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1.
J Environ Manage ; 301: 113890, 2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-34624576

RESUMO

Universal energy access is one of the targets of the Sustainable Development Goals (SDGs), and thus the deployment of electricity grids is expected to expand globally in the coming decades. However, the installation of power lines is not biodiversity-friendly. In particular, electrocution on power pylons is a major cause of bird mortality worldwide, including for some severely endangered species. Over the last decades, different studies have improved our understanding of the factors influencing the risk of electrocution in birds, but until now spatial gaps in our knowledge of these impacts and the factors driving global patterns of bird electrocution have not been assessed. In this study, we evaluated data from a total of 114 studies that provided information on bird mortality rates on power lines, and we analyzed the factors driving electrocution rates for all bird species, and then for all raptors and large eagles separately. Our results showed a high spatial distribution bias, as more than 80% of the studies were carried out in developed countries, mostly in Europe and North America. By contrast, no systematic studies have been found for Oceania and very few for South America and Africa. Europe showed the highest electrocution rates for birds, South America for raptor species and Africa for eagles. Socio-economic factors best-explained bird and raptor electrocution rates, while climate-related factors were the most influential for eagles. Contrary to our expectations, factors related to pylon design were the least influential on overall electrocution rates. Variables related to study design showed highly variable levels of influence. This could be due to the lack of standardized protocols. Although bird electrocution has been extensively studied, there are large areas where no studies have been carried out or for which data are inaccessible. This could be because in these areas the power distribution network is still sparse, or that most studies are not public or accessible to the international community. Researchers and managers should promote the publication of studies, as awareness is the first step to solving these problems. The factors identified could be applied globally to the design and planning of power grids and the identification of mortality hotspots. This would help mitigate the creation of new mortality hotspots, especially in developing countries where the installation of new power lines has been growing exponentially in recent years.


Assuntos
Aves , Espécies em Perigo de Extinção , Animais , Biodiversidade , Eletricidade , Europa (Continente)
2.
Sci Total Environ ; 803: 149875, 2022 Jan 10.
Artigo em Inglês | MEDLINE | ID: mdl-34478901

RESUMO

Invasive alien fishes have had pernicious ecological and economic impacts on both aquatic ecosystems and human societies. However, a comprehensive and collective assessment of their monetary costs is still lacking. In this study, we collected and reviewed reported data on the economic impacts of invasive alien fishes using InvaCost, the most comprehensive global database of invasion costs. We analysed how total (i.e. both observed and potential/predicted) and observed (i.e. empirically incurred only) costs of fish invasions are distributed geographically and temporally and assessed which socioeconomic sectors are most affected. Fish invasions have potentially caused the economic loss of at least US$37.08 billion (US2017 value) globally, from just 27 reported species. North America reported the highest costs (>85% of the total economic loss), followed by Europe, Oceania and Asia, with no costs yet reported from Africa or South America. Only 6.6% of the total reported costs were from invasive alien marine fish. The costs that were observed amounted to US$2.28 billion (6.1% of total costs), indicating that the costs of damage caused by invasive alien fishes are often extrapolated and/or difficult to quantify. Most of the observed costs were related to damage and resource losses (89%). Observed costs mainly affected public and social welfare (63%), with the remainder borne by fisheries, authorities and stakeholders through management actions, environmental, and mixed sectors. Total costs related to fish invasions have increased significantly over time, from

Assuntos
Ecossistema , Espécies Introduzidas , Animais , Europa (Continente) , Pesqueiros , Peixes , Humanos
3.
Sci Total Environ ; 803: 149892, 2022 Jan 10.
Artigo em Inglês | MEDLINE | ID: mdl-34500281

RESUMO

The construction sector is the biggest driver of resource consumption and waste generation in Europe. The European Union (EU) is making efforts to move from its traditional linear resource and waste management system in the construction sector to a level of high circularity. Based on the theory of circular economy, a new paradigm called waste hierarchy was introduced in the EU Waste Framework Directive. This work uses the framework of the waste hierarchy to analyze the practice of construction and demolition waste (CDW) management in Europe. We explore the evolution of the waste hierarchy in Europe and how it compares with the circular economy. Then, based on the framework, we analyze the performance of CDW management in each EU member state. Innovative treatment methods of CDW, focusing on waste concrete, is investigated. This brings insight into optimizing and upgrading the CDW management in light of advanced technologies and steering the pathway for transitioning the EU towards a circular society.


