RESUMO
Este manuscrito apresenta trabalhos e ações que a autora do Centro de Imunologia do Instituto Adolfo Lutz de São Paulo (CIM-IAL) pôde executar e com os quais pôde colaborar e que foram importantes para o diagnóstico de novas infecções e infecções negligenciadas relacionadas às epidemias de HIV/Aids, influenza A/H1N1, covid-19/SARS-CoV-2 e às infecções por herpes vírus 8 (HHV-8) e vírus linfotrópicos de células T humanas 1 e 2 (HTLV-1/-2), com ênfase nas publicações do Boletim Epidemiológico Paulista (BEPA). Esses trabalhos foram conduzidos por pesquisadores científicos, estagiários e pós-graduandos e receberam diversos prêmios por serem pioneiros, empregarem novas metodologias e contribuírem para reduzir os custos dos exames para o Sistema Único de Saúde (SUS). Além disso, para dar visibilidade ao HTLV-1 e às doenças a ele relacionadas consideradas negligenciadas, ligadas a determinantes sociais e que não têm cura a partir de 2002 a autora ofereceu aos alunos do Programa de Pós-Graduação em Ciências da Coordenadoria de Controle de Doenças da Secretaria de Estado da Saúde de São Paulo (CCD/SES-SP) uma disciplina específica sobre HTLV e, nos últimos anos, têm divulgado o Dia Mundial do HTLV 10 de novembro, por meio de publicações, exposição de bannerse palestras. Essas iniciativas foram premiadas durante o Evento sobre o Dia Mundial do HTLV, patrocinado pela Organização Pan-Americana da Saúde (OPAS), em 2021.
This manuscript presents papers and actions that the author from the Immunology Center of the Instituto Adolfo Lutz of São Paulo (CIM-IAL) could carry out and collaborate and that were important for the diagnosis of new infections and neglected infections, respectively of the epidemies of HIV/Aids, Influenza A/H1N1, covid-19/SARS-CoV-2, and the herpesvirus 8 (HHV-8) and human T-cell lymphotropic viruses 1 and 2 (HTLV-1/-2) infections, with emphasis on those published in Boletim Epidemiológico Paulista (BEPA). These works were conducted by scientific researchers, trainees and postgraduate students, and they received several awards for being pioneers, employer new methodologies and contribute to reduce the costs of exams for the Brazilian Unified Health System (SUS). In addition, for giving visibility to HTLV-1 and related diseases that were considered neglected diseases linked to social determinants and that have no cure, from 2002 onwards offered to students of the Postgraduate Program in Sciences of the Coordination of Disease Control of São Paulo State Secretary of Health (CCD/SES-SP), a specific course on HTLV, and in the last years, the dissemination of the World HTLV Day November 10th, by publications in magazines, banners inhibition and lectures. These initiatives were awarded during one Webinar on World HTLV Day, sponsored by the Pan American Health Organization (OPAS), 2021.
Assuntos
Distinções e Prêmios , Virologia , Sistema Único de Saúde , HIV , Doenças Negligenciadas , EpidemiasRESUMO
BACKGROUND: Pathogens causing prosthetic joint infection (PJI) are thought to gain access to the knee during surgery or from a remote site in the body. Recent studies have shown that there is a distinct microbiome in various sites of the body. This prospective study, and first of its kind, was set up to investigate the presence of possible microbiome in human knee and compare the profile in different knee conditions. METHODS: We obtained synovial fluid from 65 knees (55 patients) with various conditions that included normal knee, osteoarthritis (OA), aseptic revision, and those undergoing revision for PJI. The contralateral knee of patients who had a PJI were also aspirated for comparison. A minimum of 3 milliliters of synovial fluid was collected per joint. All samples were aliquoted for culture and next-generation sequencing analysis. RESULTS: The highest number of species was found in native osteoarthritic knees (P ≤ .035). Cutibacterium, Staphylococcus, and Paracoccus species were dominant in native nonosteoarthritic knees, and meanwhile a markedly high abundance of Proteobacteria was observed in the osteoarthritic joints. Moreover, the contralateral and aseptic revision knees showed a similar trend in bacterial composition (P = .75). The sequencing analysis of patients who had PJI diagnosis, confirmed the culture results. CONCLUSION: Distinct knee microbiome profiles can be detected in patients who have OA and other knee conditions. The distinct microbiome in the knee joint and the close host-microbe relationships within the knee joint may play a decisive role in the development of OA and PJI.
