Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 10.061
Filtrar
1.
Medicine (Baltimore) ; 98(39): e17297, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31574853

RESUMO

As a modifiable risk factor for cardiovascular disease, presence of hypertension (HT) necessitates the awareness of asymptomatic organ damage (AOD). The aim of this study was to measure plasma micro RNA-21 (miR-21) and the parameters that reflect AOD such as carotid intima-media thickness (CIMT), microalbuminuria (MAU) in hypertensive patients compared with healthy controls. In addition, the aim of this study was to evaluate plasma miR-21 levels in HT patients with AOD.This study was designed as a cross-sectional observational study. The study includes 2 groups: 32 patients with HT and 32 healthy controls. First, we compared these 2 groups. Then, to underline the relationship between plasma miR-21 and HT, hypertensive patients were divided into 2 groups: with AOD and without AOD.Sixteen patients with HT had AOD. MiR-21 levels significantly correlated with clinical systolic and diastolic blood pressure, MAU, C-reactive protein, and CIMT. CIMT, miR-21, and MAU levels were significantly higher in patients with AOD.Our study showed increased miR-21 levels in HT patients with AOD.


Assuntos
Albuminúria , Doenças Cardiovasculares , Hipertensão , MicroRNAs/sangue , Adulto , Albuminúria/diagnóstico , Albuminúria/etiologia , Doenças Assintomáticas/epidemiologia , Pressão Sanguínea/fisiologia , Proteína C-Reativa/análise , Doenças Cardiovasculares/diagnóstico , Doenças Cardiovasculares/epidemiologia , Doenças Cardiovasculares/etiologia , Espessura Intima-Media Carotídea , MicroRNA Circulante/análise , Correlação de Dados , Estudos Transversais , Feminino , Humanos , Hipertensão/complicações , Hipertensão/diagnóstico , Hipertensão/genética , Hipertensão/fisiopatologia , Masculino , Pessoa de Meia-Idade , Turquia/epidemiologia
2.
Niger J Clin Pract ; 22(8): 1055-1062, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31417047

RESUMO

Background: Turkey is the third most populous country of the European region located at the crossroads of Asia, Europe, and the Middle East. In Turkey, approximately 2 million pregnancies occur every year. Half of the pregnancies are involuntary, and five out of every 100 pregnancies end with wanted abortion. There are limitations in access to modern methods in the north of Turkey. This study was aimed to determine the factors associated with better attitudes and participation to family planning (FP) services in primary care settings from Northern Turkey. Materials and Methods: This cross-sectional study, based on primary care settings, was conducted in the Middle Black Sea Region of Turkey with 400 married men. Male attitudes and participation were measured by a questionnaire form. Chi-square testing and logistic regression analyses were applied. Results: We found that male participation was present in 302 participants (75.5%), and 363 participants (90.8%) approved the use of FP. Male participation was significantly different by age, occupation, education, marriage age, spouses' education and occupation, and attitudes towards FP. Based on multivariate analysis, male participation was significantly associated with spouses' level of education, employment status, currently using FP, and the perception of spousal communication. Conclusion: Better participation existed among participants with higher educated spouses, employed spouses, current users of FP, and the better self-perception of communication.


Assuntos
Comportamento Contraceptivo , Anticoncepção/estatística & dados numéricos , Serviços de Planejamento Familiar/estatística & dados numéricos , Conhecimentos, Atitudes e Prática em Saúde , Cônjuges/psicologia , Adolescente , Adulto , Anticoncepção/psicologia , Estudos Transversais , Serviços de Planejamento Familiar/métodos , Feminino , Humanos , Masculino , Casamento , Pessoa de Meia-Idade , Gravidez , Atenção Primária à Saúde , Fatores Socioeconômicos , Cônjuges/estatística & dados numéricos , Inquéritos e Questionários , Turquia/epidemiologia
3.
Niger J Clin Pract ; 22(8): 1063-1069, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31417048

RESUMO

Aim: The objective of this study was to determine the prevalence of burnout syndrome and associated factors among family physicians before and after family medicine system (FMS). Materials and Method: The first part of the study was conducted in 2008 (pre-FMS) and the second part in 2012 (post-FMS). Physician's burnout was investigated by using the Maslach Burnout Inventory (MBI). In total, 139 physicians had been participating pre-FMS and 246 physician's post-FMS. Results: The mean pre-FMS emotional exhaustion score was 15.7 ± 5.8, increasing significantly to 17.14 ± 7.5 post-FMS (P = 0.045). Mean pre-FMS and post-FMS depersonalization and reduced personal accomplishment scores were similar (P > 0.05). Age was negatively correlated with depersonalization in this study (P = 0.012) and positively correlated with personal accomplishment (P = 0.001). The primary care physicians in the post-FMS period were older, female physicians had a greater preference for primary care, and the levels of married doctors were higher. In addition, a higher level of physicians also owned their own home and cars compared to the pre-FMS period. A negative correlation has been reported between physicians' burnout levels and home or car ownership in the present study. Conclusion: Our findings suggest that physicians working under the family medicine system, a new primary care model, are at greater risk of emotional exhaustion, but that no change has occurred in terms of personal accomplishment or depersonalization, despite this new system.


