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1.
Rev. enferm. UERJ ; 28: e46505, jan.-dez. 2020.
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1120172

RESUMO

Objetivo: analisar a associação entre danos à saúde e qualidade de vida no trabalho de enfermeiros hospitalares. Método: estudo quantitativo, descritivo, transversal, com 145 enfermeiros, aprovado pela comissão de ética sob protocolos 1.634.051 e 1.643.912. Utilizaram-se estatísticas descritivas, análises bivariadas, teste qui-quadrado, cálculo da razão de chance e intervalos de confiança. Resultados: observou-se que o consumo de medicamentos provocado/agravado pelo trabalho aumentou em 2,31 vezes a chance de o enfermeiro ter baixa qualidade de vida no trabalho; transtornos do sono provocados/agravados pelo trabalho aumentou em 3,15 vezes a chance de ter baixa qualidade de vida no trabalho; cefaleia frequente provocada/agravada pelo trabalho aumentou a chance em 1,98 vezes de ter baixa qualidade de vida no trabalho. Conclusão: condições de trabalho impactam na saúde e qualidade de vida do trabalho do enfermeiro. Ambientes de trabalho adequados proporcionam satisfação pessoal e profissional, além de manterem a qualidade da força de trabalho do enfermeiro.


Objective: to examine the association between health harm and quality of life in the work of hospital nurses. Method: this quantitative, descriptive, cross-sectional study, with 145 nurses, after approval by research ethics committee ­ protolcols 1.634.051 and 1.643.912. Descriptive statistics, bivariate analyses, chi-square test, odds ratio and confidence intervals were used. Results: the odds of nurses' quality of life at work being poor were found to be increased 2.31 times by work-related or - aggravated medicine consumption; 3.15 times by work-related or -aggravated sleep disorders; and 1.98 times by frequent workrelated or -aggravated headache. Conclusion: working conditions impact on nurses' health and quality of life at work. Appropriate work environments favor personal and professional satisfaction and maintain the quality of the nurse's workforce.


Objetivo: examinar la asociación entre daños a la salud y calidad de vida en el trabajo de enfermeras hospitalarias. Método: estudio cuantitativo, descriptivo, transversal, con 145 enfermeros, previa aprobación del comité de ética en investigación - protolcols 1.634.051 y 1.643.912. Se utilizó estadística descriptiva, análisis bivariados, prueba de chi-cuadrado, razón de probabilidades e intervalos de confianza. Resultados: se encontró que las probabilidades de que la calidad de vida de las enfermeras en el trabajo sea deficiente aumentaban 2,31 veces por el consumo de medicamentos relacionados con el trabajo o agravados; 3,15 veces por trastornos del sueño relacionados con el trabajo o agravados; y 1,98 veces por dolor de cabeza frecuente relacionado con el trabajo o agravado. Conclusión: las condiciones laborales repercuten en la salud y la calidad de vida de las enfermeras en el trabajo. Los entornos laborales adecuados favorecen la satisfacción personal y profesional y mantienen la calidad de la fuerza laboral de la enfermería.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Qualidade de Vida , Condições de Trabalho , Saúde do Trabalhador , Hospitais Universitários , Enfermeiras e Enfermeiros , Automedicação , Transtornos do Sono-Vigília , Brasil , Distribuição de Qui-Quadrado , Intervalos de Confiança , Razão de Chances , Epidemiologia Descritiva , Estudos Transversais , Local de Trabalho , Cefaleia , Satisfação no Emprego
2.
BMC Res Notes ; 13(1): 493, 2020 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-33087166

RESUMO

OBJECTIVES: To assess prevalence and related factors of sleep disturbances among Saudi physicians during COVID-19 pandemic. Data were collected through a questionnaire including items about demographic characters, knowledge about covid-19 and items to assess sleep quality that were extracted from Pittsburgh Sleep Quality Index (PSQI) scale. RESULTS: Prevalence of sleep disorders was 43.9%, doctors in the age group of 31-40 years, associate consultants had a significant higher prevalence of sleep disorders. Medical interns and laboratory/pathology/microbiology doctors had a significant more difficulty in fall asleep during COVID-19, and internists and surgeons had a significant higher percent of those who used sleeping pills. Resident doctors had a significant higher percent of having trouble in staying awake, and residents and consultants had a significant higher percent of those who suffered decreased sleep duration. Sleep quality during COVID-19 was very good, fair good and very bad in 23.4%, 60% and 3.5% of HCW respectively. The study observed a negative impact of COVID-19 pandemic on HCW sleep quality. Hospitals administrations should provide optimal working hours with enough break and employ more doctors during the pandemic. Doctors experiencing sleep problems should have mandatory leaves.


