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1.
Vet Parasitol Reg Stud Reports ; 47: 100958, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38199699

ABSTRACT

Oestrosis is a nasal cavity myiasis caused by Oestrus ovis larvae from Oetrus ovis diptera flies in small ruminants. The presence of the larvae in the nasal cavity is known to cause rhinitis and sinusitis which can negatively impact the productivity of small ruminants. The aim of the present study was to estimate the prevalence of Oestrus ovis larvae infestation in sheep and goats presented for necropsy. We reviewed necropsy records of sheep and goats submitted to the Veterinary Pathology diagnostic laboratory at St. George's University from 2001 to 2017. Out of 104 goat necropsy cases, Oestrus ovis larvae were observed in 8 goats giving a prevalence of 7.7% (95% confidence interval (CI):3.38% to 14.6%). Similarly, from the 47 sheep necropsies, Oestus ovis larvae were observed in 4 sheep (8.5%) (95% CI: 2.83% to 20.46%). There was no significant difference in Oestrus ovis larvae infestation rates between sheep and goats (p = 1.000, Fisher's exact test). Oestrosis was an incidental finding in all the small ruminants examined at necropsy. This is the first report on Oestrus ovis larvae infestation in small ruminants in Grenada.


Subject(s)
Diptera , Goats , Ruminants , Sheep , Animals , Grenada , Retrospective Studies , Larva
2.
Health Sci Rep ; 7(1): e1835, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38274134

ABSTRACT

Background and Aim: Endometrial cancer (EC) is the sixth most common cancer among women worldwide. Since global studies are based on awareness of the incidence trend, mortality, geographical diversity, and level of social development and income of countries, this study was conducted to investigate the trend of uterine cancer (UC) in the world in 2019. Methods: Age-standardized rates (ASR) of incidence, deaths, prevalence, and disability-adjusted life years (DALYs) of UC, as well as targeted risk factors, were extracted from the Global Burden of Disease (GBD) online database 2019. Pearson correlation coefficient and SPSS 16 were used to calculate the correlation between risk factors and ASR of epidemiological indicators. Statistical significance was considered as p < 0.05. Results: In 2019, the age-specific incidence and death rate of UC was peaking at 60-64 and 65-69 years, respectively. The highest age-standardized incidence rate per 100,000 people for UC has been reported in the Northern Mariana Islands, high sociodemographic index (SDI) countries, World Bank High-Income category, Europe continent and among World Health Organization (WHO) regions were found in the European Region. The highest age-standardized death rate per 100,000 people for UC has been reported in Grenada, high SDI countries, the World Bank High-Income category, Europe continent, and among WHO regions found in the European Region. In 2019, the age-standardized DALYs rate was 53.54 per 100,000 inhabitants, of which 48.49 cases were related to years of life lost (YLLs) and 5.05 cases were related to years lived with disability. Conclusion: According to GBD-2019, the highest incidence, mortality, and DALY of UC are in Europe. The evidence and traces of diversity can be seen in the inequalities of UC. Race, ethnicity, economic status, level of education and awareness, co-morbidities, access, grade, and histological type of tumor are the most important causes of this inequality.

3.
Cureus ; 15(11): e48357, 2023 Nov.
Article in English | MEDLINE | ID: mdl-38060741

ABSTRACT

Background Dengue infection (DI) continues to rise in the Caribbean. Children are primarily affected by severe infection in this region. Parents thus play an essential role in identifying symptoms, seeking medical care, and preventing DI in their children. Grenada has been endemic to DI since 1956, and to date, no study has assessed the level of knowledge, attitude, and practices (KAP) among parents regarding DI. Objective To determine the level of parents' KAP and associated sociodemographic factors regarding DI in children in Grenada. Methods A quantitative cross-sectional study of 360 randomly selected parents attending postnatal and child-health clinics was conducted in Grenada. Parents completed a validated survey on demographic information and KAP regarding DI from September to December 2019. KAP scores were calculated and categorized as adequate or inadequate based on the percentage of correctly answered questions on the survey. Chi-square and logistic regression analyses were used to determine the level of KAP and associated sociodemographic factors among parents. Results Only 33.9% of parents had adequate knowledge regarding DI, which was independently associated with gender (p-value: 0.001, CI: 1.688-7.411), age (p-value: 0.001, CI: 0.037-0.443), occupation, education, and marital status. Nevertheless, most parents had a positive attitude toward DI prevention (56.4%) and practiced adequate prevention (73%) against DI. Higher education was independently associated with a positive attitude toward DI prevention (p-value: 0.013, CI: 0.190-0.825). However, no sociodemographic factors were associated with the prevention practices of DI. Conclusion This study revealed a low level of knowledge among parents, despite an adequate attitude and level of prevention against DI in Grenada. It identified specific groups, such as young, single parents of low educational status, as potential targets for educational campaigns to reduce DI-associated morbidity and mortality among Grenadian children.

4.
Cureus ; 15(11): e49427, 2023 Nov.
Article in English | MEDLINE | ID: mdl-38149146

ABSTRACT

For countries with a high prevalence of HIV such as in the Caribbean, intimate partner violence (IPV) may increase the chances for acquiring HIV infection. Using secondary data, we compared findings from studies conducted in five Caribbean countries measuring the prevalence of gender-based violence among women in Grenada, Jamaica, Guyana, Suriname, and Trinidad and Tobago. The Social-Ecological Framework was used to categorize women's dual risk for intimate partner violence and HIV. We found that younger age, lower education, childhood experiences of abuse, income dependency, controlling behaviors of partners, non-disclosure of violence, and early sexual experiences were associated with intimate partner violence. These factors also predispose women in the Caribbean to HIV infection. The Social-Ecological Framework is applicable to understanding the drivers of intimate partner violence and HIV infection at multiple levels and for the design and promotion of combined prevention interventions. Our study also demonstrated the applicability of the Social-Ecological Framework as an analytical and predictive model underscoring the need for increased coordination across multiple actors to strengthen advocacy, given the pervasiveness of harmful social norms and gender inequalities which undermine IPV and HIV control efforts.