Assuntos
Esgotamento Profissional/psicologia , Estresse Ocupacional/psicologia , Médicos de Família/psicologia , Carga de Trabalho , Adulto , Esgotamento Profissional/epidemiologia , Estudos Transversais , Despersonalização , Emoções , Medicina de Família e Comunidade/organização & administração , Feminino , Humanos , Satisfação no Emprego , Masculino , Pessoa de Meia-Idade , Estresse Ocupacional/epidemiologia , Prevalência , Atenção Primária à Saúde/organização & administração , Inquéritos e Questionários , Turquia/epidemiologia
4.
Niger J Clin Pract ; 22(8): 1070-1077, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31417049

RESUMO

Background: The World Health Organization defines obesity as an abnormal or excessive fat accumulation that can damage health. Aims: This study aims to evaluate the prevalence of obesity and risk factors in high school students in Erzurum City Center. Study Design and Methods: A cross-sectional study was conducted. The number of students participating in the study was 845, including 47.6% females and 52.4% males. Data collection was done by surveys filled in under supervision. Anthropometric measurements were performed by the researchers. Predictions of the Extended International Obesity Task Force were used for body mass index. Parents' body mass indexes were calculated by self-report and classified according to cut-off points for adults in the world health community. A systematic review of the local literature published between 2004 and 2013 was drafted. Results: In girls and boys, the frequency of overweight was 26.9% and 25.7%, respectively, while the frequency of obesity was 12.4% and 9.5%. A logistic regression analysis was performed to reveal significant risk factors for overweight/obesity. Weekly exercise status [odds ratio = 3.0, 95% confidence interval CI (1.2-7.8)] and school transfer % CI = (1.1-7.2) were important independent risk factors for obesity. The local literature showed a 4.3-fold increase in the prevalence of obesity within 10 years. Conclusion: The prevalence of obesity and overweight in adolescents requires the implementation of effective programs to fight this epidemic. Health education targeting peers and their parents, peer education, screening of risk groups, and controlling the sale of unhealthy foods can be some interventions.


Assuntos
Obesidade/epidemiologia , Sobrepeso/epidemiologia , Estudantes/estatística & dados numéricos , Adolescente , Índice de Massa Corporal , Criança , Estudos Transversais , Exercício , Feminino , Humanos , Estilo de Vida , Masculino , Prevalência , Fatores de Risco , Instituições Acadêmicas , Fatores Socioeconômicos , Inquéritos e Questionários , Turquia/epidemiologia
5.
Niger J Clin Pract ; 22(8): 1099-1108, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31417053

RESUMO

Background: Upper gastrointestinal system (GIS) bleeding is one of the most common causes of mortality and morbidity. The predictive values of pre-endoscopic Rockall score (PERS), full Rockall score (FRS), Glasgow-Blatchford score (GBS), pre-endoscopic Baylor score (PEBS), and full Baylor score (FBS) to predict bleeding at follow-up, endoscopic therapy, blood transfusion requirement, and death are investigated in our study. Methods: This study was retrospectively conducted in patients admitted to emergency department with upper GIS bleeding. Demographic and clinical characteristics of the patients were recorded. The relationships of the aforementioned scores with in-hospital termination, bleeding at follow-up, endoscopic therapy, blood transfusion requirement, and death were explored. Results: The study included a total of 420 subjects, of which 269 (64%) were men. All scoring systems were able to predict transfusion need and GBS was superior to other scores (P < 0.0001). In terms of endoscopic treatment, it was determined that only PERS, FRS, and FBS were statistically significant in predicting ability and PERS >3, FRS >5 and FBS >10 patients needed endoscopic treatment. All scoring systems were able to predict rebleeding. In comparison of two groups for rebleeding, it was found that PEBS was better able to predict bleeding during follow-up than both FRS and FBS, and PERS was better able to predict bleeding during follow-up than both FRS and FBS. All scoring systems were able to predict mortality. FRS and PERS scores had a greater discriminatory power for predicting death than the rest of the scores (P < 0.001). Conclusion: All scoring systems were effective for predicting need for blood transfusion, rebleeding, and death. GBS had more predictive power for transfusion need, PERS and PEBS for rebleeding, and FRS for mortality. PERS, FRS, and FBS were found to be effective in predicting endoscopic treatment.


