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1.
Int. j. high dilution res ; 17(3/4): 42-57, 2018.
Artigo em Inglês | LILACS, HomeoIndex - Homeopatia | ID: biblio-1050010

RESUMO

Background: Clinical studies have shown that adverse events in early life are quite stressful and can lead to the development of psychiatric disorders, such as anxiety, in adolescence and adulthood in humans. Experimental models of maternal deprivation (MD) in rats can be a useful tool for the understanding how these events in the early period of development can lead to behavioral changes in adulthood. Aims: The objective of this study was to evaluate the long-term effects of Zincum metallicum (Zinc met) homeopathic treatment in rats subjected to maternal deprivation (MD) in their early days of life. Methods: Newborn female rats were subjected to MD during 10 days, one hour per day, from PND10 to PND21, and treated from the 10th day of lactation (PND10) up to weaning (PND21). On the PND21 the rats were divided in 4 groups (N=8): a) treated with Zinc met 30c; b) treated with Zinc met 6c; c) treated with 10% hydroalcoholic solution (HS); and "blank control", rats without any treatment nor experienced deprivation (ND). The medicines were administered in blind trials, identified by codes. The animals were weighed weekly, from weaning until the end of the experiment, and evaluated in the Open Field (OF) and in the Elevated Plus Maze (EPM) devices, to evaluate mobility, emotionality and anxiety, in 3 moments of life: in PND21 (childhood), during puberty (PND 40) and adulthood (PND75). Data were analyzed statistically by ANOVA, followed by the Bonferroni's Multiple Comparison Test, being p≤0.05. Results: 1) relative to ND group the Zinc met 6c showed reduced body weight while no differences were observed between the other groups; 2) In the OF, the MD group showed increased rearing behavior at PND 40. The Zinc met 6c group reversed this effect showing similar profile as the ND group. Moreover, Zinc met 6c group showed increase in the immobility time at this age; 3) In the EPM, the MD group showed increased time in closed arms and decreased head dips relative to ND group in PND21 period of observation. Treatment with Zinc met 6c but not with Zinc met 30c was effective to reduce this anxiety-like behavior in PND21. Conclusion: According to the proposed model, Zincum metallicum 6c seems to be able to prevent in anxiety-like behavior induced by maternal deprivation in the childhood, mainly in behavioral models related to anxiety. However, other studies still need to be developed to understand the physio-pathological basis of these effects. (AU)


Assuntos
Animais , Ratos , Transtornos de Ansiedade , Zincum Metallicum/uso terapêutico , Homeopatia , Privação Materna
2.
Int. j. high dilution res ; 16(1): 7-19, 2017. tab, graf
Artigo em Inglês | HomeoIndex - Homeopatia | ID: hom-12091

RESUMO

Cicatrization can be divided into three phases: inflammation, fibroblastic, maturation and remodeling [1]. The extracellular matrix may be replaced by a stronger and more elastic connective tissue. In a scar collagen is the major component of the mature connective tissue [2]. In homeopathic area, the greater is the investigated segment ultra dilutions [6]. However, little research has been done to explore the effect of dynamized drugs in in vitro cell culture [4]. Using the Zincum metallicum 6CH and Calendula officinalis 6CH applied independently in different concentrations in fibroblast cultures sought to determine the increase in proliferative activity using techniques such as IC50, MTT, flow cytometry and quantification of collagen. As expected from the literature, ie both homeopathic according to the literature are used for treatments that Require skin healing, both showed increased proliferative activity, having Calendula most cellular response, presenting as cell cycle stimulating checked via flow cytometry.(AU)


Assuntos
Humanos , Cicatrização , Zincum Metallicum/uso terapêutico , Calendula/uso terapêutico , Altas Potências , Fibroblastos
3.
Int. j. high dilution res ; 16(1): 7-19, 2017. tab, ilus
Artigo em Inglês | LILACS | ID: biblio-972910

RESUMO

Cicatrization can be divided into three phases: inflammation, fibroblastic, maturation and remodeling [1]. The extracellular matrix may be replaced by a stronger and more elastic connective tissue. In a scar collagen is the major component of the mature connective tissue [2]. In homeopathic area, the greater is the investigated segment ultra dilutions [6]. However, little research has been done to explore the effect of dynamized drugs in in vitro cell culture [4]. Using the Zincum metallicum 6CH and Calendula officinalis 6CH applied independently in different concentrations in fibroblast cultures sought to determine the increase in proliferative activity using techniques such as IC50, MTT, flow cytometry and quantification of collagen. As expected from the literature, ie both homeopathic according to the literature are used for treatments that Require skin healing, both showed increased proliferative activity, having Calendula most cellular response, presenting as cell cycle stimulating checked via flow cytometry.


