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1.
Complement Ther Clin Pract ; 39: 101132, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32379667

RESUMO

BACKGROUND: Patients with Coronavirus Disease 2019(COVID-19) will experience high levels of anxiety and low sleep quality due to isolation treatment. Some sleep-improving drugs may inhibit the respiratory system and worsen the condition. Prolonged bedside instruction may increase the risk of medical infections. OBJECTIVE: To investigate the effect of progressive muscle relaxation on anxiety and sleep quality of COVID-19. METHODS: In this randomized controlled clinical trial, a total of 51 patients who entered the isolation ward were included in the study and randomly divided into experimental and control groups. The experimental group used progressive muscle relaxation (PMR) technology for 30 min per day for 5 consecutive days. During this period, the control group received only routine care and treatment. Before and after the intervention, the Spielberger State-Trait Anxiety Scale (STAI) and Sleep State Self-Rating Scale (SRSS) were used to measure and record patient anxiety and sleep quality. Finally, data analysis was performed using SPSS 25.0 software. RESULTS: The average anxiety score (STAI) before intervention was not statistically significant (P = 0.730), and the average anxiety score after intervention was statistically significant (P < 0.001). The average sleep quality score (SRSS) of the two groups before intervention was not statistically significant (P = 0.838), and it was statistically significant after intervention (P < 0.001). CONCLUSION: Progressive muscle relaxation as an auxiliary method can reduce anxiety and improve sleep quality in patients with COVID-19.


Assuntos
Ansiedade , Infecções por Coronavirus , Pandemias , Pneumonia Viral , Terapia de Relaxamento , Transtornos do Sono-Vigília , Adulto , Ansiedade/terapia , Transtornos de Ansiedade , Treinamento Autógeno , Betacoronavirus , Infecções por Coronavirus/complicações , Infecções por Coronavirus/psicologia , Feminino , Humanos , Masculino , Relaxamento Muscular , Pneumonia Viral/complicações , Pneumonia Viral/psicologia , Terapia de Relaxamento/métodos , Sono/fisiologia , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/terapia
2.
Br J Nurs ; 29(5): 298-302, 2020 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-32167811

RESUMO

Sleep disturbance is common in patients in the intensive care unit (ICU). Numerous factors can contribute to this. High noise and light levels, nursing interventions and medication administration are major factors. This study investigated the demographic and environmental factors that might adversely affect ICU patients' quality of sleep. Data were collected from 103 patients using a demographic data sheet, the Freedman Quality of Sleep Scale and the Richards-Campbell Sleep Scale. Patients' demographic characteristics were found to have no significant effects on their perceived quality of sleep. Environmental factors, including noise, light, nursing interventions, diagnostic testing, the administration of medication, talking and phones ringing, were significantly related to the patients' perceived quality of sleep.


Assuntos
Unidades de Terapia Intensiva/estatística & dados numéricos , Ruído/efeitos adversos , Transtornos do Sono-Vigília/epidemiologia , Adulto , Cuidados Críticos , Estudos Transversais , Meio Ambiente , Feminino , Humanos , Jordânia , Masculino , Sono/fisiologia , Privação do Sono , Transtornos do Sono-Vigília/etiologia
3.
PLoS One ; 15(2): e0228533, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32053609

RESUMO

This systematic review and meta-analysis examines the associations of allergic rhinitis with sleep duration and sleep impairment. Observational studies published before August 2019 were obtained through English language literature searches in the PubMed, Embase, and CINAHL databases. Mean differences and odds ratios with 95% confidence intervals were extracted and used for meta-analysis. Heterogeneity was confirmed by the I2-heterogeneity test. Subgroup analysis was conducted to evaluate the influence of study design. The Grading of Recommendations Assessment, Development, and Evaluation approach was used to determine the level of evidence. In total, 2544 records were identified through database searches; 914 duplicate records were excluded, 1452 records were removed after screening of titles and abstracts, 151 records were excluded after full-text screening, and 27 articles were included in the final meta-analyses. A total of 240,706,026 patients (19,444,043 with allergic rhinitis) were considered. No significant difference in sleep duration between the allergic rhinitis and the control groups was found. Patients with allergic rhinitis presented with significantly higher sleep quality scores, sleep disturbances scores, and sleep latency scores; more frequent use of sleep medications; and lower sleep efficiency as measured by the Pittsburgh Sleep Quality Index and polysomnography. Meta-analyses for adjusted odds ratios showed that allergic rhinitis was also associated with higher risks of nocturnal dysfunctions, including insomnia, nocturnal enuresis, restless sleep, sleep-disordered breathing, obstructive sleep apnea, and snoring. Meta-analysis for adjusted odds ratio also showed that allergic rhinitis was associated with daytime dysfunction, including difficulty waking up, daytime sleepiness, morning headache, and the use of sleep medications. The overall quality of evidence ranged from low to very low, indicating that caution is required when interpreting these results. This study demonstrates that there is a significant association of AR with sleep characteristics.


