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1.
Rev. enferm. UERJ ; 28: 49570, jan.-dez. 2020.
Article in English, Portuguese | LILACS, BDENF - Nursing | ID: biblio-1094832

ABSTRACT

Objetivo: discutir as experiências e contradições no controle da pandemia de Covid-19 sob a perspectiva da epidemiologia e das políticas públicas brasileiras. Conteúdo: o debate apresentado divide-se em duas seções: a primeira traça a reflexão dos parâmetros epidemiológicos sobre a curva epidêmica do SARS-CoV-2, bem como as experiências internacionais para o controle deste fenômeno. A segunda, ancorada nas políticas públicas brasileiras, apresenta uma análise comparada das experiências nacionais e internacionais, discutindo os potenciais reflexos sobre a pandemia, considerando algumas especificidades sociais. Conclusão: frente à impossibilidade de redução de pessoas susceptíveis por meio de estratégias vacinais, a redução da velocidade da curva epidêmica precisa ocorrer por meio de ações de isolamento físico social. Ademais, a construção de políticas públicas que visem a proteção ao trabalhador e a ampliação do investimento no setor saúde são medidas urgentes.


Objective: to discuss experiences and contradictions in the control of the Covid-19 pandemic from the perspective of epidemiology and Brazilian public policies. Content: the discussion presented is divided into two sections: the first one present epidemiological parameters on the epidemic curve of SARS-CoV-2, as well as the international experiences for the control of this phenomenon. The second, anchored in the Brazilian public policies, presents a comparative analysis of national and international experiences, discussing the potential impacts on the pandemic, considering some specific social issues. Conclusion: in the face of impossibility of reducing susceptible people through vaccination strategies, the reduction of the speed of the epidemic curve needs to occur through actions of social distance. In addition, the construction of public policies aimed at protecting workers and expanding investment in the health sector are urgent measures.


Objetivo: discutir las experiencias y contradicciones en el control de la pandemia Covid-19 desde la perspectiva de la epidemiología brasileña y las políticas públicas. Contenido: el debate presentado se divide en dos secciones. El primero traza la reflexión de los parámetros epidemiológicos en la curva epidémica del SARS-CoV-2, así como las experiencias internacionales para el control de este fenómeno. El segunda seccione, anclada en las políticas públicas brasileñas, presenta un análisis comparativo de las experiencias nacionales e internacionales, discutiendo los posibles impactos en la pandemia, considerando algunas especificidades sociales brasileñas. Conclusión: dada la imposibilidad de reducir a las personas susceptibles a través de estrategias de vacunación, la reducción de la velocidad de la curva epidémica debe ocurrir a través de acciones de aislamiento social y físico. Además, la construcción de políticas públicas destinadas a proteger a los trabajadores y ampliar la inversión en el sector de la salud son medidas urgentes.


Subject(s)
Humans , Pneumonia, Viral , Coronavirus Infections/economics , Coronavirus Infections/epidemiology , Public Health Policy , Pandemics , Public Policy , Betacoronavirus
2.
Estima (Online) ; 18(1): e0120, jan.-dez. 2020. ilus
Article in Portuguese | BDENF - Nursing | ID: biblio-1096183

ABSTRACT

Diante do número de casos de infecção pelo coronavírus (COVID-19), a Organização Mundial da Saúde (OMS) declarou que a doença se trata de uma pandemia de alerta e mobilização mundial, estando presente em vários países e continentes. No Brasil, a pandemia chegou no final de fevereiro de 2020 e vem causando alerta pelo aumento no número de contaminados relacionado com a alta capacidade de transmissão da doença. Nos doentes acometidos, o vírus pode causar desde sintomas simples, que podem ser tratados em casa, até internações hospitalares, assistência em unidades de terapia intensiva e pode inclusive levar à morte.