Assuntos
Hemorragia Gastrointestinal/diagnóstico , Hospitalização/estatística & dados numéricos , Medição de Risco/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Transfusão de Sangue/estatística & dados numéricos , Serviço Hospitalar de Emergência , Endoscopia do Sistema Digestório , Feminino , Hemorragia Gastrointestinal/etiologia , Hemorragia Gastrointestinal/mortalidade , Hemorragia Gastrointestinal/terapia , Mortalidade Hospitalar , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Prognóstico , Curva ROC , Estudos Retrospectivos , Índice de Gravidade de Doença , Turquia/epidemiologia
6.
Work ; 63(3): 457-467, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31322585

RESUMO

BACKGROUND: Given that shift work spreads across many different business sectors, studies of its adverse effects are very topical. Much research has been done on the negative impact of shift work, but many researchers have not focused on its impact in a multicultural environment. OBJECTIVE: The aim of this study was to map out how shift work is perceived by workers in two different shift regimes and two national groups. METHODS: The research was carried out on Czech manufacturing workers and Turkish airport ground personnel using a questionnaire. The impact of shift work was studied from physical, mental, social and health aspects with connection to family status and gender. For statistical evaluation, Pearson's chi-squared test of independence was used. The effect of shift work on workers' performance and scrap rate was analysed only on the sample of the manufacturing workers. RESULTS: Fifty-five Czech male workers, 49 Turkish male workers and 60 Turkish female workers participated in the survey. The dependence between sexes was confirmed for mental aspects and sleeping routines. The main difference between nationalities is in work attitude, social aspects and sleeping routines. According to the family status, the difference was confirmed in all areas except social aspects. The lowest values of productivity and the highest scrap rate were observed on night shifts and the maximum productivity and lowest scrap rates were observed on afternoon shifts. CONCLUSIONS: Some of the basic assumptions were confirmed which suggests that a multicultural environment has an influence on the perception of shift work by the nations and gende.


Assuntos
Diversidade Cultural , Jornada de Trabalho em Turnos/efeitos adversos , Adolescente , Adulto , República Tcheca/epidemiologia , República Tcheca/etnologia , Humanos , Masculino , Indústria Manufatureira/métodos , Indústria Manufatureira/normas , Pessoa de Meia-Idade , Jornada de Trabalho em Turnos/psicologia , Transtornos do Sono do Ritmo Circadiano/epidemiologia , Transtornos do Sono do Ritmo Circadiano/etnologia , Transtornos do Sono do Ritmo Circadiano/etiologia , Inquéritos e Questionários , Turquia/epidemiologia , Turquia/etnologia , Tolerância ao Trabalho Programado/psicologia , Local de Trabalho/psicologia , Local de Trabalho/normas
7.
Pol J Microbiol ; 68(2): 165-171, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31257789

RESUMO

Hand, foot, and mouth disease (HFMD) is caused by various serotypes of Enterovirus genus. Coxsackievirus A16 (CV-A16) and enterovirus A71 (EV-A71) were known to be the only responsible agents for these epidemics; however, this opinion was challenged after the detection that coxsackievirus A6 (CV-A6) was the responsible species for the outbreak in Finland in 2008. HFMD is frequently seen in Turkey, and no detailed study on its clinical and microbiological epidemiology has previously been reported. The present study addresses this question. Twenty-seven patient samples collected between 2015 and 2017 were included in the study. Typing was conducted by RT-PCR and the sequencing applied directly to patient's samples and as well as to the viral cultures with pan-enterovirus and serotype-specific primers. The presence of Enterovirus in 12 of 27 HFMD samples was shown with RT-PCR. The causative agent for three of these 12 samples was CV-A16, one of the most frequent two serotypes around the world, and the remaining nine samples was CV-A6. The findings of the study are relevant since it pertains to the molecular epidemiology of HFMD in Turkey, a gateway country where different serotypes might be circulating and transmitted. The findings also support the notion that CV-A6 cases are rising in number, which has caused more severe clinical features and widespread rashes in recent outbreaks.Hand, foot, and mouth disease (HFMD) is caused by various serotypes of Enterovirus genus. Coxsackievirus A16 (CV-A16) and enterovirus A71 (EV-A71) were known to be the only responsible agents for these epidemics; however, this opinion was challenged after the detection that coxsackievirus A6 (CV-A6) was the responsible species for the outbreak in Finland in 2008. HFMD is frequently seen in Turkey, and no detailed study on its clinical and microbiological epidemiology has previously been reported. The present study addresses this question. Twenty-seven patient samples collected between 2015 and 2017 were included in the study. Typing was conducted by RT-PCR and the sequencing applied directly to patient's samples and as well as to the viral cultures with pan-enterovirus and serotype-specific primers. The presence of Enterovirus in 12 of 27 HFMD samples was shown with RT-PCR. The causative agent for three of these 12 samples was CV-A16, one of the most frequent two serotypes around the world, and the remaining nine samples was CV-A6. The findings of the study are relevant since it pertains to the molecular epidemiology of HFMD in Turkey, a gateway country where different serotypes might be circulating and transmitted. The findings also support the notion that CV-A6 cases are rising in number, which has caused more severe clinical features and widespread rashes in recent outbreaks.