Assuntos
Rinite Alérgica/epidemiologia , Rinite Alérgica/fisiopatologia , Transtornos do Sono-Vigília/epidemiologia , Sono/fisiologia , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Humanos , Pessoa de Meia-Idade , Estudos Observacionais como Assunto/estatística & dados numéricos , Polissonografia , Qualidade de Vida , Rinite Alérgica/complicações , Síndromes da Apneia do Sono/diagnóstico , Síndromes da Apneia do Sono/epidemiologia , Síndromes da Apneia do Sono/etiologia , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/epidemiologia , Apneia Obstrutiva do Sono/etiologia , Transtornos do Sono-Vigília/diagnóstico , Transtornos do Sono-Vigília/etiologia , Ronco/diagnóstico , Ronco/epidemiologia , Ronco/etiologia , Adulto Jovem
4.
PLoS One ; 15(2): e0228853, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32059015

RESUMO

Dust and fumes are complex mixtures of airborne gases and fine particles present in all environments inhabited by people. This study investigated the relationship between occupational dust exposure levels and mental health problems such as depression or anxiety, fatigue, and insomnia or sleep disturbance. We analyzed data from the third and fourth Korean Working Conditions Survey (KWCS) conducted by the Korea Occupational Safety and Health Agency in 2011 and 2014. We performed chi-square tests to compare the different baseline and occupational characteristics and mental health status according to occupational dust exposure levels. The odds ratio (OR) and 95% confidence intervals (95% CIs) for mental health symptoms (fatigue, depression or anxiety, and insomnia or sleep disturbance) were calculated using adjusted multiple logistic regression models. A total of 78,512 participants (43,979 in men, 34,533 in women) were included in this study. Among them, 6,013 (7.7%) and 2,625 (3.3%) reported "moderate" and "severe" dust exposure, respectively. Among those who answered "yes" to depression or anxiety, fatigue, insomnia or sleep disturbance, 50 (4.6%), 961 (4.8%), and 123 (5.9%), respectively, demonstrated "severe" occupational dust exposure. Compared to "low" levels of dust exposure, "moderate" and "severe" exposure increased the risk of depression and anxiety (OR = 1.09, 95%CI: 0.88-1.36; OR = 1.16, 95%CI: 0.87-1.58, per exposure respectively); however, this was not statistically significant. For fatigue, significance was observed for "moderate" 1.54 (1.46-1.64) and "severe" 1.65 (1.52-1.80) exposure levels. "Severe" levels increased the risk of insomnia or sleep disturbance (OR = 1.52, 95%CI: 1.25-1.85). These results suggest that the "dust annoyance" concept of mental health, which may be explained by a neurocognitive mechanism, is plausible. Occupational "dust annoyance" has been linked to workers' mental health status, particularly in terms of fatigue and sleep disturbance; a dose-response relationship has been observed. Workers should be protected against dust to support their health and productivity.


Assuntos
Poeira/análise , Saúde Mental , Exposição Ocupacional/efeitos adversos , Adulto , Idoso , Ansiedade/epidemiologia , Ansiedade/etiologia , Depressão/epidemiologia , Depressão/etiologia , Fadiga/epidemiologia , Fadiga/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/epidemiologia , Doenças Profissionais/etiologia , Exposição Ocupacional/análise , Saúde do Trabalhador , Razão de Chances , República da Coreia/epidemiologia , Distúrbios do Início e da Manutenção do Sono/epidemiologia , Distúrbios do Início e da Manutenção do Sono/etiologia , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/etiologia , Inquéritos e Questionários , Adulto Jovem
5.
Ann Allergy Asthma Immunol ; 124(4): 385-392, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-31923547

RESUMO

BACKGROUND: Atopic dermatitis (AD) is a common childhood disorder that is associated with a variety of negative health outcomes in children and parents, including poor sleep and daytime functioning. Despite this, few studies have examined the impact of treatment for AD on sleep, and even fewer have included validated sleep questionnaires, child report of sleep disturbance, or objective measures of sleep. OBJECTIVE: To address limitations in the literature by examining objective and subjective reports of sleep, as well as measures of daytime functioning before and after admission to an intensive treatment program for AD. METHODS: Twenty-nine parent-child dyads who presented to an intensive day treatment program participated in this study. Sleep was objectively measured with 1 week of actigraphy both 1 week before admission and 1 month after discharge. Subjective questionnaires of sleep, daytime functioning, and quality of life were completed by children and parents at admission, discharge, 1 month after discharge, and 3 months after discharge. RESULTS: Study results highlight the benefit of the treatment program on reducing AD severity, as well as improvements in objectively measured sleep duration and efficiency, self-reported measures of sleep, daytime functioning, and quality of life in children and parents up to 3 months after discharge. CONCLUSION: This study highlights the importance of treatment for child AD on both child and parent health outcomes.