Assuntos
Artrite Infecciosa , Artroplastia de Quadril , Artroplastia do Joelho , Distinções e Prêmios , Infecções Relacionadas à Prótese , Humanos , Artroplastia do Joelho/efeitos adversos , Artroplastia do Joelho/métodos , Estudos Prospectivos , Infecções Relacionadas à Prótese/etiologia , Articulação do Joelho/cirurgia , Artrite Infecciosa/etiologia , Reoperação/efeitos adversos , Estudos Retrospectivos , Artroplastia de Quadril/efeitos adversosRESUMO
Belisario Domínguez was a Mexican physician, ophthalmologist, and politician. He traveled abroad to France, where he studied High School, later he entered the School of Medicine at Sorbonne University in Paris. Back in Mexico, Domínguez installed his medical office in his house. Belisario was recognized for his philanthropic attitude, he also often sought the well-being being of Chiapas and Mexico. In 1911 he became Comitán Municipal President, after the overthrown of presidente Porfirio Díaz.He witnessed the coup against President Francisco Madero by General Huerta. Belisario wrote a speech in which he expressed the shame of having a traitor and murderer as President. As consequence of the speech, he was killed. After Belisario's assassination, an outrage was incited, damaging the image of President Huerta. Belisario's civic value was honored with a medal that bears his name " Belisario Domínguez Medal" in 1953 which is the greatest recognition that can be obtained by a Mexican.
Assuntos
Distinções e Prêmios , Medicina , Médicos , Humanos , França , NumismáticaRESUMO
Resumo O objetivo principal é analisar a associação entre o casamento e a coabitação e o rendimento do trabalho masculino no Brasil. O artigo discute o fenômeno do "prêmio salarial masculino do casamento" - geralmente, homens casados apresentam rendimentos mais elevados do que os solteiros no mercado de trabalho. Tendo em vista que no Brasil a união informal é uma modalidade conjugal bastante comum, o prêmio para a coabitação também é investigado nessa situação. A associação entre o estado conjugal e o trabalho remunerado dos homens brasileiros é analisada por meio de regressões lineares, quantílicas e decomposições de Oaxaca-Blinder para os diferenciais de rendimentos entre os homens solteiros, casados e coabitantes. O Censo Demográfico de 2010 é a fonte de dados utilizada. Os resultados confirmam a existência de prêmios do casamento e da coabitação para os homens brasileiros. Os prêmios observados tendem a ser menores para a coabitação do que para o casamento. As decomposições dos diferenciais de rendimentos mostram que os prêmios devem-se à estrutura salarial e não a efeitos de composição.
Abstract The article aims to explore the correlation between marriage, cohabitation, and male labor income. It delves into the concept of the "male marriage wage premium" - a phenomenon where married men earn higher wages compared to single men in the labor market. Since consensual unions are prevalent in Brazil, the study also examines the cohabitation premium. The research employs linear regressions, quantile regression, and Blinder-Oaxaca decompositions of earnings differentials between single, married, and cohabiting men to analyze the association between marital status and paid work among Brazilian men. The data utilized were from the 2010 Demographic Census. The results of the study validate the existence of marriage and cohabitation premia for Brazilian men. However, the observed premium tend to be lower for cohabitation than for marriage. The decompositions reveal that these differentials are due to wage structure and not composition effects.
