testes Auditivos , Humanos , Masculino , Pessoa de Meia-Idade , Razão Sinal-Ruído
5.
J Laryngol Otol ; 134(6): 519-525, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32613920

RESUMO

OBJECTIVE: To present our data evaluating the feasibility of simultaneous cochlear implantation with resection of acoustic neuroma. METHODS: This paper describes a case series of eight adult patients with a radiologically suspected acoustic neuroma, treated at a tertiary referral centre in Newcastle, Australia, between 2012 and 2015. Patients underwent cochlear implantation concurrently with removal of an acoustic neuroma. The approach was translabyrinthine, with facial nerve monitoring and electrically evoked auditory brainstem response testing. Standard post-implant rehabilitation was employed, with three and six months' follow-up data collected. The main outcome measures were: hearing, subjective benefit of implant, operative complications and tumour recurrence. RESULTS: Eight patients underwent simultaneous cochlear implantation with resection of acoustic neuroma over a 3-year period, and had 25-63 months' follow up. There were no major complications. All patients except one gained usable hearing and were daily implant users. CONCLUSION: Simultaneous cochlear implantation with resection of acoustic neuroma has been shown to be a safe treatment option, which will be applicable in a wide range of clinical scenarios as the indications for cochlear implantation continue to expand.


Assuntos
Implante Coclear/métodos , Terapia Combinada/métodos , Audição/fisiologia , Neuroma Acústico/cirurgia , Adolescente , Idoso , Austrália/epidemiologia , Terapia Combinada/estatística & dados numéricos , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Nervo Facial/cirurgia , Estudos de Viabilidade , Seguimentos , Testes Auditivos/métodos , Humanos , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/epidemiologia , Neuroma Acústico/diagnóstico por imagem , Neuroma Acústico/patologia , Neuroma Acústico/reabilitação , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Centros de Atenção Terciária , Resultado do Tratamento
6.
PLoS One ; 15(6): e0234623, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32555743

RESUMO

OBJECTIVES: Accumulating evidence points to a relationship between hearing function and cognitive ability in later life. However, the exact mechanisms of this relationship are still unclear. This study aimed to characterise latent cognitive trajectories in recall memory and identify their association with subsequent risk of hearing impairment. METHODS: We analysed data from the English Longitudinal Study of Ageing Wave 1 (2002/03) until Wave 7 (2014/15). The study population consisted of 3,615 adults aged 50+ who participated in the first wave of the English Longitudinal Study of Ageing, who had no self-reported hearing impairment in Wave 1, and who underwent a hearing test in Wave 7. Respondents were classified as having hearing impairment if they failed to hear tones quieter than 35 dB HL in the better ear. RESULTS: The trajectories of recall memory scores were grouped using latent class growth mixture modelling and were related to the presence of hearing impairment in Wave 7. Models estimating 1-class through 5-class recall memory trajectories were compared and the best-fitting models were 4-class trajectories. The different recall memory trajectories represent different starting points and mean of the memory scores. Compared to respondents with the highest recall memory trajectory, other trajectories were increasingly likely to develop later hearing impairment. CONCLUSIONS: Long-term changes in cognitive ability predict hearing impairment. Further research is required to identify the mechanisms explaining the association between cognitive trajectories and hearing impairment, as well as to determine whether intervention for maintenance of cognitive function also give benefit on hearing function among older adults.


Assuntos
Envelhecimento/psicologia , Disfunção Cognitiva/epidemiologia , Perda Auditiva/epidemiologia , Transtornos da Memória/epidemiologia , Rememoração Mental , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Inglaterra/epidemiologia , Feminino , Testes Auditivos/métodos , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade
7.
Pediatrics ; 146(1)2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32591436

RESUMO

Congenital cytomegalovirus (cCMV) is the most common congenital infection and is associated with sensorineural hearing loss, developmental delays, and visual impairment. The clinical presentation of cCMV is variable, and the majority (80%-90%) of newborns will never manifest any clinical symptoms. Given the clinical heterogeneity of cCMV infection, it is challenging to identify which newborns may benefit from testing. Recently, certain states have implemented a targeted screening program in which newborns who fail the newborn hearing screen are tested for cCMV. Clinicians and legislative bodies have been propelled into debates about the ethical and moral permissibility of a targeted cCMV screening approach. Those who oppose this screening approach describe undue burden on patients, families, and the health care system because the majority of newborns who fail the newborn hearing screen and have cCMV will not go on to have any sequelae related to cCMV, including hearing loss. However, those who support this screening approach cite the importance of early detection and ongoing surveillance for hearing loss and developmental delays in this high-risk group of newborns. This debate will be considered by experts in the field.