Assuntos
Antialérgicos/uso terapêutico , Dermatite Atópica/complicações , Qualidade de Vida , Transtornos do Sono-Vigília/etiologia , Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pais , Sono
6.
Neurology ; 94(7): e705-e717, 2020 02 18.
Artigo em Inglês | MEDLINE | ID: mdl-31964693

RESUMO

OBJECTIVE: A cross-sectional study was performed to evaluate whether quantitative oculomotor measures correlate with disease severity in late-onset GM2 gangliosidosis (LOGG) and assess cognition and sleep as potential early nonmotor features. METHODS: Ten patients with LOGG underwent quantitative oculomotor recordings, including measurements of the angular vestibulo-ocular reflex (VOR), with results compared to age- and sex-matched controls. Disease severity was assessed by ataxia rating scales. Cognitive/neuropsychiatric features were assessed by the cerebellar cognitive affective syndrome (CCAS) scale, Cerebellar Neuropsychiatric Rating Scale, and sleep quality evaluated using subjective sleep scales. RESULTS: Oculomotor abnormalities were found in all participants, including 3/10 with clinically normal eye movements. Abnormalities involved impaired saccadic accuracy (5/10), abnormal vertical (8/10) and horizontal (4/10) pursuit, reduced optokinetic nystagmus (OKN) responses (7/10), low VOR gain (10/10), and impaired VOR cancellation (2/10). Compared to controls, the LOGG group showed significant differences in saccade, VOR, OKN, and visually enhanced VOR gains. Severity of saccadic dysmetria, OKN, and VOR fixation-suppression impairments correlated with ataxia scales (p < 0.05). Nine out of ten patients with LOGG had evidence of the CCAS (5/10 definite, 2/10 probable, 2/10 possible). Excessive daytime sleepiness was present in 4/10 and 8/10 had poor subjective sleep quality. CONCLUSIONS: Cerebellar oculomotor abnormalities were present in all patients with LOGG, including those with normal clinical oculomotor examinations. Saccade accuracy (dorsal cerebellar vermis localization), fixation suppression, and OKN gain (cerebellar flocculus/paraflocculus localization) correlated with disease severity, suggesting that quantitative oculomotor measurements could be used to track disease progression. We found evidence of the CCAS, suggesting that cerebellar dysfunction may explain the cognitive disorder in LOGG. Sleep impairments were prevalent and require further study.


Assuntos
Movimentos Oculares , Gangliosidoses GM2/diagnóstico , Adulto , Encéfalo/diagnóstico por imagem , Cognição , Estudos de Coortes , Estudos Transversais , Feminino , Gangliosidoses GM2/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Transtornos da Motilidade Ocular/diagnóstico , Transtornos da Motilidade Ocular/etiologia , Transtornos da Motilidade Ocular/fisiopatologia , Escalas de Graduação Psiquiátrica , Índice de Gravidade de Doença , Sono , Transtornos do Sono-Vigília/diagnóstico , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/fisiopatologia
7.
Pediatrics ; 145(2)2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31964760

RESUMO

Pediatricians regularly care for children who have experienced child maltreatment. Child maltreatment is a risk factor for a broad range of mental health problems. Issues specific to child maltreatment make addressing emotional and behavioral challenges among maltreated children difficult. This clinical report focuses on 2 key issues necessary for the care of maltreated children and adolescents in pediatric settings: trauma-informed assessments and the role of pharmacotherapy in maltreated children and adolescents. Specific to assessment, current or past involvement of the child in the child welfare system can hinder obtaining necessary information or access to appropriate treatments. Furthermore, trauma-informed assessments can help identify the need for specific interventions. Finally, it is important to take both child welfare system and trauma-informed assessment approaches into account when considering the use of psychotropic agents because there are critical diagnostic and systemic issues that affect the prescribing and discontinuing of psychiatric medications among children with a history of child maltreatment.


Assuntos
Maus-Tratos Infantis/psicologia , Serviços de Proteção Infantil , Transtornos Mentais/tratamento farmacológico , Psicotrópicos/uso terapêutico , Adolescente , Ansiedade/etiologia , Ansiedade/terapia , Transtorno do Deficit de Atenção com Hiperatividade/diagnóstico , Transtorno do Deficit de Atenção com Hiperatividade/etiologia , Transtorno do Deficit de Atenção com Hiperatividade/terapia , Criança , Maus-Tratos Infantis/diagnóstico , Maus-Tratos Infantis/legislação & jurisprudência , Serviços de Proteção Infantil/legislação & jurisprudência , Bases de Dados Factuais , Depressão/etiologia , Depressão/terapia , Exposição à Violência/psicologia , Inquéritos Epidemiológicos , Humanos , Transtornos Mentais/diagnóstico , Transtornos Mentais/etiologia , Pediatras , Resiliência Psicológica , Transtornos do Sono-Vigília/etiologia , Determinantes Sociais da Saúde , Transtornos de Estresse Pós-Traumáticos/diagnóstico , Transtornos de Estresse Pós-Traumáticos/etiologia , Transtornos de Estresse Pós-Traumáticos/terapia , Suspensão de Tratamento
8.
Support Care Cancer ; 28(1): 261-269, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31037378