5.
Obes Pillars ; 6: 100060, 2023 Jun.
Article in English | MEDLINE | ID: mdl-37990655

ABSTRACT

Overweight and obesity continues to be a burden to the health and well-being of Caribbean residents. The rise of childhood obesity and non-communicable diseases within the Caribbean is a major public health challenge for policymakers, educators and health professionals. These alarming rates of obesity also pose a threat to the sustainability of existing health systems particularly in small island developing states like the Caribbean. Therefore, it is crucial to evaluate existing policies and create policy solutions to address these problems and reduce the potential impact later on. This systematic review explored existing policies among countries within the Anglophone Caribbean to identify trends within the region. The literature search focused on the following themes: (i) national policies (ii) school nutrition policies and programs (iii) physical activity among youth, and (iv) food import bill and food security. An analysis was conducted on literature from national, regional and international institutions including but not limited to the World Health Organization, Ministries of Health and the Healthy Caribbean Coalition. Countries throughout the region has acknowledged the challenges with overweight and obesity in the region. Collectively decisions have been made to address food insecurity and promote healthy lifestyle behaviours through policy changes. There's still a need for Caribbean countries to work together to create effective policy solutions in collaboration with community service organizations and other stakeholders. As small island developing states grappling with the same issues, pooling resources to create effective regional policies can help to address this public health crisis.

6.
Ecol Evol ; 13(11): e10767, 2023 Nov.
Article in English | MEDLINE | ID: mdl-38020693

ABSTRACT

As an island endemic with a decreasing population, the critically endangered Grenada Dove Leptotila wellsi is threatened by accelerated loss of genetic diversity resulting from ongoing habitat fragmentation. Small, threatened populations are difficult to sample directly but advances in molecular methods mean that non-invasive samples can be used. We performed the first assessment of genetic diversity of populations of Grenada Dove by (a) assessing mtDNA genetic diversity in the only two areas of occupancy on Grenada, (b) defining the number of haplotypes present at each site and (c) evaluating evidence of isolation between sites. We used non-invasively collected samples from two locations: Mt Hartman (n = 18) and Perseverance (n = 12). DNA extraction and PCR were used to amplify 1751 bps of mtDNA from two mitochondrial markers: NADH dehydrogenase 2 (ND2) and Cytochrome b (Cyt b). Haplotype diversity (h) of 0.4, a nucleotide diversity (π) of 0.00023 and two unique haplotypes were identified within the ND2 sequences; a single haplotype was identified within the Cyt b sequences. Of the two haplotypes identified, the most common haplotype (haplotype A = 73.9%) was observed at both sites and the other (haplotype B = 26.1%) was unique to Perseverance. Our results show low mitochondrial genetic diversity and clear evidence for genetically isolated populations. The Grenada Dove needs urgent conservation action, including habitat protection and potentially augmentation of gene flow by translocation in order to increase genetic resilience and diversity with the ultimate aim of securing the long-term survival of this critically endangered species.

7.
BMC Urol ; 23(1): 166, 2023 Oct 16.
Article in English | MEDLINE | ID: mdl-37845667

ABSTRACT

INTRODUCTION: This study explores the trend of urolithiasis in various countries and categorizes the countries in terms of how their urolithiasis incidence rate has changed over time. METHODS: The incidence rate of urolithiasis in 204 countries from 1990 to 2019, extracted from the Global Burden of Disease study, has been analyzed. RESULTS: According to the results, all regions had experienced an increasing trend in urolithiasis rate, except for Eastern Europe, Central Europe, and Southeast Asia regions (decreasing rates of -71.4, -56.2, and -9.2 per 100000, respectively). Moreover, the Caribbean region had the highest increasing trend of urolithiasis rates, and Central Asia was in the next rank (increasing rate of 48.3 and 34.3 per 100,000, respectively, p-value < .05). Also, African regions revealed significant increasing trends over time (p-value < 0.05). The outstanding findings in cluster analysis showed that Afghanistan, Andorra, and Comoros had the most decreasing trend in urolithiasis rates over time (decreasing rate of -128.2 per 100000, p-value < .001). Cuba, Cyprus, Czechia, the Democratic People's Republic of Korea, Denmark, and Djibouti were in the next rank in terms of decreasing rate (decreasing rate of -92.3 per 100000, p-value < .001). In addition, urolithiasis rates in Congo, Eswatini, Gabon, and Grenada have the most increasing trend (increasing rate of 116.1 per 100000, p-value < .001). CONCLUSION: The trend of urolithiasis rates was significantly increased in most countries, and Congo, Eswatini, Gabon, and Grenada had the highest trend among others. Also, Afghanistan, Andorra, and Comoros revealed the most decreasing rates, and the trend has dropped remarkably in several other countries.