Assuntos
Humanos , Cicatrização , Zincum Metallicum/uso terapêutico , Calendula/uso terapêutico , Altas Potências , Fibroblastos
4.
Rev. homeopatia (São Paulo) ; 79(1/2): 36-41, 2016. ilus
Artigo em Inglês, Português | HomeoIndex - Homeopatia | ID: hom-11260

RESUMO

Transtornos da personalidade são um grupo de condições caracterizadas por incapacidade para se relacionar com outras pessoas e aprender da experiência. Sujeitos com transtornos da personalidade podem vir a perceber que as suas crenças e atitudes são diferentes daquelas da maioria das pessoas. Outros descobrem que a sua conduta é inusual, inesperada e mesmo ofensiva. No presente artigo é discutido o caso de um paciente de sexo masculino e 42 anos de idade com transtorno esquizotípico, tendo a alucinação típica de ser sujeito de abuso e perseguição, e posterior sensação de formigamento. Com o medicamento homeopático corretamente selecionado a autoconfiança, sintomas somáticos, estresse e preocupação, ansiedade e alucinações melhoraram, o que sugere que a homeopatia pode ser muito útil no tratamento deste tipo de transtornos da personalidade. (AU)


Personality disorders are a group of conditions characterized by an inability to get on with other people and learn from experience. People with a personality disorder may find that their beliefs and attitudes are different from those of most other people. Others may find their behavior unusual, unexpected or perhaps offensive. In this paper, we discuss a case of a 42- year-old man with schizotypal personality disorder with typical delusions of being abused and persecuted and subsequent formication. With a properly selected homoeopathic medicine the patient experienced symptom improvement in self-confidence, somatic complaints, stress and worry, anxiety, and delusions, suggesting that homoeopathy is quite useful in the treatment of such personality disorders. (AU)


Assuntos
Humanos , Masculino , Adulto , Zincum Metallicum/uso terapêutico , Homeopatia , Transtorno da Personalidade Esquizotípica , Transtornos Psicóticos
5.
Rev. homeopatia (Säo Paulo) ; 79(1/2): 36-41, 2016. ilus
Artigo em Inglês, Português | LILACS | ID: lil-788869

RESUMO

Transtornos da personalidade são um grupo de condições caracterizadas por incapacidade para se relacionar com outras pessoas e aprender da experiência. Sujeitos com transtornos da personalidade podem vir a perceber que as suas crenças e atitudes são diferentes daquelas da maioria das pessoas. Outros descobrem que a sua conduta é inusual, inesperada e mesmo ofensiva. No presente artigo é discutido o caso de um paciente de sexo masculino e 42 anos de idade com transtorno esquizotípico, tendo a alucinação típica de ser sujeito de abuso e perseguição, e posterior sensação de formigamento. Com o medicamento homeopático corretamente selecionado a autoconfiança, sintomas somáticos, estresse e preocupação, ansiedade e alucinações melhoraram, o que sugere que a homeopatia pode ser muito útil no tratamento deste tipo de transtornos da personalidade...


Personality disorders are a group of conditions characterized by an inability to get on with other people and learn from experience. People with a personality disorder may find that their beliefs and attitudes are different from those of most other people. Others may find their behavior unusual, unexpected or perhaps offensive. In this paper, we discuss a case of a 42- year-old man with schizotypal personality disorder with typical delusions of being abused and persecuted and subsequent formication. With a properly selected homoeopathic medicine the patient experienced symptom improvement in self-confidence, somatic complaints, stress and worry, anxiety, and delusions, suggesting that homoeopathy is quite useful in the treatment of such personality disorders...