RESUMO

PURPOSE: Local/systemic symptoms during cancer therapy may be exacerbated by dysregulated inflammation and its downstream toxic effects. Minocycline can suppress proinflammatory cytokine release; therefore, we investigated its potential to reduce patient-reported symptom severity during radiotherapy (RT) for head and neck cancer (HNC). METHODS: Eligible patients for this blinded, placebo-controlled trial were adults with T0-3, N-any, and M0 HNC receiving single-modality RT. Participants were randomized 1:1 to either minocycline (200 mg/day) or placebo during RT. The primary endpoint was the area under the curve (AUC) of 5 prespecified symptoms (pain, fatigue, disturbed sleep, poor appetite, difficulty swallowing/chewing) during RT, assessed with the MD Anderson Symptom Inventory for HNC (MDASI-HN). RESULTS: We analyzed data from 20 evaluable patients per arm. Overall, 75% had oropharyngeal cancer and 78% were male. No grade 3+ adverse events potentially related to study medication were observed. Two minocycline patients required a feeding tube during RT vs 5 placebo patients (P = 0.21). The average daily AUC during RT for the 5 MDASI-HN symptoms was 3.1 (SD = 1.0) for minocycline and 3.7 (SD = 1.7) for placebo (P = 0.16); the 0.37 effect size was less than our 0.70 target. AUC comparisons for several individual symptoms and symptom interference favored minocycline but were not statistically significant. The greatest numerical differences occurred for systemic symptoms, larger toward treatment end, and in early post-RT recovery. CONCLUSIONS: Minocycline was feasible, well tolerated, and achieved a positive signal toward reducing patient-reported symptom severity during RT for HNC, particularly for systemic symptoms. This justifies additional study and informs future trial design.


Assuntos
Neoplasias de Cabeça e Pescoço/tratamento farmacológico , Neoplasias de Cabeça e Pescoço/radioterapia , Minociclina/uso terapêutico , Radiodermatite/prevenção & controle , Idoso , Terapia Combinada , Transtornos de Deglutição/epidemiologia , Transtornos de Deglutição/etiologia , Fadiga/epidemiologia , Fadiga/etiologia , Feminino , Neoplasias de Cabeça e Pescoço/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Dor/epidemiologia , Dor/etiologia , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/etiologia , Resultado do Tratamento
9.
Am J Otolaryngol ; 41(1): 102283, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31526628

RESUMO

BACKGROUND: The impact of simple snoring on sleep structure and sleepiness has not been well described. In several studies, self-reported snoring was associated with increased daytime sleepiness. However, most studies did not distinguish patients with simple snoring from those with coexisting obstructive sleep apnea (OSA) using objective measures. We therefore evaluated the relationship between objectively measured snoring and both sleep structure and daytime sleepiness in patients with no or mild OSA. METHODS: Subjects referred for suspected sleep disorders underwent polysomnography (PSG) during which breath sounds were recorded by a microphone. Those with an apnea-hypopnea index (AHI) <15/h were analyzed. Individual snores were identified by a computer algorithm, from which the snore index (SI) was calculated as the number of snores/h of sleep. Sleep stages and arousals were quantified. Daytime sleepiness was evaluated using the Epworth Sleepiness Scale (ESS) score. RESULTS: 74 (35 males) subjects were included (age, mean ±â€¯SD: 46.4 ±â€¯15.3 years and body mass index: 29.8 ±â€¯7.0 kg/m2). The mean SI was 266 ±â€¯243 snores/h. Subjects were categorized according to their SI into 3 tertiles: SI < 100, between 100-350, and >350. No sleep structure indeces, arousals, or ESS score differed among SI tertiles (p > 0.13). There was no correlation between SI and any of these variables (p > 0.29). In contrast, the AHI was significantly related to frequency of arousals (r = 0.23, p = 0.048). CONCLUSIONS: These findings suggest that simple snoring assessed objectively is not related to indices of sleep structure or subjective sleepiness.


Assuntos
Transtornos do Sono-Vigília/etiologia , Ronco/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Polissonografia , Fatores de Risco
10.
Support Care Cancer ; 28(1): 351-360, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31049671

RESUMO

PURPOSE: This study aimed to explore the possible range of change of a single-session music intervention (SMI) on symptom clusters and neurological reactivity for women with breast cancer undergoing chemotherapy. METHODS: A parallel and randomized, controlled study with repeated measures design was used. A total of 100 women with breast cancer were randomly assigned to the SMI or a control group. The outcome measurements of symptom cluster were collected using the Multidimensional Fatigue Symptom Inventory, Pittsburgh Sleep Quality Index, the Hospital Anxiety and Depression Scale, and the neurological reactivity with heart rate variability at four time points: before commencement of the intervention (T0), immediately afterward (T1), 1 week later (T2), and 3 weeks after the intervention (T3). RESULTS: Of the 50 women in each group, 46 in the SMI and 48 in the control group completed the post-test at T3. Multivariate analysis of variance indicated that the SMI group had a medium effect in change of symptom clusters compared to the control group at T2. Moreover, after adjusting for baseline between normal and higher levels of sympathetic tone activity, significant differences existed in fatigue and depression at T2 and sleep disturbance at T3. CONCLUSIONS: A single-session music intervention can be effectively used to reduce symptom clusters for women with breast cancer. Targeting those who have a higher level of sympathetic tone activity is recommended.