3.
Estima (Online) ; 18(1): e0120, jan.-dez. 2020. ilus
Article in Spanish | BDENF - Nursing | ID: biblio-1096185

ABSTRACT

Ante el número de casos de infección por el coronavirus (COVID-19), la Organización Mundial de la Salud (OMS) declaró que la enfermedad se trata de una pandemia de alarma y movilización mundial, estando presente en varios países y continentes. En Brasil, la pandemia llegó a finales de febrero del 2020 y está causando alarma por el aumento en el número de contaminados relacionado con la alta capacidad de transmisión de la enfermedad. En los enfermos afectados el virus puede causar desde síntomas simples, que pueden ser tratados en casa, hasta ingresos hospitalarios, asistencia en unidades de terapia intensiva y puede incluso llevar a la muerte.

4.
Kasmera ; 48(1): e48102042020, ene-jun 2020.
Article in Spanish | LILACS-Express | ID: biblio-1087715

ABSTRACT

El nuevo coronavirus (2019-nCoV, SARS-CoV-2 o COVID-19) que hasta el momento ha afectado a más de 180 países de casi todos los continentes, fue declarado por la Organización Mundial de la Salud como pandemia por su alcance mundial y hasta la fecha, ha sobrepasado el millón de casos de infectados, de los cuales el 5,54% han sido letales. La emergencia de esta enfermedad, se ha explicado por el surgimiento de un coronavirus humano desconocido con incrementados factores de virulencia. El número exponencialmente creciente de casos en el mundo, refleja en parte la rápida transmisión del COVID-19, que se traduce en una dura prueba para los sistemas de salud de los países más afectados. Los retos que ha representado esta pandemia, muchos han tenido sus bases en las lecciones aprendidas de la pandemia de SARS en 2003 y dado el parecido genómico de esta nueva cepa de coronavirus, ha sido designado como SARS-CoV-2. No obstante, los parecidos, hay muchas preguntas aun por responder, especialmente en lo que respecta a los mecanismos de transmisión. Contar con datos detallados y precisos permitirá comprender y hacer un seguimiento del alcance de esta pandemia y fortalecer los esfuerzos de prevención y respuesta, en virtud que hasta el momento los tratamientos son experimentales y la vacuna podría estar disponible a mediano o largo plazo.


The new coronavirus (2019-nCoV, SARS-CoV-2 or COVID-19), which so far has affected more than 180 countries on almost every continent, was declared a pandemic by the World Health Organization. its global reach and to date, has exceeded one million infected cases, of which 5.54% have been fatal. The emergence of this disease has been explained by the presence of an unknown human coronavirus with increased virulence factors. The exponentially increasing number of cases in the world reflects in part the rapid transmission of COVID-19, which translates into a severe test for the health systems of the most affected countries. The challenges that this pandemic has represented, many have been based on the lessons learned from the SARS pandemic in 2003 and given the genomic similarity of this new strain of coronavirus, it has been designated as SARS-CoV-2. However, the like, there are many questions still to be answered, especially with regard to transmission mechanisms. Having detailed and accurate data will make it possible to understand and monitor the scope of this pandemic and strengthen prevention and response efforts, since the treatments are so far experimental and the vaccine may be available in the medium or long term.

10.
Ars pharm ; 61(2): 63-79, abr.-jun. 2020. tab, ilus, graf
Article in Spanish | IBECS | ID: ibc-188101

ABSTRACT

INTRODUCCIÓN: En diciembre de 2019, se detectaron los primeros casos de enfermedad respiratoria causada por un coronavirus emergente, al que se denominó SARS-CoV-2, que en los primeros meses de 2020 se ha extendido por todo el mundo con características de pandemia. MÉTODO: Se examinaron las publicaciones más relevantes en relación con los objetivos de la revisión. RESULTADOS: La enfermedad, conocida como COVID-19, cursa con tos, fiebre y dificultad respiratoria. Las formas más graves, que afectan principalmente a personas de edad avanzada y con determinadas comorbilidades, se manifiestan por afectación de la función respiratoria, que requiere ventilación mecánica, y síndrome de respuesta inflamatoria sistémica, que puede conducir a un choque séptico con fallo multiorgánico, y altas tasas de mortalidad. En esta revisión se examina el estado actual de conocimientos sobre las características y origen del SARS-CoV-2, su replicación, y la patogénesis, clínica, diagnóstico, tratamiento y prevención de COVID-19. CONCLUSIONES: Las características del SARS-CoV-2 y la clínica de COVID-19 son bien conocidas. La PCR es la técnica de referencia para el diagnóstico de laboratorio; se dispone de ensayos para detección de antígenos y de anticuerpos, con margen de optimización. Los protocolos de tratamiento incluyen la corrección de la respuesta inflamatoria sistémica y administración de agentes antivirales. Existen vacunas en desarrollo