Assuntos
Infecções por Coronavirus/psicologia , Estresse Ocupacional/etiologia , Pandemias , Médicos/psicologia , Pneumonia Viral/psicologia , Transtornos do Sono-Vigília/etiologia , Adulto , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Estresse Ocupacional/epidemiologia , Estresse Ocupacional/psicologia , Prevalência , Arábia Saudita/epidemiologia , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/psicologia , Inquéritos e Questionários
3.
Trials ; 21(1): 870, 2020 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-33087178

RESUMO

BACKGROUND: The acknowledgment of the mental health toll of the COVID-19 epidemic in healthcare workers has increased considerably as the disease evolved into a pandemic status. Indeed, high prevalence rates of depression, sleep disorders, and post-traumatic stress disorder (PTSD) have been reported in Chinese healthcare workers during the epidemic peak. Symptoms of psychological distress are expected to be long-lasting and have a systemic impact on healthcare systems, warranting the need for evidence-based psychological treatments aiming at relieving immediate stress and preventing the onset of psychological disorders in this population. In the current COVID-19 context, internet-based interventions have the potential to circumvent the pitfalls of face-to-face formats and provide the flexibility required to facilitate accessibility to healthcare workers. Online cognitive behavioral therapy (CBT) in particular has proved to be effective in treating and preventing a number of stress-related disorders in populations other than healthcare workers. The aim of our randomized controlled trial study protocol is to evaluate the efficacy of the 'My Health too' CBT program-a program we have developed for healthcare workers facing the pandemic-on immediate perceived stress and on the emergence of psychiatric disorders at 3- and 6-month follow-up compared to an active control group (i.e., bibliotherapy). METHODS: Powered for superiority testing, this six-site open trial involves the random assignment of 120 healthcare workers with stress levels > 16 on the Perceived Stress Scale (PSS-10) to either the 7-session online CBT program or bibliotherapy. The primary outcome is the decrease of PSS-10 scores at 8 weeks. Secondary outcomes include depression, insomnia, and PTSD symptoms; self-reported resilience and rumination; and credibility and satisfaction. Assessments are scheduled at pretreatment, mid-treatment (at 4 weeks), end of active treatment (at 8 weeks), and at 3-month and 6-month follow-up. DISCUSSION: This is the first study assessing the efficacy and the acceptability of a brief online CBT program specifically developed for healthcare workers. Given the potential short- and long-term consequences of the COVID-19 pandemic on healthcare workers' mental health, but also on healthcare systems, our findings can significantly impact clinical practice and management of the ongoing, and probably long-lasting, health crisis. TRIAL REGISTRATION: ClinicalTrials.gov NCT04362358 , registered on April 24, 2020.


Assuntos
Betacoronavirus/genética , Terapia Cognitivo-Comportamental/métodos , Infecções por Coronavirus/terapia , Pessoal de Saúde/psicologia , Intervenção Baseada em Internet/estatística & dados numéricos , Pneumonia Viral/terapia , Adulto , Idoso , Biblioterapia/métodos , Estudos de Casos e Controles , Terapia Cognitivo-Comportamental/estatística & dados numéricos , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/psicologia , Infecções por Coronavirus/virologia , Assistência à Saúde/estatística & dados numéricos , Depressão/epidemiologia , Depressão/prevenção & controle , Feminino , França/epidemiologia , Humanos , Masculino , Saúde Mental/normas , Pessoa de Meia-Idade , Pandemias , Pneumonia Viral/epidemiologia , Pneumonia Viral/psicologia , Pneumonia Viral/virologia , Prevalência , Estudos Prospectivos , Resiliência Psicológica , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/prevenção & controle , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Transtornos de Estresse Pós-Traumáticos/prevenção & controle , Resultado do Tratamento
4.
Sarcoidosis Vasc Diffuse Lung Dis ; 37(2): 169-178, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33093780