Assuntos
Neoplasias da Mama/complicações , Neoplasias da Mama/terapia , Frequência Cardíaca/fisiologia , Musicoterapia/métodos , Adulto , Ansiedade/etiologia , Ansiedade/terapia , Doenças do Sistema Nervoso Autônomo/etiologia , Doenças do Sistema Nervoso Autônomo/terapia , Neoplasias da Mama/fisiopatologia , Neoplasias da Mama/psicologia , Depressão/etiologia , Depressão/terapia , Fadiga/etiologia , Fadiga/terapia , Feminino , Humanos , Pessoa de Meia-Idade , Música/psicologia , Autorrelato , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/terapia , Inquéritos e Questionários , Avaliação de Sintomas , Síndrome
11.
Zh Nevrol Psikhiatr Im S S Korsakova ; 119(9. Vyp. 2): 44-50, 2019.
Artigo em Russo | MEDLINE | ID: mdl-31825389

RESUMO

BACKGROUND: Excessive daytime sleepiness (DS) is a common symptom of Parkinson's disease (PD), which can occur at any stage of the disease and decrease the quality of life of patients. The relationship between excessive daytime sleepiness and Parkinson's disease is determined by neurodegenerative process in the brain structures. However, there are many other factors, which can contribute to this phenomenon. AIM: To assess the prevalence and causes of DS as well as its impact on the quality of life of patients. MATERIAL AND METHODS: Seventy patients (mean age 65.0±8.4 years) with PD, stage I-III, including 48 patients with DS and 22 without DS, were examined. All patients underwent clinical/neurological and neuropsychological examinations using a set of scales and polysomnography, if necessary. RESULTS AND CONCLUSION: Sleep disorders are the most frequent non-motor symptoms of PD. The prevalence of subjective DS is determined for the first time. The disassociation between subjective and objective DS is observed in 32,5% of patients. Clinical combinations of DS with other sleep disorders are described. Taking dopaminergic medication contributes significantly to the development of DS and affective disorders (anxiety, depression) play a role in subjective DS.


Assuntos
Distúrbios do Sono por Sonolência Excessiva , Doença de Parkinson , Transtornos do Sono-Vigília , Idoso , Distúrbios do Sono por Sonolência Excessiva/etiologia , Humanos , Pessoa de Meia-Idade , Doença de Parkinson/complicações , Polissonografia , Qualidade de Vida , Transtornos do Sono-Vigília/etiologia
12.
BMC Public Health ; 19(1): 1508, 2019 Nov 12.
Artigo em Inglês | MEDLINE | ID: mdl-31718590

RESUMO

BACKGROUND: Noise exposure is considered a stressor that may potentially exert negative health effects among the exposed individuals. On a population basis, the most prevalent and immediate response to noise is annoyance, which is an individually experienced phenomenon that may activate physiological stress-responses and result in both physical and mental symptoms. Health implications of traffic noise have been investigated thoroughly, but not of neighbour noise. The aim of the present study was to examine the associations between neighbour noise annoyance and eight different physical and mental health symptoms. METHODS: Cross-sectional data from the Danish Health and Morbidity Survey 2017 were used. The present study included a random sample of 3893 adults living in multi-storey housing. Information on neighbour noise annoyance and various health symptoms (e.g. pain in various body parts, headache, sleeping problems, depression, and anxiety) during the past two weeks was obtained by self-administered questionnaires. The question on neighbour noise annoyance and health symptoms, respectively, had three possible response options: 'Yes, very annoyed/bothered', 'Yes, slightly annoyed/bothered', 'No'. The associations between neighbour noise annoyance and very bothering physical and mental health symptoms were investigated using multiple logistic regression models. RESULTS: Being very annoyed by neighbour noise was significantly associated with higher odds of being very bothered by all eight health symptoms (adjusted OR = 1.73-3.32, all p-values < 0.05) compared to individuals not annoyed by noise from neighbours. Statistically significant interactions were observed between sex and two of the eight health symptoms. Among women, a strong association was observed between neighbour noise annoyance and being very bothered by pain or discomfort in the shoulder or neck, and in the arms, hands, legs, knees, hips or joints. Among men, no associations were observed. CONCLUSIONS: Based on the findings from this study, neighbour noise annoyance is strongly associated with eight different physical and mental health symptoms. Future studies are encouraged to 1) determine the direction of causality using a longitudinal design, 2) explore the biological mechanisms explaining the sex-specific impact of neighbour noise annoyance on symptoms of musculoskeletal pain or discomfort and the other outcomes as well.