Assuntos
Enterovirus Humano B/isolamento & purificação , Doença de Mão, Pé e Boca/epidemiologia , Doença de Mão, Pé e Boca/virologia , Epidemiologia Molecular/métodos , Animais , Linhagem Celular , Cercopithecus aethiops , Criança , Pré-Escolar , Enterovirus Humano B/classificação , Enterovirus Humano B/genética , Feminino , Humanos , Lactente , Masculino , Tipagem Molecular , Turquia/epidemiologia , Células Vero
8.
Niger J Clin Pract ; 22(7): 936-942, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31293258

RESUMO

Aim: The high incidence of caries in first permanent molars (FPMs) makes premature extraction of these teeth common. The extraction of the permanent teeth results in various changes in the dental arch. The aim of this study was to evaluate space closure, the eruption of second permanent molars (SPMs), and changes in dental arch after extraction of the FPMs. Materials and Methods: Eruption of 83 SPMs was recorded and radiographically developmental stage of these SPMs in the pre-extraction panoramic radiograph was assessed. Space was measured between the distal surface of the second premolar and the mesial surface of SPM. Results: Out of 55 patients, 28 (50.9%) were males and 27 (49.1%) were females. Thirty-seven (44.6%) of 83 teeth belonged to category 1, 17 (20.5%) teeth belonged to category 2, and 5 (6.02%) teeth belonged to category 3. Although category 4 was not found, 24 (28.9%) teeth were observed to be in category 5. Out of all SPMs, 10.8% represented the ''ideal'' stage of Demirjian's dental development, stage E. Conclusion: In patients who had the FPMs extracted before the eruption of the SPM, it is important with regards to the patients' comfort and health to review the patient regularly and to determine any need for orthodontic treatment.


Assuntos
Mineração de Dados , Arco Dental , Cárie Dentária/cirurgia , Dente Molar/cirurgia , Erupção Dentária/fisiologia , Extração Dentária/métodos , Adolescente , Dente Pré-Molar , Criança , Cárie Dentária/epidemiologia , Dentição Permanente , Feminino , Humanos , Incidência , Masculino , Radiografia Panorâmica , Turquia/epidemiologia
9.
Pan Afr Med J ; 32: 181, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31312295

RESUMO

Introduction: The term anti-nuclear antibody (ANA) is used to define a large group of autoantibodies which specifically bind to nuclear elements. Although healthy individuals may also have ANA positivity, the measurement of ANA is generally used in the diagnosis of autoimmune disorders. However, various studies have shown that ANA testing may be overused, especially in pediatrics clinics. Our aim was to investigate the reasons for antinuclear antibody (ANA) testing in the general pediatrics and pediatric rheumatology clinics of our hospital and to determine whether ANA testing was ordered appropriately by evaluating chief complaints and the ultimate diagnoses of these cases. Methods: The medical records of pediatric patients in whom ANA testing was performed between January 2014 and June 2016 were retrospectively evaluated. Subjects were grouped according to the indication for ANA testing and ANA titers. Results: ANA tests were ordered in a total of 409 patients during the study period, with 113 positive ANA results. The ANA test was ordered mostly due to joint pain (50% of the study population). There was an increased likelihood of autoimmune rheumatic diseases (ARDs) with higher ANA titer. The positive predictive value of an ANA test was 16% for any connective tissue disease and 13% for lupus in the pediatric setting. Conclusion: in the current study, more than one-fourth of the subjects were found to have ANA positivity, while only 15% were ultimately diagnosed with ARDs. Our findings underline the importance of an increased awareness of correct indications for ANA testing.


Assuntos
Anticorpos Antinucleares/sangue , Doenças Autoimunes/diagnóstico , Doenças do Tecido Conjuntivo/diagnóstico , Doenças Reumáticas/diagnóstico , Adolescente , Instituições de Assistência Ambulatorial , Doenças Autoimunes/epidemiologia , Doenças Autoimunes/imunologia , Criança , Pré-Escolar , Doenças do Tecido Conjuntivo/epidemiologia , Doenças do Tecido Conjuntivo/imunologia , Feminino , Humanos , Lúpus Eritematoso Sistêmico/diagnóstico , Lúpus Eritematoso Sistêmico/epidemiologia , Lúpus Eritematoso Sistêmico/imunologia , Masculino , Valor Preditivo dos Testes , Estudos Retrospectivos , Doenças Reumáticas/epidemiologia , Doenças Reumáticas/imunologia , Turquia/epidemiologia
10.
Turk J Ophthalmol ; 49(3): 142-148, 2019 06 27.
Artigo em Inglês | MEDLINE | ID: mdl-31245976