RESUMO

Rationale: An increased incidence of Obstructive Sleep Apnea (OSA) in sarcoidosis has been described in small sample size studies. Fatigue is common in sarcoidosis and OSA could be a relevant, treatable comorbidity. To date, the effect of Continuous Positive Airway Pressure (CPAP) on fatigue has never been assessed. Objectives: To investigate the prevalence of OSA in sarcoidosis, fatigue status and daytime sleepiness in patients of our center. To explore the effect of CPAP in fatigue and daytime sleepiness after 3 months using validated questionnaires. Method: Single group, one center, open-label prospective cohort study. Measurements and main result: We enrolled 68 patients and OSA was diagnosed in 60 (88.2%): 25 (36.8%) were mild while 35 (51.5%) were moderate-to-severe. 38 (55.9%) patients received CPAP but only 20 (30.9%) were compliant at 3-month evaluation. Questionnaires demonstrated fatigue in 34 (50%) and daytime sleepiness in 21 (30.9%). In multivariate regression analysis, Scadding stage and FAS behave as predictors of Apnea-Hypopnea Index (AHI) severity while sleepiness and steroids weren't associated. FAS score (ΔFAS = 6.3; p = 0.001) and ESS score (ΔESS = 2.8; p = 0.005) improved after three months of CPAP. Conclusions: OSA is highly prevalent in patients affected by sarcoidosis. ESS questionnaire is not reliable for OSA screening and other pre-test probability tool should be evaluated in further studies. CPAP leads to a significative reduction of fatigue and daytime sleepiness at three-month. Further studies are needed to confirm the high prevalence of OSA in sarcoidosis and the positive role of CPAP in fatigue. (Sarcoidosis Vasc Diffuse Lung Dis 2020; 37 (2): 169-178).


Assuntos
Pressão Positiva Contínua nas Vias Aéreas , Fadiga/prevenção & controle , Pulmão/fisiopatologia , Respiração , Sarcoidose/epidemiologia , Apneia Obstrutiva do Sono/terapia , Transtornos do Sono-Vigília/prevenção & controle , Sono , Idoso , Pressão Positiva Contínua nas Vias Aéreas/efeitos adversos , Fadiga/diagnóstico , Fadiga/epidemiologia , Fadiga/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Prospectivos , Recuperação de Função Fisiológica , Fatores de Risco , Roma/epidemiologia , Sarcoidose/diagnóstico , Sarcoidose/fisiopatologia , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/epidemiologia , Apneia Obstrutiva do Sono/fisiopatologia , Transtornos do Sono-Vigília/diagnóstico , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/fisiopatologia , Fatores de Tempo , Resultado do Tratamento
5.
Science ; 370(6512): 50-56, 2020 10 02.
Artigo em Inglês | MEDLINE | ID: mdl-33004510

RESUMO

Sleep is evolutionarily conserved across all species, and impaired sleep is a common trait of the diseased brain. Sleep quality decreases as we age, and disruption of the regular sleep architecture is a frequent antecedent to the onset of dementia in neurodegenerative diseases. The glymphatic system, which clears the brain of protein waste products, is mostly active during sleep. Yet the glymphatic system degrades with age, suggesting a causal relationship between sleep disturbance and symptomatic progression in the neurodegenerative dementias. The ties that bind sleep, aging, glymphatic clearance, and protein aggregation have shed new light on the pathogenesis of a broad range of neurodegenerative diseases, for which glymphatic failure may constitute a therapeutically targetable final common pathway.


Assuntos
Doença de Alzheimer/etiologia , Sistema Glinfático/fisiopatologia , Transtornos do Sono-Vigília/complicações , Sono , Envelhecimento , Doença de Alzheimer/fisiopatologia , Animais , Aquaporina 4/genética , Doenças Cardiovasculares/etiologia , Humanos , Sistema Linfático/fisiopatologia , Camundongos , Polimorfismo Genético , Proteínas Priônicas/metabolismo , Agregados Proteicos , Transtornos do Sono-Vigília/fisiopatologia
6.
Sci Total Environ ; 748: 141040, 2020 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-33113703

