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1.
Ann Ital Chir ; 92: 333-338, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34524121

RESUMO

INTRODUCTION: The Covid-19 pandemic spread rapidly throughout Turkey from March 2020 onward, and despite modified working conditions in the surgical clinics of our hospitals, some surgical patients became infected with the coronavirus during their perioperative period. AIM: The present study investigates the impact of the novel coronavirus on patients undergoing general surgical operations in our clinics during the Covid-19 pandemic. METHODS: A retrospective analysis was conducted of all surgeries performed in the general surgery clinics of two 'pandemic hospitals' between March 19 and April 30, 2020 - a period when all elective surgeries were suspended in hospitals within Turkey. Demographic data, comorbidities, choice of anesthesia method, blood parameters, duration of stay in hospital and the intensive care unit and mortality rates were compared statistically with the frequency of postoperative Covid-19 positivity in these patients. RESULTS: A total of 275 surgical operations were performed during this period. Covid-19 was identified in seven patients during the postoperative period, and was more commonly diagnosed in those who were elderly and those with comorbidities. (p=0.02, p=0.02). Statistically significant correlations were found between a Covid-19 diagnosis and admission to the intensive care unit, the length of hospital stay and the length of stay in intensive care (p<0.001, p<0.001, p=0.01). Mortality was observed in two patients who developed Covid-19 postoperatively (p= 0.03). CONCLUSIONS: The Covid-19 pandemic has had a significant impact on patients undergoing operations in our general surgery clinics. Precautionary measures taken during postoperative care should be maximized for high-risk patients. KEY WORDS: Covid-19 pandemic, General surgery clinics, Novel coronavirus, Gastrointestinal system surgery.


Assuntos
COVID-19 , Pandemias , Idoso , Teste para COVID-19 , Humanos , Estudos Retrospectivos , SARS-CoV-2 , Turquia/epidemiologia
2.
East Mediterr Health J ; 27(8): 772-781, 2021 Aug 26.
Artigo em Inglês | MEDLINE | ID: mdl-34486713

RESUMO

Background: The health and social care needs of people aged ≥ 80 years are a neglected topic. Aims: To determine the prevalence of unmet health and social care needs and associated factors in community-dwelling individuals aged ≥ 80 years in Izmir District of Balçova, Turkey. Methods: There were 1075 participants aged ≥ 80 years. The dependent variables were unmet health and social care needs. Independent variables were sociodemographic, socioeconomic and lifestyle characteristics. The data were collected in face-to-face interviews conducted at the homes and analysed by multiple logistic regression model. Ethical approval was obtained from the Non-Invasive Research Ethics Board of Dokuz Eylul University Medical Faculty (2017/26-24). Results: The mean age was 84.1 (3.7) years and 61.0% were female. Healthcare needs were expressed by 88.2% of the participants and 78.9% claimed that they had social care needs. Prevalence of unmet health and social care needs was 32.5% and 46.6%, respectively. Approximately 90.0% of their needs were covered by families. Perceived low-income status was a risk factor for unmet healthcare needs, and lack of social support was a risk factor for unmet social care needs. Additionally, not receiving formal education was a protective factor in unmet social care needs. Conclusion: Public health policy should be developed to enable better access to care, especially for the oldest people, considering that nearly one third of the participants in this study had unmet healthcare needs and almost half had unmet social care needs.


Assuntos
Acesso aos Serviços de Saúde , Apoio Social , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Necessidades e Demandas de Serviços de Saúde , Humanos , Fatores Socioeconômicos , Turquia/epidemiologia
3.
Medicine (Baltimore) ; 100(35): e27166, 2021 Sep 03.
Artigo em Inglês | MEDLINE | ID: mdl-34477174

RESUMO

ABSTRACT: In 2019, the Coronavirus disease 2019 (Covid-19) was reported in Wuhan, China. Governments in various countries had taken many safeguards. This study investigated the incidence of orthopedic trauma in a rural region epidemiologically and guided source distribution and medical professionals to sustain healthcare systems.Between December 2019 and August 2020, 1651 patients admitted to orthopedics and traumatology clinics with trauma were evaluated in this study. Patients were grouped into 3 groups: pre-covid, restriction, and permitted groups. Age, sex, and fracture types of patients were recorded.The number of patients in the pre-covid period was 629 (38.1%), those were 334 (20.2%) in the restriction period, and 688 (41.7%) patients were admitted in the permitted period. A total of 1203 (72.9%) patients with upper extremity fractures, 383 (23.2%) patients with lower extremity fractures, and 65 (3.9%) patients with axial skeleton and pelvic ring fractures were included in the study. The lowest rates were found in the restriction period when all fractures were evaluated according to the admission periods. There were significant differences between admission dates and the fractures (P < .001).In this study, a decrease in orthopedic trauma rates was observed by half in the restriction period compared with the other 2 periods. Public health precautions had led to a reduction in the incidence of orthopedic trauma in all age groups.