Assuntos
Exposição Ambiental , Habitação , Ruído/efeitos adversos , Características de Residência , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Ansiedade/etiologia , Estudos Transversais , Dinamarca , Depressão/etiologia , Feminino , Cefaleia/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Ruído dos Transportes/efeitos adversos , Razão de Chances , Dor/etiologia , Fatores Sexuais , Transtornos do Sono-Vigília/etiologia , Inquéritos e Questionários , Adulto Jovem
13.
Best Pract Res Clin Rheumatol ; 33(3): 101434, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31703798

RESUMO

This review article discusses various forms of sleep disorders associated with musculoskeletal diseases (MD). It presents the pathophysiology and interaction of sleep-related disorders and MD and summarizes clinical symptoms and therapies from a somnological perspective. BACKGROUND: A large number of patients suffering from MD report fragmented sleep with poor overall sleep quality. Sleep disorders often lead to increased symptoms such as daytime fatigue, depression, or increased pain intensity. In contrast, the perception of pain worsens the quality of sleep. Sleep is a complex regulation of hormonal and neuromodulatory influences to maintain regenerative processes and signal processing. Furthermore, interleukins (e.g., IL-6 and TNFα), messenger substances, or inflammatory markers (e.g., CRP) may have a regulatory influence on sleep. THERAPY: Sleep disorders in MD can often be treated with behavioral therapies or drug approaches. Another and very important influence is physical activity. In combination with training, regular physical activity can lead, for instance, to improved sleep quality, endurance performance, and reduced inflammation values. The change of lifestyle with regard to activity and nutrition is another key concept in the optimal therapy of patients with MD.


Assuntos
Doenças Reumáticas/complicações , Transtornos do Sono-Vigília/etiologia , Humanos , Sono
14.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi ; 54(10): 754-759, 2019 Oct 07.
Artigo em Chinês | MEDLINE | ID: mdl-31606988

RESUMO

Objective: To explore the correlation between sleep and laryngopharyngeal reflux disease by epidemiological approaches. Methods: From May 1, 2017 to April 30, 2018, data of age, gender, height, weight, smoking, alcohol consumption, constipation and high fat diet in patients in Otorhinolaryngology specialist clinic, the Eighth Medical Center, General Hospital of the Chinese PLA were retrospectively analyzed. Reflux Symptom Index (RSI), Pittsburgh Sleep Quality Index (PSQI) and Hospital Anxiety and Depression Scale (HADS)were filled. According to RSI scores, patients were divided into case group and control group. The differences of the above indicators between the two groups were compared by Stata 12.0 software, and the risk factors of LPRD were analyzed by multivariate Logistic regression. Results: A total of 908 patients were enrolled, including 166 in the case group and 742 in the control group. There was no significant difference in BMI, smoking, drinking, constipation and high fat diet between the two groups (all P>0.05). The PSQI, anxiety and depression score of the case group were higher than those of the control group. The anxiety and depression scores of the patients with sleep disorders in the case group were significantly higher than those of the normal sleepers (all P<0.05). RSI of the patients with sleep disorders was higher than that of the patients with normal sleep(9.5[4.0,16.0]vs. 5.0[1.0,10.0], Z=-6.07, P<0.001). Multivariate analysis showed that sleep disorder was the risk factors of LPRD (OR=2.59, 95%CI 1.75-3.84). Conclusions: Sleep disorder is related to the occurrence of LPRD. The association between LPRD and sleep disturbances is bidirectional. Sleep disorder may also be related to the anxiety and depression in LPRD patients. Handling sleep disorder timely may benefit LPRD patients.


Assuntos
Refluxo Laringofaríngeo/complicações , Transtornos do Sono-Vigília/etiologia , Adulto , Ansiedade/complicações , Ansiedade/epidemiologia , China/epidemiologia , Depressão/complicações , Depressão/epidemiologia , Humanos , Refluxo Laringofaríngeo/epidemiologia , Refluxo Laringofaríngeo/psicologia , Estudos Retrospectivos , Fatores de Risco , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/psicologia
15.
Medicine (Baltimore) ; 98(41): e17464, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31593103

