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1.
Biochemistry (Mosc) ; 86(6): 657-666, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34225589

RESUMO

Ischemic brain injuries are accompanied by the long-term changes in gene expression in the hippocampus, the limbic system structure, involved in the regulation of key aspects of the higher nervous activity, such as cognitive functions and emotions. The altered expression of genes and proteins encoded by them may be related to the development of post-ischemic psycho-emotional and cognitive disturbances. Activation of neuroinflammation following stroke in the hippocampus has been suggested to play an essential role in induction of long-lasting consequences. Identification of changes in the gene expression patterns after ischemia and investigation of the dynamics of these changes in the hippocampus are the necessary first steps toward understanding molecular pathways responsible for the development of post-stroke cognitive impairments and mental pathologies.


Assuntos
Isquemia Encefálica/genética , Transtornos Cognitivos/etiologia , Hipocampo/metabolismo , Transtornos Mentais/etiologia , Acidente Vascular Cerebral/genética , Animais , Lesões Encefálicas , Isquemia Encefálica/complicações , Isquemia Encefálica/metabolismo , Cognição , Depressão/etiologia , Regulação da Expressão Gênica , Humanos , Inflamação , Acidente Vascular Cerebral/complicações , Acidente Vascular Cerebral/metabolismo
3.
Artigo em Inglês | MEDLINE | ID: covidwho-1270632

RESUMO

INTRODUCTION: Healthcare workers are vulnerable to adverse mental health impacts of the COVID-19 pandemic. We assessed prevalence of mental disorders and associated factors during the first wave of the pandemic among healthcare professionals in Spain. METHODS: All workers in 18 healthcare institutions (6 AACC) in Spain were invited to web-based surveys assessing individual characteristics, COVID-19 infection status and exposure, and mental health status (May 5 - September 7, 2020). We report: probable current mental disorders (Major Depressive Disorder-MDD- [PHQ-8≥10], Generalized Anxiety Disorder-GAD- [GAD-7≥10], Panic attacks, Posttraumatic Stress Disorder -PTSD- [PCL-5≥7]; and Substance Use Disorder -SUD-[CAGE-AID≥2]. Severe disability assessed by the Sheehan Disability Scale was used to identify probable "disabling" current mental disorders. RESULTS: 9,138 healthcare workers participated. Prevalence of screen-positive disorder: 28.1% MDD; 22.5% GAD, 24.0% Panic; 22.2% PTSD; and 6.2% SUD. Overall 45.7% presented any current and 14.5% any disabling current mental disorder. Workers with pre-pandemic lifetime mental disorders had almost twice the prevalence than those without. Adjusting for all other variables, odds of any disabling mental disorder were: prior lifetime disorders (TUS: OR=5.74; 95%CI 2.53-13.03; Mood: OR=3.23; 95%CI:2.27-4.60; Anxiety: OR=3.03; 95%CI:2.53-3.62); age category 18-29 years (OR=1.36; 95%CI:1.02-1.82), caring "all of the time" for COVID-19 patients (OR=5.19; 95%CI: 3.61-7.46), female gender (OR=1.58; 95%CI: 1.27-1.96) and having being in quarantine or isolated (OR= 1.60; 95CI:1.31-1.95). CONCLUSIONS: One in seven Spanish healthcare workers screened positive for a disabling mental disorder during the first wave of the COVID-19 pandemic. Workers reporting pre-pandemic lifetime mental disorders, those frequently exposed to COVID-19 patients, infected or quarantined/isolated, female workers, and auxiliary nurses should be considered groups in need of mental health monitoring and support.