Assuntos
Indústria da Construção , Gerenciamento de Resíduos , Materiais de Construção , Europa (Continente) , Resíduos Industriais/análise , Reciclagem
4.
J Med Virol ; 94(1): 197-204, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34427922

RESUMO

Coronavirus disease 2019 (COVID-19) has had different waves within the same country. The spread rate and severity showed different properties within the COVID-19 different waves. The present work aims to compare the spread and the severity of the different waves using the available data of confirmed COVID-19 cases and death cases. Real-data sets collected from the Johns Hopkins University Center for Systems Science were used to perform a comparative study between COVID-19 different waves in 12 countries with the highest total performed tests for severe acute respiratory syndrome coronavirus 2 detection in the world (Italy, Brazil, Japan, Germany, Spain, India, USA, UAE, Poland, Colombia, Turkey, and Switzerland). The total number of confirmed cases and death cases in different waves of COVID-19 were compared to that of the previous one for equivalent periods. The total number of death cases in each wave was presented as a percentage of the total number of confirmed cases for the same periods. In all the selected 12 countries, Wave 2 had a much higher number of confirmed cases than that in Wave 1. However, the death cases increase was not comparable with that of the confirmed cases to the extent that some countries had lower death cases than in Wave 1, UAE, and Spain. The death cases as a percentage of the total number of confirmed cases in Wave 1 were much higher than that in Wave 2. Some countries have had Waves 3 and 4. Waves 3 and 4 have had lower confirmed cases than Wave 2, however, the death cases were variable in different countries. The death cases in Waves 3 and 4 were similar to or higher than Wave 2 in most countries. Wave 2 of COVID-19 had a much higher spread rate but much lower severity resulting in a lower death rate in Wave 2 compared with that of the first wave. Waves 3 and 4 have had lower confirmed cases than Wave 2; that could be due to the presence of appropriate treatment and vaccination. However, that was not reflected in the death cases, which were similar to or higher than Wave 2 in most countries. Further studies are needed to explain these findings.


Assuntos
Vacinas contra COVID-19 , COVID-19/epidemiologia , SARS-CoV-2/genética , Ásia/epidemiologia , COVID-19/mortalidade , COVID-19/transmissão , COVID-19/virologia , Europa (Continente)/epidemiologia , Saúde Global , Humanos , Mutação , Índice de Gravidade de Doença , América do Sul/epidemiologia , Estados Unidos/epidemiologia
5.
Food Chem ; 371: 131178, 2022 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-34583186

RESUMO

New microplasma source optical emission spectrometry (OES) for the determination of Na, K, Mg, Ca, and Zn in wine was developed. As the microplasma source, a solution anode glow discharge (SAGD) or a solution cathode glow discharge (SCGD) were employed. The diluted samples solutions (0.5-2%) were directly analyzed (no acid digestion required) and the detection limits of Na, K, Mg, Ca, and Zn were 0.015, 0.03, 3, 12, and 0.1 µg L-1, respectively. The developed method was used for the analysis of wine samples from the province of Lower Silesia (Poland). It was found that 1) red wines were characterized by a higher content of K and Mg, 2) it was possible to discriminate between Regent and Pinot Noir grape varieties (both red) by the concentrations of K and Ca, 3) the concentration of Na in the analyzed wines was lower than that found in wines from other European countries.


