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1.
Cutis ; 109(2): 98-100, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35659800

RESUMO

Highly textured hair has been found to be more susceptible to breakage than other hair types due to an increased proportion of spirals and relatively fewer elastic fibers anchoring the hair follicles to the dermis. Women of African descent frequently employ hairstyles and hair treatments for ease of management and as a form of self-expression, but a number of these practices have been implicated as risk factors for alopecia. Herein, we provide an overview of hairstyles for patients with highly textured hair so that physicians may better identify high-risk hairstyles, provide individualized recommendations for safer alternatives, and manage and stop the progression of hair loss before it becomes permanent.


Assuntos
Alopecia , Folículo Piloso , Preparações para Cabelo , Alopecia/etnologia , Alopecia/prevenção & controle , Feminino , Folículo Piloso/lesões , Preparações para Cabelo/efeitos adversos , Humanos
2.
Artigo em Inglês | MEDLINE | ID: mdl-35409860

RESUMO

INTRODUCTION: Exposure to hazardous chemicals released during hairdressing activities from hair care products puts hairdressers at risk of adverse health effects. Safety assessments of hair products are mainly focused on consumers, but exposure for professional hairdressers might be substantially higher. OBJECTIVE: To identify and assess available research data on inhalation exposures of professional hairdressers. METHODS: A systematic search of studies between 1 January 2000 and 30 April 2021 was performed in Medline, Embase, Web of Science and in Cochrane registry, toxicological dossiers of the Scientific Committee on Consumer Safety (SCCS) of the European Commission as well as the German MAK Commission. Studies reporting quantitative data on airborne concentrations of chemicals in the hairdresser's workplace were considered. The outcome was an airborne concentration of chemicals in the working environment, which was compared, when possible, with current occupational exposure limits (OEL) or guidance levels. RESULTS: In total, 23 studies performed in 14 countries were included. The average number of hairdressing salons per study was 22 (range 1-62). Chemicals most frequently measured were formaldehyde (n = 8), ammonia (n = 5), total volatile organic compounds (TVOC) (n = 5), and toluene (n = 4). More than fifty other chemicals were measured in one to three studies, including various aromatic and aliphatic organic solvents, hydrogen peroxide, persulfate, and particulate matter. Most studies reported environmental air concentrations, while personal exposure was measured only in seven studies. The measured air concentrations of formaldehyde, ammonia, and TVOC exceeded OEL or guidance values in some studies. There was large variability in measuring conditions and reported air concentrations differed strongly within and between studies. CONCLUSION: Hairdressers are exposed to a wide spectrum of hazardous chemicals, often simultaneously. Airborne concentrations of pollutants depend on salon characteristics such as ventilation and the number of customers but also on used products that are often country- or client-specific. For exposure to formaldehyde, ammonia, and TVOC exceeding OELs or guidance values for indoor air was observed. Therefore, occupational exposure should be taken into account by safety regulations for hair care products.


Assuntos
Preparações para Cabelo , Exposição Ocupacional , Compostos Orgânicos Voláteis , Amônia/análise , Formaldeído/toxicidade , Substâncias Perigosas , Humanos , Exposição Ocupacional/efeitos adversos
3.
Soft Matter ; 18(14): 2767-2775, 2022 Apr 06.
Artigo em Inglês | MEDLINE | ID: mdl-35315468

RESUMO

Combing hair involves brushing away the topological tangles in a collective curl, defined as a bundle of interacting elastic filaments. Using a combination of experiment and computation, we study this problem that naturally links topology, geometry and mechanics. Observations show that the dominant interactions in hair are those of a two-body nature, corresponding to a braided homochiral double helix. This minimal model allows us to study the detangling of an elastic double helix driven by a single stiff tine that moves along it and leaves two untangled filaments in its wake. Our results quantify how the mechanics of detangling correlates with the dynamics of a topological quantity, the link density, that propagates ahead of the tine and flows out the free end as a link current. This in turn provides a measure of the maximum characteristic length of a single combing stroke in the many-body problem on a head of hair, producing an optimal combing strategy that balances trade-offs between comfort, efficiency and speed of combing in hair curls of varying geometrical and topological complexity.