Assuntos
Infecções por Citomegalovirus/congênito , Diagnóstico Precoce , Perda Auditiva Neurossensorial/diagnóstico , Triagem Neonatal/métodos , Citomegalovirus , Infecções por Citomegalovirus/complicações , Infecções por Citomegalovirus/diagnóstico , Perda Auditiva Neurossensorial/etiologia , Testes Auditivos/métodos , Humanos , Recém-Nascido
8.
Codas ; 32(3): e20180179, 2020.
Artigo em Português, Inglês | MEDLINE | ID: mdl-32578835

RESUMO

PURPOSE: To analyze the quality indicators of the hearing screening program and to evaluate lingual frenulum in newborns, in terms of coverage rates, duration of hearing screening, referral indexes and prevalence of ankyloglossia in a university hospital specializing in mother and child care. METHOD: This is a cross-sectional study, in which we analyzed the database of the newborn hearing screening and lingual frenulum assessment program for the period between September 2015 and August 2016. RESULTS: During the study period, 2,345 babies were born at the institution, 1,380 (58.8%) underwent newborn hearing screening and 1,350 (57.6%) were diagnosed with a lingual frenulum. Mean gestational age was 39 weeks (± 1.6), birth weight 3478g (± 469.2) and 69% were boys. In newborn hearing screening, 95.7% of the 1,380 babies screened were discharged with guidance, 2.4% were referred for auditory monitoring and 1.9% of babies were referred for auditory diagnosis. In lingual frenulum assessment, 123 (9.1%) of the 1,350 evaluated, had ankyloglossia, 85 were boys and 47 girls. CONCLUSION: The indicators of the time of life in which the hearing screening is performed, the referral indices and ankyloglossia prevalence are in line with those reported in the literature; however, coverage rates were lower than recommended and do not comply with Brazilian law.


Assuntos
Freio Lingual , Triagem Neonatal , Indicadores de Qualidade em Assistência à Saúde , Anquiloglossia , Brasil , Criança , Estudos Transversais , Feminino , Testes Auditivos , Humanos , Lactente , Recém-Nascido , Masculino , Triagem Neonatal/normas
9.
Rev Saude Publica ; 54: 44, 2020.
Artigo em Inglês, Português | MEDLINE | ID: mdl-32374803

RESUMO

OBJECTIVE: To evaluate Newborn Hearing Screening Program of Hospital Regional de Sobradinho, from January 2016 to December 2017, according to Multiprofessional Committee on Auditory Health parameters and Joint Committee on Infant Hearing (JCIH) recommendations, as well as to describe the prevalence of risk factors for hearing loss within the study population and their impact on the respective program. METHOD: This is a quantitative, cross-sectional and retrospective study that carefully analyzed registration books of screened newborns. It was established the prevalence of "pass" and "fail" in test and retest, retest percentage of attendance and referral for audiological diagnosis. Risk factors for hearing loss were described, as well as their influence on "pass" and "fail" rates. Inferential statistical analysis was performed using chi-square test and Anderson-Darling test, with 5% reliability index. RESULTS: A total of 3,981 newborns were screened; 2,963 (74.4%) presented no risk factors whereas 1,018 (25.6%) did, prematurity being the most frequent (51.6%). In the test, 166 (4.2%) failed and 118 (71.1%) attended the retest. The referral rate for diagnosis was 0.3%. CONCLUSION: Regarding the percentage of referral for diagnosis, the program reached indexes recommended by the Joint Committee on Infant Hearing and Multiprofessional Committee on Auditory Health. The most prevalent risk factor within the population was prematurity.