Assuntos
Humanos , Masculino , Adulto , Homeopatia , Transtorno da Personalidade Esquizotípica , Zincum Metallicum/uso terapêutico , Transtornos Psicóticos
6.
Int. j. high dilution res ; 10(35): 84-90, june 30, 2011.
Artigo em Inglês | LILACS-Express | HomeoIndex - Homeopatia | ID: hom-10655

RESUMO

Introduction: Based on the large amount of patients that seek alternative treatment for clinical complaints compatible with ADHD diagnosis and above all by the high percentage of non adaptation or risk that officially proposed drugs may bring, we developed a laboratorial clinical investigative profile that favors a safe homeopathic treatment.Material: 52 cases with urinary zinc analysis, with ADHD diagnosis.Method: using the diagnosis confirmation questionnaire (SNAP-IV by UFRJ) and Zinc analysis by HPLC method (high performance liquid chromatography) which normal values range from 246 and 846 nmol/liter.Results: in a 52 patients (table 1) sampling with a suggestive ADHD diagnosis, we obtained a quantitative alteration in 31 cases showing high urinary Zinc levels, which allowed therapeutic approach that lead to better clinical result followed by subsequent reduction of urinary Zinc levels, in posterior analysis in eight (8) of these patients.(AU)


Assuntos
Humanos , Transtorno do Deficit de Atenção com Hiperatividade , Zincum Metallicum
7.
Int. j. high dilution res ; 10(35): 82-83, june 30, 2011.
Artigo em Inglês | LILACS-Express | HomeoIndex - Homeopatia | ID: hom-10656

RESUMO

The objective of this study, stated as Previous Notation, is to demonstrate that Attention Deficit Hyperactivity Disorder Pathology presents a differentiated condition in carriers where a significant percentage, close to 60%, present a higher level of zinc elimination by kidneys. In this study, a direct relation of Zinc Mettalicum pathogenetic symptoms, this disturbance and the elimination of this element which participates in neurotransmission process were identified, and the relation with elements from regular diet, which can act as zinc chelating agents would be involved in the evolution of this disturbance, justifying the issue of individual susceptibility, essential in homeopathic investigation. Keywords: Attention; Impulsivity; Agitation; Zincum Mettalicum; Neurotransmission.(AU)


Assuntos
Humanos , Transtorno do Deficit de Atenção com Hiperatividade , Zincum Metallicum
8.
Braz. j. microbiol ; 40(4): 838-845, Oct.-Dec. 2009. graf, tab
Artigo em Inglês | LILACS | ID: lil-528166

RESUMO

Cadmium (Cd) is a major environmental hazard, which usually is detected in its ionic form of Cd2+. It also causes adverse toxic effects on human health and other living organisms. Cd-resistant bacteria were isolated from Cd-contaminated soils. One isolate, TAK1, was highly resistance level to Cd toxicity. TAK1 was isolated from soil contaminated with a high Cd concentration (204.1 mg.kg-1). The result of 16S rDNA sequence analysis found that the TAK1 showed the similarity to Ralstonia sp. Physiological adaptive and cross-protective responses to Cd and Zn killing were investigated in Ralstonia sp.TAK1. Exposure to a low concentration of Cd induced adaptive resistance to higher concentrations of Cd. In addition, pretreatment of Ralstonia sp.TAK1 with an inducing concentration of Cd conferred cross-protective response against subsequent exposure to the lethal concentrations of Zn. The induced adaptive and cross-protective response Ralstonia sp.TAK1 required newly synthesized protein(s). Cd-induced adaptive and cross-protective responses against Cd and Zn toxicity are the important mechanisms used by Ralstonia sp.TAK1 to survive in the heavy metal contaminated environments. These findings might lead to the use of Ralstonia sp.TAK1 for microbial based remediation in Cd and Zn-contaminated soils.


Assuntos
Cadmium Metallicum/isolamento & purificação , Cadmium Metallicum/toxicidade , Técnicas In Vitro , RNA , Análise de Sequência de DNA , Toxicidade , Zincum Metallicum/isolamento & purificação , Zincum Metallicum/toxicidade , Poluição Ambiental , Meio Ambiente , Métodos , Solo , Métodos
9.
11.
Homeopatia Méx ; 75(641): 62-67, marc.-abr.2006.
Artigo em Espanhol | HomeoIndex - Homeopatia | ID: hom-8055