Assuntos
Preparações para Cabelo , Cabelo
4.
Acta Biomater ; 142: 14-35, 2022 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-35202853

RESUMO

Hair care and treatment has evolved significantly through the years as new formulations are continuously being explored in an attempt to meet the demand in cosmetic and medicinal fields. While standard hair care procedures include hair washing, aimed at hair cleansing and maintenance, as well as hair dyeing and bleaching formulations for hair embellishment, modern hair treatments are mainly focused on circumventing hair loss conditions, strengthening hair follicle properties and treat hair infestations. In this regard, active compounds (ACs) included in hair cosmetic formulations include a vast array of hair cleansing and hair dye molecules, and typical hair treatments include anti-hair loss ACs (e.g. minoxidil and finasteride) and anti-lice ACs (e.g. permethrin). However, several challenges still persist, as conventional AC formulations exhibit sub-optimal performance and some may present toxicity issues, calling for an improved design of formulations regarding both efficacy and safety. More recently, nano-based strategies encompassing nanomaterials have emerged as promising tailored approaches to improve the performance of ACs incorporated into hair cosmetics and treatment formulations. The interest in using these nanomaterials is based on account of their ability to: (1) increase stability, safety and biocompatibility of ACs; (2) maximize hair affinity, contact and retention, acting as versatile biointerfaces; (3) enable the controlled release of ACs in both hair and scalp, serving as prolonged AC reservoirs; besides offering (4) hair follicle targeting features attending to the possibility of surface tunability. This review covers the breakthrough of nanomaterials for hair cosmetics and hair treatment, focusing on organic nanomaterials (polymer-based and lipid-based nanoparticles) and inorganic nanomaterials (nanosheets, nanotubes and inorganic nanoparticles), as well as their applications, highlighting their potential as innovative multifunctional nanomaterials towards maximized hair care and treatment. STATEMENT OF SIGNIFICANCE: This manuscript is focused on reviewing the nanotechnological strategies investigated for hair care and treatment so far. While conventional formulations exhibit sub-optimal performance and some may present toxicity issues, the selection of improved and suitable nanodelivery systems is of utmost relevance to ensure a proper active ingredient release in both hair and scalp, maximize hair affinity, contact and retention, and provide hair follicle targeting features, warranting stability, efficacy and safety. This innovative manuscript highlights the advantages of nanotechnology-based approaches, particularly as tunable and versatile biointerfaces, and their applications as innovative multifunctional nanomaterials towards maximized hair care and treatment.


Assuntos
Cosméticos , Preparações para Cabelo , Nanoestruturas , Cabelo , Preparações para Cabelo/farmacologia , Nanotecnologia
7.
Dermatitis ; 33(1): 91-102, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34149001

RESUMO

BACKGROUND: Hair care products (HCPs) may cause both allergic contact dermatitis (ACD) and irritant contact dermatitis (ICD). OBJECTIVES: The aims of the study were to determine the prevalence of HCP-associated ICD/ACD and to characterize relevant allergens. METHODS: This study is a retrospective analysis of North American Contact Dermatitis Group (NACDG) patch test data, 2001-2016. RESULTS: Of 38,775 patients tested, 3481 (9.0%) had positive patch test reactions associated with HCPs. The HCP-positive patients were significantly more likely to be female (79.9% vs 66.0%) and/or have primary sites of dermatitis on the face (32.0% vs 27.8%) or scalp (15.4% vs 2.2%) compared with the HCP-negative patients (P < 0.0001). Of 4908 HCP-associated positive patch test reactions, 86.9% (n = 4263) were due to allergens on the NACDG screening series; p-phenylenediamine (35.8%), methylisothiazolinone (9.7%), methylchloroisothiazolinone/methylisothiazolinone (8.7%), and cocamidopropyl betaine (5.9%) were the most frequent. Most reactions (87.7%, 3736/4263) were currently clinically relevant. The most common job associated with 366 occupationally related NACDG HCP-associated allergens was hairdresser/cosmetologist (71.9%). Two hundred eighty-two patients (0.7%) had ICD associated with HCPs. Shampoo/conditioners were the most frequent source of NACDG HCP-associated reactions (47.3%) and HCP-associated ICD (45.0%). CONCLUSIONS: Of the HCP-positive patients, 18.5% had HCP reactions to allergens not on the NACDG screening series, underscoring the importance of patch testing to expanded series in patients suspected of HCP allergy.