Assuntos
Controle de Doenças Transmissíveis , Fraturas Ósseas/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , COVID-19/epidemiologia , COVID-19/prevenção & controle , Criança , Pré-Escolar , Feminino , Humanos , Incidência , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Pandemias , Estudos Retrospectivos , SARS-CoV-2 , Turquia/epidemiologia , Adulto Jovem
5.
J World Fed Orthod ; 10(3): 127-131, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34332927

RESUMO

BACKGROUND: Coronavirus disease (COVID-19) has led to unprecedented challenges in the arts, sports, education, finance, and healthcare. The aim of this study was to compare demographic characteristics of new-patient visits for orthodontic treatment in the pandemic year (2020) versus previous years. METHODS: The retrospective study included patients who sought care at a tertiary orthodontic referral center between January 1, 2016 and December 31, 2020. Clinical and demographic characteristics, including age, age group (child, young adult, adult), gender, and numbers of monthly and annual new-patient visits were compared between the pre-pandemic (2017-2020) and post-pandemic (2020) periods. The daily average numbers of appointments were compared for 2019 versus 2020. RESULTS: The average number of monthly new-patient visits was 240.69 ± 81.48 in the pre-pandemic period, as opposed to 113.75 ± 88.89 in the year 2020 (P < 0.001). The average number of monthly new-patient visits decreased by 48.3% in 2020 compared to 2019, while the average number of daily new-patient visits in 2020 decreased significantly in all months (P < 0.05), except for January (P = 0.613) compared to the monthly numbers from the previous year. No significant difference was found between the pre-pandemic period and 2020 with regard to gender (P = 0.410). In all years, the numbers of new-patient visits were higher for women, compared with men, and for children, compared with adults. CONCLUSIONS: The results indicated a sharp decrease in the number of new-patient visits for orthodontic treatment in the pandemic year (2020) compared to previous years.


Assuntos
Agendamento de Consultas , COVID-19/epidemiologia , Acesso aos Serviços de Saúde , Ortodontia , Adolescente , Adulto , Criança , Feminino , Humanos , Masculino , Pandemias , Estudos Retrospectivos , SARS-CoV-2 , Turquia/epidemiologia
6.
PLoS One ; 16(8): e0256688, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34432854

RESUMO

This study analyzes the effects of the COVID-19 pandemic on grade inflation in higher education. Data were collected from five universities in Turkey, including grades of 152,352 students who attended 2,841 courses conducted by 903 instructors before the COVID-19 pandemic and grades of 149,936 students who attended 2,841 courses conducted by 847 instructors during the COVID-19 pandemic. The results of this study demonstrate that the COVID-19 pandemic causes a marginal increase in grades in higher education when the other factors that might explain the differences are controlled. Grade inflation of 9.21% is the highest ever reported in literature. Compared with a year ago, DD and DC grades decreased 55%; FD and FF grades decreased 31%; and the highest-grade AA increased 41% for courses taken during the pandemic. Additionally, classroom population, academic history of the instructor, class level, field, university entrance scores, and course execution and evaluation (grading) forms of course notes are important determinants. This increase can be explained by the effort of instructors who are accustomed to face-to-face settings. When they suddenly switch to distant education, they might try to grade higher to compensate for the unforeseen negative circumstances.