INTRODUCTION: In December 2019, the first cases of respiratory disease caused by an emerging coronavirus were detected. The causative agento f the outbreak was called SARS-CoV-2, and in the first months of 2020 it spread throughout the world as a pandemic. METHOD: The most relevant publications concerned with the aims of the review were examined. RESULTS: The disease, known as COVID-19. Patients show cough, fever, and respiratory distress. The most severe forms, mainly affecting the elderly and associated with various comorbidities, are manifested by impaired respiratory function, requiring mechanical ventilation, and systemic inflammatory response syndrome, which can lead to septic shock with multi-organ failure and high mortality rates. This review examines the current state of knowledge about the characteristics and origin of SARS-CoV-2, its replication, and the pathogenesis, clinical, diagnosis, treatment, and prevention of COVID-19. CONCLUSIONS: The characteristics of SARS-CoV-2 and the clinical manifestations of COVID-19 are well known. PCR is the reference technique for laboratory diagnosis; assays for the detection of antigens and antibodies are available, with optimization possibilities. Treatment protocols include attenuation of the systemic inflammatory response and administration of antiviral agents. There are vaccines in development


Subject(s)
Humans , Coronavirus Infections , Pneumonia, Viral , Betacoronavirus/pathogenicity , Pandemics , Coronavirus Infections/diagnosis , Coronavirus Infections/prevention & control , Coronavirus Infections/therapy , Pneumonia, Viral/diagnosis , Pneumonia, Viral/prevention & control , Pneumonia, Viral/therapy
11.
Ars pharm ; 61(2): 145-148, abr.-jun. 2020.
Article in Spanish | IBECS | ID: ibc-188102

ABSTRACT

El coronavirus 2019 (SARS-CoV-2) ha sido declarado una emergencia de salud pública de impacto internacional por la Organización Mundial de la Salud. Debido a la aparición repentina de este proceso pandémico asociado con alta morbilidad y la mortalidad en todo el mundo, se han implementado varios tratamientos en los pacientes aquejados con esta dolencia. En este marco, comenzaron a usarse en pacientes críticos altas dosis de vitamina C. En este trabajo, analizamos los ensayos clínicos y / o trabajos de investigación disponibles en la literatura. Aunque se necesita más evidencia sobre su efectividad, es importante que el especialista comprenda la lógica clínica de este uso para determinar si es correcto como tratamiento concomitante. Conclusiones: El uso de altas dosis de vitamina C por vía parenteral parece ser una alternativa segura, disponible y económica, especialmente para pacientes críticos


The 2019 coronavirus (SARS-CoV-2) has been declared a public health emergency of international concern by the World Health Organization. Due to the sudden appearance of this pandemic process associated with increasing morbidity and mortality worldwide, various treatments have been implemented. In this framework, high doses of vitamin C began to be used in critically ill patients. We analyze the clinical trials and/or research papers available in the literature. Although more evidence on its effectiveness is needed is important for the specialist to understand the clinical logic of this use to determine if it is correct as a concomitant treatment. Conclusions: It seems that using high doses of vitamin C parenterally is a safe, available and economical alternative especially for critically ill patients


Subject(s)
Humans , Ascorbic Acid/administration & dosage , Coronavirus Infections/drug therapy , Pneumonia, Viral/drug therapy , Betacoronavirus , Pandemics , Evidence-Based Medicine , Clinical Trials as Topic , Infusions, Parenteral , Critical Illness
12.
Internet resource in Portuguese | LIS -Health Information Locator | ID: lis-LISBR1.1-47448

ABSTRACT

Estudo conduzido por Chen e publicado na revista Lancet avaliou a potencial transmissão vertical da infecção por COVID-19. Para isso foram avaliadas 9 gestantes diagnosticadas com pneumonia por COVID-19 através de seus dados clínicos, laboratoriais, e TC pulmonar.