Assuntos
Testes Auditivos/métodos , Triagem Neonatal/métodos , Avaliação de Programas e Projetos de Saúde , Brasil/epidemiologia , Estudos Transversais , Perda Auditiva/diagnóstico , Perda Auditiva/epidemiologia , Testes Auditivos/normas , Testes Auditivos/estatística & dados numéricos , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Registros Médicos , Triagem Neonatal/normas , Prevalência , Estudos Retrospectivos , Fatores de Risco
10.
PLoS One ; 15(5): e0232900, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32413090

RESUMO

Congenital deafness in the domestic dog is usually related to the presence of white pigmentation, which is controlled primarily by the piebald locus on chromosome 20 and also by merle on chromosome 10. Pigment-associated deafness is also seen in other species, including cats, mice, sheep, alpacas, horses, cows, pigs, and humans, but the genetic factors determining why some piebald or merle dogs develop deafness while others do not have yet to be determined. Here we perform a genome-wide association study (GWAS) to identify regions of the canine genome significantly associated with deafness in three dog breeds carrying piebald: Dalmatian, Australian cattle dog, and English setter. We include bilaterally deaf, unilaterally deaf, and matched control dogs from the same litter, phenotyped using the brainstem auditory evoked response (BAER) hearing test. Principal component analysis showed that we have different distributions of cases and controls in genetically distinct Dalmatian populations, therefore GWAS was performed separately for North American and UK samples. We identified one genome-wide significant association and 14 suggestive (chromosome-wide) associations using the GWAS design of bilaterally deaf vs. control Australian cattle dogs. However, these associations were not located on the same chromosome as the piebald locus, indicating the complexity of the genetics underlying this disease in the domestic dog. Because of this apparent complex genetic architecture, larger sample sizes may be needed to detect the genetic loci modulating risk in piebald dogs.


Assuntos
Surdez/veterinária , Doenças do Cão/genética , Animais , Estudos de Casos e Controles , Surdez/congênito , Surdez/genética , Cães , Potenciais Evocados Auditivos , Loci Gênicos , Predisposição Genética para Doença , Estudo de Associação Genômica Ampla , Testes Auditivos , Polimorfismo de Nucleotídeo Único , Seleção Artificial , Pigmentação da Pele/genética
11.
PLoS One ; 15(4): e0232024, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32324825

RESUMO

High-speed trains are operated in increasingly complex railway networks and continual improvement of driver assistance systems is necessary to maintain safety. Speech offers the opportunity to provide information to the driver without disrupting visual attention. However, it is not known whether the transient pressure changes inside trains passing through tunnels interfere with speech intelligibility. Our primary goal was to test whether the most severe pressure variations occurring in high-speed trains (25 hPa in 2 s) affect speech intelligibility in individuals with normal hearing ability and secondly whether a potential effect would depend on the direction of the pressure change. A cross-over design was used to compare speech intelligibility, measured with the monosyllable word test by Wallenberg and Kollmeier, in steady ambient pressure versus subsequent to pressure events, both realised in a pressure chamber. Since data for a power calculation did not exist, we conducted a pilot study with 20 participants to estimate variance of intra-individual differences. The upper 80% confidence limit guided sample size of the main campaign, which was performed with 72 participants to identify a 10% difference while limiting alpha (5%) and beta error (10%). On average, a participant understood 0.7 fewer words following a pressure change event compared to listening in steady ambient pressure. However, this intra-individual differences varied strongly between participants, standard deviation (SD) ± 4.5 words, resulting in a negligible effect size of 0.1 and the Wilcoxon signed rank test (Z = -1.26; p = 0.21) did not distinguish it from chance. When comparing decreasing and increasing pressure events an average of 0.2 fewer words were understood (± 3.9 SD). The most severe pressure changes expected to occur in high-speed trains passing through tunnels do not interfere with speech intelligibility and are in itself not a risk factor for loss of verbal information transmission.


Assuntos
Orelha Média/fisiologia , Inteligibilidade da Fala/fisiologia , Percepção da Fala/fisiologia , Adulto , Pressão Atmosférica , Estudos Cross-Over , Feminino , Testes Auditivos , Humanos , Masculino , Ruído , Projetos Piloto , Estudos Prospectivos , Ferrovias , Tamanho da Amostra , Adulto Jovem
12.
Otolaryngol Head Neck Surg ; 162(6): 826-838, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32228135