Resumen El objetivo principal es analizar la asociación entre el matrimonio y la cohabitación y las diferencias salariales masculinas en Brasil. El artículo analiza el fenómeno del premio salarial del matrimonio masculino: en general, los hombres casados tienen ingresos más altos que los hombres solteros en el mercado laboral, aunque ya que en Brasil la cohabitación es una modalidad marital muy común, también se investiga el premio de la cohabitación. La asociación entre el estado civil y el trabajo remunerado entre los hombres brasileños se analiza utilizando regresiones lineales, regresión cuantil y descomposiciones Oaxaca-Blinder para los diferenciales salariales entre hombres solteros, casados y en cohabitación. La fuente de datos fue el censo demográfico de 2010. Los resultados confirman la existencia de premios para el matrimonio y la cohabitación, que tienden a ser menores para la cohabitación que para el matrimonio. La descomposición de los diferenciales de ingresos mostró que los premios se deben a la estructura salarial y no a efectos de composición.
Assuntos
Humanos , Masculino , Feminino , Salários e Benefícios , Pessoa Solteira , Distinções e Prêmios , Trabalho , Casamento , Censos , Brasil , Local de Trabalho , Distribuição por Idade , Estado Conjugal , Mercado de Trabalho , Papel de Gênero , Condições de TrabalhoRESUMO
RESUMO Segundo a literatura, um inventário preciso da distribuição das idades de melhor desempenho nas diferentes disciplinas do atletismo pode proporcionar uma informação ímpar na altura de se produzirem planos e programas de treino de longo prazo para eventos ao mais alto nível. O presente estudo tem como objetivo identificar a idade de melhor desempenho dos atletas participantes nos campeonatos de Portugal de atletismo, com referência às disciplinas e setores que caracterizam a competição. Foram consideradas todas as participações medalhadas (pista coberta - PC, n = 2310; ar livre - AL, n = 3161). Os intervalos de confiança para a idade média dos atletas medalhados foram obtidos com recurso ao método de Equações de Estimação Generalizadas. Os resultados indicaram a média de idades, (i) PC, mais baixa no salto com vara feminino (21.60 anos) e no salto em comprimento masculino (24.42 anos), e mais elevada nos 3000 m marcha feminino (25.18 anos) e nos 5000 m marcha masculino (29.70 anos); (ii) AL, mais baixa no salto em comprimento feminino (22.90 anos) e nos 200 m masculino (23.46 anos), e mais elevada nos 5000 m feminino (27.55 anos) e 10000 m marcha masculino (32.23 anos). Os resultados sugerem que as idades de melhor desempenho ocorrem (i) PC, entre os 23 e os 24 anos nas atletas femininas, e os 24 e os 25 nos atletas masculinos; (ii) AL, entre os 23 e os 25 anos nas atletas femininas, e os 24 e 26 anos nos atletas masculinos. O conhecimento objetivo das idades de melhor desempenho nos campeonatos de Portugal de atletismo, por sexo e disciplina, poderá ser uma informação útil para uma gestão eficiente de talentos e das carreiras desportivas.
ABSTRACT According to the literature, a precise inventory of the distribution of the best-performing ages in the different athletics disciplines can provide unique information when producing long-term training plans and programs for events at the highest level. This study aims to identify the age at which athletes participating in the Portuguese athletics championships performed best, with reference to the disciplines and sectors that characterize the competition. All medal-winning participations were considered (indoor track and field, n = 2310; outdoor track and field, n = 3161). Confidence intervals for the average age of medal-winning athletes were obtained using the Generalized Estimating Equations method. The results indicated that the average ages were (i) Indoor track and field - lower in the women's pole vault (21.60 years) and men's long jump (24.42 years), and higher in the women's 3000 m run (25.18 years) and men's 5000 m race walk (29.70 years); (ii) Outdoor track and field - lower in the women's long jump (22.90 years) and men's 200m (23.46 years), and higher in the women's 5000 m (27.55 years) and men's 10000 m race walk (32.23 years). The results suggest that the best-performing ages are (i) Indoor track and field - between 23 and 24 years old in female athletes and 24 and 25 years old in male athletes; (ii) Outdoor track and field - between 23 and 25 years old in female athletes, and 24 and 26 years old in male athletes. Objective knowledge of the best-performing ages in the Portuguese athletics championships by gender and discipline could be useful information for efficient talent and career management.