Assuntos
Alérgenos/efeitos adversos , Dermatite Alérgica de Contato/diagnóstico , Dermatite Ocupacional/diagnóstico por imagem , Preparações para Cabelo/efeitos adversos , Testes do Emplastro/métodos , Cosméticos/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Dermatite Ocupacional/etiologia , Feminino , Humanos , Masculino , América do Norte , Estudos Retrospectivos
8.
J Cosmet Dermatol ; 21(4): 1666-1674, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34085368

RESUMO

BACKGROUND: Synthetic shampoos have toxic chemical agents like chemicals such as parabens and sodium lauryl sulfate which damage the hair. To combat this issue, the use of natural herbal shampoos, as opposed to synthetic shampoos, is becoming increasingly popular. One of the many medicinal plants present in Karnataka and Kerala is Cyclea peltata. This plant has long been known to assist in wound healing, allergy relief, and hair and scalp improvement, as well as serving as a coolant for hair applications. OBJECTIVE: The key subject of this research was the preparation of plant extracts and fermentation of Cyclea peltata leaf extract with Lactobacillus plantarum, resulting in the formulation of an herbal shampoo. METHOD: The leaf extract contained alkaloids, flavonoids, tannins, phenolic acid, saponins, and proteins, according to previous research by this group. The fermented product showed the presence of lactic acid, which was a boon for shampoo base as it protects the hair from the sunlight and improves the texture and strength of hair fibers. Cyclea peltata was used as the main ingredient in herbal shampoo formulations, along with other herbal ingredients, and the formulated shampoo was characterized for its different organoleptic (Color, odor) and physicochemical properties (pH, solid content, wettability, emulsification, and foam stability) to find the best formulation. RESULT: Formulation H2 showed better organoleptic and physicochemical properties and thus was chosen as the best formulation among the 11 formulations. CONCLUSION: Formulation H2 is regarded as the best formulation based on the results of the physicochemical tests (Pleasant odor, pH 3.01, solid content of 5.75%, wettability of 1.68 s, and percentage emulsification of 68.75%).


Assuntos
Cyclea , Preparações para Cabelo , Cyclea/química , Preparações para Cabelo/química , Humanos , Índia , Extratos Vegetais , Sensação
9.
J Cosmet Dermatol ; 21(2): 827-835, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33834606

RESUMO

BACKGROUND: There is currently a great interest not only in developing products for the protection and recovery of chemically damaged hair, but also in developing effective protocols to investigate the impact of chemical treatments and attest the efficacy of innovative hair care products. Among the most relevant cosmetic treatments for hair are bleaching and coloring, which have been shown to significantly impair mechanical and structural properties. OBJECTIVES: This study aimed to characterize the damage induced by hair bleaching and coloring and to evaluate the protective effects of a hair care treatment based on integral silk proteins (fibroin and sericin) and vegetable-derived polysaccharides from linseed (Linum usitatissimum L.). METHODS: Hair swatches were subjected to different treatment protocols in order to evaluate the protective effect of proposed and benchmark products during bleaching and coloring processes. Tensile tests were performed to assess mechanical properties and improvement in resistance to breakage. Goniophotometric measurements were applied to determine improvement in luster. Hair fiber surface and relief were evaluated by SEM image analysis. RESULTS: Swatches bleached and treated with both evaluated products had a significant increase in resistance and reduced structural damage. Swatches colored and treated with both evaluated products showed reduced structural damage, and a significant increase in resistance and luster after the 1st and 5th washes. CONCLUSIONS: The proposed product was effective in protecting and repairing bleached and colored swatches, improving resistance and luster and reducing structural damage. By applying complementary techniques within a reliable evaluation protocol, it was possible to attest the protective properties of the product under study.