Subject(s)
Incidence , Humans , Europe/epidemiology
8.
Cureus ; 15(8): e42949, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37667693

ABSTRACT

Background Common bile duct (CBD) exploration to address choledocholithiasis is not widely practiced in the English-speaking Caribbean. This study sought to determine the frequency of laparoscopic CBD explorations in the English-speaking Caribbean and to document the stone clearance rates and short-term outcomes of this procedure. Methods We accessed records for all practicing laparoscopic surgeons in the English-speaking Caribbean who performed laparoscopic CBD explorations over a 10-year period from January 1, 2013, to June 30, 2023. The following data were extracted retrospectively from patient records: demographic details, operating time, stone clearance rates, retained stone rates, conversions, and complications. All data were analyzed with SPSS version 20 (IBM Corp., Armonk, NY). Results Over the 10-year study period, 35 patients underwent laparoscopic cholecystectomy and synchronous CBD exploration in Barbados, Cayman Islands, Guyana, Grenada, St Lucia, and Trinidad & Tobago. The procedure was performed at low volumes of only 0.7 procedures per surgical team per annum. The conversion rate to open CBD exploration was 13% and when laparoscopic CBD exploration was completed, it resulted in 96.3% stone clearance, 3.7% retained stones, mean hospitalization of two days, 9.7% minor morbidity, and no mortality. Conclusion Laparoscopic CBD exploration is feasible in the resource-poor Caribbean setting, and it yields good results, with 96.3% stone clearance rates, 9.7% minor morbidity, and no mortality. These results are better than those reported in Caribbean literature for stone extraction with endoscopic retrograde cholangiopancreaticography (ERCP).

9.
Front Public Health ; 11: 1127687, 2023.
Article in English | MEDLINE | ID: mdl-37744480

ABSTRACT

Childrearing practices in the Caribbean and other postcolonial states have long been associated with corporal punishment and are influenced by expectations of children for respectfulness and obedience. Evidence across settings shows that physical punishment of young children is both ineffective and detrimental. Saving Brains Grenada (SBG) implemented a pilot study of an intervention based on the Conscious Discipline curriculum that aimed to build adult caregivers' skills around non-violent child discipline. We hypothesized that attitudes towards corporal punishment would shift to be negative as adults learned more positive discipline methods, and that child neurodevelopment would correspondingly improve. This report reviews the impact of monitoring and evaluation on the design and implementation of the intervention. Study 1 presents findings from the pilot study. Despite positive gains in neurodevelopmental outcomes among children in the intervention compared to controls, attitudes towards corporal punishment and reported use of it did not change. Additionally, several internal conflicts in the measures used to assess corporal punishment behaviors and attitudes were identified. Study 2 is a response to learning from Study 1 and highlights the importance for monitoring and evaluation to be data-informed, adaptive, and culturally appropriate. In Study 2, the SBG research team conducted cognitive interviews and group discussions with stakeholders to assess the content and comprehensibility of the Attitudes Towards Corporal Punishment Scale (ACP). This yielded insights into the measurement of attitudes towards corporal punishment and related parenting behavior, and prompted several revisions to the ACP. To accurately evaluate the intervention's theory of change and its goal to reduce violence against children, reliable and appropriate measures of attitudes towards corporal punishment and punishment behaviors are needed. Together, these two studies emphasize the value of continuous monitoring, evaluation, and learning in the implementation, adaptation, evaluation, and scaling of SBG and similar early childhood development interventions.


Subject(s)
Brain , Punishment , Adult , Child , Child, Preschool , Humans , Grenada , Pilot Projects , Attitude
10.
Environ Sci Pollut Res Int ; 30(50): 109585-109605, 2023 Oct.
Article in English | MEDLINE | ID: mdl-37776424

ABSTRACT

This article deals with the analysis of [Formula: see text] emissions in Latin America by using a long memory process based on fractional integration. Using data of [Formula: see text] emission and [Formula: see text] emissions per capita, for 32 Latin American and Caribbean countries, the results show significant differences according to the variable examined, the model used, and the country under examination. In particular, for the [Formula: see text] emissions, mean reversion is found in Belize and also under some circumstances in Antigua and Barbuda, Colombia, Dominica, Dominican Republic, Ecuador, Grenada, Honduras, Nicaragua, Panama, Peru, and Uruguay. Thus, shocks in these series have a transitory effect. With respect to the time trends, only for some Caribbean countries, namely, Antigua and Barbuda, Aruba, Bahamas, Cuba, and Jamaica, the trend is insignificant; on the other hand, large countries like Brazil, Mexico, and Argentina display the highest time trend coefficients; for the [Formula: see text] emissions per capita, there are eleven countries where mean reversion is detected, and there are ten that share a lack of significance for the trend. The most significant trends now take place in Trinidad and Tobago, British Virgin Islands, Barbados, and Guyana. Policy implications of the results obtained are reported at the end of the paper.


Subject(s)
Carbon Dioxide , Latin America , Time Factors , Mexico , Argentina , Caribbean Region
11.
Washington, D.C.; PAHO; 2023-08-18.
in English, Spanish | PAHO-IRIS | ID: phr-57970