RESUMO

Se realizó un estudio observacional descriptivo con el objetivo de mostrar el resultados del tratamiento conservador en un grupo de pacientes con Insuficiencia Arterial Crónica (IAC) sin criterios de operabilidad, atendidos en el servicio de Angiología del Hospital Provincial"Manuel Ascunce D." y seguidos en la consulta de Homeopatía de la Clínica de la Universidad Médica "Carlos J. Finlay", en el período comprendido entre Noviembro del 2004 a Julio 2005.(AU)


Assuntos
Pessoa de Meia-Idade , Claudicação Intermitente , Arteriopatias Oclusivas , Inibidores da Agregação Plaquetária , Arnica , Hypericum , Zincum Metallicum , Homeopatia , Tomografia , Diabetes Mellitus , Tabagismo
12.
Homeopatia Méx ; 75(641): 62-67, marc.-abr.2006.
Artigo em Espanhol | LILACS | ID: lil-514414

RESUMO

Se realizó un estudio observacional descriptivo con el objetivo de mostrar el resultados del tratamiento conservador en un grupo de pacientes con Insuficiencia Arterial Crónica (IAC) sin criterios de operabilidad, atendidos en el servicio de Angiología del Hospital Provincial"Manuel Ascunce D." y seguidos en la consulta de Homeopatía de la Clínica de la Universidad Médica "Carlos J. Finlay", en el período comprendido entre Noviembro del 2004 a Julio 2005.


Assuntos
Pessoa de Meia-Idade , Arnica , Arteriopatias Oclusivas , Hypericum , Claudicação Intermitente , Inibidores da Agregação Plaquetária , Zincum Metallicum , Diabetes Mellitus , Homeopatia , Tabagismo , Tomografia
13.
Rev. homeopatia (Sao Paulo) ; 69(1/4): 27-38, 2004. ilus, tab, graf
Artigo em Português | HomeoIndex - Homeopatia | ID: hom-7695

RESUMO

Essa dissertacao apresenta, com o apoio de fundamentacao teorico-pratica, o cenario em que se insere a problematica em questao: o efeito antioxidante in vitro dos medicamentos homopaticos Arsenicum album, Cuprum metallicum, Manganum e Zincum metallicum


Assuntos
Antioxidantes , Terapia Ortomolecular , Arsenicum Album , Cuprum Metallicum , Zincum Metallicum , Manganum Aceticum , Pesquisa Homeopática Básica
14.
Rev. homeopatia (Säo Paulo) ; 69(1/4): 27-38, 2004. ilus, tab, graf
Artigo em Português | LILACS | ID: lil-496968

RESUMO

Essa dissertacao apresenta, com o apoio de fundamentacao teorico-pratica, o cenario em que se insere a problematica em questao: o efeito antioxidante in vitro dos medicamentos homopaticos Arsenicum album, Cuprum metallicum, Manganum e Zincum metallicum


Assuntos
Antioxidantes , Arsenicum Album , Pesquisa Homeopática Básica , Cuprum Metallicum , Manganum Aceticum , Terapia Ortomolecular , Zincum Metallicum
18.
Acta Homoepathica Argentinensia ; 23(68): 37-42, 2002.
Artigo em Espanhol | HomeoIndex - Homeopatia | ID: hom-12349

RESUMO

Segun Cirlot, en el Zohar, la "cabeza mágica" simboliza luz astral;en el arte medieval simboliza la mente y la vida espiritualEm su Timeo, Platon dice: "la cabeza humana es la imagem del mundo".


Assuntos
Zincum Metallicum , Materia Medica
19.
Acta Homoepathica Argentinensia ; 23(68): 45-49, 2002.
Artigo em Espanhol | HomeoIndex - Homeopatia | ID: hom-12350

RESUMO

La figura del diablo para los psiquiatras junguianos,representa la parte sombria de nosotros mismos, habita en las zonas oscuras de nuestra psique.El diablo medio hombre y medio bestia, describe el aspecto siniestro y grotesco de nuestro inconsciente, con el que nunca hemos legado a un contacto real.


Assuntos
Zincum Metallicum , Materia Medica
20.
Acta Homoepathica Argentinensia ; 23(68): 51-54, 2002.
Artigo em Espanhol | HomeoIndex - Homeopatia | ID: hom-12351

RESUMO

Primero hare una breve resenã de los sintomas clínicos de la intoxicacion con monoxido de carbono.


Assuntos
Zincum Metallicum , Materia Medica
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