RESUMO

Objectives: The aim of this study was to evaluate the prevalence of dry eye symptoms among lecturers. Materials and Methods: The study included 254 lecturers employed at Mersin University. The lecturers were selected by simple random sampling from lists obtained from the personnel department. Data were obtained between November 15 and December 15, 2017 using a questionnaire developed by the researchers and the Ocular Surface Disease Index (OSDI). The data were evaluated using descriptive statistics, Student's t-test, ANOVA, and correlation tests with the SPSS package program. Results: Of the lecturers who participated in the study, 52.8% were male and 47.2% were female, and the mean age was 39.29±9.41 years. According to OSDI scores, 20.5% of the participants had mild, 15% had moderate, and 36.5% had severe disease. There were significant differences in mean OSDI score based on sex (p<0.001), alcohol use (p=0.01), continuous drug use (p=0.03), wearing glasses (p=0.04), history of dry eye (p<0.001), and presence of dry eye symptoms (p<0.001). There were also significant differences between the OSDI score categories in terms of sex (p<0.001), smoking status (p=0.04), wearing glasses (p=0.03), history of dry eye (p<0.001), and presence of dry eye symptoms. The only factor significantly correlated with OSDI score was daily duration of computer usage (p=0.009). Conclusion: Our study showed that a substantial proportion of lecturers experience dry eye symptoms, and OSDI scores were associated with daily duration of computer use. Determining the factors associated with dry eye is important for the planning of preventive interventions.


Assuntos
Síndromes do Olho Seco/epidemiologia , Doenças Profissionais/epidemiologia , Exposição Ocupacional/efeitos adversos , Qualidade de Vida , Ensino , Lágrimas/metabolismo , Adulto , Idoso , Estudos Transversais , Síndromes do Olho Seco/diagnóstico , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/diagnóstico , Prevalência , Estudos Retrospectivos , Perfil de Impacto da Doença , Inquéritos e Questionários , Turquia/epidemiologia , Adulto Jovem
11.
Turk J Ophthalmol ; 49(3): 149-153, 2019 06 27.
Artigo em Inglês | MEDLINE | ID: mdl-31245977

RESUMO

Objectives: To determine length of hydroxychloroquine use and cumulative dose and evaluate the ocular effects by 10-2 central visual field test, microperimetry (MP), color fundus photography, optical coherence tomography (OCT), and fundus autofluorescence (FAF) in hydroxychloroquine users. Materials and Methods: Patients who used hydroxychloroquine continuously for at least 2 years for various connective tissue diseases were included in the study. A total of 300 eyes of 150 patients aged 19-78 years who were followed due to risk of developing hydroxychloroquine maculopathy in the Istanbul University Istanbul Faculty of Medicine Ophthalmology Department between the years 1995-2017 were evaluated. Best corrected visual acuity (BCVA), biomicroscopic, and fundoscopic examination were performed at all visits. MP, FAF, OCT, fundus photography, and central 10-2 visual field examinations were performed 3 times at 6-month intervals. Results: The mean age of patients was 48.9±10.8 years; 141 (94%) patients were female and 9 (6%) were male. The mean duration of hydroxychloroquine use was 10.5±6.4 (2-30) years. Fifty-six patients had been using the drug for 5 years or less. The mean cumulative drug dose was 754.7±447.2 (146-1825) g. Mean BCVA was 0.02±0.08 LogMAR at all follow-up visits (p=0.999). Mean MP values at the first, second, and third examinations were 14.07±3.24 dB, 14.18±3.35 dB, and 14.54±2.79 dB, respectively (p>0.05). Mean central macular thickness was 221.9±19.8 µm at initial examination, 221.8±19.9 µm at the second visit, and 221.8±19.8 µm at the final visit (p=0.113). There was a weak negative correlation between age and MP values at all three visits (visit 1: p=0.003, r=- 0.170; visit 2: p=0.001, r=-0.185, visit 3: p=0.011, r=-0.146). There was statistically significant relationship between MP values and hydroxychloroquine length of use and cumulative dose (p=0.027 and p=0.049, respectively). Duration of use was not associated with changes in 10/2 visual field (p=0.124). There were significant relationships between alterations in FAF and hydroxychloroquine length of use and cumulative dose (p=0.027 and p=0.049, respectively). Conclusion: FAF alterations were significantly associated with duration of hydroxychloroquine use and cumulative dose. As objective methods are more reliable, examinations such as FAF can be recommended as auxiliary methods in the follow-up and early detection of toxic maculopathy.


Assuntos
Hidroxicloroquina/efeitos adversos , Macula Lutea/patologia , Doenças Retinianas/induzido quimicamente , Acuidade Visual , Adulto , Idoso , Antirreumáticos/efeitos adversos , Doenças do Tecido Conjuntivo/tratamento farmacológico , Feminino , Angiofluoresceinografia , Seguimentos , Fundo de Olho , Humanos , Incidência , Macula Lutea/efeitos dos fármacos , Masculino , Pessoa de Meia-Idade , Doenças Retinianas/diagnóstico , Doenças Retinianas/epidemiologia , Células Ganglionares da Retina/efeitos dos fármacos , Células Ganglionares da Retina/patologia , Estudos Retrospectivos , Fatores de Tempo , Tomografia de Coerência Óptica , Turquia/epidemiologia , Campos Visuais/fisiologia , Adulto Jovem
12.
Rev Assoc Med Bras (1992) ; 65(5): 618-624, 2019 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-31166437