Assuntos
COVID-19 , Pessoal de Saúde , Transtornos Mentais/epidemiologia , Saúde Mental , Doenças Profissionais/epidemiologia , Adolescente , Adulto , COVID-19/epidemiologia , Estudos Transversais , Feminino , Pessoal de Saúde/psicologia , Humanos , Masculino , Transtornos Mentais/etiologia , Pessoa de Meia-Idade , Doenças Profissionais/etiologia , Prevalência , Espanha/epidemiologia , Adulto Jovem
4.
Aust J Gen Pract ; 50(7): 472-477, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-34189550

RESUMO

BACKGROUND: Psychological issues are common presentations in general practice. The COVID-19 pandemic has created a 'perfect storm' for the deterioration of mental health. General practitioners (GPs) are ideally placed to provide supports for people with mental health issues. OBJECTIVE: The objective of this article is to provide an overview of management approaches for mental health issues, paying attention to fostering resilience and lifestyle factors, particularly during the COVID-19 pandemic period. DISCUSSION: While feelings of fear and anxiety are expected in these uncertain times, some people may experience an exacerbation of a mental illness or develop a mental health issue for the first time during the COVID-19 pandemic. A list of resources available to GPs is provided, and case studies are used to demonstrate how these resources can be used to support assessment and management during the COVID-19 pandemic.


Assuntos
Ansiedade/terapia , COVID-19/complicações , COVID-19/psicologia , Depressão/terapia , Medicina Geral , Transtornos Mentais/terapia , Adaptação Psicológica , Ansiedade/diagnóstico , Ansiedade/etiologia , COVID-19/terapia , Depressão/diagnóstico , Depressão/etiologia , Feminino , Humanos , Masculino , Transtornos Mentais/diagnóstico , Transtornos Mentais/etiologia , Pessoa de Meia-Idade , Adulto Jovem
7.
Artigo em Inglês | MEDLINE | ID: mdl-34127211

RESUMO

INTRODUCTION: Healthcare workers are vulnerable to adverse mental health impacts of the COVID-19 pandemic. We assessed prevalence of mental disorders and associated factors during the first wave of the pandemic among healthcare professionals in Spain. METHODS: All workers in 18 healthcare institutions (6 AACC) in Spain were invited to web-based surveys assessing individual characteristics, COVID-19 infection status and exposure, and mental health status (May 5 - September 7, 2020). We report: probable current mental disorders (Major Depressive Disorder-MDD- [PHQ-8≥10], Generalized Anxiety Disorder-GAD- [GAD-7≥10], Panic attacks, Posttraumatic Stress Disorder -PTSD- [PCL-5≥7]; and Substance Use Disorder -SUD-[CAGE-AID≥2]. Severe disability assessed by the Sheehan Disability Scale was used to identify probable "disabling" current mental disorders. RESULTS: 9,138 healthcare workers participated. Prevalence of screen-positive disorder: 28.1% MDD; 22.5% GAD, 24.0% Panic; 22.2% PTSD; and 6.2% SUD. Overall 45.7% presented any current and 14.5% any disabling current mental disorder. Workers with pre-pandemic lifetime mental disorders had almost twice the prevalence than those without. Adjusting for all other variables, odds of any disabling mental disorder were: prior lifetime disorders (TUS: OR=5.74; 95%CI 2.53-13.03; Mood: OR=3.23; 95%CI:2.27-4.60; Anxiety: OR=3.03; 95%CI:2.53-3.62); age category 18-29 years (OR=1.36; 95%CI:1.02-1.82), caring "all of the time" for COVID-19 patients (OR=5.19; 95%CI: 3.61-7.46), female gender (OR=1.58; 95%CI: 1.27-1.96) and having being in quarantine or isolated (OR= 1.60; 95CI:1.31-1.95). CONCLUSIONS: One in seven Spanish healthcare workers screened positive for a disabling mental disorder during the first wave of the COVID-19 pandemic. Workers reporting pre-pandemic lifetime mental disorders, those frequently exposed to COVID-19 patients, infected or quarantined/isolated, female workers, and auxiliary nurses should be considered groups in need of mental health monitoring and support.


Assuntos
COVID-19 , Pessoal de Saúde , Transtornos Mentais/epidemiologia , Saúde Mental , Doenças Profissionais/epidemiologia , Adolescente , Adulto , COVID-19/epidemiologia , Estudos Transversais , Feminino , Pessoal de Saúde/psicologia , Humanos , Masculino , Transtornos Mentais/etiologia , Pessoa de Meia-Idade , Doenças Profissionais/etiologia , Prevalência , Espanha/epidemiologia , Adulto Jovem
8.
Neuropsychology ; 35(4): 366-373, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-34043387

RESUMO

OBJECTIVE: This cross-sectional study examined the influence of education on executive functions, behavioral problems and functional performance in people with chronic schizophrenia. METHOD: Our sample was composed of 116 subjects with a schizophrenia diagnosis (evolution time = 17.5 ± 9.5 years) from consecutive referrals to the Rehabilitation Unit of Benito Menni Hospital (Valladolid, Spain). All participants completed an extensive standardized protocol including a neuropsychological testing of executive functions (processing speed, working memory, inhibition, interference control, mental flexibility), the assessment of behavioral symptoms, and functional performance. Hierarchical regression models (HRMs) were carried out to determine whether education (in years) relates to executive functions after controlling for the effect of demographics, IQ, and clinical factors. RESULTS: Both IQ and years of education were associated with a later onset of the illness. Specifically, high education (in years) significantly correlated with fewer behavioral problems and better functional performance in daily life. Further, HRMs showed that education was associated with digit span and sematic verbal fluency tasks after controlling for the effect of age, sex, and IQ as covariates. CONCLUSIONS: Higher education may ameliorate executive deficits in patients with chronic schizophrenia and, in turn, diminish the behavioral and functional problems of the illness. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Assuntos
Escolaridade , Função Executiva , Transtornos Mentais/etiologia , Transtornos Mentais/psicologia , Desempenho Físico Funcional , Psicologia do Esquizofrênico , Adulto , Idade de Início , Doença Crônica , Estudos Transversais , Feminino , Humanos , Testes de Inteligência , Masculino , Memória de Curto Prazo , Pessoa de Meia-Idade , Testes Neuropsicológicos , Comportamento Problema , Análise de Regressão , Esquizofrenia/complicações , Esquizofrenia/reabilitação
9.
Curr Opin Psychiatry ; 34(4): 420-433, 2021 07 01.
Artigo em Inglês | MEDLINE | ID: covidwho-1238299

RESUMO

PURPOSE OF REVIEW: COVID-19 impacts multiple organ systems and is associated with high rates of morbidity and mortality. Pathogenesis of viral infection, co-morbidities, medical treatments, and psychosocial factors may contribute to COVID-19 related neuropsychological and psychiatric sequelae. This systematic review aims to synthesize available literature on psychiatric and cognitive characteristics of community-dwelling survivors of COVID-19 infection. RECENT FINDINGS: Thirty-three studies met inclusion/exclusion criteria for review. Emerging findings link COVID-19 to cognitive deficits, particularly attention, executive function, and memory. Psychiatric symptoms occur at high rates in COVID-19 survivors, including anxiety, depression, fatigue, sleep disruption, and to a lesser extent posttraumatic stress. Symptoms appear to endure, and severity of acute illness is not directly predictive of severity of cognitive or mental health issues. The course of cognitive and psychiatric sequelae is limited by lack of longitudinal data at this time. Although heterogeneity of study design and sociocultural differences limit definitive conclusions, emerging risk factors for psychiatric symptoms include female sex, perceived stigma related to COVID-19, infection of a family member, social isolation, and prior psychiatry history. SUMMARY: The extant literature elucidates treatment targets for cognitive and psychosocial interventions. Research using longitudinal, prospective study designs is needed to characterize cognitive and psychiatric functioning of COVID-19 survivors over the course of illness and across illness severity. Emphasis on delineating the unique contributions of premorbid functioning, viral infection, co-morbidities, treatments, and psychosocial factors to cognitive and psychiatric sequelae of COVID-19 is warranted.


Assuntos
COVID-19/complicações , COVID-19/psicologia , Transtornos Mentais/etiologia , Transtornos Mentais/psicologia , Feminino , Humanos , Estudos Prospectivos , SARS-CoV-2 , Índice de Gravidade de Doença
10.
PLoS One ; 16(5): e0251984, 2021.
Artigo em Inglês | MEDLINE | ID: covidwho-1234594

RESUMO

The COVID-19 pandemic has had a significant influence on the lives of people around the world and could be a risk factor for mental health diseases. This study aimed to explore the psychological impact of the COVID-19 pandemic by identifying patterns related to post-traumatic symptoms by considering personality and defensive styles. Specifically, it was hypothesized that neuroticism was negatively associated with impact of event, as opposed to extraversion, agreeableness, conscientiousness, and openness traits. The mediation role of mature, neurotic, and immature defenses in these relationships was also investigated. This study involved 557 Italian individuals (71.3% women, 28.7% men; Mage = 34.65, SD = 12.05), who completed an online survey including the Impact of Event Scale-Revised, Forty Item Defense Style Questionnaire (DSQ-40) and Ten Item Personality Inventory. Results showed a nonsignificant effect for extraversion and openness on impact of event. The negative influence of neuroticism was instead confirmed in a partial parallel mediation involving significant effects from immature and neurotic defenses in the indirect path. Finally, agreeableness and conscientiousness delineated two protective pathways regarding impact of event, determining two total parallel mediation models in which both these personality traits were negatively associated with immature defensive styles, and conscientiousness was also positively related to mature defenses. These findings provide an exploration post-traumatic symptom patterns during the COVID-19 pandemic, involving the big five personality traits and defense mechanisms. These results may be useful for developing interventions, treatments, and prevention activities.


Assuntos
COVID-19/psicologia , Transtornos Mentais/etiologia , Personalidade/fisiologia , Adulto , COVID-19/epidemiologia , Mecanismos de Defesa , Extroversão Psicológica , Feminino , Humanos , Itália/epidemiologia , Masculino , Pessoa de Meia-Idade , Neuroticismo , Pandemias , Inventário de Personalidade , SARS-CoV-2/isolamento & purificação , Inquéritos e Questionários , Transtornos Relacionados a Trauma e Fatores de Estresse/etiologia
12.
Rev Neurol ; 72(11): 384-396, 2021 06 01.
Artigo em Espanhol | MEDLINE | ID: covidwho-1248581

RESUMO

INTRODUCTION: Many patients with mild or severe COVID-19 do not make a full recovery and have a wide range of chronic symptoms for weeks or months after infection, often of a neurological, cognitive or psychiatric nature. The epidemiological evidence, diagnostic criteria and pathogenesis of post-COVID-19 syndrome are reviewed. DEVELOPMENT: Post-COVID-19 syndrome is defined by persistent clinical signs and symptoms that appear while or after suffering COVID-19, persist for more than 12 weeks and cannot be explained by an alternative diagnosis. The symptoms can fluctuate or cause relapses. It is a heterogeneous condition that includes post-viral chronic fatigue syndrome, sequelae in multiple organs and the effects of severe hospitalisation/post-intensive care syndrome. It has been reported in patients with mild or severe COVID-19 and irrespective of the severity of the symptoms in the acute phase. Between 10% and 65% of survivors who had mild/moderate COVID-19 present symptoms of post-COVID-19 syndrome for 12 weeks or more. At six months, subjects report an average of 14 persistent symptoms. The most common symptoms are fatigue, dyspnoea, anxiety, depression, and impaired attention, concentration, memory and sleep. The underlying biological mechanisms are unknown, although an abnormal or excessive autoimmune and inflammatory response may play an important role. CONCLUSIONS: Clinical manifestations are diverse, fluctuating and variable, although fatigue and neurocognitive complaints predominate. There is no defined consensus on post-COVID-19 syndrome and its diagnostic criteria have not been subjected to adequate psychometric evaluation.


Assuntos
COVID-19/complicações , SARS-CoV-2 , Autoimunidade , Encéfalo/metabolismo , COVID-19/diagnóstico , COVID-19/epidemiologia , COVID-19/fisiopatologia , Doenças Cardiovasculares/etiologia , Transtornos Cognitivos/etiologia , Transtornos Cognitivos/fisiopatologia , Infecções por Coronavirus/complicações , Dispneia/etiologia , Síndrome de Fadiga Crônica/etiologia , Gastroenteropatias/etiologia , Hospitalização , Interações Hospedeiro-Patógeno , Humanos , Inflamação , Transtornos Mentais/etiologia , Doenças do Sistema Nervoso/etiologia , Especificidade de Órgãos , Pandemias , Disautonomias Primárias/etiologia , Fatores de Risco , Síndrome Respiratória Aguda Grave/complicações
14.
Med J Malaysia ; 76(3): 284-290, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-34031324

RESUMO

INTRODUCTION: The Coronavirus Disease 2019 (COVID-19) has dramatically affected global healthcare systems. We aimed to determine the response of our paediatric surgical fraternity to a disease that overwhelmingly affects adults. MATERIALS AND METHODS: We conducted a cross-sectional questionnaire-based study over 6 weeks during a federally mandated lockdown. Using snowball sampling, we recruited paediatric surgeons, trainees and medical officers from paediatric surgical units in Malaysia. The anonymous online questionnaire covered sociodemographic information, changes in patient care, redeployment, concerns regarding family members, and impact on training. Mental well-being was assessed using the Depression, Anxiety and Stress Scale (DASS-21). Kruskal-Wallis, ANOVA and multiple regression analysis was used, with significance level 0.05. RESULTS: Of the 129 eligible participants, 100(77%) responded. Junior doctors had clinically higher levels of depression, anxiety, and stress. Age <30 years was significantly associated with anxiety. Junior doctors believed that redeployment led to loss of surgical skills (p<0.001) and trainees felt that clinical application of knowledge had reduced (p<0.020). CONCLUSION: Specific to our paediatric surgical community, this study highlights areas of concern, particularly among junior doctors. It is likely that recurrent cycles of the pandemic will occur soon. These issues must be addressed to preserve the mental and emotional well-being of all health care workers.


Assuntos
COVID-19 , Transtornos Mentais/etiologia , Doenças Profissionais/etiologia , Pediatras/psicologia , Pediatria/tendências , Especialidades Cirúrgicas/tendências , Cirurgiões/psicologia , Adulto , Ansiedade/diagnóstico , Ansiedade/epidemiologia , Ansiedade/etiologia , Atitude do Pessoal de Saúde , COVID-19/epidemiologia , COVID-19/prevenção & controle , COVID-19/psicologia , Criança , Estudos Transversais , Depressão/diagnóstico , Depressão/epidemiologia , Depressão/etiologia , Feminino , Humanos , Malásia/epidemiologia , Masculino , Transtornos Mentais/diagnóstico , Transtornos Mentais/epidemiologia , Saúde Mental , Doenças Profissionais/diagnóstico , Doenças Profissionais/epidemiologia , Saúde do Trabalhador , Estresse Ocupacional/diagnóstico , Estresse Ocupacional/epidemiologia , Estresse Ocupacional/etiologia , Pandemias , Pediatras/educação , Pediatras/tendências , Pediatria/educação , Padrões de Prática Médica , Escalas de Graduação Psiquiátrica , Especialidades Cirúrgicas/educação , Cirurgiões/educação , Cirurgiões/tendências , Inquéritos e Questionários
15.
Rev Neurol ; 72(11): 384-396, 2021 06 01.
Artigo em Espanhol | MEDLINE | ID: mdl-34042167