Assuntos
COVID-19/epidemiologia , Avaliação Educacional/estatística & dados numéricos , COVID-19/virologia , Humanos , Pandemias , SARS-CoV-2/isolamento & purificação , Estudantes , Turquia/epidemiologia , Universidades
7.
J Water Health ; 19(4): 671-681, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34371502

RESUMO

Adequate hydration is an essential component of health at every stage of life. Although many factors such as age, gender, physical activity, drug use, and illness affect hydration status, it is vital to maintain water balance, especially in infectious diseases. This study was conducted to estimate the hydration status of young adults living in Turkey during the COVID-19 pandemic. The total water intake (TWI) and total water loss of the individuals were determined using the Water Balance Questionnaire (WBQ), which consists of questions about physical activity status, frequency of food and beverage consumption, water consumption, and water loss with urine and feces. The TWI of men and women was found to be 4,776.1 and 4,777.3 mL/day, respectively (p > 0.05). It was determined that 29% of the total water was obtained from drinking water, 49% from other beverages, and 22% from food. A positive net water balance was found in all body mass index (BMI) groups, men, and women. The net water balance was statistically lower in men (2,230.6 mL) than women (2,783.8 mL) (p < 0.05). As the COVID-19 pandemic continues, studies should be done on hydration status in the more balanced populations in terms of BMI and age groups.


Assuntos
COVID-19 , Pandemias , Ingestão de Líquidos , Feminino , Humanos , Masculino , SARS-CoV-2 , Turquia/epidemiologia , Adulto Jovem
8.
East Mediterr Health J ; 27(7): 718-727, 2021 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-34369587

RESUMO

Background: Exposure to violence during childhood can have an adverse effect on health and well-being. Aims: To determine the frequency of exposure to violence among ninth-grade high school students in Kars, Turkey, and violence-related factors. Also, to examine whether frequency of exposure to violence differed with respect to school type. Methods: We included 1730 ninth-grade high school students in Kars in this cross-sectional study that used stratification and cluster sampling methods, and 2 questionnaires. The first questionnaire was used to determine the socioeconomic and sociodemographic characteristics of the students. The second questionnaire was the Exposure to Violence Scale. χ2 and backward logistic regression analyses were performed to determine the independent variables among potential risk factors and exposure to violence. Results: Exposure to violence was found to have a prevalence of 65.8% among ninth-grade high school students. Binary analysis revealed that frequency of exposure to violence was differed significantly by type of high school, place of residence, type of family, and parents' occupational status. Backward logistic regression showed that type of high school and type of family were risk factors for exposure to violence. Conclusion: The rates of exposure to violence were high among ninth-grade high school students in Kars. Preventive, protective and ameliorating intervention steps should be taken more seriously.


Assuntos
Exposição à Violência , Estudos Transversais , Humanos , Prevalência , Fatores de Risco , Instituições Acadêmicas , Estudantes , Inquéritos e Questionários , Turquia/epidemiologia , Violência
9.
Epidemiol Infect ; 149: e180, 2021 08 10.
Artigo em Inglês | MEDLINE | ID: mdl-34375576

RESUMO

Several studies have demonstrated that higher levels of vitamin D are associated with better prognosis and outcomes in infectious diseases. We aimed to compare the vitamin D levels of paediatric patients with mild/moderate coronavirus disease 2019 (COVID-19) disease and a healthy control group. We retrospectively reviewed the medical records of patients who were hospitalised at our university hospital with the diagnosis of COVID-19 during the period between 25 May 2020 and 24 December 2020. The mean age of the COVID-19 patients was 10.7 ± 5.5 years (range 1-18 years); 43 (57.3%) COVID-19 patients were male. The mean serum vitamin D level was significantly lower in the COVID-19 group than the control group (21.5 ± 10.0 vs. 28.0 ± 11.0 IU, P < 0.001). The proportion of patients with vitamin D deficiency was significantly higher in the COVID-19 group than the control group (44% vs. 17.5%, P < 0.001). Patients with low vitamin D levels were older than the patients with normal vitamin D levels (11.6 ± 4.9 vs. 6.2 ± 1.8 years, P = 0.016). There was a significant male preponderance in the normal vitamin D group compared with the low vitamin D group (91.7% vs. 50.8%, P = 0.03). C-reactive protein level was higher in the low vitamin D group, although the difference did not reach statistical significance (9.6 ± 2.2 vs. 4.5 ± 1.6 mg/l, P = 0.074). Our study provides an insight into the relationship between vitamin D deficiency and COVID-19 for future studies. Empiric intervention with vitamin D can be justified by low serum vitamin D levels.


Assuntos
COVID-19/sangue , COVID-19/complicações , Deficiência de Vitamina D/complicações , Vitamina D/sangue , Adolescente , Fatores Etários , Proteína C-Reativa/análise , Proteína C-Reativa/metabolismo , COVID-19/epidemiologia , Estudos de Casos e Controles , Criança , Pré-Escolar , Feminino , Hospitais Universitários , Humanos , Lactente , Masculino , Estudos Retrospectivos , Fatores de Risco , Fatores Sexuais , Turquia/epidemiologia , Deficiência de Vitamina D/epidemiologia
10.
Ann Clin Microbiol Antimicrob ; 20(1): 51, 2021 Aug 05.
Artigo em Inglês | MEDLINE | ID: mdl-34353332

RESUMO

PURPOSE: In this study, we aimed to evaluate the epidemiology and antimicrobial resistance (AMR) patterns of bacterial pathogens in COVID-19 patients and to compare the results with control groups from the pre-pandemic and pandemic era. METHODS: Microbiological database records of all the COVID-19 diagnosed patients in the Ege University Hospital between March 15, 2020, and June 15, 2020, evaluated retrospectively. Patients who acquired secondary bacterial infections (SBIs) and bacterial co-infections were analyzed. Etiology and AMR data of the bacterial infections were collected. Results were also compared to control groups from pre-pandemic and pandemic era data. RESULTS: In total, 4859 positive culture results from 3532 patients were analyzed. Fifty-two (3.59%) patients had 78 SBIs and 38 (2.62%) patients had 45 bacterial co-infections among 1447 COVID-19 patients. 22/85 (25.88%) patients died who had bacterial infections. The respiratory culture-positive sample rate was 39.02% among all culture-positive samples in the COVID-19 group. There was a significant decrease in extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales (8.94%) compared to samples from the pre-pandemic (20.76%) and pandemic era (20.74%) (p = 0.001 for both comparisons). Interestingly, Acinetobacter baumannii was the main pathogen in the respiratory infections of COVID-19 patients (9.76%) and the rate was significantly higher than pre-pandemic (3.49%, p < 0.002) and pandemic era control groups (3.11%, p < 0.001). CONCLUSION: Due to the low frequency of SBIs reported during the ongoing pandemic, a more careful and targeted antimicrobial prescription should be taken. While patients with COVID-19 had lower levels of ESBL-producing Enterobacterales, the frequency of multidrug-resistant (MDR) A. baumannii is higher.


Assuntos
Infecções Bacterianas/microbiologia , COVID-19/microbiologia , Coinfecção/microbiologia , Farmacorresistência Bacteriana/efeitos dos fármacos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/farmacologia , Infecções Bacterianas/tratamento farmacológico , Infecções Bacterianas/epidemiologia , COVID-19/epidemiologia , Teste de Ácido Nucleico para COVID-19 , Criança , Pré-Escolar , Coinfecção/epidemiologia , Feminino , Humanos , Lactente , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Estudos Retrospectivos , Turquia/epidemiologia , Adulto Jovem
11.
Turkiye Parazitol Derg ; 45(3): 165-170, 2021 08 04.
Artigo em Inglês | MEDLINE | ID: mdl-34346870

RESUMO

Objective: Blastocystis is a zoonotic protozoan that infects a wide range of animals, including humans and rodents. This study aimed to determine the frequency and subtype distribution of Blastocystis in laboratory rats at a laboratory animal facility in Turkey. Methods: This study included 54 male Sprague-Dawley rats from Aydin Adnan Menderes University Laboratory Animal Center. Among these rats, 30 were fed with high-fat diet (obese group) and the remaining 24 received standard chow (non-obese group). Blastocystis positivity was determined with amplification of small subunit 18S rRNA gene following their nucleic acid extraction from faecal samples. Subtypes were detected by submitting the partial 18S rRNA gene sequences to the database (pubmlst. Results: Blastocystis infection was detected in 33 (61.1%) of 54 laboratory rats. The frequency of Blastocystis was significantly different between obese and non-obese rats (p<0.05), with 43.3% and 83.3%, respectively. When referred to the database, exact matches were identified with Blastocystis subtype 4 (ST4) for all isolates. In the phylogenetic analysis of the partial 18S rDNA sequence, the sequence was closely clustered with reference ST4 subtypes from other countries, including China, Japan, United Kingdom and Czech Republic. Conclusion: This study revealed the high rate of Blastocystis colonisation in laboratory rats, posing a risk for human transmission. The comparison of obese and non-obese groups supported the idea that Blastocystis might be an indicator of healthy gut flora. The detection of ST4 in all rats agreed with previous reports of the predominance of this subtype in rodents.