RESUMO

OBJECTIVE: School hearing screening is a public health intervention that can improve care for children who experience hearing loss that is not detected on or develops after newborn screening. However, implementation of school hearing screening is sporadic and supported by mixed evidence to its economic benefit. This scoping review provides a summary of all published cost-effectiveness studies regarding school hearing screening programs globally. At the time of this review, there were no previously published reviews of a similar nature. DATA SOURCES: A structured search was applied to 4 databases: PubMed (Medline), Embase, CINAHL, and Cochrane Library. REVIEW METHODS: The database search was carried out by 2 independent researchers, and results were reported in accordance with the PRISMA-ScR checklist and the JBI methodology for scoping reviews. Studies that included a cost analysis of screening programs for school-aged children in the school environment were eligible for inclusion. Studies that involved evaluations of only neonatal or preschool programs were excluded. RESULTS: Four of the 5 studies that conducted a cost-effectiveness analysis reported that school hearing screening was cost-effective through the calculation of incremental cost-effectiveness ratios (ICERs) via either quality- or disability-adjusted life years. One study reported that a new school hearing screening program dominated the existing program; 2 studies reported ICERs ranging from 1079 to 4304 international dollars; and 1 study reported an ICER of £2445. One study reported that school-entry hearing screening was not cost-effective versus no screening. CONCLUSION: The majority of studies concluded that school hearing screening was cost-effective. However, significant differences in methodology and region-specific estimates of model inputs limit the generalizability of these findings.


Assuntos
Perda Auditiva/diagnóstico , Testes Auditivos/economia , Audição/fisiologia , Programas de Rastreamento/métodos , Instituições Acadêmicas , Criança , Análise Custo-Benefício , Perda Auditiva/economia , Humanos , Qualidade de Vida
13.
Vestn Otorinolaringol ; 85(1): 25-29, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32241984

RESUMO

MATERIAL AND METHODS: The study included 125 patients with middle ear cholesteatoma, from 1 year to 17 years (131 cases - 6 patients had bilateral cholesteatoma). All patients were operated in the ENT department of St. Petersburg State Medical University from 2000 to 2017. A comparative analysis of the clinical course and results of surgical treatment of the middle ear cholesteatoma in two age groups was performed: 1 group (1-6 years) - 34 patients (37 cases); 2 group (7-17 years) - 91 patients (94 cases). RESULTS AND DISCUSSION: The average duration of the period from diagnosis to surgery was 7.1±6,4 months in the 1 group and 27.3±23.1 months in the 2 group. This is due to a brighter and more aggressive manifestation of cholesteatoma in children under 7 years old. Due to extensive bone destruction and cholesteatoma, 30% of children of the 1st group underwent radical surgery on the middle ear, in the 2nd group - only 15%. The postoperative period in children under 7 years was more unfavorably: large radical cavities, their late epithelization, growth of granulation tissue. The percentage of cholesteatoma recurrence after hearing-saving operations in the 1st group was 50%, in the 2nd group - 25%. CONCLUSION: The tendency to a more unfavorable course of the disease in young children has been identified. This must be taken into account in choosing the type of operation and predicting the course of the disease.


Assuntos
Colesteatoma da Orelha Média , Criança , Pré-Escolar , Orelha Média , Audição , Testes Auditivos , Humanos , Recidiva , Estudos Retrospectivos
14.
East Mediterr Health J ; 26(2): 176-181, 2020 Feb 24.
Artigo em Inglês | MEDLINE | ID: mdl-32141595

RESUMO

Background: In low and middle-income countries where the health care is in a weakened state, spending money on unaffordable and probably unnecessary investigations might be substituted by a reliable, simple and more informative tool that can deal with the problem. Aims: To examine current medical practice of measuring auditory brainstem response for all children with autistic spectrum disorder, and assess the value of this test in these children and its applicability in low and middle-income countries such as Libya. Methods: We reviewed the medical records of all children with autistic spectrum disorder who presented to neurodevelopment clinics of Al-Khadra Teaching Hospital, Tripoli, Libya between January 2010 and December 2014. Results: In 71 of 2368 children with autistic spectrum disorder, the family were concerned about their children's hearing and reaction to loud noises. Auditory brainstem response confirmed that 26 of these 71 children had sensorineural hearing loss. Conclusion: We consider auditory brainstem response measurement to be unnecessary in children with autistic spectrum disorder without clinical signs suggesting hearing impairment and without any parental concerns about hearing.