RESUMO

INTRODUCTION: Many patients with mild or severe COVID-19 do not make a full recovery and have a wide range of chronic symptoms for weeks or months after infection, often of a neurological, cognitive or psychiatric nature. The epidemiological evidence, diagnostic criteria and pathogenesis of post-COVID-19 syndrome are reviewed. DEVELOPMENT: Post-COVID-19 syndrome is defined by persistent clinical signs and symptoms that appear while or after suffering COVID-19, persist for more than 12 weeks and cannot be explained by an alternative diagnosis. The symptoms can fluctuate or cause relapses. It is a heterogeneous condition that includes post-viral chronic fatigue syndrome, sequelae in multiple organs and the effects of severe hospitalisation/post-intensive care syndrome. It has been reported in patients with mild or severe COVID-19 and irrespective of the severity of the symptoms in the acute phase. Between 10% and 65% of survivors who had mild/moderate COVID-19 present symptoms of post-COVID-19 syndrome for 12 weeks or more. At six months, subjects report an average of 14 persistent symptoms. The most common symptoms are fatigue, dyspnoea, anxiety, depression, and impaired attention, concentration, memory and sleep. The underlying biological mechanisms are unknown, although an abnormal or excessive autoimmune and inflammatory response may play an important role. CONCLUSIONS: Clinical manifestations are diverse, fluctuating and variable, although fatigue and neurocognitive complaints predominate. There is no defined consensus on post-COVID-19 syndrome and its diagnostic criteria have not been subjected to adequate psychometric evaluation.


Assuntos
COVID-19/complicações , SARS-CoV-2 , Autoimunidade , Encéfalo/metabolismo , COVID-19/diagnóstico , COVID-19/epidemiologia , COVID-19/fisiopatologia , Doenças Cardiovasculares/etiologia , Transtornos Cognitivos/etiologia , Transtornos Cognitivos/fisiopatologia , Infecções por Coronavirus/complicações , Dispneia/etiologia , Síndrome de Fadiga Crônica/etiologia , Gastroenteropatias/etiologia , Hospitalização , Interações Hospedeiro-Patógeno , Humanos , Inflamação , Transtornos Mentais/etiologia , Doenças do Sistema Nervoso/etiologia , Especificidade de Órgãos , Pandemias , Disautonomias Primárias/etiologia , Fatores de Risco , Síndrome Respiratória Aguda Grave/complicações
17.
Curr Opin Psychiatry ; 34(4): 420-433, 2021 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-34016818

RESUMO

PURPOSE OF REVIEW: COVID-19 impacts multiple organ systems and is associated with high rates of morbidity and mortality. Pathogenesis of viral infection, co-morbidities, medical treatments, and psychosocial factors may contribute to COVID-19 related neuropsychological and psychiatric sequelae. This systematic review aims to synthesize available literature on psychiatric and cognitive characteristics of community-dwelling survivors of COVID-19 infection. RECENT FINDINGS: Thirty-three studies met inclusion/exclusion criteria for review. Emerging findings link COVID-19 to cognitive deficits, particularly attention, executive function, and memory. Psychiatric symptoms occur at high rates in COVID-19 survivors, including anxiety, depression, fatigue, sleep disruption, and to a lesser extent posttraumatic stress. Symptoms appear to endure, and severity of acute illness is not directly predictive of severity of cognitive or mental health issues. The course of cognitive and psychiatric sequelae is limited by lack of longitudinal data at this time. Although heterogeneity of study design and sociocultural differences limit definitive conclusions, emerging risk factors for psychiatric symptoms include female sex, perceived stigma related to COVID-19, infection of a family member, social isolation, and prior psychiatry history. SUMMARY: The extant literature elucidates treatment targets for cognitive and psychosocial interventions. Research using longitudinal, prospective study designs is needed to characterize cognitive and psychiatric functioning of COVID-19 survivors over the course of illness and across illness severity. Emphasis on delineating the unique contributions of premorbid functioning, viral infection, co-morbidities, treatments, and psychosocial factors to cognitive and psychiatric sequelae of COVID-19 is warranted.