RESUMO

OBJECTIVE: In this study, we aimed to determine the extent of restless legs syndrome (RLS) in pregnant women and evaluate the relationship between the syndrome and quality of life. METHODS: This is a cross-sectional descriptive study. A questionnaire developed by the researcher, the Short Form 36 (SF-36) Questionnaire to measure the quality of life, the International Restless Legs Syndrome Study Group (IRLSSG) Diagnostic Criteria for RLS and the Restless Legs Syndrome Rating Scale were applied to the women to collect the data. A total of 250 pregnant women were included in the study. RESULTS: The mean age of the women was 28.11 ± 5.59 years and the mean gestational time was 26.26 ± 10.72 weeks. Symptoms of RLS were seen in 46.4 % of the women. The mean for the RLS Violence Rating Score was 20.82 ± 6.61 for the women with RLS. RLS was found to be mild in 5.2 % of the women, moderate in 45.7 %, severe in 40.5 % and very severe in 8.6 %. A statistically significant effect of RLS survival on quality of life was observed. CONCLUSION: These results indicate that almost half of the pregnant women in this study experienced RLS, and about half of those with RLS experienced severe or very severe RLS. There is a significant relationship between RLS and six domains of SF-36 (physical, role limitations, pain, general health perception, energy/vitality, and mental health).


Assuntos
Complicações na Gravidez/epidemiologia , Complicações na Gravidez/fisiopatologia , Qualidade de Vida , Síndrome das Pernas Inquietas/epidemiologia , Síndrome das Pernas Inquietas/fisiopatologia , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Pessoa de Meia-Idade , Gravidez , Prevalência , Índice de Gravidade de Doença , Estatísticas não Paramétricas , Inquéritos e Questionários , Turquia/epidemiologia , Adulto Jovem
13.
Rev Assoc Med Bras (1992) ; 65(5): 633-636, 2019 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-31166439

RESUMO

OBJECTIVE: Patients in intensive care units (ICU) have greater morbidity and mortality. We aimed to study neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in the ICU population. METHODS: Medical and laboratory data of patients treated in ICU were retrospectively analyzed. Patients were divided into deceased and survived groups. RESULTS: The NLR of survived and deceased groups were 3.6 (0.2-31) and 9.5 (1-40), respectively (p<0.001). The PLR of the survived group (111 [16-537]) was significantly lower than the PLR of the deceased (209 [52-1143]), (p<0.001). An NLR higher than 4.9 had 84% sensitivity and 67% specificity is selecting deceased patients (AUC:0.80, p<0.001). A PLR higher than 112 had 83% sensitivity and 52% specificity in predicting deadly cases (AUC:0.76, p<0.001). Both PLR and NLR were significantly and positively correlated with c reactive protein levels. CONCLUSION: We suggest that physicians should pay particular attention to the treatment of patients in ICU with elevated NLR and PLR.


Assuntos
Plaquetas , Mortalidade Hospitalar , Unidades de Terapia Intensiva/estatística & dados numéricos , Linfócitos , Neutrófilos , Adulto , Idoso , Idoso de 80 Anos ou mais , Proteína C-Reativa/análise , Feminino , Humanos , Contagem de Linfócitos , Masculino , Pessoa de Meia-Idade , Contagem de Plaquetas , Valor Preditivo dos Testes , Prognóstico , Curva ROC , Valores de Referência , Estudos Retrospectivos , Estatísticas não Paramétricas , Turquia/epidemiologia
14.
J Forensic Leg Med ; 66: 65-69, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31226501

RESUMO

In the last decade, the whole world has witnessed a chaotic process characterized by uprisings, revolutions, and wars in the Middle East. The Syrian civil war, with its local and global consequences, is the most destructive of these events. Social and economic aspects of the effects of the Syrian civil war were discussed in detail. However, the change in forensic postmortem case pattern of neighboring countries remains unclear. Here, we aim to discuss the effects of the Syrian civil war on forensic postmortem case patterns in Turkey as a neighboring country, with possible causes and suggestions. The postmortem case patterns of the 5-year period before the beginning of the Syrian war (2006-2011) and the next 5-year period after the start of the war (2012-2016) were investigated retrospectively. This aims to reveal the possible effects of the Syrian civil war on forensic postmortem case pattern of Turkey in relation to the assault deaths of statistics of Turkey. We found that explosion-related and firearm-related death cases significantly increased after the Syrian civil war. The dramatic increase in the explosion-related deaths can be attributed to terrorist attacks. Wounded civilians during the civil war were admitted to health units and hospitals in the south and southeast parts of Turkey, which consequently result in a crisis in the application of health services. There was no significant difference in Turkish death statistics, however forensic case pattern was affected.