Assuntos
Cosméticos , Preparações para Cabelo , Cabelo , Humanos , Polissacarídeos/uso terapêutico , Proteínas
10.
Trends Biotechnol ; 40(5): 591-605, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-34666897

RESUMO

Cosmetics procedures and products combined with environmental insults and daily routines induce irreversible changes in hair. As result of damage, the hair loses some of its properties like strength, elasticity, and smoothness. Recent studies revealed the positive effects of protein-based cosmetics in providing protection to hair. Additionally, these cosmetic products have also shown a great ability to modify hair fibers. We review the effect of protein-based cosmetic formulations on hair properties like color, scent, strength, shape, and volume, highlighting the potential of keratin-based particles and keratin-fusion proteins. In the future, incorporating multifunctional proteins and peptides in the development of alternative hair formulations will result in advanced, sustainable, ecofriendly cosmetic products with a great impact on the cosmetic industry.


Assuntos
Cosméticos , Preparações para Cabelo , Biotecnologia , Queratinas/química , Queratinas/metabolismo , Peptídeos
11.
Se Pu ; 40(4): 343-353, 2022 Apr.
Artigo em Chinês | MEDLINE | ID: mdl-35362682

RESUMO

Cosmetic products for hair loss prevention are often mixed with prohibited substances such as hormones, antibiotics, and forbidden pharmacologically active substances. Although drugs increase the efficacy of cosmetic products, they cause skin irritation and allergic reactions, upon long-term exposure. Given the increasing number of hair loss prevention cosmetics on the market, the need to guarantee product safety calls for efficient and reliable methods to identify illegal ingredients in these products. Chromatography combined with high-resolution mass spectrometry offers the advantages of high resolution and high throughout, thus being a powerful technique for simultaneously detecting illegal ingredients in cosmetics. In this study, an ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry (UPLC-Q-TOF-MS) method for detecting 19 illegal chemical components was established. Combined with the scientific database, a screening platform for hair loss prevention cosmetics was constructed. The effect of extraction solvent was investigated. The chromatographic and mass spectrometry conditions were optimized. Under the optimal conditions, separation was achieved within 20 min on an ACQUITY UPLC BEH C18 column (100 mm×2.1 mm, 1.7 µm). Acetonitrile and 2 mmol/L ammonium formate solution containing 0.05% formic acid were used as mobile phases for gradient elution. The 19 compounds were detected by positive ion electrospray ionization (ESI) in the MSE mode. The chromatographic retention time, precursor ions, product ions of the target analytes, and abundance ratio were collected to construct a screening database with UNIFI software. The 19 compounds were well separated, with good linearity. The limits of detection (LODs) and limits of quantification (LOQs) were 0.025-0.05 µg/g and 0.075-0.15 µg/g, respectively. Hair lotion and shampoo, which are commonly marketed as hair loss prevention cosmetics, were selected as the respective matrices for the recovery experiment. The average recoveries of the 19 compounds ranged from 68.6% to 118.6%, and the relative standard deviations (RSDs) were 0.3%-10.3%. Then, 77 batches of cosmetic samples were detected and screened under the same conditions. The TOF-MS information, including the retention time, ion addition mode, mass-to-charge ratio of the parent ions and fragment ions, as well as the abundance ratio, were compared between the cosmetic samples and the standard MS information with UNIFI software. Finally, two batches of samples that were illegally adulterated with minoxidil and finasteride were identified. The ESI fragmentation pathway of the product ions from minoxidil was also proposed. The matrix matching external standard method was used to determine the amounts of minoxidil and finasteride in the two batches of hair lotion, and they were as high as 60 mg/g and 0.31 mg/g, respectively. This result revealed that multiple chemical components were simultaneously added to hair loss prevention cosmetics. Furthermore, the amount of the illegally added drug was very high, indicating high safety risk for consumers using such cosmetics. The present method has the advantages of simple operation, high sensitivity, and good reproducibility. It can be used for rapid screening and simultaneous quantitative analysis of various illegal chemicals in hair loss prevention cosmetics.