Assuntos
Humanos , Masculino , Feminino , Adulto , Atletismo , Atletas , Portugal , Distinções e Prêmios , Estatura , Estudos Retrospectivos , Desempenho Atlético/fisiologiaRESUMO
Due to disseminated and metastatic non-Hodking lymphoma, Dr. César Garavagno died at the age of seventy in the city of Talca on Tuesday, September 12, 1943. The following day, he was paid a tribute in Deputies of the National Congress's chamber in Santiago. Thirteen years after his death, in 1956, Talca Hospital was named in honor of his memory, which would later become Regional Hospital. In 1959, being the first provincial surgeon not associated with a university teaching center, he was nominated Master of Chilean Surgery at the annual Surgery Congress. These have been the three posthumous tributes received that magnify and honor his memory, leaving a permanent legacy and vocation of service of medical professionals who work there today and the challenge to local surgeons to organize for third time a National Surgery Congress in Talca.
Assuntos
Humanos , Masculino , História do Século XX , Cirurgia Geral/história , História da Medicina , Distinções e Prêmios , Educação Médica , HospitaisRESUMO
A well-established agenda on the research output, impact, and structure of global scientific elites such as Nobel Prize laureates has generated interest in the scientific elites from developing countries. However, this topic has not been investigated in detail. This study, first, deploys science mapping techniques to provide a comprehensive analysis of the output, impact, and structure of the Colombian scientific elite, i.e., researchers awarded with the Alejandro Ángel Escobar Foundation National Prize 1990-2020, known locally as the Colombian Nobel. Second, we conducted a productivity and impact comparison between the Colombian scientific elite and Nobel Prize laureates in science and economics by means of a stratified random sample 1990-2020 via the composite citation indicator proposed by Ioannidis et al. Findings showed that the Colombian scientific elite has a broader agenda than indexing titles in internationally renowned bibliographic databases. The Colombian scientific elite also showed positive growth, which is an inverse trend compared with the sample of Nobel laureate productivity. There were no noticeable changes in productivity/impact before and after receiving the Alejandro Ángel Escobar Foundation National Prize. Institutional collaboration within the Colombian scientific elite displayed the highest betweenness (brokerage) role of world/local top-tier universities. However, only two Colombian scientific elite members published an article with two Nobel Prize laureates. Most of the research profiles reflected the national output priorities, but were found to diverge from the national focus in respect of strategic research capacities. The interleaving of the Colombian scientific elite and Nobel Prize laureates-particularly between the 3rd and 2nd quartiles-enabled a more nuanced analysis of the local impact in the global scientific landscape. Our findings also contrast with previous findings on the lower research impact of authors from Latin America, despite their involvement as contributors to reputable journals, and also shed light on the research performance-impact standards and agenda between the global North and South and provide an in-context assessment of outstanding local research.
Assuntos
Distinções e Prêmios , Prêmio Nobel , Colômbia , História do Século XX , Humanos , Publicações , PesquisadoresAssuntos
Humanos , Distinções e Prêmios , Livros , Publicação Comemorativa , Pessoas Famosas , HistóriaRESUMO
On the one hand, environmental certifications like the Blue Flag award (BFA) are well-known globally for its role in beach management and tourism attraction. Plastic pollution like microplastics, on the other hand, has become a global concern due to their increasing persistence and negative environmental repercussions. This paper examines and discusses the factors that would lead to (micro)plastics being included to the BFA as a criterion. Thereby, we attempt to maximize BFA's potential as a tool for better understanding (micro)plastics on beaches and implementing strategies to reduce them. The anticipated primary benefits are: 1) knowing the degree of litter disposal and microplastic contamination, 2) conducting close monitoring, 3) having an accessible database for numerous coastlines throughout the world, 4) evaluating management strategies and making improvements, 5) assisting in long-term research, 6) having a responsible entity in charge of issue decision-making, and 7) a larger public/scientific outreach.