Assuntos
Vitis , Vinho , Europa (Continente) , Polônia , Análise Espectral , Vinho/análise
6.
Sex Reprod Health Matters ; 29(1): 1985814, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34730066

RESUMO

Medical abortion (MA) is recommended by the WHO as a safe and effective pregnancy termination method in the first trimester. From a feminist perspective, it is a non-medicalised, self-managed, emancipating procedure allowing persons seeking abortion to be more in control of their abortion, as opposed to surgical procedures. In European countries where MA is legal, the proportion of MA (relative to surgical abortions) varies greatly. We hypothesised that this ratio may be partly explained by country-level dimensions of gender equality. We assessed the association between MA ratios and gender equality in Europe in correlation and regression analyses, using several country-level gender equality indices. The relevance of other factors, i.e. date of introduction of MA and pregnancy week until which MA is permitted, was also investigated. MA ratios ranged from 24.4% (Italy) to 97.7% (Finland). MA was more frequent relative to surgical abortion in countries with higher levels of gender equality. All gender equality indices were associated with MA ratios (e.g. Global Gender Gap Index corr. coeff: 0.761, p < 0.0001). Specifically, markers of economic and political gender equality seemed to drive the correlations. The pregnancy week until which MA is permitted was associated with both gender equality and MA ratios. Our study suggests that women's participation in the economic and political sphere may have repercussions on the methods offered and used through abortion services. It highlights the link between feminist perspectives, reproductive health policies and practices, and gender equality, especially in terms of access to economic resources and political representation.


Assuntos
Aborto Induzido , Equidade de Gênero , Correlação de Dados , Europa (Continente) , Feminino , Política de Saúde , Humanos , Gravidez
7.
Acta Clin Croat ; 60(2): 282-289, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34744279

RESUMO

The aim was to study functional abilities and to create functional classification of children with cerebral palsy (CP) in Krapina-Zagorje County, based on the classification of gross and fine motor skills and associated impairments. Classification was performed according to the SCPE (Surveillance of Cerebral Palsy in Europe) criteria. We used standardized and complementary functional classification systems for cerebral palsy to create a functional profile. Research included 44 children with CP in the age range of 4 to 18 years. The results showed that the majority of children had bilateral spastic CP (63.6%), followed by unilateral spastic (22.7%) while the representation of dyskinetic CP was 9.09% and ataxic CP 4.55%. Based on the classification of gross and fine motor skills, 43.2% of children had the ability to walk, 11% of children could walk with assistive mobility devices, while 45.4% of children had a low functional level. The study also analyzed the associated impairments where higher classification score of motor impairment correlated with the severity of impairment. The results showed that children with dyskinetic CP and severe motor impairment could have mild cognitive impairment. We systematically present the neuropsychological and functional profile according to the CP type.


Assuntos
Paralisia Cerebral , Doenças Genéticas Inatas , Adolescente , Ataxia , Paralisia Cerebral/complicações , Paralisia Cerebral/epidemiologia , Criança , Pré-Escolar , Europa (Continente) , Humanos , Destreza Motora , Índice de Gravidade de Doença , Caminhada
8.
Health Res Policy Syst ; 19(1): 136, 2021 Nov 07.
Artigo em Inglês | MEDLINE | ID: mdl-34743712

RESUMO

BACKGROUND: The ability to successfully transfer knowledge across international boundaries to improve health across the European Region is dependent on an in-depth understanding of the many factors involved in policy creation. Across countries we can observe various approaches to evidence usage in the policy-making process. This study, which was a part of the Models of Child Health Appraised (MOCHA) project assessing patterns of children's primary care in Europe, focused on how and what kind of evidence is used in child health policy-making processes in European countries and how it is applied to inform policy and practice. METHOD: In this study, a qualitative approach was used. The data were analysed in accordance with the thematic analysis protocol. The MOCHA project methodology relies on experienced country agents (CA) recruited for the project and paid to deliver child health data in each of 30 European countries. CAs are national experts in the child health field who defined the country-specific structured information and data. A questionnaire designed as a semi-structured survey instrument asked CAs to indicate the sources of evidence used in the policy-making process and what needed to be in place to support evidence uptake in policy and practice. RESULTS: In our data we observed two approaches to evidence usage in child health policy formulation. The scientific approach in our understanding refers to the so-called bottom-up initiatives of academia which identify and respond to the population's needs. Institutional approaches can be informed by scientific resources as well; however, the driving forces here are governmental institutions, whose decisions and choices are based not only on the population needs but also on political, economic and organizational factors. The evidence used in Europe can also be of an external or internal nature. Various factors can affect the use of evidence in child health policy-making. Facilitators are correlated with strong scientific culture development, whereas barriers are defined by a poor tradition of implementing changes based on reliable evidence. CONCLUSIONS: Focusing on the facilitators and actively working to reduce the barriers can perceivably lead to faster and more robust policy-making, including the development of a culture of scientific grounding in policy creation.


