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1.
Dental Press J Orthod ; 27(5): e2220325, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36350943

RESUMO

INTRODUCTION: Many patients wearing orthodontic appliances request alterations in the shade of their teeth during orthodontic treatment. OBJECTIVE: This study aimed to evaluate the efficacy of different products for bleaching and whitening under orthodontic brackets. METHODS: Seventy bovine incisors were randomly divided into five groups (n = 14): C) non-whitening toothpaste (control); WTsi) hydrated silica whitening toothpaste; WThp) 2% hydrogen peroxide whitening toothpaste; OB) in-office bleaching; and HB) at-home bleaching. Two buccal surface areas were evaluated using the Easyshade spectrophotometer: under the metal bracket (experimental) and around the bracket (control). The paired t-test, ANOVA, and Tukey tests were applied for statistical analysis. RESULTS: Intragroup comparisons showed that in groups C, WThp and HB, there were statistically significant differences in the enamel color changes (ΔEab) between under and around the bracket areas (C - under bracket = 7.97 ± 2.35, around bracket = 2.86 ± 0.81, p< 0.01; WThp - under bracket = 4.69 ± 2.98, around bracket = 2.05 ± 1.41, p< 0.01; HB - under bracket = 7.41 ± 2.89, around bracket: 9.86 ± 3.32, p= 0.02). Groups WTsi, OB and HB presented similar perception of tooth whiteness (ΔWID) between the tested areas. Intergroup comparisons demonstrated that under the bracket area, the color change (ΔEab) was similar for all groups, except WThp (C = 7.97 ± 2.35; WTsi = 8.54 ± 3.63; WThp = 4.69 ± 2.98; OB = 9.31 ± 4.32; HB = 7.41 ± 2.89; p< 0.01). CONCLUSIONS: The dental color changes were effective for the products tested in groups WTsi, OB and HB in the presence of metallic orthodontic brackets.


Assuntos
Braquetes Ortodônticos , Clareadores Dentários , Clareamento Dental , Animais , Bovinos , Humanos , Cor , Esmalte Dentário , Peróxido de Hidrogênio , Clareadores Dentários/uso terapêutico , Cremes Dentais
2.
PLoS One ; 17(11): e0277346, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36395262

RESUMO

OBJECTIVE: This clinical trial evaluated the effect of 1.5% potassium oxalate (PO) in controlling sensitivity and color change after at-home tooth whitening. It also evaluated the influence of PO on health-related quality of life (HRQoL) and the degree of patient satisfaction after bleaching treatment. MATERIALS AND METHODS: Fifty volunteers were randomized into two groups (n = 25): At-home bleaching gel with 22% carbamide peroxide for 45 min + placebo gel (GP) or 1.5% PO (GPO) for 10 min. The intensity of tooth sensitivity was assessed daily through the visual analog scale. The color analysis was performed three times: baseline, 21 days, and 1 month after the last application of the whitening gel. The impact of the oral condition on the patient's quality of life (OIDP) was used to measure the impact caused by the whitening treatment in relation to the individuals' ability to carry out their daily activities and its influence on HRQOL. RESULTS: No difference in tooth sensitivity was observed (p > 0.05). In addition, there was no difference in color change between groups (p > 0.05). However, there was an intragroup statistical difference throughout the evaluation period (p <0.05). The OIDP analysis showed a statistical difference between the groups (p > 0.05) and there was no difference between the groups regarding the degree of satisfaction with the bleaching (p > 0.05). CONCLUSIONS: The 1.5% PO was effective in preventing sensitivity and did not interfere with tooth whitening. Desensitizing therapy had a positive impact on quality of life and patient satisfaction.


Assuntos
Sensibilidade da Dentina , Clareadores Dentários , Clareamento Dental , Humanos , Clareamento Dental/efeitos adversos , Qualidade de Vida , Sensibilidade da Dentina/tratamento farmacológico , Clareadores Dentários/uso terapêutico , Ácido Oxálico , Peróxido de Hidrogênio
4.
Indian J Dent Res ; 33(2): 188-192, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36254958

RESUMO

Aim: To investigate the effects of bleaching with 35% hydrogen peroxide on the structure of tooth enamel and the role of two remineralizing agents for their potential to remineralize any damaged regions of enamel. Materials and Methods: Freshly extracted 32 mature permanent central incisors were selected and sectioned at the level of the cemento-enamel junction. The teeth were divided into four groups consisting of eight teeth each: No bleaching (control) [Group 1], bleaching with 35% hydrogen peroxide [Group 2], bleaching with 35% hydrogen peroxide followed by application of casein phosphopeptide amorphous calcium phosphate fluoride paste [Group 3], and bleaching with 35% hydrogen peroxide followed by application of xylitol-coated calcium phosphate fluoride varnish [Group 4]. The enamel surfaces were analyzed under the scanning electron microscope and quantitative energy dispersive X-ray analysis. Results: Results were statistically analyzed by one-way analysis of variance and Tukey's posthoc test. Group 2 revealed changes in enamel surface morphology and a statistically significant decrease in mineral content. Groups 3 and 4 showed statistically significant remineralization potential. Intergroup comparison showed that samples in Group 4 had a higher mineral content compared to Group 3. Conclusions: The application of the tested remineralizing agents following bleaching was effective in repairing the enamel surface morphology with higher efficacy for the fluoride varnish product. Since bleaching regimes with high concentrations of hydrogen peroxide adversely affect the enamel surface, these findings can translate to clinical practice to reduce the long-term damaging effects of tooth bleaching.


Assuntos
Clareadores Dentários , Clareamento Dental , Fosfatos de Cálcio/farmacologia , Caseínas/farmacologia , Esmalte Dentário , Fluoretos/farmacologia , Fluoretos Tópicos/farmacologia , Peróxido de Hidrogênio/farmacologia , Minerais , Fosfopeptídeos/farmacologia , Clareamento Dental/métodos , Clareadores Dentários/farmacologia , Remineralização Dentária/métodos , Xilitol/farmacologia
5.
Eur J Med Res ; 27(1): 194, 2022 Oct 04.
Artigo em Inglês | MEDLINE | ID: mdl-36195927

RESUMO

BACKGROUND: The aim of this study was to evaluate the effect of bioactive glass (BAG) 45S5 paste on colour change and tooth sensitivity (TS) when used in combination with 20% carbamide peroxide (CP) during at-home vital tooth bleaching. METHODS: Twenty-four patients were selected and assigned into two experimental groups (n = 12) in a double-blind study design. Each patient received 20% CP followed by the application of either BAG paste or non-active placebo paste. The shade evaluation was performed using a digital spectrophotometer based on the CIE L*a*b* colour space system at different time points and the overall colour changes ΔE were calculated. TS was evaluated using visual analogue scale (VAS). The values of ΔE and TS were statistically analysed using paired t-test. The level of statistical significance was established at p = 0.05. RESULTS: The overall colour changes (ΔE) between baseline and each time point showed no significant differences between BAG and placebo groups (p > 0.05). The use of BAG paste significantly decreased TS reported by the participants. CONCLUSIONS: The association of BAG paste with at-home bleaching treatment presents a promising method as it decreased TS and did not deteriorate bleaching efficacy. Trial registration This study was approved and registered in the Australian New Zealand Clinical Trials Registry (ANZCTR) under Registration number: ACTRN12621001334897.


Assuntos
Sensibilidade da Dentina , Clareadores Dentários , Clareamento Dental , Austrália , Peróxido de Carbamida , Humanos , Peróxidos , Clareamento Dental/efeitos adversos , Clareamento Dental/métodos , Resultado do Tratamento , Ureia
6.
Oper Dent ; 47(5): 492-502, 2022 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-36121729

RESUMO

OBJECTIVES: To compare the risk and intensity of tooth sensitivity (TS) as well the effectiveness of at-home bleaching using two carbamide peroxide bleaching gels, specifically a novel polymeric nanoparticle gel (experimental) and a commercial gel (Opalescence PF, Ultradent, South Jordan, Utah, USA), applied at two application times. METHODS: This multicenter, triple-blind, and split-mouth randomized controlled trial was conducted on 80 healthy adults with canine teeth that were shade A2 or darker. The participants all used the experimental and the control gels on one side of a tray, depending on the group to which they were allocated, for 30 or 60 minutes per day over four weeks. The absolute risk and intensity of TS were assessed daily using the five-point Numeric Rating Scale and the 0-10 Visual Analogue Scale. Color change was evaluated with shade guide units (ΔSGU) and a digital spectrophotometer (ΔEab, ΔE00, and ΔWid) at baseline and 30 days postbleaching. The risk and intensity of TS was evaluated by the McNemar and the Wilcoxon signed-rank tests, respectively. Color change (ΔSGU, ΔEab, ΔE00, and ΔWid) was evaluated by Mann-Whitney and paired t-tests (α=0.05). RESULTS: No differences in the risk and intensity of TS were observed based on the bleaching gels used and the times of application (p>0.05). Thirty days after bleaching, there was no significant difference in color change, in terms of the bleaching gels used or the application times (p>0.05). CONCLUSION: The novel carbamide peroxide polymeric nanoparticles gel, when applied for 30 or 60 minutes, produced effective color change and a low rate of tooth sensitivity, as compared to the control group.


Assuntos
Sensibilidade da Dentina , Nanopartículas , Clareadores Dentários , Clareamento Dental , Peróxido de Carbamida , Géis , Humanos , Peróxido de Hidrogênio , Clareadores Dentários/uso terapêutico , Resultado do Tratamento
7.
Am J Dent ; 35(4): 191-196, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35986934

RESUMO

PURPOSE: To evaluate the influence of diet and exposure to red wine on the treatment velocity, clinical results, postoperative tooth sensitivity, and patient satisfaction after tooth bleaching. METHODS: 45 subjects undergoing home bleaching with 16% carbamide peroxide (CP) were randomly separated into three groups, depending on the restriction of colored food and the use of a red wine mouthwash. Shades of teeth 11 and 21 were assessed using a digital spectrophotometer (VITA Easy Shade) at T0 (before treatment), T7 (7 days after treatment), T15 (15 days after treatment), and T30 (30 days after treatment). The assessments were verified using the CIELab system (values of L*, a*, and b*) and the change in shade was calculated (ΔE, ΔL, Δa, and Δb). RESULTS: No statistically significant differences in ΔE, ΔL, Δa, and Δb were found between the groups. However, at T7, the group restricted from colored foods without red wine mouthwash had meaningful variations in L*, a*, and b*. Statistically, there was no difference in tooth sensitivity between the groups in the 7- and 15-day periods. Patients in the restricted colored foods without red wine mouthwash group were more satisfied after the end of treatment. CLINICAL SIGNIFICANCE: Tooth bleaching with 16% carbamide peroxide may be performed in subjects with colorant-rich diets without influencing the clinical outcome.


Assuntos
Sensibilidade da Dentina , Clareadores Dentários , Clareamento Dental , Vinho , Peróxido de Carbamida , Cor , Sensibilidade da Dentina/tratamento farmacológico , Sensibilidade da Dentina/prevenção & controle , Dieta , Humanos , Peróxido de Hidrogênio , Antissépticos Bucais , Peróxidos/uso terapêutico , Clareamento Dental/métodos , Clareadores Dentários/uso terapêutico , Ureia/uso terapêutico
8.
Rev. Cient. CRO-RJ (Online) ; 7(1): 24-30, Jan-Apr 2022.
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1382138

RESUMO

Objective: The aim of this study was to compare the effectiveness of two bleaching treatment protocols to treat dental staining after orthodontic debonding. Materials and Methods: Twenty four bovine teeth were submitted to orthodontic bracket (Morelli, Edgewise Prescription, Slot 22) bonding (Transbond XT, 3M) and debonding, which were divided into three groups according to the bleaching protocol: hydrogen peroxide 10% (Whiteness, FGM) simulating home bleaching protocol (Home Bleaching Group), hydrogen peroxide 35% Whiteness, FGM) simulating dental office bleaching protocol (Office Bleaching Group) and Control Group, which was not exposed to any dental bleaching protocol, and stored in distilled water at 37°C. The specimens were submitted to the following processes: aging of resin remaining tegs by ultraviolet (UV), staining with coffee solution and tooth bleaching with 10% hydrogen peroxide (G1) and 35% hydrogen peroxide (G2). The color stability analysis (CIE color space L* a* b* was performed with Vita Easyshade Compact spectrophotometer before bonding (T0), after aging and staining processes (T1) and after bleaching treatment (T2). All teeth were stored in distilled water at 37°C between experimental times. The comparison between the groups and time effect evaluation were performed using ANOVA / Tukey ( =0.05) and ANOVA-MR with Bonferroni correction ( =0.016), respectively. Results: The color stability parameters L *, a * and b * indicated, with the exception of GC, a tendency of increase in T1 (G1 - L *: 76.72 ± 13.39; a *: 6.68 ± 3.71; b *: 43.14 ± 4.04 / G2: - L *: 75.78 ± 4.66; a *: 8.13 ± 2.75; b *: 43.42 ± 8.87), which reflected the tendency to decrease brightness in T1, followed by a tendency to return to T0 values (G1 - L *: 82.92 ± 12.16; a *: 4.25 ± 3.68; b *: 39.40 ± 9.49 / G2: - L *: 83.76 ± 8.02; a *: 8.76 ± 4.08; b *: 47.90 ± 5.88). Significant differences were observed in G2 in a * (T1: 8.13 ± 2.75, T2: 8.76 ± 4.08) and b * (T1: 43.42 ± 8.87; T2: 47.90 ± 5.88), indicating that this group did not return to the values presented in T0 (a *: 1.81 ± 1.70; b *: 35.40 ± 5.08) (p <0.05). Conclusion: Based on the results of this study, it can be concluded that home bleaching protocol presented better performance for dental surface whitening in an eventual staining after orthodontic debonding.


Objetivo: O objetivo deste estudo foi comparar a eficácia de dois protocolos de tratamento clareador para manchas dentárias causadas após a descolagem ortodôntica. Materiais e Métodos: Vinte e quatro dentes bovinos foram submetidos à colagem e descolagem de braquetes ortodônticos (Morelli, Prescrição Edgewise, Slot 22") (Transbond XT, 3M), que foram divididos em três grupos de acordo com o protocolo de clareamento: peróxido de hidrogênio 10% (Whiteness, FGM) simulando protocolo de clareamento caseiro (grupo clareamento caseiro), peróxido de hidrogênio 35% Whiteness, FGM) simulando protocolo de clareamento de consultório (grupo clareamento de consultório) e Grupo Controle, que não foi exposto a nenhum protocolo de clareamento dental, armazenado em água destilada a 37ºC. Os corpos de prova foram submetidos aos seguintes processos: envelhecimento das resinas remanescentes por ultravioleta (UV), manchamento em solução de café e clareamento dental com peróxido de hidrogênio 10% (G1) e peróxido de hidrogênio 35% (G2). A análise de estabilidade de cor (sistema CIE L* a* b*) foi realizada com espectrofotômetro Vita Easyshade Compact antes da colagem (T0), após os processos de envelhecimento e manchamento (T1) e após o tratamento clareador (T2). Todos os dentes foram armazenados em água destilada a 37 °C entre os tempos experimentais. A comparação entre os grupos e a avaliação do efeito do tempo foram realizadas utilizando ANOVA/Tukey ( =0,05) e ANOVA-MR com correção de Bonferroni ( =0,016), respectivamente. Resultados: Os parâmetros de estabilidade de cor L *, a* e b* indicaram, com exceção do GC, tendência de aumento em T1 (G1 - L*: 76,72 ± 13,39; a*: 6,68 ± 3,71; b*: 43,14 ± 4,04 / G2: - L* : 75,78 ± 4,66; a*: 8,13 ± 2,75; b*: 43,42 ± 8,87), o que refletiu a tendência de diminuição do brilho em T1, seguido de uma tendência de retorno aos valores de T0 (G1- L*: 82,92 ± 12,16 ; a*: 4,25 ± 3,68; b*: 39,40 ± 9,49 / G2: - L*: 83,76 ± 8,02; a*: 8,76 ± 4,08; b*: 47,90 ± 5,88). Foram observadas diferenças significativas no G2 em a* (T1: 8,13 ± 2,75, T2: 8,76 ± 4,08) e b* (T1: 43,42 ± 8,87; T2: 47,90 ± 5,88), indicando que esse grupo não retornou aos valores apresentados em T0 (a*: 1,81 ± 1,70; b*: 35,40 ± 5,08) (p<0,05). Conclusão: Com base nos resultados deste estudo, pode-se concluir que o protocolo de clareamento caseiro apresentou melhor desempenho para o clareamento da superfície dentária em um eventual manchamento após a descolagem ortodôntica.


Assuntos
Estética Dentária , Clareamento Dental , Descolagem Dentária , Odontologia , Clareadores Dentários
9.
Artigo em Inglês | MEDLINE | ID: mdl-36044700

RESUMO

This study evaluates the effect of two in-office bleaching agents with different compositions on the bond strength to enamel surface. Fifty bovine teeth were divided into five groups (n = 10 teeth per group), according to the bleaching agent used and the time elapsed to perform the restorative procedures: restorative procedures performed without bleaching (control group); bleaching with 35% hydrogen peroxide (HP), with restorative procedures 24 hours or 7 days after bleaching (HP/24h and HP/7d groups, respectively); and bleaching with 35% HP with calcium compost, with restorative procedures 24 hours or 7 days after bleaching (HP AutoMixx/24h and HP AutoMixx/7d groups, respectively). The specimens were stored at 37°C in artificial saliva. Restored teeth were submitted to a micro-shear bond strength test. The specimens were analyzed using a stereoscope to determine the fracture pattern, classified as adhesive, cohesive, or mixed. The results of the bond strength test were evaluated by analysis of variance, with significance set at P < .05. The groups showed similar bond strength values without significant difference among them (P > .05). There was a predominance of the adhesive-type fracture pattern in all groups. The bleaching agents with different compositions showed similar bond strength values when the restoration was performed 24 hours and 7 days after bleaching, and the results were similar to the control group.


Assuntos
Clareadores , Colagem Dentária , Clareadores Dentários , Clareamento Dental , Animais , Clareadores/farmacologia , Bovinos , Resinas Compostas/química , Esmalte Dentário , Análise do Estresse Dentário , Humanos , Peróxido de Hidrogênio , Resistência ao Cisalhamento , Clareamento Dental/métodos
10.
Gen Dent ; 70(5): 35-39, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35993931

RESUMO

The aim of this in vitro study was to compare the efficacy and durability of bleaching with diode lasers over a 9-month period. This study evaluated 27 extracted teeth categorized into 3 bleaching groups (n = 9): 940-nm diode laser, 980-nm diode laser, and 40% hydrogen peroxide whitening gel (control). After the baseline color of the teeth was measured using a spectrophotometer, the teeth underwent dental prophylaxis and their color was measured again. Bleaching treatment was then performed. The color of the teeth was measured immediately after bleaching and 1 day (24 hours), 1 week, 1 month, 3 months, 6 months, and 9 months after bleaching. The Commission Internationale de l'Eclairage (CIE) L*a*b* color change (ΔE*) at each timepoint was calculated and compared using repeated-measures analysis of variance. All bleaching techniques effectively whitened the teeth to a clinically perceptible level (ΔE* > 3.3), and there were no statistically significant differences among the groups (P > 0.05). The mean ΔE* values of the laser groups were not significantly different from the mean value of the control group during the 9-month evaluation period (P > 0.05). However, statistically significant differences among the groups were noted when color measurements at the following timepoints were compared: immediately after bleaching vs 1 day; 1 day vs 1 week; and 3 months vs 6 months (P < 0.05). Use of a 940-nm diode laser, 980-nm diode laser, or conventional hydrogen peroxide gel provided equally effective bleaching. The color change remained clinically perceptible throughout the 9-month period.


Assuntos
Clareadores Dentários , Clareamento Dental , Cor , Humanos , Peróxido de Hidrogênio/uso terapêutico , Lasers Semicondutores/uso terapêutico , Espectrofotometria , Clareamento Dental/métodos , Clareadores Dentários/uso terapêutico
11.
Oper Dent ; 47(4): 425-436, 2022 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-35917237

RESUMO

OBJECTIVE: This study aimed to evaluate the esthetic efficacy, cytotoxicity, and kinetics of decomposition of hydrogen peroxide (H2O2) present in a commercial bleaching gel with 35% H2O2 (BG35%) chemically activated with manganese oxide (MnO2). METHODS AND MATERIALS: After incorporating 2 mg/mL, 6 mg/mL, and 10 mg/mL of MnO2 into BG35%, the stability of pH and temperature of the products were analyzed. To assess the esthetic efficacy (ΔE and ΔWI), the BG35%s with MnO2 were applied for 45 minutes on enamel/dentin discs (DiE/D). BG35% or no treatment were used as positive (PC) and negative (NC) controls, respectively. To analyze the cell viability (CV) and oxidative stress (OXS), the same bleaching protocols were performed on DiE/D adapted to artificial pulp chambers. The extracts (culture medium + gel components that diffused through the discs) were applied to pulp cells and submitted to H2O2 quantification. BG35% with MnO2 that showed the best results was evaluated relative to kinetic decomposition of H2O2, with consequent generation of free radicals (FR) and hydroxyl radicals (OH•). The data were submitted to the one-way analysis of variance complemented by Tukey post-test (α=0.05). Data on kinetics of H2O2 decomposition were submitted to the Student's-t test (α=0.05). RESULTS: All the BG35%s with MnO2 showed stability of pH and temperature, and the gel with 10 mg/mL of this activator had an esthetic efficacy 31% higher than that of the PC (p<0.05). Reduction in OXS and trans-amelodentinal diffusion of H2O2 occurred when all the BG35%s with MnO2 were used. The addition of 6 and 10 mg/mL of MnO2 to BG35% increased the CV in comparison with PC, confirmed by the cell morphology analysis. An increase in FR and OH• formation was observed when 10 mg/mL of MnO2 was added to BG35%. CONCLUSION: Catalysis of BG35% with MnO2 minimized the trans-amelodentinal diffusion of H2O2 and toxicity of the product to pulp cells. BG35% containing 10 mg/mL of MnO2 potentiated the decomposition of H2O2, enhancing the generation of FR and OH•, as well as the efficacy of the in-office tooth therapy.


Assuntos
Clareadores Dentários , Clareamento Dental , Estética Dentária , Humanos , Peróxido de Hidrogênio/química , Compostos de Manganês , Óxidos , Clareamento Dental/métodos
12.
Lasers Med Sci ; 37(8): 3237-3247, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35829976

RESUMO

This study aims to evaluate the effect of diode laser- or LED-activated tooth bleaching on color change, tooth sensitivity(TS), temperature variation, and gingival irritation (GI) for 9 months. Thirty-five subjects having anterior teeth with a color of A2 or darker were enrolled in the study. In a split-mouth design, one side of each arch was activated by a diode laser (Epic X, Biolase), and the other side was activated by an LED (Radii Plus, SDI) in conjunction with a bleaching agent (35%, Whiteness HP). The color change was evaluated by subjective (VitaClassic/Vita3D Master Bleachguide) and objective (spectrophotometer, Vita Easyshade) methods for up to 9 months. TS and GI were assessed by visual analogue scale (VAS) and gingival index, respectively, at the same recall periods. During the bleaching, the temperature variation was also recorded using a thermocouple. Statistical analyses were performed (p < 0.05). In the color evaluation, no statistically significant difference was found between diode laser and LED (p > 0.05), except for the 6-month spectrophotometric assessment (ΔE00, ΔEab), where higher values were obtained with the laser (p < 0.05). The temperature difference and maximum temperature with diode were found to be significantly higher than LED (p < 0.05). Higher values were obtained with LED when the mean temperatures were compared (p < 0.05). There was no difference between the two activation methods in terms of TS and GI at any of the recalls (p > 0.05). The bleaching activated either with diode laser or LED performed similar clinical performance in terms of effective color change, tooth sensitivity, and gingival irritation with minimum temperature variations.


Assuntos
Clareadores , Sensibilidade da Dentina , Clareadores Dentários , Clareamento Dental , Seguimentos , Humanos , Peróxido de Hidrogênio , Lasers Semicondutores/uso terapêutico , Clareamento Dental/métodos , Resultado do Tratamento
13.
Clin Oral Investig ; 26(10): 6387-6395, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35776203

RESUMO

OBJECTIVES: To evaluate in vitro two high concentration self-mix bleaching gels (35% or 37.5%) with different application tips (with or without an applicator brush) during in-office bleaching. MATERIALS AND METHODS: Healthy premolars were randomly assigned to five groups (n = 8): no treatment; 35% HP without applicator brush, 35% HP with applicator brush, 37.5% HP without applicator brush, and 37.5% HP with applicator brush. After the procedures, the concentration of HP transferred into the pulp chamber was evaluated using UV-Vis. The amount of gel used in each group was measured on a precision analytical balance. Color change (ΔEab, ΔE00, and ΔWID) was evaluated with a digital spectrophotometer. Initial concentration was measured by titration with potassium permanganate. The pH was evaluated using a digital pH meter. The data from each test were submitted to nonparametric tests (α = 0.05). RESULTS: Using a tip with an applicator brush expended less gel and left a lower amount of HP inside the pulp chamber compared to the tip without a brush for both bleaching gels (p < 0.0003), although no significant difference in color change was observed (p < 0.05). The 37.5% HP showed a more stable and less acidic pH and a lower amount of HP in the pulp chamber than the 35% HP (p < 0.00001). CONCLUSION: The HP penetration into the pulp chamber was lower when using an applicator with a brush tip than when using one with a conventional tip. As for the color, both tips were considered to lighten teeth. CLINICAL SIGNIFICANCE: For the application of a self-mixing high concentration in-office bleaching gel, a brush tip should be recommended because its use diminishes the penetration of HP into the pulp chamber and wastes less bleaching gel.


Assuntos
Clareadores Dentários , Clareamento Dental , Géis , Peróxido de Hidrogênio , Ácido Hipocloroso , Permanganato de Potássio , Clareamento Dental/métodos
14.
Photodiagnosis Photodyn Ther ; 39: 103028, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35872355

RESUMO

BACKGROUND: Bleaching protocols using low concentration hydrogen peroxide (HP) photoactivated with LED sources have been widely discussed. Herein, we evaluated the whitening efficacy of 15% HP photoactivated with blue or violet LED compared to 35% HP. METHODS: Thirty bovine crowns were sectioned into 5 × 5 × 2 mm specimens. After staining in black tea, the specimens were randomized into three groups (n = 10): 35% HP, 15% HP + blue LED and 15% HP + violet LED. Two bleaching sessions were performed and the color assessment (∆L*, ∆a*, ∆b*, ∆Eab [CIELab], ∆E00 [CIEDE2000] and WID) was performed before, 24h after each session, 7 days and 1 month after the last session. Data were evaluated by two-way repeated measures ANOVA and Bonferroni post-test at a significance level of 5%. RESULTS: All groups showed effective and similar results over 1 month of follow-up (p > 0.05), with only intragroup differences among the time intervals (p < 0.05). CONCLUSIONS: The use of 15% HP photoactivated with blue or violet LED showed similar whitening efficacy compared to 35% HP. Thus, the association of low concentration bleaching gels with blue or violet LED sources can provide successful and less-aggressive treatment in terms of color change.


Assuntos
Fotoquimioterapia , Clareadores Dentários , Clareamento Dental , Animais , Bovinos , Cor , Géis , Peróxido de Hidrogênio , Ácido Hipocloroso , Fotoquimioterapia/métodos , Clareamento Dental/métodos
15.
Oper Dent ; 47(3): E119-E130, 2022 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-35649221

RESUMO

OBJECTIVE: This study investigated the influence of the viscosity and kind of thickener of 35% hydrogen peroxide bleaching gels on the tooth (color change, demineralization of enamel, and permeation) and on the gel [reactive oxygen species (ROS), pH, and peroxide concentration]. METHODS AND MATERIALS: Two hundred forty specimens were divided into groups of bleaching gels with different thickeners (CAR, carbomer; ASE, alkali swellable emulsion; MSA, modified sulfonic acid polymer; SSP, semisynthetic polysaccharide; PAC, particulate colloids) in three viscosities (low: 50,000 cP; medium: 250,000 cP; high: 1,000,000 cP). Color change (ΔEab), demineralization of enamel by Knoop microhardness (KHN) reduction analysis, and peroxide permeation (PP) were analyzed in the specimens, while pH, peroxide concentration (PC), and ROS were evaluated in the gels. Data were analyzed by two-way ANOVA (α=0.05). RESULTS: The higher viscosity gels reduced ΔEab, PP, enamel softening, and ROS in relation to the lower viscosity gels. However, the drop in pH and PC were higher in the more viscous gels. Gels with MSA produced higher ΔEab compared with SSP and ASE. The PP was higher for PAC, and smaller for SSP and CAR. The KHN reduction was higher for CAR and smaller for PAC. The higher pH reduction was seen for ASE and CAR, and the smaller for SSP. The PC reduction was higher for SSP and smaller for CAR. More ROS were observed for MSA and fewer for ASE. CONCLUSIONS: Increased gel viscosity was associated with reduced color change, permeation, demineralization of enamel, and ROS, and led to increased peroxide decomposition and pH alteration during the treatment. The kind of thickener significantly interfered with the treatment effects.


Assuntos
Clareadores Dentários , Clareamento Dental , Desmineralização do Dente , Géis , Dureza , Humanos , Peróxido de Hidrogênio/química , Peróxidos/uso terapêutico , Espécies Reativas de Oxigênio , Clareamento Dental/métodos , Clareadores Dentários/farmacologia , Clareadores Dentários/uso terapêutico , Viscosidade
16.
Oper Dent ; 47(3): 247-257, 2022 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-35653595

RESUMO

OBJECTIVE: To compare the efficacy, color stability, and tooth sensitivity (TS) of combined bleaching, using a modified protocol with at-home bleaching. METHODS: Eighty participants were randomized into two groups. In the combined group, a desensitizing gel was applied (10 minutes) prior to in-office bleaching (35% hydrogen peroxide (H2O2), 2×15 minute applications) and at-home bleaching (4% H2O2, 2×30 minutes for 21 days) started the next day. In the at-home group, only the at-home bleaching was performed. Color was recorded at the beginning and postbleaching with two scales (VITA Classical and Bleachedguide) and Easyshade spectrophotometer. The TS was recorded daily with a 0-10 visual analogue scale (VAS) and five-point numeric rating scale (NRS). RESULTS: A 40% lower risk (RR=1.4; 95% CI 1.1-1.9) was observed in the at-home group. Higher color change and intensity of TS [mean difference 2.3 (95% CI 1.3-3.3) in the VAS] was observed in the first week for the combined group. After the end of the protocol, a bleaching degree was detected for both groups, with no significant difference between both groups (p>0.05). CONCLUSION: The combined group produced a slightly higher degree of color change than at-home bleaching but with a higher risk and intensity of TS.


Assuntos
Sensibilidade da Dentina , Clareadores Dentários , Clareamento Dental , Humanos , Peróxido de Hidrogênio/uso terapêutico , Método Simples-Cego , Clareamento Dental/métodos , Clareadores Dentários/uso terapêutico , Resultado do Tratamento
17.
Oper Dent ; 47(3): 357-365, 2022 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-35671228

RESUMO

OBJECTIVES: The primary objective of this study was to evaluate the effect of an innovative double-layer, single-application desensitizing/whitening technique of potassium nitrate (PN) and hydrogen peroxide (HP) diffusion at different time points. METHODS AND MATERIALS: Specimens were prepared from extracted caries-free human molars (n=90). Teeth were randomly assigned into four groups: Group A (HP CTRL) treated with 25% HP for 45 minutes, group B (PN CTRL) received a single-layer treatment of 5% PN for 45 minutes, group C received the double-layer treatment of 5% PN and 25% HP for 45 minutes, and group D received a 3% PN incorporated in a 40% HP gel for 45 minutes. PN and HP concentrations were measured at 5, 15, 30, and 45 minutes using standard chemical kits. Group comparisons were made using a repeated measures analysis of variance (ANOVA) test. Pairwise tests for differences in diffusion were done, using the Tukey adjustment of p values for multiple comparisons. A significance level of 5% was used. RESULTS: Group A showed no significant difference in HP diffusion rates between the 5- and 15-minute, 15- and 30-minute, or 30- and 45-minute time points; group D showed a similar trend; however, group C differed significantly at the 5-and 15-minute time points (p=0.0004), at the 15-and 30-minute time points (p=0.0026), and the 30- and 45-minute time points (p=0.0014). For PN diffusion, groups B and C had significantly different levels at the 15-, 30-, and 45-minute time points (p=0.0005, p=0.0002, and p<0.0001, respectively); and at the 15-, 30-, and 45-minute time points, groups D and C had significantly different PN diffusion (p=0.0327, p=0.0004, and p< 0.0001, respectively). Group C had significantly different PN diffusion at the 5- and 15-minute time points (p=0.0004), the 15- and 30-minute time points (p=0.0026), and at the 30- and 45-minute time points (p=0.0014). CONCLUSION: The double-layer technique showed superior diffusion of PN into the pulp chamber and did not affect the diffusion of HP when compared to other techniques. The double-layer technique may be suggested as an alternative tooth-whitening treatment to minimize tooth sensitivity.


Assuntos
Cavidade Pulpar , Peróxido de Hidrogênio , Compostos de Potássio , Clareadores Dentários , Clareamento Dental , Humanos , Peróxido de Hidrogênio/farmacocinética , Nitratos/farmacocinética , Compostos de Potássio/farmacocinética , Distribuição Aleatória , Clareamento Dental/métodos , Clareadores Dentários/farmacocinética
18.
Clin Oral Investig ; 26(10): 6361-6369, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35760882

RESUMO

OBJECTIVE: The purpose of this study was to examine the effect of applying two different prophylaxis pastes with various protocols on the degree of bleaching and color stability in the office bleaching process with a bleaching agent containing 40% hydrogen peroxide. MATERIAL AND METHOD: The 300 teeth of 15 (9 female, 6 male) patients were included in our study, and 5 different study groups were randomly formed. The bleaching process with Ultradent Opalescence Boost (Ultradent, South Jordan, USA) was performed according to the manufacturer's instructions. Two different prophylaxis pastes, Ultrapro (Ultradent, Cologne, Germany) and Cleanic (Kerr, Rastatt, Germany), were applied with protocols determined according to the groups. The effect on color stability at 6-, 12-, and 24-month follow-up was determined using the CIE L* a* b* color system. The changes in the parameters were analyzed using the one-way ANOVA, chi-square, and Tukey test (p > 0.05). RESULTS: The evaluation rate of the treatments was 100% at the end of 24 months. Control group 6-month ΔE (0-6) and 12-month ΔE (0-12) values were higher than 24-month ΔE (0-12) values. UU + UU, KC + KC, and UU group 6-month ΔE (0-6) values were higher than 12-month ΔE (0-12) values. In addition, 6-month ΔE (0-6) and 12-month ΔE (0-12) values were higher than 24-month ΔE (0-24) values. KC group 6-month ΔE (0-6) and 12-month ΔE (0-12) values were higher than 24-month ΔE (0-24) values. Control, UU + UU, KC + KC, UU, and KC group ΔE (1-6) values at 6 months were lower than 12-month ΔE (1-12) and 24-month ΔE (1-12) values in all groups. In addition, 12-month ΔE (1-12) values were lower than 24-month ΔE (1-24) values. According to the study data, there was no statistically significant difference between the groups according to the prophylaxis paste and prophylaxis procedure (p > 0.05). However, it was observed that whiteness decreased in all groups over time. CONCLUSIONS: Discoloration was observed at 6 months, 12 months, and 24 months after bleaching. However, at the end of 24 months, the tooth color was significantly whiter than the initial color. CLINICAL RELEVANCE: Pre-bleaching prophylaxis application and pre-bleaching and post-bleaching prophylaxis application have no effect on color stability.


Assuntos
Clareadores , Clareadores Dentários , Clareamento Dental , Cor , Feminino , Seguimentos , Humanos , Peróxido de Hidrogênio , Ácido Hipocloroso , Masculino , Clareamento Dental/métodos , Clareadores Dentários/farmacologia , Clareadores Dentários/uso terapêutico
19.
Photodiagnosis Photodyn Ther ; 39: 102959, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35691564

RESUMO

OBJECTIVES: To evaluate the influence of violet LED, associated or not with a 17.5% hydrogen peroxide (HP) bleaching gel, on inflammation, mineralization in pulp tissue, and collagen fiber maturation in dentin and pulp tissue. MATERIALS AND METHODS: The maxillary molars of eighty Wistar rats were distributed into four groups (n = 10): CONT - without treatment; HP - 30 min application of 17.5% HP; LED - 20 min application of violet LED; and HP+LED - application of PH and violet LED. Rats were euthanized and jaws were processed for histologic and immunohistochemical evaluation (IL-17, IL-23, and osteocalcin) and picrosirius red immediately after (T0), and at 7 (T1), 15 (T2), and 30 days (T3) post-treatment, with Wilcoxon, Mann-Whitney, paired T-test, and T-test (α = 0.05). RESULTS: HP and HP+LED presented necrosis and severe inflammatory infiltrate. When compared to CONT group, LED presented severe osteocalcin (OCN) immunostaining in T2 and less immature fibers in T2 and T3. CONCLUSION: The violet LED caused no severe damage to the pulp tissue, increased IL-17 and IL-23 expression in T0 when associated with HP, and had no influence on pulp tissue mineralization, besides accelerating the maturation of collagen fibers of dentin. CLINICAL RELEVANCE: Violet LED therapy induced no inflammation in the pulp tissue of rats and played no role in pulp tissue fibrosis, besides accelerating the maturation of dentin collagen fibers.


Assuntos
Luzes de Cura Dentária , Polpa Dentária , Dentina , Peróxido de Hidrogênio , Inflamação , Fotoquimioterapia , Clareadores Dentários , Clareamento Dental , Calcificação de Dente , Animais , Colágeno/metabolismo , Polpa Dentária/efeitos dos fármacos , Polpa Dentária/efeitos da radiação , Dentina/efeitos dos fármacos , Dentina/efeitos da radiação , Géis , Peróxido de Hidrogênio/farmacologia , Peróxido de Hidrogênio/uso terapêutico , Inflamação/tratamento farmacológico , Inflamação/radioterapia , Interleucina-17/metabolismo , Interleucina-23/metabolismo , Osteocalcina/metabolismo , Fotoquimioterapia/métodos , Ratos , Ratos Wistar , Clareamento Dental/métodos , Clareadores Dentários/farmacologia , Clareadores Dentários/uso terapêutico , Calcificação de Dente/efeitos dos fármacos , Calcificação de Dente/efeitos da radiação
20.
ACS Nano ; 16(7): 10042-10065, 2022 Jul 26.
Artigo em Inglês | MEDLINE | ID: mdl-35704786

RESUMO

Whitening agents, such as hydrogen peroxide and carbamide peroxide, are currently used in clinical applications for dental esthetic and dental care. However, the free radicals generated by whitening agents cause pathological damage; therefore, their safety issues remain controversial. Furthermore, whitening agents are known to be unstable and short-lived. Since 2001, nanoparticles (NPs) have been researched for use in tooth whitening. Importantly, nanoparticles not only function as abrasives but also release reactive oxygen species and help remineralization. This review outlines the historical development of several NPs based on their whitening effects and side effects. NPs can be categorized into metals or metal oxides, ceramic particles, graphene oxide, and piezoelectric particles. Moreover, the status quo and future prospects are discussed, and recent progress in the development of NPs and their applications in various fields requiring tooth whitening is examined. This review promotes the research and development of next-generation NPs for use in tooth whitening.


Assuntos
Clareadores , Nanopartículas , Clareadores Dentários , Clareadores Dentários/uso terapêutico , Peróxidos , Ureia , Peróxido de Hidrogênio
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