RESUMO

Noise and health guidance to date have focused on the direct links between noise and health outcomes such as annoyance, sleep disturbance, cardiovascular and metabolic disease, and cognitive impairment in schoolchildren. However, noise is a psychosocial stressor, and there are individual studies showing that exposure to noise or the self-reported responses to noise may affect health through interactions with the wider determinants of health and well-being including physical activity, use of green spaces and social interactions. Despite this emerging evidence concerning potential impacts of noise on the wider determinants of health, literature in the field remains dispersed and unsynthesised. This study seeks to synthetize evidence on different relationships between transportation noise, self-reported responses to noise and the wider determinants of health using a systematic review methodology. The search was conducted in Medline, PsycINFO, PubMed, and Scopus on articles published from 2000 to 2017. This led to the review of 76 papers which satisfied the inclusion criteria. Despite strong heterogeneity in the studies' methodologies and indicators used, there is some evidence that noise exposure and responses to noise such as annoyance and disturbance are associated with people's lifestyle, recreational activities as well as the local economy of the neighbourhood. On the other hand, there are some wider determinants of health, mainly those related to the built and natural environment, which modify the relationship between noise exposure and self-reported responses to noise. In particular, greenness, having access to quiet areas, and covering noise sources either visually or acoustically with natural features seems to decrease people's negative responses to noise. Results indicate that transportation noise has the potential to affect health through various pathways, and a holistic approach is needed to capture all the effects.


Assuntos
Ruído dos Transportes , Transtornos do Sono-Vigília , Criança , Meio Ambiente , Exposição Ambiental , Humanos , Ruído dos Transportes/efeitos adversos , Autorrelato
7.
Sleep Med Clin ; 15(3S): e1-e7, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33008491

RESUMO

Prior to the COVID-19 pandemic, few pediatric sleep medicine clinicians routinely engaged in telemedicine visits because thorough examinations were difficult to perform; there was lack of consistent reimbursement; and many clinicians were busy with their in-office practices. This article reviews how telemedicine has been explored in pediatric sleep medicine prior to the pandemic, current applications of telemedicine, challenges, and reimagining pediatric sleep within the realm of telemedicine.


Assuntos
Pediatria , Medicina do Sono , Transtornos do Sono-Vigília/diagnóstico , Transtornos do Sono-Vigília/terapia , Telemedicina/métodos , Betacoronavirus , Criança , Pressão Positiva Contínua nas Vias Aéreas , Infecções por Coronavirus , Humanos , Otolaringologia , Pandemias , Pneumonia Viral , Polissonografia , Encaminhamento e Consulta , Síndrome das Pernas Inquietas/diagnóstico , Síndrome das Pernas Inquietas/terapia , Sono , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/terapia , Transtornos do Sono do Ritmo Circadiano/diagnóstico , Transtornos do Sono do Ritmo Circadiano/terapia , Distúrbios do Início e da Manutenção do Sono/diagnóstico , Distúrbios do Início e da Manutenção do Sono/terapia
8.
Biol Sex Differ ; 11(1): 56, 2020 10 13.
Artigo em Inglês | MEDLINE | ID: mdl-33050941

RESUMO

BACKGROUND: COVID-19 and home isolation has impacted quality of life, but the perceived impact on anxiety and sleep remains equivocal. The purpose of this study was to assess the impact of COVID-19 and stay-at-home orders on self-report anxiety and sleep quality, with a focus on sex differences. We hypothesized that the COVID-19 pandemic would be associated with increased anxiety and decreased sleep quality, with stronger associations in women. METHODS: One hundred three participants (61 female, 38 ± 1 years) reported perceived changes in anxiety and sleep quality due to stay-at-home orders during the COVID-19 pandemic and were administered the Spielberger State-Trait Anxiety Inventory (STAI), Pittsburgh Sleep Quality Index (PSQI), and Insomnia Severity Index (ISI). Chi-square and T test analyses were utilized to assess sex differences in reported anxiety and sleep. Analysis of covariance was used to compare the associations between reported impact of COVID-19 and anxiety/sleep parameters. RESULTS: Women (80.3%) reported higher prevalence of increased general anxiety due to COVID-19 when compared to men (50%; p = 0.001) and elevated STAI state anxiety compared to men (43 ± 1 vs. 38 ± 1 a.u., p = 0.007). Despite these differences in anxiety, the perceived impact of COVID-19 on PSQI was not different between sexes. However, when stratified by perceived changes in anxiety due to COVID-19, participants with higher anxiety responses to COVID-19 had higher ISI compared to those with no perceived changes in anxiety (9 ± 1 vs. 5 ± 1 a.u., p = 0.003). Additionally, participants who reported reduced sleep quality due to COVID-19 reported higher state anxiety (45 ± 1 a.u.) compared to those that perceived no change (36 ± 2 a.u., p = 0.002) or increased (36 ± 2 a.u., p < 0.001) sleep quality. CONCLUSION: COVID-19 and state-ordered home isolation was associated with higher anxiety and reduced sleep quality, with a stronger association in women with respect to anxiety.