Subject(s)
Breast Feeding , Betacoronavirus , Pneumonia, Viral , Coronavirus Infections , Infectious Disease Transmission, Vertical
13.
Internet resource in Portuguese | LIS -Health Information Locator, LIS-CONASS | ID: lis-LISBR1.1-47407

ABSTRACT

Este curso tem o objetivo de esclarecer aos profissionais de saúde qual o impacto ventilatório da COVID-19 e seus possíveis desfechos e estratégias ventilatórias.


Subject(s)
Coronavirus Infections/epidemiology , Pneumonia, Viral/epidemiology , Betacoronavirus , Epidemics/statistics & numerical data , Brazil/epidemiology
14.
Internet resource in Portuguese | LIS -Health Information Locator | ID: lis-LISBR1.1-47374

ABSTRACT

Este mapa apresenta uma visão geral da evidência sobre a aplicação das MTCI com base na caracterização de 125 estudos de revisão e estudos clínicos controlados, distribuídos em uma matriz com 57 intervenções sobre uma série de desfechos clínicos agrupados em 3 categorias: Melhora da imunidade/efeito antiviral para vírus respiratórios; Manejo complementar dos sintomas de infecções respiratórias; e Contribuições à Saúde Mental/Emocional em situações de trauma. As intervenções representam especialmente medicamentos fitoterápicos, medicina e terapias tradicionais chinesas, terapias mente-corpo como meditação e yoga, probióticos e outros suplementos nutricionais além de formulações dinamizadas da homeopatia.


Subject(s)
Betacoronavirus , Pneumonia, Viral/prevention & control , Pneumonia, Viral/epidemiology , Pneumonia, Viral/therapy , Coronavirus Infections/epidemiology , Coronavirus Infections/therapy , Coronavirus Infections/prevention & control , Pandemics/prevention & control , Treatment Outcome , Evidence-Based Medicine/methods , Medicine, Chinese Traditional/methods
15.
Internet resource in Spanish | LIS -Health Information Locator | ID: lis-LISBR1.1-47375

ABSTRACT

Este mapa presenta una visión general sobre posibles contribuciones de las MTCI a varias dimensiones de la pandemia por COVID-19. Dichas contribuciones se organizaron en tres categorías: Mejora de la inmunidad y efecto antiviral ante diferentes virus respiratorios; tratamiento complementario de los síntomas de las infecciones respiratorias; y salud mental en situaciones de crisis. Para el mapa se caracterizaron 125 estudios de revisión y estudios clínicos controlados, distribuidos en una matriz con 57 intervenciones para las tres categorías mencionadas. Las intervenciones representan especialmente medicinas herbales/ fitoterapia, medicina tradicional china, terapias de cuerpo-mente como la meditación y el yoga, probióticos y otros suplementos nutricionales además de formulaciones de homeopatía.


Subject(s)
Betacoronavirus , Pneumonia, Viral/prevention & control , Pneumonia, Viral/epidemiology , Pneumonia, Viral/therapy , Coronavirus Infections/epidemiology , Coronavirus Infections/therapy , Coronavirus Infections/prevention & control , Pandemics/prevention & control , Treatment Outcome , Evidence-Based Medicine/methods , Medicine, Chinese Traditional/methods
16.
Internet resource in English | LIS -Health Information Locator | ID: lis-LISBR1.1-47376

ABSTRACT

This map presents an overview of the evidence on the application of TCIM based on the characterization of 125 review studies and controlled clinical studies distributed in a matrix with 57 interventions on a series of clinical outcomes grouped into 3 major categories: Improved immunity/antiviral effect for respiratory viruses; Complementary management of symptoms of respiratory infections; and Mental health. The interventions represent especially herbal medicines, traditional Chinese medicine and therapies, mind-body therapies like meditation and yoga, probiotics and other nutritional supplements besides homeopathy formulations.