Assuntos
Saúde da Criança , Formulação de Políticas , Criança , Europa (Continente) , Política de Saúde , Humanos , Inquéritos e Questionários
9.
Schweiz Arch Tierheilkd ; 164(10): 651-659, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34758957

RESUMO

INTRODUCTION: African Swine Fever (ASF) is a severe viral disease infecting all suid species. Since the first outbreak in Georgia in 2007, it has slowly spread towards Western Europe and reached the European Union when first cases were detected in Poland and the Baltic States in 2014. ASF was first reported in China in 2018 and since then, it has spread to 14 countries within two years. This study aimed to estimate the introduction probability of ASF from Eastern Asia in a qualitative risk assessment, and to compare it to the probability from Eastern Europe, which was assessed in an earlier risk assessment. A high probability of introduction was estimated for the import of meat and meat products, which was found to be the most likely route of introduction. Less important routes were introduction by human contamination (low probability) or import of feed or blood products (very low probability). Import of domestic pigs or free-ranging wild boar, contaminated means of transport, or infected semen, embryo or ticks were all estimated to be negligible. For Eastern Europe, import of meat and meat products was also estimated to pose a high risk and was therefore the most likely route of introduction. Higher probabilities were estimated for import of live pigs, contaminated feed or means of transport and human contamination. Overall, the probability of introduction from Eastern Asia is only slightly lower than from Eastern Europe. As it is important to detect the first case as quickly as possible, it is important not to fall victim to habituation effects, but to remain vigilant.


Assuntos
Vírus da Febre Suína Africana , Febre Suína Africana , Doenças dos Suínos , Febre Suína Africana/epidemiologia , Animais , Europa (Continente)/epidemiologia , Extremo Oriente , Polônia , Probabilidade , Sus scrofa , Suínos , Doenças dos Suínos/epidemiologia
10.
J Hist Dent ; 69(2): 129-130, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34734794

RESUMO

In the late 18th and early 19th century American-trained dentists were perceived by the public to be superior to locally trained dentists in many parts of Europe. Some individuals traveled to the United States for training. Other dentists simply claimed falsely to have an American degree or received one through the mail from one of several dental school diploma mills operating in the United States.


Assuntos
Cardiologia , Odontólogos , Europa (Continente) , Humanos , Estados Unidos
11.
Assist Inferm Ric ; 40(3): 131-136, 2021.
Artigo em Italiano | MEDLINE | ID: mdl-34783315

RESUMO

. Family and Community nursing: overview of practice in Europe. In this contribution, an overview of the role and functions of the family nurse in some European countries is presented. The role of family and community nursing varies with respect to contexts and changes according to the needs of the population, focusing particularly on frail conditions, or maternal and child support, or the prevention and management of chronic diseases. Family and community nurses have specialized postgraduate training, except in Finland, to gain skills to help individuals and families prevent disease conditions or cope with chronic disability. They work primarily in community centers, in patients' homes, and with families; advocate for lifestyle modification and behavioral risk factors; and care for families on wide-ranging health issues.


Assuntos
Enfermagem em Saúde Pública , Europa (Continente) , Humanos , Atenção Primária à Saúde
12.
Front Public Health ; 9: 722943, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34746078

RESUMO

Background: Point of care testing (POCT) for infectious diseases is testing conducted near the patient. It allows clinicians to offer the most appropriate treatment more quickly. As POCT devices have increased in accuracy and become more cost-effective, their use has grown, but a systematic assessment of their use for clinical and public health management of infectious diseases in EU/EEA countries has not been previously undertaken. Methods: A scoping review of the literature on POCT in EU/ EEA countries as at November 2019, and a survey of key stakeholders. Results: 350 relevant articles were identified and 54 survey responses from 26 EU/EEA countries were analysed. POCT is available for a range of infectious diseases and in all countries responding to the survey (for at least one disease). POCT is commonly available for influenza, HIV/AIDS, Legionnaires' disease and malaria, where it is used in at least half of EU/EEA countries. While POCT has the potential to support many improvements to clinical care of infectious diseases (e.g., faster diagnosis, more appropriate use of antimicrobials), the results suggest POCT is infrequently used to support public health functions (e.g., disease surveillance and reporting). Conclusion: Although POCT is in use to some extent in all EU/EEA countries, the full benefits of POCT in wider public health functions have yet to be realised. Further research on barriers and facilitators to implementation is warranted.