Assuntos
Transtornos de Ansiedade/epidemiologia , Transtornos de Ansiedade/psicologia , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/psicologia , Pneumonia Viral/epidemiologia , Pneumonia Viral/psicologia , Quarentena/psicologia , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/psicologia , Adolescente , Adulto , Idoso , Transtornos de Ansiedade/etiologia , Betacoronavirus/isolamento & purificação , Infecções por Coronavirus/prevenção & controle , Infecções por Coronavirus/transmissão , Feminino , Humanos , Estilo de Vida , Masculino , Pessoa de Meia-Idade , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Pneumonia Viral/transmissão , Prevalência , Qualidade de Vida , Autorrelato , Fatores Sexuais , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/virologia , Estados Unidos/epidemiologia , Adulto Jovem
9.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 4294-4297, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018945

RESUMO

Sleep disturbance and deprivation are major factors in delayed recovery, which can affect both the physical and emotional well-being of patients. Patients hospitalized in the Intensive Care Unit (ICU) are especially vulnerable to sleep deprivation due to light-induced disturbances. A desirable lighting intervention in the ICU would minimize light-induced disturbances while simultaneously providing feedback for the staff on when to perform patient care activities that require high intensity lighting. To this end, we performed a first phase testing for a biometrics-integrated lighting system that serves a dual function of sleep initiation and maintenance to improve the patient's quality of sleep. Preliminary findings are presented as a case study to assess the feasibility of scaling up the experimental model. While findings point to additional testing being necessary to determine whether the lighting system will be effective, the experiment detailed in this report establishes a starting paradigm upon which to base further investigation.Clinical Relevance- A biometrics-integrated lighting system that can improve sleep quality of the patient will not only reduce cost of care for the patients, but also increase the level of satisfaction for both patients and the hospital staff.


Assuntos
Iluminação , Transtornos do Sono-Vigília , Eletroencefalografia , Humanos , Unidades de Terapia Intensiva , Sono
10.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 4326-4329, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018953

RESUMO

Parkinson's Disease (PD) is the second most common neurodegenerative disorder with the non-motor symptoms preceding the motor impairment that is needed for clinical diagnosis. In the current study, an angle-based analysis that processes activity data during sleep from a smartwatch for quantification of sleep quality, when applied on controls and PD patients, is proposed. Initially, changes in their arm angle due to activity are captured from the smartwatch triaxial accelerometry data and used for the estimation of the corresponding binary state (awake/sleep). Then, sleep metrics (i.e., sleep efficiency index, total sleep time, sleep fragmentation index, sleep onset latency, and wake after sleep onset) are computed and used for the discrimination between controls and PD patients. A process of validation of the proposed approach when compared with the PSG-based ground truth in an in-the-clinic setting, resulted in comparable state estimation. Moreover, data from 15 early PD patients and 11 healthy controls were used as a test set, including 1,376 valid sleep recordings in-the-wild setting. The univariate analysis of the extracted sleep metrics achieved up to 0.77 AUC in early PD patients vs. healthy controls classification and exhibited a statistically significant correlation (up to 0.46) with the clinical PD Sleep Scale 2 counterpart Items. The findings of the proposed method show the potentiality to capture non-motor behavior from users' nocturnal activity to detect PD in the early stage.