Assuntos
Transtorno Autístico , Perda Auditiva Neurossensorial/diagnóstico , Testes Auditivos , Criança , Pré-Escolar , Países em Desenvolvimento , Feminino , Humanos , Líbia , Masculino
15.
Ann Otol Rhinol Laryngol ; 129(8): 755-766, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32146824

RESUMO

OBJECTIVES: This study examined the association between pure tone hearing sensitivity and music listening behaviors among traditional college-aged students and sought to determine factors that mediate hearing sensitivity, including health and fitness levels, gender, and personal listening device (PLD) use. METHODS: A convenience sample of college students (N = 182; 133 females, 49 males, mean age = 19.8 ± 1.4 year, average PLD use = 1.52 ± 7.1 hours•day-1) completed hearing assessments, music listening behavior questionnaires, and health and fitness tests. RESULTS: Most students listened to music at safe intensity levels (<80 dBA), though 18% had higher hearing levels (≥25 dB HL at one of the measured frequencies). Longer listening duration behavior approached but did not reach a statistical association with compromised hearing sensitivity. Of all variables measured, including cardiovascular health, fitness, and music listening, two variables: total cholesterol: triglycerides (TC:TG) and total cholesterol: high-density lipoproteins (TC:HDL) significantly associated with hearing sensitivity at 2 kHz. The odds hearing loss occurring at 4 kHz was 59% lower in females compared with males. CONCLUSION: The majority of college students had healthy music listening behavior and fitness, contributing to normal hearing sensitivity in most. In cases where greater hearing threshold levels at one or more frequencies was detected, TC:HDL and TC:TG were statistically related and at 2 kHz, males were more likely to demonstrate higher listening levels compared with females of similar health and fitness level.


Assuntos
Percepção Auditiva/fisiologia , Limiar Auditivo/fisiologia , Doenças Cardiovasculares/fisiopatologia , Nível de Saúde , Perda Auditiva Provocada por Ruído/fisiopatologia , Estudantes/psicologia , Adolescente , Adulto , Doenças Cardiovasculares/etiologia , Feminino , Perda Auditiva Provocada por Ruído/complicações , Perda Auditiva Provocada por Ruído/psicologia , Testes Auditivos , Humanos , Masculino , Inquéritos e Questionários , Adulto Jovem
16.
Hum Genet ; 139(4): 521-530, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32002660

RESUMO

Newborn hearing screening is not designed to detect delayed-onset prelingual hearing loss or aminoglycoside-antibiotic-induced ototoxicity. Cases with severe to profound hearing loss have been reported to have been missed by newborn hearing screens. The aim of this study was to evaluate the efficacy of concurrent hearing and genetic screening in the general population and demonstrate its benefits in practice. Enrolled newborns received concurrent hearing and genetic screens between September 1, 2015 and January 31, 2018. Of the 239,636 eligible infants (median age, 19 months), 548 (0.23%) had prelingual hearing loss. Genetic screening identified 14 hearing loss patients with positive genotypes and 27 patients with inconclusive genotypes who had passed the hearing screens. In addition, the genetic screen identified 0.23% (570/239,636) of the newborns and their family members as at-risk for ototoxicity, which is undetectable by hearing screens. In conclusion, genetic screening complements newborn hearing screening by improving the detection of infants at risk of hereditary hearing loss and ototoxicity, and by informing genotype-based clinical management for affected infants and their family members. Our findings suggest that the practice should be further validated in other populations and rigorous cost-effectiveness analyses are warranted.


Assuntos
Testes Genéticos , Perda Auditiva , Triagem Neonatal , Feminino , Perda Auditiva/diagnóstico , Perda Auditiva/genética , Testes Auditivos , Humanos , Lactente , Recém-Nascido , Masculino , Estudos Retrospectivos
17.
Clin Interv Aging ; 15: 75-82, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32021135

RESUMO

Objective: The present study aimed to identify the reliability and validity of a screening tool for the elderly who wish to check their level of hearing loss by themselves. Design: A total of 170 older adults with different hearing levels participated. The Self-Assessment for Hearing Screening of the Elderly-Revised (SHSE-R) consisted of 20 questions measured on a 5-point scale and developed in terms of characteristics of age-related hearing loss. For reliability, the subjects responded to SHSE-R twice with a three-week interval. They also took various subjective and objective hearing tests and a working memory test and filled out two other questionnaires for validation. Results: SHSE-R showed a high internal consistency and a high reliability when comparing test-retest scores. Its content validity was as high as 0.88-1. Convergent validity supported SHSE-R and its subcategories while showing either a positive or negative correlation with pure-tone average, word recognition scores, and otoacoustic emission tests. Construct validity was proved by a moderate negative correlation with the tests of speech in noise, speech with fast speed, and working memory. In criterion validity, a strong positive correlation existed between SHSE-R and the other questionnaires, except for a group with severe hearing loss. The factor analysis showed similar results to the original version of SHSE having three factors, although some items were interchanged. Conclusion: We confirmed that SHSE-R was well developed with both excellent internal consistency and test-retest reliability and valuable convergent, construct, and criterion validities, consequently making SHSE-R useful for self-checking hearing loss in the elderly.