RESUMO

Osteoarthritis (OA) is a common condition of the hip. Patients with hip OA often report nocturnal pain, yet little is known how it affects sleep quality. The purpose of this paper was to assess how hip arthritis affects sleep quality. We hypothesized that hip pain caused by hip OA affects sleep quality in adult patients.This is a prospective, cross-sectional study of patients who were diagnosed with hip OA. Patients were evaluated using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), hip outcome score (HOS), and modified Harris hip score (mHHS). Sleep quality was assessed using Pittsburgh Sleep Quality Index (PSQI). A multiple regression model was used to assess factors associated with poor sleep quality.A total of 106 patients were analyzed. All patients had a Tonnis grade of 2 or 3 and American Society of Anesthesiologists (ASA) classification of 2. WOMAC, HOS, and mHHS were significantly and negatively correlated with PSQI. The multiple regression model, WOMAC, short form health survey vitality, ASA classification, and history of obstructive sleep apnea were associated with poor sleep quality (R = 0.60, P < .001).Patients with hip OA, who report a symptomatic hip, are susceptible to reduced sleep quality. There is a correlation between worsening HOSs and sleep quality. The WOMAC score is a significant predictor of poor sleep quality. Patients with poor hip metrics should be screened for sleep disturbance.


Assuntos
Artralgia/fisiopatologia , Osteoartrite do Quadril/fisiopatologia , Transtornos do Sono-Vigília/fisiopatologia , Sono , Adulto , Idoso , Idoso de 80 Anos ou mais , Artralgia/etiologia , Estudos Transversais , Feminino , Articulação do Quadril/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Osteoartrite do Quadril/complicações , Medição da Dor , Estudos Prospectivos , Transtornos do Sono-Vigília/etiologia , Adulto Jovem
16.
Artigo em Inglês | MEDLINE | ID: mdl-31547191

RESUMO

Recent contributions have reported sleep disorders as one of the health impairment outcomes of workaholism. A possible factor affecting the sleep-wake cycle might be the intensive use of smartphones. The current study aimed to explore the role of intensive smartphone use in the relationship between workaholism and the sleep-wake cycle. Two serial multiple mediation models were tested on a sample of 418 employees, who filled self-report questionnaires measuring workaholism, use of smartphones, sleep quality and daytime sleepiness, using conditional process analysis for testing direct and indirect effects. Results supported our hypotheses regarding two serial multiple mediation models-that intensive smartphone use and poor sleep quality mediated the relationship between workaholism and daytime sleepiness, and that smartphone use and daytime sleepiness mediated the relationship between workaholism and poor quality of sleep. Although the use of a cross-sectional design and the snowball technique for collecting data can be considered as possible limitations, the current study is one of the first to document the potential detrimental role of the intensive smartphone use on the workaholism-sleep disorders relationship.


Assuntos
Comportamento Aditivo/complicações , Transtornos do Sono-Vigília/etiologia , Smartphone , Trabalho/psicologia , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Autorrelato , Sono , Distúrbios do Início e da Manutenção do Sono , Inquéritos e Questionários , Adulto Jovem
17.
Artigo em Inglês | MEDLINE | ID: mdl-31505823

RESUMO

The impact of psychosocial factors on health has received increased attention. This study employed a multi-stage hierarchical cluster sampling method and a cross-sectional survey was conducted from March to August 2017. By studying 2116 oilfield workers based in Karamay, Xinjiang, the relationship between occupational stress, blood hormone levels, and sleep was analyzed. Occupational stress was measured using the internationally accepted Occupational Stress Inventory Revised Edition (OSI-R) questionnaire and sleep disorders were measured using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The study found that the sleep quality of respondents was not high and the incidence of sleep disorders was 36.67%. The higher the level of occupational stress, the higher the incidence of sleep disorders. Irregular shifts can affect sleep quality and individuals with high-level professional titles experience a higher incidence of sleep disorders than those with low-level titles. The total score of the PSQI was different among the low, medium, and high stress groups. The higher the level of stress, the higher the scores of subjective sleep quality, sleep disorder, and daytime dysfunction. The scores of the PSQI, subjective sleep quality, sleep time, sleep disturbance, and daytime dysfunction in the high-stress group were higher than those in the low stress group. A case-control study found that the concentration of glucocorticoids in the sleep disorder positive group was lower than that in the sleep disorder negative group. The results of the regression analysis showed that glucocorticoid is a protective factor for sleep disorders (OR = 0.989, 95% CI: 0.983-0.995), suggesting that the higher the level of glycosaminoglycan, the less likely the subject is to have sleep disorders. For example, in the case of high occupational stress, the interaction between low and moderate occupational stress levels and glucocorticoids is a protective factor for sleep disorders.


Assuntos
Hormônios/sangue , Estresse Ocupacional/epidemiologia , Transtornos do Sono-Vigília/epidemiologia , Sono , Adulto , Estudos de Casos e Controles , China/epidemiologia , Estudos Transversais , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Estresse Ocupacional/complicações , Campos de Petróleo e Gás , Transtornos do Sono-Vigília/etiologia , Adulto Jovem
18.
Presse Med ; 48(10): 1051-1058, 2019 Oct.
Artigo em Francês | MEDLINE | ID: mdl-31473024

RESUMO

Subjects suffering from post-traumatic stress disorder present sleeping disorders like a chronic insomnia, traumatic nightmares, but also less expected, sleep breathing disorders. Sleep problems are a factor of development and maintenance of PTSD, but also a factor of resistance to treatment. After a therapy focused on PTSD, they represent frequent residual symptoms. It is necessary to couple, with the usual management of PTSD, targeted approaches for sleep problems. These targeted approaches allow an improvement of the nocturnal properties but also diurnal specific symptoms of PTSD. Stakes around primary, secondary and tertiary prevention of PTSD emerge around these sleep disorders.