Assuntos
Doenças Transmissíveis , Influenza Humana , Malária , Doenças Transmissíveis/diagnóstico , Europa (Continente) , Humanos , Malária/diagnóstico , Testes Imediatos
13.
Lancet Public Health ; 6(11): e848-e857, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34756168

RESUMO

BACKGROUND: Adverse childhood experiences (ACEs) are associated with increased health risks across the life course. We aimed to estimate the annual health and financial burden of ACEs for 28 European countries. METHODS: In this systematic review and meta-analysis, we searched MEDLINE, CINAHL, PsycINFO, Applied Social Sciences Index and Abstracts, Criminal Justice Databases, and Education Resources Information Center for quantitative studies (published Jan 1, 1990, to Sept 8, 2020) that reported prevalence of ACEs and risks of health outcomes associated with ACEs. Pooled relative risks were calculated for associations between ACEs and harmful alcohol use, smoking, illicit drug use, high body-mass index, depression, anxiety, interpersonal violence, cancer, type 2 diabetes, cardiovascular disease, stroke, and respiratory disease. Country-level ACE prevalence was calculated using available data. Country-level population attributable fractions (PAFs) due to ACEs were generated and applied to 2019 estimates of disability-adjusted life-years. Financial costs (US$ in 2019) were estimated using an adapted human capital approach. FINDINGS: In most countries, interpersonal violence had the largest PAFs due to ACEs (range 14·7-53·5%), followed by harmful alcohol use (15·7-45·0%), illicit drug use (15·2-44·9%), and anxiety (13·9%-44·8%). Harmful alcohol use, smoking, and cancer had the highest ACE-attributable costs in many countries. Total ACE-attributable costs ranged from $0·1 billion (Montenegro) to $129·4 billion (Germany) and were equivalent to between 1·1% (Sweden and Turkey) and 6·0% (Ukraine) of nations' gross domestic products. INTERPRETATION: Availability of ACE data varies widely between countries and country-level estimates cannot be directly compared. However, findings suggest ACEs are associated with major health and financial costs across European countries. The cost of not investing to prevent ACEs must be recognised, particularly as countries look to recover from the COVID-19 pandemic, which interrupted services and education, and potentially increased risk factors for ACEs. FUNDING: WHO Regional Office for Europe.


Assuntos
Experiências Adversas da Infância/economia , Custos de Cuidados de Saúde/estatística & dados numéricos , Europa (Continente) , Humanos
14.
Rev Prat ; 71(7): 768-772, 2021 Sep.
Artigo em Francês | MEDLINE | ID: mdl-34792917

RESUMO

ALLERGIC-LOOKING CONJUNCTIVITIS IN CHILDREN Eye allergies are constantly on the rise in Europe and around the world. It is a common pediatric pathology in general medicine consultation. It is important to know the different clinical forms of the disease so as not to ignore the serious forms and to be able to refer them to the ophthalmologist.


Assuntos
Conjuntivite Alérgica , Criança , Conjuntivite Alérgica/diagnóstico , Conjuntivite Alérgica/epidemiologia , Conjuntivite Alérgica/terapia , Europa (Continente) , Humanos
15.
Maturitas ; 154: 1-6, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34736574

RESUMO

OBJECTIVE: Gynecologic Sarcomas are rare, aggressive tumors. The aim of this study was to explore the incidence and outcomes of gynecologic sarcomas in a large national data registry and to compare them with reports from other countries. STUDY DESIGN: Records of gynecologic sarcomas diagnosed in Israel (1980-2014) were extracted from the National Cancer Registry and classified according to International Classification of Diseases for Oncology-3 and characterized according to anatomical site, morphology and demographics. Age-standardized incidence rates and 1, 3, 5 and 10-year relative survival rates were calculated for 3 time periods (1980-1994, 1995-2001 and 2005-2014) according to patient age, stage and years of diagnosis. RESULTS: During 1980-2014, 1271 new gynecologic sarcomas were diagnosed in Israel, with incidence slightly increasing in 1980-2004, to an age-standardized incidence rate of 13 per million women. The most common histologic diagnosis was leiomyosarcoma (48%) and the most common anatomical site was the uterus (89%). The age-standardized incidence rate for uterine sarcoma is higher in Israel (10.55 per million) than in England (7.4 per million) and Germany (5.8 per million) respectively. The 5-year overall survival was significantly poorer in patients >70-years, as compared to younger patients (p<0.001) and in those with leiomyosarcoma compared to endometrial stromal sarcoma (p<0.001). The survival rate of patients with leiomyosarcoma in Israel are comparable to survival rates reported by other studies, although substantially lower regarding endometrial stromal sarcoma. CONCLUSIONS: Uterine leiomyosarcoma was the most common gynecologic sarcoma found in the Israeli, European and American registries. Older patients and those with leiomyosarcoma have the worst prognoses. Histological and anatomical variations in Israel are comparable with global statistics, but the incidence in Israel seems higher than in Europe.


Assuntos
Leiomiossarcoma/epidemiologia , Sarcoma/epidemiologia , Neoplasias Uterinas/epidemiologia , Adolescente , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Europa (Continente)/epidemiologia , Feminino , Humanos , Incidência , Lactente , Recém-Nascido , Israel/epidemiologia , Leiomiossarcoma/etnologia , Pessoa de Meia-Idade , Sistema de Registros , Sarcoma/etnologia , Estados Unidos/epidemiologia , Neoplasias Uterinas/etnologia , Adulto Jovem
16.
Acta Vet Scand ; 63(1): 48, 2021 Nov 25.
Artigo em Inglês | MEDLINE | ID: mdl-34823556

RESUMO

Prion diseases are fatal neurodegenerative disorders with known natural occurrence in humans and a few other mammalian species. The diseases are experimentally transmissible, and the agent is derived from the host-encoded cellular prion protein (PrPC), which is misfolded into a pathogenic conformer, designated PrPSc (scrapie). Aggregates of PrPSc molecules, constitute proteinaceous infectious particles, known as prions. Classical scrapie in sheep and goats and chronic wasting disease (CWD) in cervids are known to be infectious under natural conditions. In CWD, infected animals can shed prions via bodily excretions, allowing direct host-to-host transmission or indirectly via prion-contaminated environments. The robustness of prions means that transmission via the latter route can be highly successful and has meant that limiting the spread of CWD has proven difficult. In 2016, CWD was diagnosed for the first time in Europe, in reindeer (Rangifer tarandus) and European moose (Alces alces). Both were diagnosed in Norway, and, subsequently, more cases were detected in a semi-isolated wild reindeer population in the Nordfjella area, in which the first case was identified. This population was culled, and all reindeer (approximately 2400) were tested for CWD; 18 positive animals, in addition to the first diagnosed case, were found. After two years and around 25,900 negative tests from reindeer (about 6500 from wild and 19,400 from semi-domesticated) in Norway, a new case was diagnosed in a wild reindeer buck on Hardangervidda, south of the Nordfjella area, in 2020. Further cases of CWD were also identified in moose, with a total of eight in Norway, four in Sweden, and two cases in Finland. The mean age of these cases is 14.7 years, and the pathological features are different from North American CWD and from the Norwegian reindeer cases, resembling atypical prion diseases such as Nor98/atypical scrapie and H- and L-forms of BSE. In this review, these moose cases are referred to as atypical CWD. In addition, two cases were diagnosed in red deer (Cervus elaphus) in Norway. The emergence of CWD in Europe is a threat to European cervid populations, and, potentially, a food-safety challenge, calling for a swift, evidence-based response. Here, we review data on surveillance, epidemiology, and disease characteristics, including prion strain features of the newly identified European CWD agents.