Assuntos
Infecções por Blastocystis , Blastocystis , Animais , Blastocystis/genética , Infecções por Blastocystis/epidemiologia , DNA de Protozoário , Fezes , Variação Genética , Humanos , Masculino , Obesidade , Filogenia , Ratos , Ratos Sprague-Dawley , Turquia/epidemiologia
12.
Turkiye Parazitol Derg ; 45(3): 207-210, 2021 08 04.
Artigo em Inglês | MEDLINE | ID: mdl-34346877

RESUMO

Objective: This study aimed to retrospectively examine the indirect haemagglutination (IHA) test results of patients suspected of cystic echinococcosis (CE) and admitted to Bursa Uludag University Health Practice and Research Center Hospital. Methods: Serum samples in the serology laboratory of our hospital were evaluated using the commercial Cellognost® echinococcosis IHA (Siemens Healthcare Diagnostics, Marburg, Germany) test based on the manufacturer's recommendations. In the IHA test, ≥1:64 serum titres were accepted as positive. Results: Seropositivity was determined in 213 (19.9%) of 1.072 patients suspected of having CE by the IHA method. Of the patients with seropositivity, 120 (56.3%) were female and 93 (43.7%) were male. The highest positivity rate in both sexes was found in patients aged 20-29 years (22.5% in women; 14.1% in men). Conclusion: The results indicate that CE maintains its importance as a public health problem in Bursa as in Turkey.


Assuntos
Equinococose , Laboratórios , Anticorpos Anti-Helmínticos , Equinococose/diagnóstico , Equinococose/epidemiologia , Ensaio de Imunoadsorção Enzimática , Feminino , Testes de Hemaglutinação , Humanos , Masculino , Estudos Retrospectivos , Turquia/epidemiologia
13.
Work ; 69(4): 1163-1170, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34420998

RESUMO

BACKGROUND: Determining the healthcare professionals' perceptions and attitudes towards the COVID-19 pandemic will contribute to managing and struggling their efforts against COVID-19. OBJECTIVE: This study aimed to determine the perceptions and attitudes of healthcare professionals who are at the forefront in the fight against this pandemic. METHODS: In the study, the survey technique used as the data collection method and 216 participants agreed to participate. The questionnaire consisted of three sections. Reliability analysis and descriptive statistical methods used to analyze the data obtained using the SPSS package program. RESULTS: According to the study results, 80.4%of the participants perceive the probability of being infected with the COVID-19 to be very high, and 64%of them consider that the conditions are very favorable for them to be infected. More than half of them are afraid of being infected and believe that if they contract COVID-19, adverse effects may continue for a long time. Furthermore, almost all participants (96.20%) consider personal protective equipment beneficial and will protect them from the COVID-19 as a wise preventive measure. However, 82.30%of the participants stated that using personal protective equipment is uncomfortable, and 76.60%said it is challenging to take care of patients while using personal protective equipment. CONCLUSIONS: The current study results show that healthcare professionals are aware of how serious COVID-19 is, understand the importance of protective equipment in protection from COVID-19, and are seriously afraid of COVID-19. Given that the fears of healthcare professionals may have adverse effects on them, it is recommended that healthcare administrators take measures to comfort healthcare workers and ensure that they maintain their positive attitude towards COVID-19.


Assuntos
COVID-19 , Pandemias , Conhecimentos, Atitudes e Prática em Saúde , Pessoal de Saúde , Humanos , Percepção , Reprodutibilidade dos Testes , SARS-CoV-2 , Turquia/epidemiologia
14.
Arch Virol ; 166(9): 2461-2468, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34212242

RESUMO

Bovine coronavirus (BCoV) can be spread by animal activity. Although cattle farming is widespread in Turkey, there are few studies of BCoV. The aim of this study was to evaluate the current situation regarding BCoV in Turkey. This is the first study reporting the full-length nucleotide sequences of BCoV spike (S) genes in Turkey. Samples were collected from 119 cattle with clinical signs of respiratory (n = 78) or digestive tract (n = 41) infection on different farms located across widely separated provinces in Turkey. The samples were screened for BCoV using RT-nested PCR targeting the N gene, which identified BCoV in 35 samples (9 faeces and 26 nasal discharge). RT-PCR analysis of the S gene produced partial/full-length S gene sequences from 11 samples (8 faeces and 3 nasal discharge samples). A phylogenetic tree of the S gene sequences was made to analyze the genetic relationships among BCoVs from Turkey and other countries. The results showed that the local strains present in faeces and nasal discharge samples had many different amino acid changes. Some of these changes were shown in previous studies to be critical for tropism. This study provides new data on BCoV in Turkey that will be valuable in designing effective vaccine approaches and control strategies.