Assuntos
Cosméticos , Preparações para Cabelo , Alopecia/prevenção & controle , Cromatografia Líquida de Alta Pressão , Cromatografia Líquida , Cosméticos/análise , Humanos , Reprodutibilidade dos Testes , Espectrometria de Massas em Tandem
13.
Bull Cancer ; 108(11): 1030-1035, 2021 Nov.
Artigo em Francês | MEDLINE | ID: mdl-34579943

RESUMO

INTRODUCTION: Socio-aesthetics is the delivery appropriate beauty care in a population weakened by a physical, psychological and/or social attack. It has found its place in indications in both medical (especially in oncology) and social settings. It offers many types of treatments including facials, foot beauty, make-up, wig tips, body massage, product advice, cosmetic manicure, varnishing… The main purpose of this study was to evaluate pain reduction as a result of socio-aesthetics. METHODS: One hundred and eighty patients were offered a socio-aesthetic session between 12/01/2018 and 11/30/2019. One hundred and fifty-seven (87,2%) accepted the care (56.7% of women/43.3% of men, regardless of the type of cancer) and all agreed to complete a questionnaire on the type of treatment received, the benefits felt and a Likert pain assessment scale before and after the treatment. RESULTS: No patient experienced an increase in pain after the socio-aesthetic care. In the general population, the mean pain evaluation was rated at 1.31/10 and 0.78/10 before and after the session respectively, p<10-5. By selecting patients experiencing pain before treatment (40 patients, 28.0% of the total population), the mean pain evaluation was 4.27/10 and 2.52/10 before and after the treatment respectively, p<10-5. Pain was significantly reduced by massage. No patient found the socio-aesthetic treatment unnecessary. CONCLUSION: Socio-aesthetics is definitely a supportive care in oncology as it is significantly analgesic. It is easily accepted by men and regardless of the type of cancer. Researchers should conduct more studies on its impact on the quality of life.


Assuntos
Indústria da Beleza/métodos , Dor do Câncer/terapia , Cosméticos/uso terapêutico , Higiene da Pele/métodos , Idoso , Aconselhamento , Feminino , Preparações para Cabelo/uso terapêutico , Humanos , Masculino , Massagem , Unhas , Neoplasias/terapia , Medição da Dor/estatística & dados numéricos , Fatores Sexuais
14.
Cutis ; 108(1): 20-22, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34397353

RESUMO

Traction alopecia (TA) remains a common concern for Black women visiting a dermatologist. Understanding cultural hair care practices, timely diagnosis, and discontinuation of high-risk hairstyles are essential for preventing TA from progressing to scarring alopecia. This dialogue might be difficult for hair-discordant physicians and patients because of a lack of training and shared experiences. We present an empathetic and culturally sensitive method for discussing TA with patients.


Assuntos
Preparações para Cabelo , Tração , Afro-Americanos , Alopecia/diagnóstico , Aconselhamento , Feminino , Humanos
15.
Int J Cosmet Sci ; 43 Suppl 1: S26-S33, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34424549

RESUMO

OBJECTIVE: Increasing scalp hair fullness is a global unmet consumer need. An approach to decrease hair shedding by reducing scalp stratum corneum oxidation via a combination of antioxidant and barrier-enhancing technologies has been previously demonstrated. The purpose of this study was to test the effectiveness of the individual antioxidant piroctone olamine in two different product forms (shampoo or leave-on product) for activity to improve hair retention. METHODS: Female subjects with self-perceived hair thinning participated in an 8-week, double-blind, placebo-controlled, randomized clinical study to evaluate either a piroctone olamine (PO) containing shampoo or a PO containing leave on treatment, each relative to their corresponding placebo formulation Too many periods. Results for phototrichograms, TEWL, and biomarker analysis of scalp condition for the shampoo treatments are discussed. Phototrichogram results are shared for the assessment of the leave on treatment. RESULTS: Statistically significant increases in hair amount were observed by phototrichogram after use of both PO-containing products versus placebo formulations. The PO shampoo treatment also significantly decreased oxidative stress on the hair and scalp, and improved scalp condition as assessed by TEWL and scalp biomarker values. CONCLUSION: These results illustrate the effectiveness of a cosmetic antioxidant to improve scalp condition thereby improving hair retention. The observed improvements in scalp condition are consistent with previous reports with other antioxidant technologies and suggest that the hair retention effect was achieved by preventing oxidative damage to the scalp.


Assuntos
Alopecia/tratamento farmacológico , Antioxidantes/uso terapêutico , Etanolaminas/uso terapêutico , Preparações para Cabelo/uso terapêutico , Piridonas/uso terapêutico , Couro Cabeludo/efeitos dos fármacos , Administração Tópica , Adulto , Idoso , Antioxidantes/administração & dosagem , Método Duplo-Cego , Combinação de Medicamentos , Etanolaminas/administração & dosagem , Feminino , Preparações para Cabelo/administração & dosagem , Humanos , Pessoa de Meia-Idade , Piridonas/administração & dosagem
16.
Int J Cosmet Sci ; 43 Suppl 1: S14-S25, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34424558

RESUMO

OBJECTIVE: Increasing hair fullness is a global unmet need for many men and women. An approach to the problem is to decrease hair fall or shedding by reducing scalp stratum corneum oxidation and barrier damage to increase hair retention. This study evaluated a combination of functional antioxidants and barrier-enhancing cosmetic ingredients to improve scalp condition thereby enabling stronger hair anchorage and longer retention. METHODS: Male and female subjects with normal scalp condition and self-perceived hair thinning participated in a 24-week, double-blind, placebo-controlled, randomized clinical study assessing either a regimen of treatment shampoo and leave-on treatment containing functional antioxidant and barrier-enhancing agents or an identical placebo chassis shampoo control. The functional ingredients were piroctone olamine, zinc pyrithione, zinc carbonate, niacinamide, panthenol and caffeine. At baseline and after 8, 16 and 24 weeks of product use, several measurements were taken: hair shedding, total hair count (by phototrichogram), hair samples, TEWL and evaluation of biomarkers of scalp and hair conditions. Subjects also completed self-assessment questionnaires. RESULTS: Statistically significant effects for functional ingredient-containing treatment regimen versus a placebo control shampoo formulation were observed for reduced hair shedding, increased total hair count, reduced TEWL and improvement in scalp biomarker values. Subjects also noticed these improvements assessed via self-assessment questionnaires. CONCLUSIONS: These results establish that the use of functional antioxidant and barrier-enhancing agents to further improve scalp condition can enable a reduction in hair shedding and thus an increase in perceived hair fullness. The underlying improvements in scalp condition suggest the hair benefits were achieved as a result of improved scalp skin barrier and scalp condition leading to a viable preventative approach for hair thinning.


Assuntos
Alopecia/tratamento farmacológico , Antioxidantes/uso terapêutico , Preparações para Cabelo/uso terapêutico , Couro Cabeludo/efeitos dos fármacos , Administração Tópica , Adulto , Idoso , Antioxidantes/administração & dosagem , Biomarcadores/sangue , Método Duplo-Cego , Preparações para Cabelo/administração & dosagem , Humanos , Masculino , Pessoa de Meia-Idade
17.
J Dtsch Dermatol Ges ; 19(12): 1729-1734, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34427043

RESUMO

Hair cosmetics such as shampoos, hair dyes, bleaching agents or hair straightening creams contain frequent contact allergens. These can lead to allergic contact dermatitis especially in hairdressers, but also in their customers and in others who use hair products at home. While hairdressers suffer mainly from hand dermatitis, in customers and home-users, dermatitis primarily affects the head, neck and face. In this mini-review, we propose a diagnostic algorithm in two steps, based on patch testing, that can be used for the assessment of suspected hair product-induced contact dermatitis. In a first step, we recommend testing the German Contact Allergy Group (DKG) standard series, DKG ointment series, DKG preservative series, DKG hairdresser series, DKG fragrance series as well as (especially in hairdressers) the DKG rubber series. In a second step, if the culprit allergen cannot be identified with the help of the standardized test series and there is a well-founded suspicion, testing the patient's own products, such as shampoos, hair sprays and hair dyes, is recommended.