Assuntos
Cervos , Príons , Scrapie , Doenças dos Ovinos , Doença de Emaciação Crônica , Animais , Europa (Continente) , Príons/genética , Ovinos , Doença de Emaciação Crônica/epidemiologia
17.
Praxis (Bern 1994) ; 110(15): 907-913, 2021 Nov.
Artigo em Alemão | MEDLINE | ID: mdl-34814717

RESUMO

Pediatric Palliative Care - When the End Comes with the Beginning Abstract. Palliative care is not usually associated with childhood and adolescence. Nevertheless, in German-speaking Europe alone, more than 50 000 children live with life-shortening illnesses, and about 5000 children die every year. Palliative care for children and adolescents (PPC) is an attitude that must not be forced on anyone, but must be lived; and, in the case of complex-chronic diseases often over many years. A successful and sustainable implementation of PPC is therefore based on an appreciative collaboration between different teams and the affected families, true to the quadriga presented here of comprehensive symptom control with curiosity, patience, activity and humility. Necessary basics such as the care plan, interprofessional home visits and the round table, plus 24-hour accessibility, are here presented, as well as a triage technique and the advanced care management.


Assuntos
Cuidados Paliativos , Adolescente , Criança , Doença Crônica , Europa (Continente) , Humanos
18.
Yi Chuan ; 43(11): 1011-1022, 2021 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-34815205

RESUMO

Familial hypercholesterolemia (FH) is an autosomal inherited disease characterized by a significant increase in low density lipoprotein cholesterol (LDL-C), tendon xanthoma and premature coronary artery disease (PCAD). In this paper, we analyze the current research status of FH, summarize the reported mutation gene loci in Chinese FH patients and treatment for them, and elaborate the current status of patents and drug researches. The results show that scientific outcomes of FH are increasing with a good developmental trend and the most popular topics of FH study are pathogenesis, treatment of FH, and research on juvenile FH patients. In terms of patents, large pharmaceutical companies, such as Regeneron Pharmaceuticals Inc, AstraZeneca Plc, Merck & Co Inc, are actively engaged in FH detection, diagnosis and treatment. In addition, 12 drugs have been launched in the United States, Japan, Europe and other countries or regions, bringing hope to FH patients.


Assuntos
Doença da Artéria Coronariana , Hiperlipoproteinemia Tipo II , LDL-Colesterol/genética , Europa (Continente) , Humanos , Hiperlipoproteinemia Tipo II/tratamento farmacológico , Hiperlipoproteinemia Tipo II/genética , Mutação , Estados Unidos
19.
Proc Natl Acad Sci U S A ; 118(46)2021 11 16.
Artigo em Inglês | MEDLINE | ID: mdl-34772803

RESUMO

PRACE (Partnership for Advanced Computing in Europe), an international not-for-profit association that brings together the five largest European supercomputing centers and involves 26 European countries, has allocated more than half a billion core hours to computer simulations to fight the COVID-19 pandemic. Alongside experiments, these simulations are a pillar of research to assess the risks of different scenarios and investigate mitigation strategies. While the world deals with the subsequent waves of the pandemic, we present a reflection on the use of urgent supercomputing for global societal challenges and crisis management.


Assuntos
COVID-19/epidemiologia , Computação em Informática Médica/normas , Europa (Continente) , Humanos , Disseminação de Informação , Sistemas de Informação/normas , Computação em Informática Médica/tendências
20.
Euro Surveill ; 26(46)2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34794534

RESUMO

We present a European Union/European Economic Area-wide overview of the changes in consumption of antibacterials for systemic use (ATC J01) in the community between 2019 and 2020 as reported to the European Surveillance of Antimicrobial Consumption Network. Overall antibiotic consumption decreased by 18.3% between 2019 and 2020, the largest annual decrease in the network's two-decade history. We observed a strong association between the level of community antibiotic consumption in 2019 and the size of the decrease between 2019 and 2020.


Assuntos
Antibacterianos , COVID-19 , Antibacterianos/uso terapêutico , Uso de Medicamentos , Europa (Continente)/epidemiologia , União Europeia , Humanos , Pandemias/prevenção & controle , SARS-CoV-2
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