Assuntos
Doença de Parkinson , Transtornos do Sono-Vigília , Humanos , Doença de Parkinson/diagnóstico , Polissonografia , Sono , Privação do Sono , Transtornos do Sono-Vigília/diagnóstico
11.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 4982-4985, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33019105

RESUMO

Sleep disorders are extremely common in today's society and are greatly affecting the health and safety of every person suffering from one. Over the last decades, Automatic Sleep Stage Classification (ASSC) systems have been developed to assist specialists in the sleep stage scoring process and therefore in the diagnosis of sleep disorders. Binaural beats are auditory phenomena that have been shown to have a positive impact in sleep quality and mental state. This paper introduces a framework that combines an ASSC system and a binaural beats generator in real time. Our goal is to pave the way for developing systems which could reproduce specific binaural beats depending on the detected sleep stage, in order to entrain the brain into a more efficient sleep. For the ASSC stage, different classifiers were evaluated using data signals retrieved from a public sleep stage signals database, corresponding to ten subjects. The complete framework was tested using the database signals and signals from a test subject, captured and processed in real time. Our proposed framework may lead to a fully automated system to improve sleep quality without the need of medication.


Assuntos
Fases do Sono , Transtornos do Sono-Vigília , Bases de Dados Factuais , Humanos , Polissonografia , Transtornos do Sono-Vigília/diagnóstico
12.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 5450-5454, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33019213

RESUMO

Sleep has been shown to be an indispensable and important component of patients' recovery process. Nonetheless, the sleep quality of patients in the Intensive Care Unit (ICU) is often low, due to factors such as noise, pain, and frequent nursing care activities. Frequent sleep disruptions by the medical staff and/or visitors at certain times might lead to disruption of the patient's sleep-wake cycle and can also impact the severity of pain. Examining the association between sleep quality and frequent visitation has been difficult, due to the lack of automated methods for visitation detection. In this study, we recruited 38 patients to automatically assess visitation frequency from captured video frames. We used the DensePose R-CNN (ResNet-101) model to calculate the number of people in the room in a video frame. We examined when patients are interrupted the most, and we examined the association between frequent disruptions and patient outcomes on pain and length of stay.Clinical Relevance- This study shows that rest disruptions can be automatically detected in the ICU, and such information can be used to better understand the sleep quality of patients in the ICU.


Assuntos
Estado Terminal , Transtornos do Sono-Vigília , Humanos , Unidades de Terapia Intensiva , Descanso , Sono
13.
Zh Nevrol Psikhiatr Im S S Korsakova ; 120(9. Vyp. 2): 6-12, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33076639

RESUMO

Changes in innate and adaptive immunity depending on sleep state and the influence of prolonged and restricted sleep time on morbidity and mortality as well as vulnerability to infections and effect of vaccination are discussed. Patients with insomnia have compromised immunity that could be reversed with the successful treatment of disordered sleep.


Assuntos
Distúrbios do Início e da Manutenção do Sono , Transtornos do Sono-Vigília , Humanos , Imunidade , Sono
14.
Zh Nevrol Psikhiatr Im S S Korsakova ; 120(9. Vyp. 2): 26-33, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33076642

RESUMO

OBJECTIVE: To describe the changes in temporal characteristics of sleep-wake cycle, which can serve as non-motor manifestations of an early stage of Parkinson's disease (PD), using the model of preclinical PD in rats of two age groups. MATERIAL AND METHODS: A prolonged (up to 21 days) model of preclinical PD in middle-aged (7-8 month) and aged (19-20 month) rats was created. The model was based on cumulative inhibition of proteasomal system of the brain caused by intranasal administration of lactacystin, a specific proteasome inhibitor. Polysomnographic data were recorded daily using telemetric Dataquest A.R.T. System (DSI, USA) in unrestrained animals. RESULTS AND CONCLUSION: Aging was accompanied with increased sleepiness during the active (dark) phase of the day (as was implied by a two-fold increase in the total time of drowsiness) and with 1.5-fold growth of light sleep during the inactive phase of the day. A common feature of sleep disturbances in the model of preclinical PD in both middle-aged and aged rats was hypersomnia during the active phase of the day. It was suggested to be similar to the excessive daytime sleepiness in humans. Hypersomnolence was more pronounced in aged rats because it added to sleepiness developing with aging. In both age groups, the model of preclinical PD was also associated with a decrease in EEG delta power during slow-wave sleep. It is considered dangerous because it might represent the decrease in protein synthesis rate and the weakening of restorative processes in neurons, occurring with the prolonged inhibition of proteasomal system of the brain. Sleep disturbances, identified the model of preclinical PD in rats of different age, may be recommended for clinical validation as low-cost early signs indicating the initial stage of PD.