Assuntos
Traumatismos por Explosões/mortalidade , Abuso Físico/tendências , Guerra , Ferimentos por Arma de Fogo/mortalidade , Humanos , Estudos Retrospectivos , Síria , Turquia/epidemiologia
15.
Niger J Clin Pract ; 22(6): 777-781, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31187761

RESUMO

Background: Sharp and penetrating object injuries (SPOIs) are seen frequently in forensic medicine practice. In this study, we aimed to retrospectively investigate cases with SPOIs. Materials and Methods: This study investigated the charts of patients treated at Adiyaman University Education and Research Hospital between January 1, 2013, and December 31, 2017. A total of 934 inpatients with sharp object injuries were included in the study. Data were assessed using a suitable computer-aided package program. Cases were examined in terms of age, gender, injury body site, suicide or homicide, radiologic findings, presence of vital danger, and severity of injury. Results: In this study, we examined the charts for 934 inpatients with stab wounds. It was stated that 124 (13.27%) of those injured were female and 810 (86.63%) male; the average age of the injured persons was 29.8 ± 18.2 years. It was found that 214 (22.91%) people were exposed to vital danger and that 720 (77.09%) suffered from soft tissue injuries (penetrating skin and muscle injuries). Also, 69.27% of the cases (n = 647) involved people less than 35 years of age. Conclusion: Considering that stab injuries are more frequent in the lower age groups, we believe that such injuries could be reduced by increasing training programs for young people.


Assuntos
Lesões dos Tecidos Moles/etiologia , Tentativa de Suicídio , Violência , Ferimentos Perfurantes/etiologia , Adolescente , Adulto , Fatores Etários , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Músculo Esquelético/lesões , Estudos Retrospectivos , Pele/lesões , Turquia/epidemiologia , Adulto Jovem
16.
Cancer Invest ; 37(4-5): 209-215, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31179764

RESUMO

This study aimed to determine incidence, risk factors of unplanned hospital visits children receiving chemotherapy. The study was conducted with 65 children. Data were collected using form consisting of questions regarding causes of their unplanned hospital visits. Chi-square test were used analysis of data. Three quarters of children receiving chemotherapy were determined to have unplanned hospital visits, majority of them were found to be admitted. Knowing high-risk factors for unplanned hospital visits and admissions of children receiving chemotherapy and applying appropriate interventions for discharge education and home care regarding these factors may contribute to reduce unplanned hospital visits.


Assuntos
Antineoplásicos/efeitos adversos , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/epidemiologia , Hospitalização/estatística & dados numéricos , Neoplasias/tratamento farmacológico , Adolescente , Criança , Pré-Escolar , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/etiologia , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/terapia , Feminino , Humanos , Incidência , Lactente , Recém-Nascido , Masculino , Educação de Pacientes como Assunto , Estudos Retrospectivos , Fatores de Risco , Turquia/epidemiologia
17.
Saudi Med J ; 40(6): 568-574, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31219491

RESUMO

OBJECTIVES:  To determine the prevalence of sarcopenia and related factors in individuals aged ≥65 years living in the Bornova district of Izmir, Turkey. Sarcopenia is one of the most serious health problems among elderly individuals. METHODS:  This cross-sectional study was conducted in the Bornova district of Izmir, Turkey, between February-July 2015. This study participants were comprised of 909 individuals aged ≥65 years. The dependent variable was the presence of sarcopenia and the European Working Group on Sarcopenia in Older People (EWGSOP) approach was used for determining sarcopenia. The independent variables were socio-demographic and economic characteristics, healthy life behaviors and health status/condition. Data were collected at home through face-to-face interviews and measurements, analysed using chi-square test, t-test and logistic regression analysis. RESULTS:  The participants' mean age was 72.8±6.2 (range: 65-100) years, and 60.2% were female (n=582). The prevalence of sarcopenia was 5.2% and that of low gait speed was 41.0%, low grip strength was 57.0%, low calf circumference was 6.1% and the combination of low gait speed and low grip strength was 14.3%. Risk factors of sarcopenia included increasing age, physical inactivity, low body mass index and the presence or risk of malnutritionConclusion: The prevalence of sarcopenia was 5.2% in this population and increased with age, physical inactivity, low body mass index and the presence or risk of malnutrition.


Assuntos
Sarcopenia/epidemiologia , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Índice de Massa Corporal , Distribuição de Qui-Quadrado , Estudos Transversais , Feminino , Comportamentos Relacionados com a Saúde , Nível de Saúde , Estilo de Vida Saudável , Humanos , Entrevistas como Assunto , Modelos Logísticos , Masculino , Desnutrição , Prevalência , Fatores de Risco , Sarcopenia/etiologia , Fatores Socioeconômicos , Turquia/epidemiologia
18.
J Med Microbiol ; 68(6): 874-881, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31116101