ABSTRACT

[WEEKLY SUMMARY]. North America: Influenza activity has remained at low levels. Over the past 4 epidemiological weeks (EW), the predominant influenza viruses have been influenza A(H1N1)pdm09, with concurrent circulation of influenza B/Victoria. Respiratory syncytial virus (RSV) activity has stayed at low levels. The activity of SARS-CoV-2 has shown an increase over the last 4 EWs and continues to circulate at moderate levels. Cases of influenza-like illness (ILI) and severe acute respiratory infection (SARI) have seen a slight increase, with the majority of these cases associated with SARS-CoV-2 and to a lesser extent with influenza. In Mexico, epidemic levels of influenza circulation have been detected, which are decreasing. Caribbean: Influenza activity continues to show a decreasing trend over the past 4 EWs, with a predominance of influenza B/Victoria and, to a lesser extent, circulation of influenza A, mainly A(H1N1)pdm09. RSV activity has remained low. The activity of SARS-CoV-2 has shown an increasing trend over the last three EWs, with intermediate levels of circulation, especially in Barbados, Grenada, Guyana, Jamaica, and Saint Lucia. ILI and SARI cases have displayed a decreasing trend in the past 4 EWs. Central America: After reaching a peak in previous weeks, influenza activity has continued to decline over the last 4 EWs. During this period, the predominant influenza viruses have been influenza B/Victoria with concurrent circulation of influenza A, mainly A(H1N1)pdm09, and to a lesser extent, influenza A(H3N2). RSV activity has increased in the last 4 EWs, reaching intermediate to high levels of circulation. The activity of SARS-CoV-2 has remained low. ILI activity has remained low, with the majority of cases associated with influenza. SARI activity is currently declining, with the majority of cases associated with RSV. In Costa Rica, extraordinary levels of influenza positivity are detected with concurrent circulation of SARS-CoV-2. ILI and SARI levels remain low, with the majority of cases associated with influenza and, to a lesser extent, with SARS-CoV-2. In El Salvador, influenza activity is decreasing, with epidemic levels in reported SARI cases. Additionally, there has been an increase in RSV positivity levels with elevated activity. In Honduras, after reaching elevated levels in the percentages of influenza positivity, the last 4 EWs have seen a decline to levels below the epidemic threshold. ILI and SARI cases are currently decreasing, with almost all positive cases related to influenza. In Guatemala, RSV activity continues to rise with moderate to high levels, and ILI cases are mostly positive for influenza, while SARI cases are positive for RSV. In Nicaragua and Panama, after achieving moderate activity levels in previous EWs, influenza positivity in both countries is currently at epidemic levels. Andean region: Influenza activity remains stable at low levels. Over the last 4 EWs, the predominant influenza viruses have been influenza A, predominantly A(H1N1)pdm09, with lesser circulation of influenza B/Victoria. RSV activity remains at low levels. SARSCoV- 2 has shown a decline over the last 4 EWs, circulating at low levels, although circulation remains elevated in Bolivia. SARI activity continues to decline, with most cases associated with influenza and, to a lesser extent, RSV and SARS-CoV-2. ILI activity has shown a decreasing trend, with most cases associated with influenza.. Brazil and Southern Cone: Influenza activity has decreased to low levels of circulation. Over the past 4 EWs, the predominant viruses have been primarily influenza A(H1N1)pdm09, with simultaneous circulation of influenza B/Victoria. RSV activity has declined in the last 4 EWs, reaching low levels of circulation. SARS-CoV-2 activity has remained low, albeit with a slight increase. Both SARI and ILI activities have continued to decline over the past 4 EWs. Argentina continues to experience epidemic levels of influenza activity, with the majority of detected cases being positive for influenza A(H1N1)pdm09 and ILI and SARI levels below the epidemic threshold. In Brazil, influenza and RSV activity remains low, while SARS-CoV-2 has shown a slight increase in the last EW. In Chile, ILI activity has increased, remaining at moderate levels, with the majority of positive cases related to influenza. In Paraguay, SARI activity remains high, with RSV being the primary cause among positive cases, followed by SARS-CoV-2. In Uruguay, SARI activity remains at epidemic levels, with the majority of cases associated with RSV.


[RESUMEN SEMANAL]. Norteamérica: La actividad de influenza ha permanecido en niveles bajos. Durante las últimas 4 semanas epidemiológicas (SE) los virus influenza predominantes han sido influenza A(H1N1)pdm09, con circulación concurrente de influenza B/Victoria. La actividad del virus sincitial respiratorio (VSR) se ha mantenido en niveles bajos. La actividad del SARS-CoV-2 ha presentado un incremento en las últimas 4 SE y continúa circulando en niveles moderados. Los casos de enfermedad tipo influenza (ETI) e infección respiratoria aguda grave (IRAG) han presentado un ligero incremento, siendo la mayor parte de estos asociados a SARS-CoV-2 y en menor medida a influenza. En México se han detectado niveles epidémicos de circulación de influenza que continúa en descenso. Caribe: La actividad de la influenza continúa mostrando una tendencia decreciente en las últimas 4 SE, con predominio de influenza B/Victoria, y en menor medida circulación de influenza A, principalmente A(H1N1)pdm09. La actividad del VSR ha permanecido baja. La actividad del SARS-CoV-2 ha mostrado una tendencia creciente en las últimas tres SE con niveles intermedios de circulación, especialmente en Barbados, Grenada, Guyana, Jamaica y Saint Lucia. Los casos de ETI e IRAG han mostrado una tendencia decreciente en las últimas 4 SE. Centroamérica: Tras alcanzar un pico en semanas previas, la actividad de influenza ha continuado en descenso durante las 4 últimas SE. Durante este periodo, los virus predominantes han sido influenza B/Victoria con circulación concurrente de influenza A, principalmente A(H1N1)pdm09, y en menor medida de influenza A(H3N2). La actividad del VSR ha aumentado en las últimas 4 SE, situándose en niveles intermedios-altos de circulación. La actividad de SARS-CoV-2 se ha mantenido baja. La actividad de ETI se ha mantenido baja con la mayoría de los casos asociados a influenza. La actividad de IRAG se encuentra actualmente en descenso, con la mayoría de los casos asociados al VSR. En Costa Rica se mantienen niveles de positividad de influenza extraordinarios, coincidentes con la circulación de SARS-CoV-2. Los niveles de ETI e IRAG continúan siendo bajos con la mayoría de los casos asociados a influenza y en menor medida a SARS-CoV-2. En El Salvador la actividad de influenza se mantiene en descenso, con niveles epidémicos en los casos IRAG notificados. Adicionalmente, se ha observado un incremento en los niveles de positividad de VSR con una actividad elevada. En Honduras tras alcanzar niveles elevados en los porcentajes de positividad de influenza, en las 4 últimas SE se ha observado un descenso hasta niveles por debajo del umbral epidémico. Los casos de ETI e IRAG actualmente se encuentran en descenso siendo casi la totalidad de los positivos relacionados con influenza. En Guatemala la actividad del VSR continúa en ascenso con niveles moderados-altos, y los casos ETI positivos en su mayoría son debidos a influenza y los casos IRAG positivos para VSR. En Nicaragua y Panamá tras los niveles de actividad moderados