Assuntos
Distúrbios do Sono por Sonolência Excessiva , Doença de Parkinson , Transtornos do Sono-Vigília , Animais , Humanos , Pessoa de Meia-Idade , Neurônios , Ratos , Transtornos do Sono-Vigília/etiologia , Vigília
15.
Zh Nevrol Psikhiatr Im S S Korsakova ; 120(9. Vyp. 2): 34-39, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33076643

RESUMO

OBJECTIVE: To validate the Scale of Behavioral Factors of Sleep Disturbances is people without diagnosed sleep disorders, as well as to reveal direct and indirect effects of sleep behavior on subjective sleep quality and well-being. MATERIAL AND METHODS: Sample 1 included 66 people, aged 19-55 years, without diagnosed sleep disturbances who completed the Scale of Behavioral Factors of Sleep Disturbances (subscales for Taking Medications and Non-Medications, Alcohol, Tonic Drinks and Using Gadgets in the evening, Delaying Bedtime, Self-Limitations, Sleep Ritual, Adherence to the Regimen, Postponement of the Morning Rise), Insomnia Severity Index, Hospital Scale of Anxiety and Depression. Sample 2 included 174 people, aged 17-57 years, without diagnosed sleep disorders, who completed Beck's Anxiety and Depression Inventories in addition to the scales administered to sample 1. Forty-four people completed the Scale of Behavioral Factors again after two weeks. RESULTS: The moderate reliability-consistency (α=0.62-0.93) and retest reliability of the subscales (r=0.33-0.79, p<0.01) as well as the relationship between poor sleep, especially in the evening, self-limitating behavior and sleep-related complaints of sleep, anxiety and, to a lesser extent, complaints of depressive symptoms (r=0.15-0.58, p<0.05) were revealed. All behavioral strategies, except for the sleep ritual, are characterized by an indirect effect on anxiety, depressiveness, poor well-being (|ß|=0.03-0.24): the more often a person uses them, the more likely he/she has sleep-related complaints, which, in turn, is a risk factor for poorer well-being. Self-limiting behavior and delaying the morning rise are associated with a lower level of well-being, even in the absence of sleep-related complaints (ß=0.23-0.34, p<0.01). CONCLUSIONS: The Scale of Behavioral Factors of Sleep Disturbances can be used for research purposes. The results of the study suggest that the dysfunctional role of behavior on well-being is predominantly indirect (through the perpetuation of complaints), but it can also be direct (regardless of complaints of sleep disorders).


Assuntos
Distúrbios do Início e da Manutenção do Sono , Transtornos do Sono-Vigília , Adolescente , Adulto , Transtornos de Ansiedade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Sono , Distúrbios do Início e da Manutenção do Sono/etiologia , Transtornos do Sono-Vigília/etiologia , Adulto Jovem
16.
Zh Nevrol Psikhiatr Im S S Korsakova ; 120(9. Vyp. 2): 55-61, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33076646

RESUMO

Sleep disturbance in pre-school and elementary school children is a common clinical situation. These disturbances may require pharmacotherapeutic approaches in certain cases. Major forms of sleep disturbances in children and data on known pharmacotherapeutic means of their corrections are considered.


Assuntos
Transtornos do Sono-Vigília , Criança , Pré-Escolar , Humanos , Transtornos do Sono-Vigília/tratamento farmacológico
17.
Zh Nevrol Psikhiatr Im S S Korsakova ; 120(9. Vyp. 2): 62-67, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33076647

RESUMO

Behavioral insomnia is the most common sleep disorder in young children. It significantly reduces the quality of parent's life and is one of the common complaints to a pediatrician or neurologist. The basis treatment of childhood insomnia is behavioral therapy, which includes sleep hygiene, age-appropriate daily routine and sleep associations, stable bedtime routines, positive reinforcement, bedtime fading, scheduled awakenings. Although a systematic ignoring («crying it out¼) is effective and widely used in behavioral therapy, it has low compliance and its safety is insufficiently studied. Therefore, a systematic ignoring is not a priority method of behavioral therapy and should not be used in children under 6 months of age. Behavioral therapy of childhood insomnia is complemented by psychological and informational support from parents, and in some cases, drug therapy. Prevention includes education of expectant parents on baby sleep hygiene.