Assuntos
COVID-19/complicações , COVID-19/psicologia , Transtornos Mentais/etiologia , Transtornos Mentais/psicologia , Feminino , Humanos , Estudos Prospectivos , SARS-CoV-2 , Índice de Gravidade de Doença
19.
PLoS One ; 16(5): e0251984, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34010358

RESUMO

The COVID-19 pandemic has had a significant influence on the lives of people around the world and could be a risk factor for mental health diseases. This study aimed to explore the psychological impact of the COVID-19 pandemic by identifying patterns related to post-traumatic symptoms by considering personality and defensive styles. Specifically, it was hypothesized that neuroticism was negatively associated with impact of event, as opposed to extraversion, agreeableness, conscientiousness, and openness traits. The mediation role of mature, neurotic, and immature defenses in these relationships was also investigated. This study involved 557 Italian individuals (71.3% women, 28.7% men; Mage = 34.65, SD = 12.05), who completed an online survey including the Impact of Event Scale-Revised, Forty Item Defense Style Questionnaire (DSQ-40) and Ten Item Personality Inventory. Results showed a nonsignificant effect for extraversion and openness on impact of event. The negative influence of neuroticism was instead confirmed in a partial parallel mediation involving significant effects from immature and neurotic defenses in the indirect path. Finally, agreeableness and conscientiousness delineated two protective pathways regarding impact of event, determining two total parallel mediation models in which both these personality traits were negatively associated with immature defensive styles, and conscientiousness was also positively related to mature defenses. These findings provide an exploration post-traumatic symptom patterns during the COVID-19 pandemic, involving the big five personality traits and defense mechanisms. These results may be useful for developing interventions, treatments, and prevention activities.


Assuntos
COVID-19/psicologia , Transtornos Mentais/etiologia , Personalidade/fisiologia , Adulto , COVID-19/epidemiologia , Mecanismos de Defesa , Extroversão Psicológica , Feminino , Humanos , Itália/epidemiologia , Masculino , Pessoa de Meia-Idade , Neuroticismo , Pandemias , Inventário de Personalidade , SARS-CoV-2/isolamento & purificação , Inquéritos e Questionários , Transtornos Relacionados a Trauma e Fatores de Estresse/etiologia
20.
BMC Pediatr ; 21(1): 197, 2021 04 23.
Artigo em Inglês | MEDLINE | ID: mdl-33892662

RESUMO

BACKGROUND: Atopic diseases and behavioural difficulties in children have both been on the rise in recent decades. This study seeks to assess associations between atopic diseases and behavioural difficulties, examining the differences considering child age and how behavioural difficulties were reported (via self-report or parent-report). METHODS: Data on behavioural difficulties, assessed through the Strengths and Difficulties Questionnaire (SDQ), and on atopic diseases, assessed through the participant's medical history, were available for 2701 study participants aged 3 to 18 years. Associations between atopic diseases and behavioural difficulties were evaluated using linear regression analyses. We split the study sample into two groups. I: 3-to 10-year-olds/parent-reported SDQ (n = 1764), II: 11- to 18-year-olds/parent-reported SDQ (n = 937) and self-reported SDQ (n = 915). All analyses were adjusted for age, gender, and socioeconomic status. RESULTS: In younger children, atopic dermatitis was strongly associated with higher total difficulties scores, more emotional problems and conduct problems, and more symptoms of hyperactivity/inattention. Parents reported higher total difficulties scores, more emotional problems, and more peer-relationship problems for adolescents with bronchial asthma and other allergies, whereas the adolescents themselves reported more peer relationship problems. CONCLUSION: In younger children, atopic dermatitis is associated with internalizing and externalizing problems. In adolescents, bronchial asthma and other allergies are associated with a greater level of internalizing problems only. The findings further suggest that parents of adolescents are more likely to perceive associations between atopic diseases and behavioural difficulties than the adolescents themselves.


Assuntos
Transtornos Mentais , Comportamento Problema , Adolescente , Criança , Pré-Escolar , Humanos , Transtornos Mentais/epidemiologia , Transtornos Mentais/etiologia , Pais , Autorrelato , Inquéritos e Questionários
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