Assuntos
Síndrome das Pernas Inquietas/etiologia , Síndromes da Apneia do Sono/etiologia , Transtornos do Sono-Vigília/etiologia , Transtornos de Estresse Pós-Traumáticos/complicações , Sonhos , Humanos , Síndrome das Pernas Inquietas/terapia , Prevenção Secundária , Síndromes da Apneia do Sono/terapia , Transtornos do Sono-Vigília/terapia , Transtornos de Estresse Pós-Traumáticos/prevenção & controle , Transtornos de Estresse Pós-Traumáticos/terapia , Prevenção Terciária
19.
Res Dev Disabil ; 94: 103464, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31479914

RESUMO

BACKGROUND: Many children with autism spectrum disorder (ASD) experience comorbid symptoms of attention-deficit/hyperactivity disorder (ADHD). Additionally, children with ASD and ADHD often have sleep disturbances and deficits in executive functioning (EF). In typical development, sleep disturbances are causally linked to EF deficits and exacerbate ADHD-like symptoms. AIM: The aim of this study was to determine whether caregiver-report sleep and EF difficulties predict ADHD symptoms in children with ASD. METHODS: Caregiver-report of child sleep, EF, and ADHD symptom severity was collected for 101 children with ASD, 7-11 years of age. Hierarchical linear regressions tested the independent and interactive effects of sleep and EF in predicting ADHD symptoms. RESULTS: Children with ASD were more likely to have symptoms of ADHD if they experienced both sleep and EF difficulties. Children with difficulties in working memory were particularly at risk for clinically significant symptoms of ADHD. Notably, however, sleep did not mediate or moderate the relation between working memory and ADHD symptoms in this sample, suggesting that these variables act through independent mechanisms to increase vulnerability for comorbidity. CONCLUSIONS: These results have clinical significance as sleep and EF deficits may identify an ASD subgroup that is at increased risk for a comorbid ADHD diagnosis.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade , Transtorno do Espectro Autista , Função Executiva , Transtornos da Memória , Transtornos do Sono-Vigília , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Transtorno do Deficit de Atenção com Hiperatividade/psicologia , Transtorno do Espectro Autista/epidemiologia , Transtorno do Espectro Autista/psicologia , Sintomas Comportamentais/diagnóstico , Sintomas Comportamentais/psicologia , Cuidadores , Criança , Comorbidade , Feminino , Humanos , Masculino , Transtornos da Memória/diagnóstico , Transtornos da Memória/etiologia , Transtornos da Memória/psicologia , Testes de Memória e Aprendizagem , Memória de Curto Prazo , Fatores de Risco , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/psicologia , Avaliação de Sintomas/métodos
20.
NeuroRehabilitation ; 45(2): 187-200, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31498136

RESUMO

BACKGROUND: Daylight entrains the central circadian pacemaker to the 24-hour day and is crucial for optimal alertness and sleep-quality. Rehabilitation patients tend to lack exposure to sufficient natural light. OBJECTIVE: Installed diurnal naturalistic light may reduce the known disrupted sleep quality and fatigue seen in post stroke patients. METHODS: Stroke patients were randomized to either an intervention rehabilitation unit (IU) equipped with naturalistic lighting (artificial sunlight spectrum) or to a control rehabilitation unit (CU) with standard indoor lighting. At inclusion and discharge, fatigue and subjective sleep quality were measured. RESULTS: Ninety stroke patients were included between May 2014, and June 2015. At discharge, patients from the IU experienced less fatigue than the CU patients, based on the Multidimensional Fatigue Inventory questionnaire general (IU, n = 28; CU, n = 30; diff - 20.6%, 95% confidence interval (CI) [- 35.0%; - 3.0%]; P = 0.025) and the Rested Statement (IU, n = 28; CU, n = 30; diff + 41.6%, 95% CI [+4.6%; +91.8%]; P =  0.025). No differences were detected between groups in sleepiness or subjective sleep quality by the Pittsburgh Sleep Quality Index. CONCLUSIONS: Fatigue was significantly reduced in rehabilitation patients exposed to naturalistic lighting during admission.


Assuntos
Fadiga/prevenção & controle , Fototerapia/métodos , Transtornos do Sono-Vigília/terapia , Reabilitação do Acidente Vascular Cerebral/métodos , Acidente Vascular Cerebral/complicações , Luz Solar , Atenção , Ritmo Circadiano , Fadiga/etiologia , Fadiga/terapia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sono , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/prevenção & controle , Vigília
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