Assuntos
Distúrbios do Início e da Manutenção do Sono , Transtornos do Sono-Vigília , Terapia Comportamental , Criança , Pré-Escolar , Humanos , Lactente , Sono , Higiene do Sono , Distúrbios do Início e da Manutenção do Sono/diagnóstico , Distúrbios do Início e da Manutenção do Sono/terapia
18.
Zh Nevrol Psikhiatr Im S S Korsakova ; 120(9. Vyp. 2): 68-73, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33076648

RESUMO

OBJECTIVE: To summarize published data on the prevalence, characteristics and diagnostic criteria of sleep disorders in epilepsy. MATERIAL AND METHODS: A search of published articles was performed in Medline (Pubmed), Scopus, Web of Science and e-library databases. RESULTS: Epidemiologic, clinical and diagnostic aspects of excessive daytime sleepiness, obstructive sleep apnea and central apnea, restless leg syndrome and parasomnias related to slow-wave and REM-sleep in patients with epilepsy were analyzed. CONCLUSIONS: Further studies are needed to gain an insight into the complex associations of sleep disorders in epilepsy to optimize diagnostic and treatment approaches and to improve the quality of life in that patient population.


Assuntos
Epilepsia , Parassonias , Transtornos do Sono-Vigília , Epilepsia/diagnóstico , Epilepsia/epidemiologia , Humanos , Parassonias/diagnóstico , Parassonias/epidemiologia , Qualidade de Vida , Sono , Transtornos do Sono-Vigília/diagnóstico , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/etiologia
19.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 3452-3455, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018746

RESUMO

Sleep disorder is one of many neurological diseases that can affect greatly the quality of daily life. It is very burdensome to manually classify the sleep stages to detect sleep disorders. Therefore, the automatic sleep stage classification techniques are needed. However, the previous automatic sleep scoring methods using raw signals are still low classification performance. In this study, we proposed an end-to-end automatic sleep staging framework based on optimal spectral-temporal sleep features using a sleep-edf dataset. The input data were modified using a bandpass filter and then applied to a convolutional neural network model. For five sleep stage classification, the classification performance 85.6% and 91.1% using the raw input data and the proposed input, respectively. This result also shows the highest performance compared to conventional studies using the same dataset. The proposed framework has shown high performance by using optimal features associated with each sleep stage, which may help to find new features in the automatic sleep stage method.Clinical Relevance- The proposed framework would help to diagnose sleep disorders such as insomnia by improving sleep stage classification performance.


Assuntos
Eletroencefalografia , Transtornos do Sono-Vigília , Humanos , Redes Neurais de Computação , Sono , Fases do Sono
20.
Artigo em Russo | MEDLINE | ID: mdl-33081442

RESUMO

OBJECTIVE: To study symptoms of neurotic disorders and social masochism in chemical addicts. MATERIAL AND METHODS: Thirty outpatients of the Novosibirsk Regional Clinical Addiction Dispensary were studied. Corresponding scales and questionnaires, along with a social masochism questionnaire developed by the authors, were used. Results were compared to those of 25 healthy people. RESULTS AND CONCLUSION: A significantly higher level (p≤0.05) of the following neurotic disorders: sleep disturbances, hysterical neurotic disorder, anxious neurotic disorder, social maladaptation and depressive neurotic disorder as well as a subclinical level of anxiety and depression were observed in chemical addicts. Moreover, patients with chemical dependence revealed significantly higher (p≤0.05) indicators of aggression, victim behavior and social masochism (different types of aggression, victimization, irritability, negativism, resentment, guilt, self-harming behavior, hypersocial behavior, provoking and uncritical behavior, the role of the victim, negative perception and a general indicator of social masochism). The correlations between indicators of the affective sphere, manifestations of social masochism and neurotic disorders in individuals with chemical dependence were identified.


Assuntos
Transtornos Neuróticos , Transtornos do Sono-Vigília , Transtornos de Ansiedade , Humanos , Masoquismo , Pacientes Ambulatoriais
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