Subject(s)
Influenza, Human , SARS-CoV-2 , COVID-19 , Betacoronavirus , International Health Regulations , Americas , Caribbean Region , Influenza, Human , International Health Regulations , Americas , Caribbean Region
12.
Perfil de carga de enfermedad por diabetes 2023OPS/NMH/NV/23-0033.
Monography in Spanish | PAHO-IRIS | ID: phr-57841

ABSTRACT

El propósito fundamental de esta serie de perfiles nacionales de la carga de enfermedad por diabetes y de enfermedad renal crónica debida a diabetes es apoyar a los países de la Región de las Américas en el seguimiento de las estrategias puestas en marcha para enfrentar la diabetes. Esta primera versión de los perfiles, que abarca el período comprendido entre el 2000 y el 2019, muestra la tendencia de la mortalidad, los años de vida perdidos por muerte prematura, los años vividos con discapacidad y los años de vida ajustados por discapacidad de ambas enfermedad. Se han elaborado con los últimos datos disponibles de las estimaciones mundiales de salud de la Organización Mundial de la Salud y tiene como objetivo convertirse en una herramienta útil para llevar a cabo el monitoreo de las estrategias conexas.


Subject(s)
Diabetes Mellitus , Kidney Diseases , Sanitary Profiles , Grenada
13.
Zootaxa ; 5271(2): 253-270, 2023 Apr 26.
Article in English | MEDLINE | ID: mdl-37518129

ABSTRACT

During a survey in Trinidad and Grenada for putative vectors of palm lethal decline phytoplasmas, three species of planthopper in the genus Melanoliarus (Hemiptera, Cixiidae) were collected. Melanoliarus maidis was collected from coconut palms in Grenada, M. kindli was collected from grasses in a coconut plot in Trinidad and a new species of Melanoliarus was collected from coconut palms in Trinidad. Herein the novel taxon is described with supplementary molecular data for the cytochrome c oxidase subunit I (COI) gene, 18S rRNA gene, and histone 3 (H3) gene to support placement in the genus Melanoliarus in the strict sense.


Subject(s)
Arecaceae , Hemiptera , Animals , Cocos , Hemiptera/genetics , Trinidad and Tobago , Surveys and Questionnaires
14.
Mar Pollut Bull ; 194(Pt A): 115292, 2023 Sep.
Article in English | MEDLINE | ID: mdl-37473611

ABSTRACT

Managing abandoned, lost and otherwise discarded fishing gear (ALDFG) is a critical challenge that can be aided by the establishment of strong provisions for the marking of gear. This study presents an analysis of implementation of the VGMFG in Eastern Caribbean states. It provides a socio-legal review of this issues and an analysis of compliance and implementation gaps. Empirical data was gathered through interviews with 56 fishers in 2 jurisdictions as well as 6 national and regional fisheries management experts. Antigua and Barbuda's Fisheries Regulations provided the strongest support to implementation of the VGMFG, while neither Dominica nor Grenada had weak regulatory support for gear marking. Both fishers and fisheries managers in the region confirmed compliance and implementation gaps in the establishment of gear marking schemes, while regional fisheries experts highlighted the limited human, financial and infrastructural capacity of departments to effectively implement such schemes along with other ALDFG management measures.


Subject(s)
Fisheries , Hunting , Humans , Caribbean Region
15.
Viruses ; 15(6)2023 05 30.
Article in English | MEDLINE | ID: mdl-37376590

ABSTRACT

Maternal infection with Zika virus (ZIKV) is associated with a distinct pattern of birth defects, known as congenital Zika syndrome (CZS). In ZIKV-exposed children without CZS, it is often unclear whether they were protected from in utero infection and neurotropism. Early neurodevelopmental assessment is essential for detecting neurodevelopmental delays (NDDs) and prioritizing at-risk children for early intervention. We compared neurodevelopmental outcomes between ZIKV-exposed and unexposed children at 1, 3 and 4 years to assess exposure-associated NDD risk. A total of 384 mother-child dyads were enrolled during a period of active ZIKV transmission (2016-2017) in Grenada, West Indies. Exposure status was based on laboratory assessment of prenatal and postnatal maternal serum. Neurodevelopment was assessed using the Oxford Neurodevelopment Assessment, the NEPSY® Second Edition and Cardiff Vision Tests, at 12 (n = 66), 36 (n = 58) and 48 (n = 59) months, respectively. There were no differences in NDD rates or vision scores between ZIKV-exposed and unexposed children. Rates of microcephaly at birth (0.88% vs. 0.83%, p = 0.81), and childhood stunting and wasting did not differ between groups. Our results show that Grenadian ZIKV-exposed children, the majority of whom were without microcephaly, had similar neurodevelopmental outcomes to unexposed controls up to at least an age of 4 years.