Assuntos
Cosméticos , Dermatite Alérgica de Contato , Tinturas para Cabelo , Preparações para Cabelo , Alérgenos/efeitos adversos , Cosméticos/efeitos adversos , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/etiologia , Tinturas para Cabelo/efeitos adversos , Preparações para Cabelo/efeitos adversos , Humanos , Testes do Emplastro
19.
Environ Health ; 20(1): 86, 2021 07 28.
Artigo em Inglês | MEDLINE | ID: mdl-34320990

RESUMO

BACKGROUND: Prenatal endocrine disrupting chemical (EDC) exposure has been associated with increased risk of preterm birth. Non-Hispanic Black women have higher incidence of preterm birth compared to other racial/ethnic groups and may be disproportionately exposed to EDCs through EDC-containing hair products. However, research on the use of EDC-associated hair products during pregnancy and risk of preterm birth is lacking. Therefore, the objective of this pilot study was to estimate associations of prenatal hair product use with gestational age at delivery in a Boston, Massachusetts area pregnancy cohort. METHODS: The study population consisted of a subset of participants enrolled in the Environmental Reproductive and Glucose Outcomes (ERGO) Study between 2018 and 2020. We collected self-reported data on demographics and hair product use using a previously validated questionnaire at four prenatal visits (median: 12, 19, 26, 36 weeks' gestation) and abstracted gestational age at delivery from medical records. We compared gestational age and hair product use by race/ethnicity and used linear regression to estimate covariate-adjusted associations of product use and frequency of use at each study visit with gestational age at delivery. Primary models were adjusted for maternal age at enrollment and delivery method. RESULTS: Of the 154 study participants, 7% delivered preterm. Non-Hispanic Black participants had lower mean gestational age at delivery compared to non-Hispanic White participants (38.2 vs. 39.2 weeks) and were more likely to report ever and more frequent use of hair products. In regression models, participants reporting daily use of hair oils at visit 4 had lower mean gestational age at delivery compared to non-users (ß: -8.3 days; 95% confidence interval: -14.9, -1.6). We did not find evidence of associations at earlier visits or with other products. CONCLUSIONS: Frequent use of hair oils during late pregnancy may be associated with shorter gestational duration. As hair oils are more commonly used by non-Hispanic Black women and represent potentially modifiable EDC exposure sources, this may have important implications for the known racial disparity in preterm birth.


Assuntos
Disruptores Endócrinos , Preparações para Cabelo , Óleos , Nascimento Prematuro/epidemiologia , Adulto , Boston/epidemiologia , Estudos de Coortes , Feminino , Idade Gestacional , Humanos , Pessoa de Meia-Idade , Projetos Piloto , Gravidez , Nascimento Prematuro/etnologia , Adulto Jovem
20.
Int J Cosmet Sci ; 43(4): 446-457, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34080204

RESUMO

BACKGROUND: Different hair types respond differently to cosmetic treatments; hence, many options ought to be availed to the consumer. The purpose of this study was to evaluate the use of antioxidant extract from Dicerocaryum senecioides as active alternatives in hair semi-permanent waving and hair conditioning. METHODS: The antioxidant phytochemicals were first identified and isolated by thin-layer chromatography (TLC) and spraying with revealing agents. The antioxidant potency was determined by DPPH antiradical scavenging and ferric reducing power methods. The extract was incorporated in two different formulations to make the extract perm (bio-semi-permanent) and the antioxidant hair conditioner (AC). The formulations had their performance examined for hair curling and conditioning on Asian and African hair types. Hair damage was assessed by scanning the surface of treated samples on an attenuated total reflectance-Fourier transform infrared spectrometer (ATR-FTIR) and by quantifying lost protein on ultraviolet visible (UV-Vis) spectrophotometer. RESULTS: The extract antioxidant had an IC50 of 26.54 ± 0.34 µg/ml exhibiting greater antioxidant potency compared to the controls quercetin (38.84 ± 0.12 µg/ml) and ascorbic acid (35.22 ± 0.07 µg/ml). The extract perm had a lower curling ability indicated by a perm set of 85.10 ± 3.92% and 81.35 ± 2.35% for Asian and African hairs, respectively, while commercial product, ammonium thioglycolate (ATG) had 96.05 ± 1.70% and 93.60 ± 2.21% for the same. The curling of hair with extract perm resulted in less oxidative damage with oxidative peak areas of 3.37 ± 0.09 and 3.71 ± 0.03 as well as lower protein losses of 4.72 ± 0.71 µg/mg and 5.62 ± 0.70 µg/mg on Asian and African hair samples, respectively. The application of AC reduced the oxidative damage peak areas of ATG and extract perm treated Asian hair samples by 1.15 and 0.48 units, respectively. AC was also effective in reducing damage caused by UV radiation on ATG-treated samples by 1.06 units (African hair) and 1.09 units on Asian hair. CONCLUSION: The results show antioxidant extracts from Dicerocryum senecioides as a promising and safer alternative for hair conditioning and semi-permanent curling.