Assuntos
Doenças dos Bovinos/epidemiologia , Infecções por Coronavirus/veterinária , Coronavirus Bovino/genética , Diarreia/veterinária , RNA Viral/genética , Infecções Respiratórias/veterinária , Glicoproteína da Espícula de Coronavírus/genética , Agricultura , Substituição de Aminoácidos , Animais , Bovinos , Doenças dos Bovinos/virologia , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/virologia , Coronavirus Bovino/classificação , Diarreia/epidemiologia , Diarreia/virologia , Monitoramento Epidemiológico/veterinária , Evolução Molecular , Fezes/virologia , Humanos , Mutação , Cavidade Nasal/virologia , Filogenia , Infecções Respiratórias/epidemiologia , Infecções Respiratórias/virologia , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Análise de Sequência de DNA , Turquia/epidemiologia
15.
J Coll Physicians Surg Pak ; 31(7): S93-S98, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-34271803

RESUMO

OBJECTIVE: To investigate the symptoms and laboratory results of children hospitalised with the diagnosis of COVID-19, aiming to reveal the characteristics of symptomatic cases. STUDY DESIGN: A descriptive cross-sectional study. PLACE AND DURATION OF STUDY: Department of Pediatrics, Kastamonu Training and Research Hospital, Kastamonu, Turkey from March to December 2020. METHODOLOGY: Seventy-nine children, hospitalised with the diagnosis of COVID-19, were included in the study and were divided into two groups as symptomatic and asymptomatic. The demographic data, laboratory results and clinics of the patients of the two groups were compared. RESULTS: The mean age of participants was 10.43 ± 5.91 (0-17) years, and 57% (n=45) of them were girls. Five patients in the symptomatic group had comorbidities (2 allergic asthma,  cerebral palsy, type-1 diabetes mellitus and anorexia nervosa). The most common symptom was fever (36.7%, n=29). It was noteworthy that everyone with an NLR >3.13 (high-NLR) was symptomatic. Significantly more patients in the high-NLR group were symptomatic compared with the low-NLR group (p=0.005). On the other hand, symptomatic children had significantly higher levels of C-reactive protein (2.8 (IQR: 1.2-10.0) mg/L vs. 1.4 (IQR: 0.4-2.0) mg/L, p=0.011); and procalcitonin (0.05 (IQR: 0.02-0.10) ng/mL vs. 0.01 (IQR: 0.00-0.03) ng/mL, p<0.001) than those without symptoms. One of the children with cerebral palsy died from pneumonia during the study. CONCLUSION: C-reactive protein, procalcitonin and NLR levels were found to be significantly higher in symptomatic children. NLR can be suggested as a potential marker associated with disease severity in COVID-19 patients, which needs to be supported by other studies. Key Words: COVID-19, Children, Neutrophil / lymphocyte ratio, C-reactive protein, Procalcitonin.


Assuntos
COVID-19 , Pediatria , Adolescente , COVID-19/sangue , Criança , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Linfócitos/metabolismo , Masculino , Neutrófilos/metabolismo , Estudos Retrospectivos , SARS-CoV-2 , Turquia/epidemiologia
16.
J Coll Physicians Surg Pak ; 31(7): S99-S103, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-34271804

RESUMO

OBJECTIVE: To analyse whether prealbumin could be a new biomarker for predicting mortality in severe COVID-19 patients. STUDY DESIGN: An observation study. PLACE AND DURATION OF STUDY: Intensive care units (ICU) of Sakarya University Training and Research Hospital, Sakarya, Turkey, from October 2020 to December 2020. METHODOLOGY: The data of 149 patients, who were admitted to the ICU were collected and analysed retrospectively. Routine blood samples were collected from all patients at the time of admission to the ICU; and 102 patients with the mortal course and 47 patients with the non-mortal course were included in the study. The data obtained from these patients were analyzed in the biostatistics programme.  Results: The median age of all patients was 68 years; while 94 of them were males (63.1%) and 55 of them were females (36.9%). Median levels of potassium (K) (p=0.04), uric acid (p=0.001), C-reactive protein (CRP) (p=0.004), and procalcitonin (PCT) (p<0.001) were significantly higher and median level of prealbumin (p=0.002) was significantly lower in the deceased group. The cut-off level of prealbumin for mortality was found as 0.085 g/L (p=0.002). Further analysis revealed that the risk of mortality was found as 2.193 times more in patients with prealbumin levels of <0.085 g/L (Odds Ratio (OR): 2.193, 95% CI: 1.084-4.434). CONCLUSION: As a result of this study, it was found that patients with lower levels of prealbumin at the time of admission to the ICU have a higher risk for mortality. It was showed that prealbumin can be a useful biomarker for predicting mortality in patients with severe COVID-19. Key Words: Prealbumin, COVID-19, Mortality, Prognostic biomarkers, Severe disease.


Assuntos
COVID-19 , Pré-Albumina , Idoso , Biomarcadores , Proteína C-Reativa/análise , Feminino , Humanos , Unidades de Terapia Intensiva , Masculino , Pré-Albumina/análise , Prognóstico , Estudos Retrospectivos , SARS-CoV-2 , Turquia/epidemiologia
17.
Comp Immunol Microbiol Infect Dis ; 78: 101688, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34229197

RESUMO

This study aimed to investigate the Feline immunodeficiency virus (FIV) / Feline leukemia virus (FeLV) infection prevalence among looking healthy stray cats in Western Turkey by serologic and molecular-based tests. A total of 1008 blood samples from the stray cats were used in this study. All samples were tested for FIV antibodies / proviral DNA and FeLV antibodies / antigens / proviral DNA. The genetic characterization and phylogenetic analysis of FeLV and FIV were carried out in this study. These cats also tested for Leishmaniasis and Toxoplasmosis previously. FIV Ab and proviral DNA detected in 25.2 % and 25.5 % of samples, respectively. FeLV Ab, Ag, proviral DNA positivity was in 45.2 %, in 3.3 %, in 69.7 %, respectively. The molecular detection and phylogenetic analysis of the current FeLV pol gene and FIV gag gene performed. The molecular characterization for the pol gene of FeLV (enFeLV and exFeLV) among Turkey's cat population was reported for the first time. The exFeLV pol sequences closer to the FeLV-A genotype, and the enFeLV pol sequences overlapped with other enFeLV. The current FIV gag sequences were clustered within the subtypes A, B, and C. The findings revealed FeLV subtype A and FIV subtype-A, subtype-B, subtype-C circulate among Turkish stray cats. Single and multiple co-infection positivity was found higher compared to previous reports.


Assuntos
Doenças do Gato , Síndrome de Imunodeficiência Adquirida Felina , Vírus da Imunodeficiência Felina , Leucemia Felina , Animais , Doenças do Gato/epidemiologia , Gatos , Síndrome de Imunodeficiência Adquirida Felina/epidemiologia , Vírus da Imunodeficiência Felina/genética , Vírus da Leucemia Felina/genética , Leucemia Felina/epidemiologia , Filogenia , Turquia/epidemiologia
18.
Epidemiol Infect ; 149: e191, 2021 07 02.
Artigo em Inglês | MEDLINE | ID: mdl-34210379

RESUMO

The prevalence of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is increasing day by day in the region, including Turkey. The study aimed to examine AIDS-related deaths in Turkey between 2009 and 2018 according to the national death registration system records. In this descriptive study, data on AIDS-related deaths were obtained from the Turkish Statistical Institute. The data consist of the cause of death codes, year of death, age and gender. Findings were presented using numbers and percentages. Seven hundred twenty-one AIDS-related deaths were reported in Turkey between 2009 and 2018. AIDS-related deaths in Turkey increased more than twice at the end of 10 years. The male/female death ratio is 4.5. Deaths under the age of 15 were 4.2% in total; however, they were increased to 10.2% in 2018. AIDS-related deaths are decreasing in the world but increasing in Turkey. The data from the Ministry of Health do not match the data of the national death registration system. Establishing a strong and accurate HIV/AIDS reporting system and identifying the causes and risk groups of this increase in AIDS-related deaths are critical.


Assuntos
Síndrome de Imunodeficiência Adquirida/mortalidade , Infecções por HIV/mortalidade , Síndrome de Imunodeficiência Adquirida/epidemiologia , Adulto , Fatores Etários , Feminino , Infecções por HIV/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Fatores Sexuais , Turquia/epidemiologia
19.
Future Oncol ; 17(25): 3373-3381, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34291649

RESUMO

Aim: To assess the anxiety levels of breast cancer patients during the COVID-19 pandemic. Materials & methods: A total of 298 patients completed the State-Trait Anxiety Inventory (STAI-S and STAI-T) and the Visual Analogue Scale for Anxiety (VAS) and VAS for Anxiety in COVID-19 (VAS-CoV). Results: 144 patients were in the high anxiety category for STAI-S, and 202 patients were in the high anxiety category for STAI-T. STAI-T score was significantly high in the metastatic group (p = 0.017). VAS-CoV score in the hormonotherapy group was significantly higher than in the no-treatment group (p = 0.023). There was a positive correlation between VAS-CoV and VAS levels (r = 0.708, p < 0.001), VAS-CoV and STAI-S and STAI-T scores (r = 0.402, p < 0.001; r = 0.185, p = 0.001, respectively), and a negative correlation between education years and STAI-T scores (r = -0.172, p = 0.003). Conclusion: The COVID-19 pandemic is related to high anxiety levels in breast cancer patients.


Assuntos
Ansiedade/epidemiologia , Neoplasias da Mama/epidemiologia , Neoplasias da Mama/psicologia , COVID-19/epidemiologia , Idoso , Idoso de 80 Anos ou mais , Ansiedade/diagnóstico , Ansiedade/terapia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/terapia , COVID-19/virologia , Comorbidade , Estudos Transversais , Gerenciamento Clínico , Feminino , Humanos , Pessoa de Meia-Idade , Vigilância em Saúde Pública , SARS-CoV-2 , Fatores Socioeconômicos , Turquia/epidemiologia
20.
Niger J Clin Pract ; 24(7): 997-1004, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34290175

RESUMO

Background: Methicillin-resistant Staphylococcus aureus (MRSA) has been a widespread problem in Turkish hospitals. Aims: The aim of this study was to investigate the staphylococcal toxin genes of the clinical and nasal MRSA isolates, and their antibiotic resistance profiles. Materials and Methods: Isolation of nasal and clinical bacteria was done following standard microbiological methods. The presence of antimicrobial resistance genes (mec A, pvl, tsst-1, and SEs genes) was determined using the real-time polymerase chain reaction (PCR) assay. Results: Among nasal MRSA isolates, 66.7% were toxigenic. The distribution of genes was as follows: pvl 26.7%, tsst-1 3.3%, and SEs 36.7%. Therefore, the nasal MRSA isolates had a rate of 23.3% multidrug resistance (MDR) pattern to the non-beta-lactams antibiotics. All (100%) clinical MRSA isolates were found to be toxigenic. The distribution of genes was as follows; pvl 10%, tsst-1 6.7%, and SEs 100%. The clinical MRSA isolates had a rate of 60% MDR. Conclusions: Following detection of pvl, tsst-1, and SEs among nasal and clinical MRSA isolates, and the presence of high antimicrobial resistance, the spread of these strains may be an additional factor contributing to the emergence of community-acquired (CA)-MRSA and hospital-acquired (HA)-MRSA. This study is the first to determine the resistance to linezolid and tigecycline in both nasal and clinical MRSA isolates, for the first time in Turkey. All nasal and clinical MRSA isolates were uniformly susceptible to vancomycin and quinupristin-dalfopristin. Our findings show that MRSA infections in Turkey can be empirically treated with vancomycin and quinupristin-dalfopristin based on the lack of demonstrable resistance to these drugs.


Assuntos
Staphylococcus aureus Resistente à Meticilina , Infecções Estafilocócicas , Antibacterianos/farmacologia , Exotoxinas/genética , Humanos , Staphylococcus aureus Resistente à Meticilina/genética , Testes de Sensibilidade Microbiana , Infecções Estafilocócicas/tratamento farmacológico , Infecções Estafilocócicas/epidemiologia , Turquia/epidemiologia
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