Subject(s)
Microcephaly , Nervous System Malformations , Pregnancy Complications, Infectious , Zika Virus Infection , Zika Virus , Pregnancy , Infant, Newborn , Female , Humans , Child, Preschool , Infant , Child , Zika Virus Infection/complications , Zika Virus Infection/epidemiology , Zika Virus Infection/diagnosis , Microcephaly/epidemiology , Microcephaly/etiology , Microcephaly/diagnosis , Grenada/epidemiology , Cognition
16.
Parasitology ; 150(8): 754-759, 2023 07.
Article in English | MEDLINE | ID: mdl-37184089

ABSTRACT

Canine soil-transmitted helminths (STHs) cause important zoonoses in the tropics, with varying degrees of intensity of infection in humans and dogs. This study aimed to investigate the prevalence and associated risk factors for STHs in community dogs residing in Grenada, West Indies. In May 2021, 232 canine fecal samples were examined for zoonotic helminths by microscopy (following flotation), and genomic DNA from a subset of 211 of these samples were subjected to multiplex qPCR for the detection and specific identification of hookworms, Toxocara spp. and Strongyloides. Microscopic examination revealed that 46.5% (108/232, 95% CI 40­52.9), 9% (21/232, 95% CI 5.35­12.7) and 5.2% (12/232, 95% CI 2.3­8) of the samples contained eggs of Ancylostoma spp., Toxocara spp. and Trichuris vulpis, respectively. Multiplex qPCR revealed that, 42.2% (89/211, 95% CI 35.5­48.8) were positive for at least 1 zoonotic parasite. Of these, 40.8% (86/211, 95% CI 34.1­47.3) of samples tested positive for Ancylostoma spp., 36% (76/211, 95% CI 29.5­42.9) were positive for A. caninum, 13.3% (28/211, 95% CI 9­18.6) for A. ceylanicum, 5.7% for T. canis (12/211, 95% CI 2.97­8.81) and 1% (2/211, 95% CI 0­2.26) for Strongyloides spp. (identified as S. stercoralis and S. papillosus by conventional PCR-based Sanger sequencing). Using a multiple logistic regression model, a low body score and free-roaming behaviour were significant predictors of test-positivity for these parasitic nematodes in dogs (P < 0.05). Further studies of zoonotic STHs in humans should help elucidate the public health relevance of these parasites in Grenada.


Subject(s)
Dog Diseases , Helminths , Animals , Dogs , Humans , Ancylostoma , Dog Diseases/epidemiology , Dog Diseases/parasitology , Feces/parasitology , Grenada/epidemiology , Helminths/classification , Helminths/genetics , Prevalence , Risk Factors , Toxocara , Zoonoses/epidemiology
17.
Am J Trop Med Hyg ; 109(1): 123-125, 2023 07 05.
Article in English | MEDLINE | ID: mdl-37253436

ABSTRACT

Neonates are vulnerable to vector-borne diseases given the potential for mother-to-child congenital transmission. To determine factors associated with chikungunya virus (CHIKV) infection among pregnant women in Grenada, West Indies, a retrospective cohort study enrolled women who were pregnant during the 2014 CHIKV epidemic. In all, 520/688 women (75.5%) were CHIKV IgG positive. Low incomes, use of pit latrines, lack of home window screens, and subjective reporting of frequent mosquito bites were associated with increased risk of CHIKV infection in bivariate analyses. In the multivariate modified Poisson regression model, low income (adjusted relative risk [aRR]: 1.05 [95% CI: 1.01-1.10]) and frequent mosquito bites (aRR: 1.05 [95% CI: 1.01-1.10]) were linked to increased infection risk. In Grenada, markers of low socioeconomic status are associated with CHIKV infection among pregnant women. Given that Grenada will continue to face vector-borne outbreaks, interventions dedicated to improving living conditions of the most disadvantaged will help reduce the incidence of arboviral infections.


Subject(s)
Chikungunya Fever , Insect Bites and Stings , Infant, Newborn , Female , Humans , Pregnancy , Grenada/epidemiology , Pregnant Women , Insect Bites and Stings/complications , Retrospective Studies , Infectious Disease Transmission, Vertical
18.
Cureus ; 15(3): e36222, 2023 Mar.
Article in English | MEDLINE | ID: mdl-37065326

ABSTRACT

Objective This article explores the value of hosting a grassroots neuroscience workshop that facilitates near-peer engagement between year-one medical students and local Brain Bee finalists (high school students). Near-peer mentoring is a formal relationship in which more academically advanced students guide immediate junior students. We hypothesized that similar activities have teaching, learning, and psychosocial benefits for all and can be easily replicated. Activity The Grenada National Brain Bee Challenge was launched in 2009 as a competition for high school students. Annually, there are at least 100 high school students registering to participate in the national challenge. In 2018, a grassroots neuroscience symposium, a local initiative, was created to prepare high school students who participated in the preliminary rounds for the final local and International Brain Bee competition. Traditionally, it is hosted annually by faculty at St. George's University School of Medicine (SOM). However, in 2022, the symposium was hosted by medical students. The symposium is designed as an eight-hour tutorial one-day session. The students rotate between facilitators as small group teams during each teaching hour. There are icebreakers, content presentations, and neuroanatomy skills stations. The medical students demonstrate expertise in neuroscience content and other aspects of professional competence. The activity was also designed to offer students of diversified backgrounds the opportunity to affect their educational pathways through role modeling, mirroring, and mentorship. Was this change beneficial to both sets of students (medical and high school)? Results and discussion We aim to determine the value of the near-peer relationship between the local 2022 Brain Bee finalists (high school students) (n=28) and university (medical) students (n=11). Participants were surveyed about their experience. Data were de-identified and grouped according to common themes. A thematic analysis was conducted on the data retrieved from the literature review. Data suggest that both high school and university (medical) students report benefits after participating in near-peer engagement at a grassroots neuroscience symposium. In this teaching model, the medical students are the more experienced instructors and transfer their knowledge and skills about the field to the high school students. The medical students have an opportunity to consolidate their personal learning and give back to the Grenadian community. While informal teaching occurs often, this type of near-peer engagement with students from the community helps medical students develop both personal and professional skills such as confidence, knowledge, and respect. This grassroots initiative is easily replicated in a medical curriculum. The major benefits experienced by the high school student participants (of various socioeconomic backgrounds) were access to educational resources. The symposium requires active engagement, fosters a sense of belonging, and promotes interest in pursuing careers in health, research, academia, and Science, Technology, Engineering, and Mathematics (STEM). Conclusion Participating high school students of various genders and socioeconomic backgrounds gained equal access to educational resources and may select careers in health-related sciences. Participating medical students developed knowledge and teaching skills and engaged in a service-learning opportunity.

19.
Rev Panam Salud Publica ; 47: e68, 2023.
Article in Portuguese | MEDLINE | ID: mdl-37066130

ABSTRACT

Objective: To identify the temporal trend in mortality and years of life lost to death or disability (DALY) due to motorcycle accidents in males from Latin America and the Caribbean from 2010 to 2019, using estimates produced by the Global Burden of Disease (GBD) study. Method: In this ecological study, the time series was analyzed using a piecewise linear regression model (joinpoint) to estimate and test the annual percent change and the average annual percent change with a 95% confidence interval. Results: The super-region defined by GBD 2019 as Latin America and the Caribbean ranked first globally in mortality and DALY for male motorcyclists aged 15-49 in 2019. Rates increased significantly from 2010 to 2013, with a significant reduction in both after this period. During the analyzed decade, the Tropical Latin America sub-region (Brazil and Paraguay) had the highest mortality and DALY rates in the population of interest; nevertheless, this was the only sub-region achieving a significant reduction in these rates. The Caribbean sub-region (Bermuda, Dominica, Suriname, Guyana, Belize, Bahamas, Puerto Rico, Saint Lucia, Dominican Republic, Haiti, Saint Kitts and Nevis, U.S. Virgin Islands, Grenada, Trinidad and Tobago, Barbados, Saint Vincent and the Grenadines, Antigua and Barbuda, Cuba e Jamaica) showed a significant increase in both rates over the same period, while Andean Latin America (Ecuador, Bolivia and Peru) and Central Latin America (Colombia, Costa Rica, El Salvador, Guatemala, Mexico, Nicaragua, Panama, Honduras, and Venezuela) remained stable. Conclusions: The data underscore the importance of developing surveillance actions aimed at preventing motorcycle accidents, since the observed declining rates are still insufficient to address the morbidity and mortality associated with road accidents as a public health problem.


Objetivo: Determinar la tendencia temporal de la mortalidad y los años de vida perdidos por muerte o ajustados por discapacidad (AVAD) de hombres por accidentes de motocicleta en América Latina y el Caribe en el período 2010-2019, a partir de las estimaciones del estudio de la carga mundial de enfermedades (CME). Métodos: En este estudio ecológico se analizaron las series temporales mediante el modelo de regresión lineal segmentada (joinpoint), con cálculo y comprobación del cambio porcentual anual y del cambio porcentual anual promedio, con un intervalo de confianza del 95%. Resultados: La región de América Latina y el Caribe definida por el estudio de la CME ocupó el primer lugar a nivel mundial en mortalidad y AVAD de motociclistas varones de 15 a 49 años en el 2019. Las tasas tuvieron un notable aumento del 2010 al 2013, y ambas registraron una reducción importante después de ese período. En la década analizada, la subregión de América Latina Tropical (Brasil y Paraguay) presentó las mayores tasas de mortalidad y de AVAD en la población de estudio, pero fue la única con una reducción importante de las mismas. La subregión del Caribe (Antigua y Barbuda, Bahamas, Barbados, Belice, Bermudas, Cuba, Dominica, Granada, Guyana, Haití, Islas Vírgenes de Estados Unidos, Jamaica, Puerto Rico, República Dominicana, Saint Kits y Nevis, San Vicente y las Granadinas, Santa Lucía, Suriname, y Trinidad y Tabago) mostró un aumento importante de ambas tasas, mientras que América Latina Andina (Bolivia, Ecuador y Perú) y América Latina Central (Colombia, Costa Rica, El Salvador, Guatemala, Honduras, México, Nicaragua, Panamá y Venezuela) se mantuvieron estables. Conclusiones: Los datos refuerzan la importancia de las actividades de vigilancia destinadas a prevenir los accidentes de motocicleta, puesto que la reducción observada de las tasas aún es insuficiente para abordar la morbimortalidad por accidentes de tráfico como problema de salud pública.