CONTEXTE: les réactions aux traitements cosmétiques varient d'un type de cheveux à l'autre. Ainsi, de nombreuses options doivent être mises à disposition des consommateurs. Cette étude avait pour objectif d'évaluer l'utilisation d'un extrait antioxydant de Dicerocaryum senecioides en vue de proposer de nouveaux choix de produits actifs pour les mises en plis semi-permanentes et le conditionnement capillaire. MÉTHODES: les agents phytochimiques antioxydants ont d'abord été identifiés et isolés par chromatographie sur couche mince (CCM) et par pulvérisation d'agents révélateurs. La puissance antioxydante a été déterminée par une méthode de piégeage antiradicalaire à l'aide du DPPH et par un procédé de puissance de réduction du fer. L'extrait a été incorporé dans deux formulations différentes pour obtenir la permanente (semi-permanentes biologiques) et l'après-shampooing capillaire antioxydant. Les performances des formulations ont été évaluées selon des critères de bouclage et conditionnement capillaires sur des cheveux de types asiatiques et africains. L'évaluation des lésions capillaires reposait sur un examen de la surface des échantillons traités à l'aide d'un spectromètre infrarouge à transformée de Fourier en réflectance totale atténuée (attenuated total reflectance Fourier transform infra-red spectrometer, ATR-FTIR) et sur une quantification des protéines perdues à l'aide d'un spectrophotomètre à ultraviolet visible (UV-Vis). RÉSULTATS: l'extrait antioxydant présentait une concentration inhibitrice médiane (IC50 ) de 26.54 ± 0.34 µg/ml, d'où une plus grande puissance antioxydante par rapport aux produits témoins, à savoir la quercétine (38.84 ± 0.12 µg/ml) et l'acide ascorbique (35.22 ± 0.07 µg/ml). La permanente présentait une plus faible capacité de bouclage, révélée par un taux de fixation de la permanente de 85.10 ± 3.92 % et de 81.35 ± 2.35 % pour les cheveux asiatiques et africains respectivement, tandis que le produit disponible dans le commerce, à savoir le thioglycolate d'ammonium (ATG), donnait des taux de 96.05 ± 1.70 % et de 93.60 ± 2.21 % dans les mêmes conditions. Le bouclage des cheveux à l'aide de la permanente a entraîné moins de lésions oxydatives, avec des zones de pics d'oxydation de 3.37 ± 0.09 et de 3.71 ± 0.03, ainsi que des pertes protéiques plus faibles, de 4.72 ± 0.71 µg/mg et de 5.62 ± 0.70 µg/mg sur les échantillons de cheveux asiatiques et africains respectivement. L'application de l'après-shampooing antioxydant a permis de réduire de 1.15 unité les zones de pics d'oxydation due à l'ATG sur les échantillons de cheveux asiatiques et la permanente a permis de traiter ces mêmes échantillons à raison de 0.48 unité. L'après-shampooing antioxydant s'est également avéré efficace pour réduire les lésions causées par les rayons UV sur les échantillons traités par ATG, de 1.06 unité sur les cheveux africains et de 1.09 unité sur les cheveux asiatiques. CONCLUSION: les résultats montrent que les extraits antioxydants de Dicerocaryum senecioides constituent une option prometteuse et plus sûre pour le conditionnement capillaire et les mises en pli semi-permanentes.


Assuntos
Antioxidantes/farmacologia , Preparações para Cabelo/química , Pedaliaceae/química , Extratos Vegetais/farmacologia , Cabelo/efeitos da radiação , Humanos , Estresse Oxidativo/efeitos dos fármacos , Espectroscopia de Infravermelho com Transformada de Fourier/métodos , Raios Ultravioleta
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