Assuntos
Autoavaliação Diagnóstica , Perda Auditiva , Testes Auditivos/métodos , Memória de Curto Prazo , Idoso , Feminino , Avaliação Geriátrica/métodos , Perda Auditiva/diagnóstico , Perda Auditiva/psicologia , Humanos , Masculino , Programas de Rastreamento/métodos , Qualidade de Vida , Reprodutibilidade dos Testes , Inquéritos e Questionários
18.
Codas ; 32(1): e20180139, 2020.
Artigo em Português, Inglês | MEDLINE | ID: mdl-32022219

RESUMO

PURPOSE: To establish the relationship between the performance on word recognition tasks, using words with and without sense and degree, and the configuration of hearing loss, by using Speech Inteligibility Index (SII) values as indicators, in children with hearing loss. METHODS: SII were established for 55 and 65 Decibel of Sound Pressure Level (dB SPL) input sounds of ten children presenting bilateral sensorineural hearing loss (SNHL), adapted with bilateral hearing aids, and who have oral language as the main mode of communication. The children were submitted to a word and nonsense-word repetition task of two or three intensity degrees. Their productions were analyzed according to the Word Association for Syllable Perception (WASP) Protocol. In the data analysis, the values of SII were compared with the results obtained in each analysis criterion. RESULTS: Pertaining to the words, there was statistically significant difference between the two types of stimuli in 55 dBSPL. As for the performance of consonants and point of articulation, there was a statistically significant difference between stimuli types in 65 and 55 dB SPL, and between intensities 65 and 55 dB SPL in nonsense words. CONCLUSION: Overall, there was no regularity in the relationship between hearing ability and performance in speech perception tasks. The results suggest that performance in the nonsense words recognition tasks was more related to intelligibility index than to words with meaning, possibly because it limits semantic closure strategies by the subject.


Assuntos
Auxiliares de Audição , Perda Auditiva Neurossensorial/diagnóstico , Inteligibilidade da Fala , Percepção da Fala , Estimulação Acústica/métodos , Estimulação Acústica/normas , Limiar Auditivo , Criança , Pré-Escolar , Protocolos Clínicos , Perda Auditiva Neurossensorial/reabilitação , Testes Auditivos , Humanos , Desenvolvimento da Linguagem
19.
Am J Otolaryngol ; 41(2): 102397, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32070666

RESUMO

PURPOSE: Although bilateral same-day tympanoplasty is a faster and more comfortable procedure for patients, it is rarely performed due to its theoretical risks. The present study aims to evaluate the results of patients who underwent bilateral same-day endoscopic tympanoplasty. MATERIALS AND METHODS: In this study, 26 patients and 52 ears were evaluated. Postoperative anatomic success rate, pre- and postoperative hearing test results, hearing gains and postoperative complications were recorded. RESULTS: Postoperative anatomic success rate was 92.3% (48/52). Audiological tests revealed the preoperative air-bone gap (ABG) as 19.1 ± 8.8 (7-35) dB and postoperative ABG as 9.8 ± 5.7 (5-25) dB. Postoperative ABG decreased significantly (p: <0.001) and 9.2 ± 4.6 (2-23) dB hearing gain was obtained. We did not observe any significant complications. CONCLUSION: Bilateral same-day endoscopic tympanoplasty is a feasible surgical procedure with good anatomic and functional outcomes, low complication rate and good postoperative patient comfort.


Assuntos
Procedimentos Cirúrgicos Ambulatórios/métodos , Endoscopia/métodos , Timpanoplastia/métodos , Audição , Testes Auditivos , Humanos , Complicações Pós-Operatórias , Resultado do Tratamento , Membrana Timpânica/anatomia & histologia , Membrana Timpânica/cirurgia
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