20.
Article in Portuguese | PAHO-IRIS | ID: phr-57369

ABSTRACT

[RESUMO]. Objetivo. Identificar a tendência temporal da mortalidade e dos anos de vida perdidos por morte ou incapaci- dade (DALY) de homens por acidente motociclístico na América Latina e Caribe no período de 2010 a 2019, utilizando estimativas do estudo Global Burden of Disease (GBD). Métodos. Este estudo ecológico analisou a série temporal pelo modelo de regressão linear segmentada (joinpoint), estimando-se e testando-se a variação percentual anual e a variação percentual anual média, com intervalo de confiança de 95%. Resultados. A grande região da América Latina e Caribe definida pelo GBD ocupou o primeiro lugar global em mortalidade e DALY de motociclistas homens de 15 a 49 anos em 2019. As taxas aumentaram significa- tivamente de 2010 a 2013, havendo redução significativa de ambas após esse período. Durante a década analisada, a sub-região da América Latina Tropical (Brasil e Paraguai) apresentou as maiores taxas de mortali- dade e DALY na população em estudo, porém foi a única com redução significativa das mesmas; a sub-região do Caribe (Bermudas, Dominica, Suriname, Guiana, Belize, Bahamas, Porto Rico, Santa Lúcia, República Dominicana, Haiti, São Cristóvão e Névis, Ilhas Virgens/EUA, Granada, Trinidad e Tobago, Barbados, São Vicente e Granadinas, Antígua e Barbuda, Cuba e Jamaica) apresentou aumento significativo de ambas as taxas, enquanto América Latina Andina (Equador, Bolívia e Peru) e América Latina Central (Colômbia, Costa Rica, El Salvador, Guatemala, México, Nicarágua, Panamá, Honduras e Venezuela) permaneceram estáveis. Conclusões. Os dados reforçam a importância das ações de vigilância destinadas à prevenção de acidentes motociclísticos, uma vez que os resultados de queda nas taxas ainda são insuficientes frente à morbimortali- dade no trânsito como problema de saúde pública.


[ABSTRACT]. Objective. To identify the temporal trend in mortality and years of life lost to death or disability (DALY) due to motorcycle accidents in males from Latin America and the Caribbean from 2010 to 2019, using estimates produced by the Global Burden of Disease (GBD) study. Method. In this ecological study, the time series was analyzed using a piecewise linear regression model (joinpoint) to estimate and test the annual percent change and the average annual percent change with a 95% confidence interval. Results. The super-region defined by GBD 2019 as Latin America and the Caribbean ranked first globally in mortality and DALY for male motorcyclists aged 15-49 in 2019. Rates increased significantly from 2010 to 2013, with a significant reduction in both after this period. During the analyzed decade, the Tropical Latin America sub-region (Brazil and Paraguay) had the highest mortality and DALY rates in the population of interest; never- theless, this was the only sub-region achieving a significant reduction in these rates. The Caribbean sub-region (Bermuda, Dominica, Suriname, Guyana, Belize, Bahamas, Puerto Rico, Saint Lucia, Dominican Republic, Haiti, Saint Kitts and Nevis, U.S. Virgin Islands, Grenada, Trinidad and Tobago, Barbados, Saint Vincent and the Grenadines, Antigua and Barbuda, Cuba e Jamaica) showed a significant increase in both rates over the same period, while Andean Latin America (Ecuador, Bolivia and Peru) and Central Latin America (Colombia, Costa Rica, El Salvador, Guatemala, Mexico, Nicaragua, Panama, Honduras, and Venezuela) remained stable. Conclusions. The data underscore the importance of developing surveillance actions aimed at preventing motorcycle accidents, since the observed declining rates are still insufficient to address the morbidity and mortality associated with road accidents as a public health problem.


[RESUMEN]. Objetivo. Determinar la tendencia temporal de la mortalidad y los años de vida perdidos por muerte o ajusta- dos por discapacidad (AVAD) de hombres por accidentes de motocicleta en América Latina y el Caribe en el período 2010-2019, a partir de las estimaciones del estudio de la carga mundial de enfermedades (CME). Métodos. En este estudio ecológico se analizaron las series temporales mediante el modelo de regresión lineal segmentada (joinpoint), con cálculo y comprobación del cambio porcentual anual y del cambio porcentual anual promedio, con un intervalo de confianza del 95%. Resultados. La región de América Latina y el Caribe definida por el estudio de la CME ocupó el primer lugar a nivel mundial en mortalidad y AVAD de motociclistas varones de 15 a 49 años en el 2019. Las tasas tuvieron un notable aumento del 2010 al 2013, y ambas registraron una reducción importante después de ese período. En la década analizada, la subregión de América Latina Tropical (Brasil y Paraguay) presentó las mayores tasas de mortalidad y de AVAD en la población de estudio, pero fue la única con una reducción impor- tante de las mismas. La subregión del Caribe (Antigua y Barbuda, Bahamas, Barbados, Belice, Bermudas, Cuba, Dominica, Granada, Guyana, Haití, Islas Vírgenes de Estados Unidos, Jamaica, Puerto Rico, República Dominicana, Saint Kits y Nevis, San Vicente y las Granadinas, Santa Lucía, Suriname, y Trinidad y Tabago) mostró un aumento importante de ambas tasas, mientras que América Latina Andina (Bolivia, Ecuador y Perú) y América Latina Central (Colombia, Costa Rica, El Salvador, Guatemala, Honduras, México, Nicaragua, Panamá y Venezuela) se mantuvieron estables. Conclusiones. Los datos refuerzan la importancia de las actividades de vigilancia destinadas a prevenir los accidentes de motocicleta, puesto que la reducción observada de las tasas aún es insuficiente para abordar la morbimortalidad por accidentes de tráfico como problema de salud pública.


Subject(s)
Accidents, Traffic , Motorcycles , Mortality , Disability-Adjusted Life Years , Road Safety , Accidents, Traffic , Motorcycles , Mortality , Disability-Adjusted Life Years , Road Safety
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