Subject(s)
Betacoronavirus , Pneumonia, Viral/prevention & control , Pneumonia, Viral/epidemiology , Pneumonia, Viral/therapy , Coronavirus Infections/epidemiology , Coronavirus Infections/therapy , Coronavirus Infections/prevention & control , Pandemics/prevention & control , Treatment Outcome , Evidence-Based Medicine/methods , Medicine, Chinese Traditional/methods
17.
Ciudad Autónoma de Buenos Aires; Argentina. Ministerio de Salud de la Nación. Dirección NACIONAL De Talento Humano Y Conocimiento; 5 Mayo 2020. 7 p.
Monography in Spanish | LILACS, BINACIS, ARGMSAL, UNISALUD | ID: biblio-1096026

ABSTRACT

En el marco de la contingencia por COVID 19 que está atravesando nuestro país, es preciso tener en cuenta Consideraciones sobre la traqueotomía en pacientes con COVID -19 en ventilación mecánica


Subject(s)
Coronavirus , Betacoronavirus
18.
Lima; Perú. Ministerio de Salud; 20200500. 17 p. ilus, graf.
Monography in Spanish | LILACS, LIPECS | ID: biblio-1095749

ABSTRACT

El documento contiene las recomendaciones para el uso apropiado de mascarillas y respiradores por parte del personal de salud que participa en la atención de pacientes, en el contexto de la pandemia de COVID-19.


Subject(s)
Health Personnel , Coronavirus Infections , Personal Protective Equipment , Masks
19.
Sociol Health Illn ; 2020 May 13.
Article in English | MEDLINE | ID: mdl-32406081

ABSTRACT

With significant relevance to the Covid-19 pandemic, this paper contributes to emerging 'aerographic' research on the socio-materialities of air and breath, based on an in-depth empirical study of three hospital-based lung infection clinics treating people with cystic fibrosis. We begin by outlining the changing place of atmosphere in hospital design from the pre-antibiotic period and into the present. We then turn to the first of three aerographic themes where air becomes a matter of grasping and visualising otherwise invisible airborne infections. This includes imagining patients located within bodily spheres or 'cloud bodies', conceptually anchored in Irigaray's thoughts on the 'forgetting of the air' and Sloterdijk's immunitary 'spherology' of the body. Our second theme explores the material politics of air, air conditioning, window design and the way competing 'air regimes' come into conflict with each other at the interface of buildings, bodies and the biotic. Our final theme attends to the 'cost of air', the aero-economic problem of atmospheric scarcity within modern high-rise, deep-density healthcare architectures.

20.
Am J Transplant ; 2020 May 13.
Article in English | MEDLINE | ID: mdl-32406181

ABSTRACT

As of mid-April 2020, the coronavirus disease of 2019 (COVID-19) pandemic has affected more than 2 million people and caused 135,000 deaths worldwide. Not much is known about the effect of this disease in immunosuppressed children with renal transplantation (RT). Here we report a 13-year-old child with multiple comorbidities who acquired COVID-19 five years post-RT in the United States. Maintenance immunosuppression (IS) consisted of sirolimus and mycophenolate. There was no history of travel or exposure to sick contacts. The presenting features were fever, cough, rhinorrhea and hypoxemia. Diarrhea was the only extra pulmonary manifestation. Chest x-ray was normal. He did not require intensive care unit care or ventilation. There was a transient rise in his serum creatinine without change in urine output; dialysis was not required. Slight reduction in IS was done. He had an excellent clinical recovery within four days and was able to be discharged home. His respiratory symptoms resolved but the diarrhea persisted during a 4 week follow-up period. This report provides a brief perspective on the short-term COVID-19 clinical course in an immunosuppressed child. More reports will add valuable information on the potential variety of spectrum of the illness in this subset of children.

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