RESUMO

PURPOSE: To assess the antibiotic resistance, transposon profiles, serotype distribution and vaccine coverage rates in 110 erythromycin-resistant S. pneumoniae clinical isolates. METHODOLOGY: Erythromycin, clindamycin, tetracycline, chloramphenicol and kanamycin susceptibilities were assessed using the E-test/disc diffusion method. Inducible macrolide resistance was tested using the erythromycin-clindamycin double disc diffusion test. Serogrouping and serotyping were performed using latex particle agglutination and the Quellung reaction, respectively. Drug resistance genes and transposon-specific genes were investigated by PCR. RESULTS: Of the isolates, 93  % were resistant to clindamycin; 81  % were resistant to tetracycline; 76  % were multi-drug-resistant, having resistance to both clindamycin and tetracycline; and 12  % had extended-drug resistance, being resistant to clindamycin, tetracycline, chloramphenicol and kanamycin. The majority of isolates (88.2 %) exhibited the cMLSB phenotype. The association between the cMLSB phenotype and tetracycline resistance was related to transposons Tn2010 (38.2 %), Tn6002 (21.8 %) and Tn3872 (18.2 %). M and iMLSB phenotypes were observed in 7 and 5  % of the isolates, respectively. The most frequent serotype was 19 F (40 %). Among the erythromycin-resistant pneumococci, vaccine coverage rates for the 13-valent pneumococcal conjugate vaccine (PCV-13) and the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) were 76.4 and 79.1  %, respectively, compared to 82.2 and 85.1 % transposon-carrying isolates. CONCLUSIONS: Multi-drug resistance among erythromycin-resistant S. pneumoniae isolates mainly occurs due to the horizontal spread of the Tn916 family of transposons. The majority of the transposon-carrying isolates are covered by 13- and 23-valent pneumococcal vaccines. Since serotype distribution and transposons in S. pneumoniae isolates may change over time, close monitoring is essential.


Assuntos
Antibacterianos/farmacologia , Farmacorresistência Bacteriana Múltipla , Eritromicina/farmacologia , Infecções Pneumocócicas/microbiologia , Streptococcus pneumoniae/genética , Cápsulas Bacterianas/imunologia , Elementos de DNA Transponíveis/genética , Genótipo , Humanos , Fenótipo , Infecções Pneumocócicas/tratamento farmacológico , Infecções Pneumocócicas/epidemiologia , Vacinas Pneumocócicas , Sorogrupo , Streptococcus pneumoniae/imunologia , Turquia/epidemiologia
19.
Diabetes Res Clin Pract ; 152: 119-124, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31121273

RESUMO

AIMS: Diabetes mellitus is one of the most significant global health emergencies of the 21st century. Every year, an increasing number of people succumb to the condition and therefore suffer life-changing complications. So management of this disease has an important role to prevent complications. In this study, our objective is to assess the quality of guidelines related to the significant public health problem diabetes that have been developed by international and national organizations using the AGREE II tool. METHODS: This observational study assesses the quality of clinical practice guidelines used in the management of diabetes with AGREE II tool. Statistical analysis was performed using the SPSS 20 program package. RESULTS: The overall quality score of the guidelines ranges between 3 and 6.25. While NICE's guidelines scored the highest, the guidelines of the National Diabetes Foundation scored the lowest. CONCLUSION: More comprehensive studies are needed for assessing the quality of guidelines in every subject.


Assuntos
Diabetes Mellitus Tipo 2/terapia , Guias de Prática Clínica como Assunto/normas , Garantia da Qualidade dos Cuidados de Saúde , Assistência Integral à Saúde/normas , Diabetes Mellitus Tipo 2/epidemiologia , Estudos de Avaliação como Assunto , Humanos , Qualidade da Assistência à Saúde/normas , Projetos de Pesquisa , Turquia/epidemiologia
20.
Pediatr Surg Int ; 35(7): 803-806, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31037325

RESUMO

PURPOSE: We aim to evaluate the sociodemographic and medical features of child-aged refugee patients and identify their health-related problems. METHODS: Refugee children admitted to pediatric surgery department of a teaching hospital during the years 2012-2017 were included. Patients' files were reviewed retrospectively for sociodemographic and medical features. RESULTS: A total of 254 patients with the mean age of 4.6 ± 4.15 years (0-16 years) were treated. Male-to-female ratio was 1.7. Most common diagnosis were inguino-scrotal pathologies (n = 50, 19.7%) followed by foreign body ingestion (n = 37, 14.6%) and corrosive esophagitis (n = 22, 8.7%). The cause of admission was a potentially preventable trauma in 24.4% of cases. Comorbid medical conditions were present in 49 patients (19.3%). Anemia was detected in 23.2% of cases. Weight according to age and gender were < 3 percentile in 29.1% of patients. Difficulties in communication, lack of former medical history and advanced presentation of disease were the challenges faced by caregivers. CONCLUSION: The primary diagnoses for admission of refugee children were different from the routine practice and a significant part were from preventable causes. Comorbidities were common potentially having a negative influence on treatment processes. This can be a result of unfavorable living conditions and lack of medical care during migration.


Assuntos
Conflitos Armados , Doenças do Sistema Digestório/etnologia , Nível de Saúde , Hospitais de Ensino/estatística & dados numéricos , Refugiados , Procedimentos Cirúrgicos Operatórios , Adolescente , Criança , Pré-Escolar , Estudos Transversais , Doenças do Sistema Digestório/cirurgia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Morbidade/tendências , Estudos Retrospectivos , Síria/etnologia , Turquia/epidemiologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA