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1.
Invest Ophthalmol Vis Sci ; 63(10): 10, 2022 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-36107112

RESUMO

Purpose: To assess the longitudinal changes in crystalline lens in persistent non-myopic and myopic children. Methods: Four cohorts of children were recruited from Guangzhou, China, from first year of kindergarten (G0, n = 1129), first year of primary school (G1, n = 1324), fourth year of primary school (G4, n = 1854), and first year of junior high school (G7, n = 867) in 2018 and followed up annually for 2 years. All children received cycloplegic autorefraction and ocular biometry measurement. Children were classified into categories of persistent non-myopia (PNM; spherical equivalent refraction [SER] ≥-0.5 diopter [D] at baseline and during follow-up), persistent myopia (PM; SER <-0.5 D at baseline and during follow-up), or newly developed myopia (NDM: SER ≥-0.5 D at baseline and <-0.5 D during follow-up). Results: The mean (SD) age was 3.69 (0.34) years for children in G0, 6.79 (0.35) years in G1, 9.52 (0.42) years in G4, and 12.56 (0.38) years in G7. A LOWESS plot showed a three-stage pattern of change in lens thickness (LT) in PNM children including a rapid decrease from 3 to 7 years of age and a slower decrease from 7 to 11 years, followed by an increase thereafter. Similar trends were observed in the PM and NDM groups, although there was less change in LT. In contrast, lens power (LP) decreased consistently in all cohorts during the follow-up. No significant changes in LT or LP were observed around myopia onset. Conclusions: The lens showed a three-stage pattern of change in LT, whereas there was continuous loss of LP in children ages 3 to 15 years.


Assuntos
Cristalino , Miopia , Adolescente , Biometria , Criança , Pré-Escolar , Humanos , Midriáticos , Miopia/diagnóstico , Refração Ocular
2.
J Int Med Res ; 50(9): 3000605221123667, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36112803

RESUMO

We describe a technique for metallic intralenticular foreign body (ILFB) removal in a patient in whom there was no or minimal cataract formation or other complications. This technique required creating two corneal small incisions around the ILFB for inserting iris retractors to expose the ILFB. At the foreign body position, a clear corneal incision was made, and then the ILFB was removed with minimal manipulation by an intraocular magnet without complications. Because most occupational traumas occur in young people, this technique avoids the adverse outcomes of lens extraction in this age group.


Assuntos
Extração de Catarata , Catarata , Corpos Estranhos no Olho , Cristalino , Adolescente , Extração de Catarata/efeitos adversos , Corpos Estranhos no Olho/complicações , Corpos Estranhos no Olho/cirurgia , Humanos , Implante de Lente Intraocular/efeitos adversos , Cristalino/cirurgia
3.
J Radiol Prot ; 42(3)2022 Sep 19.
Artigo em Inglês | MEDLINE | ID: mdl-36070675

RESUMO

For planned occupational exposure situations, the International Commission on Radiological Protection (ICRP) publication 118 recommends an equivalent dose limit for the lens of the eye of 20 mSv yr-1averaged over 5 yr with no single year exceeding 50 mSv. Regulatory authorities of various jurisdictions worldwide followed some or all, of the ICRP recommendations and implemented reduced occupational lens of eye dose limits in their legislation. As compliance with the eye-lens dose limit will be based on the summation of doses received from all types of radiation, applicable to a variety of workplaces, the contribution of neutrons to eye lens dose will be important where it contributes a significant fraction of the total dose to the eye lens. This work presents and discusses computed personal absorbed dose (Dlens/Φ), and personal dose equivalent (Hp(3)/Φ) as well as a newly proposed relative biological effectiveness (RBE)-weighted absorbed dose (RBE ×Dlens/Φ) conversion coefficients for the lens of the eye for neutron exposure at incident energies from thermal to ∼20 MeV. TheDlens/Φ coefficients were obtained from a simulation model developed for this study that contains the stylised eye model embedded in the adult UF-ORNL mathematical phantom. The modelling techniques used in these simulations were also used to calculateHp(3)/Φ for the International Commission on Radiation Units and Measurements (ICRU) slab and cylinder phantoms. All simulations carried out for this study utilised the Monte Carlo N-Particle (MCNP) series of codes. The results are compared with the related published data. The issue of compliance with the current equivalent dose limit for the lens of the eye is addressed from a neutron perspective considering the recent proposed redefinition of the operational quantities for external radiation exposure in ICRU report 95. The use of a radiation weighted absorbed dose (RBE ×Dlens, in Gy) is proposed for the tissue reactions in the eye-lens for neutron radiation as per the National Council on Radiation Protection and Measurements report 180, and in line with the recent review and revision of the System of Radiological Protection To Keeping the ICRP Recommendations Fit for Purpose, which states that RBE weighted dose should be used for high-Linear energy transfer (LET) radiations such as neutrons. This confirms the earlier statement in ICRP publication 92, paragraph 297 and reiterated in the Executive summary, paragraph (q) of ICRP publication 118. The proposed approach would provide an operational quantity consistent with the units of the new eye-lens dose limits without being overly conservative.


Assuntos
Cristalino , Proteção Radiológica , Método de Monte Carlo , Nêutrons , Doses de Radiação , Proteção Radiológica/métodos , Radiometria/métodos
4.
Invest Ophthalmol Vis Sci ; 63(10): 1, 2022 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-36048019

RESUMO

Purpose: The malfunction of junctional adhesion molecule C (JAM-C) has been reported to induce congenital cataract in humans and mice; however, specific characters and the mechanism of this cataract are still unclear. This study aimed to characterize abnormal lens development in Jamc knockout mice and clarify the underlying mechanism. Methods: Jamc knockout mice backcrossed onto the C57BL/6 genetic background were used for this research. Slit-lamp and darkfield images showed the cataract phenotype of Jamc-/- mice. Hematoxylin and eosin staining was performed to visualize the morphological and histological features. RNA sequencing was applied to detect differentially expressed genes. Quantitative RT-PCR, western blot, and immunofluorescence were used to determine the level of unfolded protein response (UPR)-related genes. TUNEL staining was utilized to label cell death. Results: Jamc knockout mice exhibited nuclear cataract with abnormal lens morphology and defective degradation of nuclei and organelles in lens fiber cells. Compared with wild-type control mice, the expression level of BiP, CHOP, TRIB3, and CHAC1, genes involved in endoplasmic reticulum stress and the UPR, were highly upregulated in Jamc-/- lenses, suggesting that abnormal lens development was accompanied by UPR activation. Moreover, increased cell death was also found in Jamc-/- lenses. Conclusions: Congenital nuclear cataract caused by Jamc deficiency is accompanied by defective degradation of nuclei and organelles in lens fiber cells, lens structure disorder, and UPR activation, suggesting that JAM-C is required for maintaining normal lens development and that UPR activation is involved in cataract formation in Jamc-deficient lenses.


Assuntos
Catarata , Cristalino , Animais , Catarata/metabolismo , Humanos , Cristalino/metabolismo , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Knockout , Resposta a Proteínas não Dobradas
5.
Transl Vis Sci Technol ; 11(9): 5, 2022 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-36069859

RESUMO

Purpose: To ascertain the theoretical impact of anatomical variations in the effective lens position (ELP) of the intraocular lens (IOL) in a thick lens eye model. The impact of optimization of IOL power formulas based on a single lens constant was also simulated. Methods: A schematic eye model was designed and manipulated to reflect changes in the ELP while keeping the optical design of the IOL unchanged. Corresponding relationships among variations in ELP, postoperative spherical equivalent refraction, and required IOL power adjustment to attain target refractions were computed for differing corneal powers (38 diopters [D], 43 D, and 48 D) with IOL power ranging from 1 to 35 D. Results: The change in ELP required to compensate for various systematic biases increased dramatically with low-power IOLs (less than 10 D) and was proportional to the magnitude of the change in refraction. The theoretical impact of the variation in ELP on postoperative refraction was nonlinear and highly dependent on the optical power of the IOL. The concomitant variations in IOL power and refraction at the spectacle plane, induced by varying the ELP, were linearly related. The influence of the corneal power was minimal. Conclusions: The consequences of variations in the lens constant mainly concern eyes receiving high-power IOLs. The compensation of a systematic bias by a constant increment of the ELP may induce a nonsystematic modification of the predicted IOL power, according to the biometric characteristics of the eyes studied. Translational Relevance: Optimizing IOL power formulas by altering the ELP may induce nonsystematic modification of the predicted IOL power.


Assuntos
Cristalino , Lentes Intraoculares , Biometria , Córnea/cirurgia , Refração Ocular
6.
Artigo em Inglês | MEDLINE | ID: mdl-36012010

RESUMO

Cataracts are one of the most common causes of effective vision loss. Although most cases of cataracts are related to the ageing process, identifying modifiable risk factors can prevent their onset or progression. Many studies have suggested that micro and macroelement levels, not only in blood serum but also in the lens and aqueous humour, may affect the risk of the occurrence and severity of cataracts. This systematic review aims to summarise existing scientific reports concerning the importance of trace elements in cataractogenesis. Many authors have pointed out elevated or decreased levels of particular elements in distinct ocular compartments. However, it is not known if these alterations directly affect the increased risk of cataract occurrence. Further studies are needed to show whether changes in the levels of these elements are correlated with cataract severity and type. Such information would be useful for determining specific recommendations for micronutrient supplementation in preventing cataractogenesis.


Assuntos
Catarata , Cristalino , Oligoelementos , Humor Aquoso , Catarata/epidemiologia , Olho , Humanos
7.
J Radiol Prot ; 42(3)2022 Sep 19.
Artigo em Inglês | MEDLINE | ID: mdl-35940135

RESUMO

Estimation of effective dose and dose to the lens of the eye for workers involved in interventional procedures is challenging. The interventional procedures in question involve high doses and, due to this, workers need to wear protective garments. As a result, various methodologies have been developed to assess the effective dose and dose to the lens of the eye. In the present study, measurements from four European dosimetry services, over and under protective garments, have been collected and analysed in order to provide practical guidelines based on the routine use of personal dosemeters from staff in interventional workplaces. The advantages and limitations of using one or two dosemeters are discussed.


Assuntos
Cristalino , Exposição Ocupacional , Monitoramento de Radiação , Proteção Radiológica , Humanos , Exposição Ocupacional/análise , Exposição Ocupacional/prevenção & controle , Doses de Radiação , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Radiologia Intervencionista/métodos
9.
Artigo em Inglês | MEDLINE | ID: mdl-35954967

RESUMO

Exposure to green spaces contributes to residents' physical and mental health and well-being. The equitable allocation of green space has also become an increasingly important issue for society and the government. This study takes 3281 communities in Shenzhen as the analysis units. Using web crawlers, semantic segmentation based on deep learning, web map path planning and entropy weighting methods, four types of residents' daily green exposure indicators are calculated, including community green space ratio, green view index (GVI), park accessibility, and the weighted composite green exposure index. The results reveal inequalities in the level of green exposure in Shenzhen's communities across economic classes, mainly in GVI and comprehensive green exposure. We also found that the level of composite green exposure is relatively stable; however, green space ratio attainment levels for newer communities are increasing and GVI and park accessibility attainment levels are decreasing. Finally, among the newly built communities: compared to the low-income level communities, the high-income level communities have a significant advantage in green space, but the mid-income level communities do not have such an advantage. The main findings of this study can provide policy implications for urban green space planning, including the need to prioritize the addition of public green space near older communities with poor levels of green exposure, the addition of street greenery near communities with poor levels of composite green exposure, and ensuring that parks have entrances in all four directions as far as possible.


Assuntos
Cristalino , Parques Recreativos , Cidades , Planejamento de Cidades , Meio Ambiente
10.
J Vis ; 22(9): 4, 2022 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-35925580

RESUMO

Ocular accommodation is the process of adjusting the eye's crystalline lens so as to bring the retinal image into sharp focus. The major stimulus to accommodation is therefore retinal defocus, and in essence, the job of accommodative control is to send a signal to the ciliary muscle which will minimize the magnitude of defocus. In this article, we first provide a tutorial introduction to control theory to aid vision scientists without this background. We then present a unified model of accommodative control that explains properties of the accommodative response for a wide range of accommodative stimuli. Following previous work, we conclude that most aspects of accommodation are well explained by dual integral control, with a "fast" or "phasic" integrator enabling response to rapid changes in demand, which hands over control to a "slow" or "tonic" integrator which maintains the response to steady demand. Control is complicated by the sensorimotor latencies within the system, which delay both information about defocus and the accommodation changes made in response, and by the sluggish response of the motor plant. These can be overcome by incorporating a Smith predictor, whereby the system predicts the delayed sensory consequences of its own motor actions. For the first time, we show that critically-damped dual integral control with a Smith predictor accounts for adaptation effects as well as for the gain and phase for sinusoidal oscillations in demand. In addition, we propose a novel proportional-control signal to account for the power spectrum of accommodative microfluctuations during steady fixation, which may be important in hunting for optimal focus, and for the nonlinear resonance observed for low-amplitude, high-frequency input. Complete Matlab/Simulink code implementing the model is provided at https://doi.org/10.25405/data.ncl.14945550.


Assuntos
Acomodação Ocular , Cristalino , Humanos
12.
Int J Mol Sci ; 23(16)2022 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-36012695

RESUMO

Cataract is the leading cause of blindness worldwide. A diverse range of medication has been invented to prevent or treat cataract. Pirenoxine (PRX), a drug with strong antioxidant properties, has been used topically to treat cataract, and there is much evidence to demonstrate the beneficial effects of PRX on lens opacity from in vitro and in vivo models. In clinical use, PRX has been prescribed worldwide by ophthalmologists for over six decades; however, there is still controversy with regard to its efficacy, and thus PRX remains an off-label use for cataract treatment. This comprehensive review summarizes and discusses evidence pertinent to the mechanisms of PRX and its efficacy mainly on cataract models. The issues that have been deemed uncertain over the six-decade use of PRX are examined. The information summarized in this review should provide insights into contriving novel approaches for the treatment of cataract.


Assuntos
Catarata , Cristalino , Antioxidantes/farmacologia , Antioxidantes/uso terapêutico , Catarata/tratamento farmacológico , Catarata/etiologia , Catarata/prevenção & controle , Humanos , Oxazinas/farmacologia
13.
Aging (Albany NY) ; 14(15): 6128-6148, 2022 Aug 10.
Artigo em Inglês | MEDLINE | ID: mdl-35951367

RESUMO

The male abnormal gene family 21 (mab21), was initially identified in C. elegans. Since its identification, studies from different groups have shown that it regulates development of ocular tissues, brain, heart and liver. However, its functional mechanism remains largely unknown. Here, we demonstrate that Mab21L1 promotes survival of lens epithelial cells. Mechanistically, Mab21L1 upregulates expression of αB-crystallin. Moreover, our results show that αB-crystallin prevents stress-induced phosphorylation of p53 at S-20 and S-37 through abrogating the activation of the upstream kinases, ATR and CHK1. As a result of suppressing p53 activity by αB-crystallin, Mab21L1 downregulates expression of Bak but upregulates Mcl-1 during stress insult. Taken together, our results demonstrate that Mab21L1 promotes survival of lens epithelial cells through upregulation of αB-crystallin to suppress ATR/CHK1/p53 pathway.


Assuntos
Cristalinas , Cristalino , Animais , Caenorhabditis elegans/metabolismo , Cristalinas/genética , Células Epiteliais/metabolismo , Cristalino/metabolismo , Masculino , Proteína Supressora de Tumor p53/genética , Proteína Supressora de Tumor p53/metabolismo
14.
Transl Vis Sci Technol ; 11(8): 21, 2022 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-35994266

RESUMO

Purpose: To develop a zebrafish cataract model for screening potential anti-cataract compounds. Methods: Living zebrafish were anesthetized and exposed to ultraviolet-C (UV-C) irradiation at a dosage of 3250 mJ/cm2/d until they developed severe cataracts. These cataracts were graded based on photographs analyzed with ImageQuant TL version 7.0. Fish with severe cataracts were used to evaluate a range of compounds for cataract treatment, including the previously demonstrated hit compound lanosterol. For the initial evaluation, fish were divided into four groups: no treatment, balanced salt solution, ß-cyclodextrin (ß-CD), and lanosterol dissolved in ß-CD. The treatments were performed for 10 days, and the clarity of lenses was evaluated. To assess the persistence of treatment, fish were treated with ß-CD and lanosterol dissolved in ß-CD for seven consecutive days followed by monitoring for three days without treatment. Results: The average time for zebrafish to develop severe cataracts using the present UV-C irradiation protocol was 7.8 days (range 4-15 days). Both study designs required only another 10 days to determine the effect of hit compounds. The total experimental period could be completed within one month, and the entire experiment was economical. Conclusions: We could assay a large number of hit compounds at a reasonable cost and within a short time using this newly developed zebrafish cataract model. These assays may allow development of an efficient platform for screening potential anti-cataract compounds. Translational Relevance: The results may facilitate the development of ani-cataract medication for humans after further experiments and investigations.


Assuntos
Catarata , Cristalino , Animais , Catarata/tratamento farmacológico , Modelos Animais de Doenças , Humanos , Lanosterol/farmacologia , Lanosterol/uso terapêutico , Cristalino/efeitos da radiação , Peixe-Zebra
15.
Vestn Oftalmol ; 138(4): 117-125, 2022.
Artigo em Russo | MEDLINE | ID: mdl-36004600

RESUMO

The article reviews the findings on the anatomy, morphological and biomechanical features of the accommodation apparatus. Modern methods of imaging and biometry confirm the validity of the Helmholtz lenticular theory of accommodation, according to which its mechanism involves three main components: the ciliary body, the zonular fibres and the lens capsule, the lens itself. Based on this, there is certain interest in studying the degree of participation of each of these components in the development of age-related changes in accommodation (presbyopia).


Assuntos
Cápsula do Cristalino , Cristalino , Presbiopia , Acomodação Ocular , Envelhecimento , Corpo Ciliar/diagnóstico por imagem , Humanos , Cristalino/diagnóstico por imagem
16.
Radiat Prot Dosimetry ; 198(9-11): 554-559, 2022 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-36005965

RESUMO

Interventional radiology represents subspecialty of radiology, which does not use imaging modalities only for diagnostics, but mostly for therapeutic purposes. Realisation of interventional procedures is done through X-rays, which replaces direct visual control done by interventional radiologist or cardiologist. For the targeted reduction of the radiation exposure, the interventional radiology staff use personal protective equipment. Usually, aprons with lead-equivalent are used, which provide protection for 75% of the radiosensitive organs. As the eye lens and thyroid gland belong to the radiosensitive organs, lead eyeglasses and thyroid collar are commonly used for their protection. Cap and gloves with lead-equivalent can be utilised as an additional personal protective equipment, that is commercially available. Innovative protection systems, such as mobile radiation protection cabin and suspended radiation protection, have been designed to ensure better radiation protection and safety. These systems provide the comfort for the interventional radiologists at work, while offering better protection against ionising radiation.


Assuntos
Cristalino , Exposição Ocupacional , Exposição à Radiação , Proteção Radiológica , Humanos , Exposição Ocupacional/análise , Exposição Ocupacional/prevenção & controle , Roupa de Proteção , Doses de Radiação , Exposição à Radiação/prevenção & controle , Proteção Radiológica/métodos , Radiologia Intervencionista/métodos
17.
Radiat Prot Dosimetry ; 198(9-11): 580-585, 2022 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-36005993

RESUMO

The aim of this contribution is to provide an overview of comparison of two types of eye lens dosemeter systems. The comparison was performed at the Department of Intravenous Cardiology using patient and physician phantoms and supplemented by dose simulation using the Monte Carlo method. The tests were performed in several specific geometries and in addition to eye lens dosemeters the value of a personal dosemeter located at the reference point was also monitored. The value of Hp(3) and Hp(10) was monitored. It is clear from the results that film dosemeters achieve more correct results in most cases. It is probably due to a better correction for the angle of exposure. This assumption must be verified by more detailed measurements in laboratory conditions.


Assuntos
Cardiologia , Cristalino , Exposição Ocupacional , Proteção Radiológica , Cardiologia/métodos , Humanos , Exposição Ocupacional/análise , Doses de Radiação , Proteção Radiológica/métodos , Radiologia Intervencionista/métodos
18.
Contrast Media Mol Imaging ; 2022: 5383146, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35909588

RESUMO

The abnormal proliferation, migration, and epithelial-mesenchymal transformation (EMT) of lens epithelial cells (LECs) are the main reasons for vision loss caused by posterior capsular opacification (PCO) after cataract surgery. Insulin-like growth factor-1 (IGF-1) was found to be associated with the pathogenesis of cataracts, but its biological role in PCO is poorly understood. In the present study, IGF-1 overexpression facilitated the proliferation, migration, and EMT, whereas knockdown of IGF-1 markedly suppressed the proliferation, migration, and TGF-ß2-induced EMT of LECs. Additionally, to evaluate valuable microRNAs (miRNAs) which target IGF-1 to modulate LEC-EMT, we predicted miR-3666 might regulate IGF-1 by binding its 3'UTR according to the bioinformatics database. Furthermore, we verified that miR-3666 directly targeted IGF-1 by luciferase reporter assay. By using miR-3666 mimics, cell proliferation, migration, and invasion were suppressed, while being enhanced by the reduction of miR-3666. Knockout of IGF1 reverses the effect of the miR-3666 inhibitor on the malignant behavior of LECs. These results indicate the role of miR-3666/IGF-1 in LEC-EMT that offers new strategies for the therapy and prevention of PCO.


Assuntos
Opacificação da Cápsula , Fator de Crescimento Insulin-Like I , Cristalino , MicroRNAs , Opacificação da Cápsula/genética , Opacificação da Cápsula/metabolismo , Opacificação da Cápsula/patologia , Movimento Celular/genética , Proliferação de Células , Células Epiteliais/metabolismo , Células Epiteliais/patologia , Transição Epitelial-Mesenquimal/genética , Transição Epitelial-Mesenquimal/fisiologia , Humanos , Fator de Crescimento Insulin-Like I/genética , Fator de Crescimento Insulin-Like I/metabolismo , Cristalino/metabolismo , Cristalino/patologia , MicroRNAs/genética , MicroRNAs/metabolismo
19.
Artigo em Chinês | MEDLINE | ID: mdl-35785894

RESUMO

Objective: To compare the ophthalmic examination indices of different occupational groups in Shenzhen and analyze the possible health problems, so as to provide research basis for further health intervention. Methods: In March 2021, 5426 professionals with ophthalmic examination index data were selected from the basic health database of "Shenzhen occupational population protection action". Among them, radiation workers (694), port operators (1756), sanitation workers (946), teachers (224), video workers (154), police (927) and firefighters (100) were selected as the investigated occupational population. They were exposed to noise 625 workers with traditional occupational hazards such as noise, chemical poisons and dust were used as the control population.Ophthalmic examination indices included right eye vision, left eye vision, outer eye, conjunctiva, cornea, lens, and fundus oculi. The differences of each index in different occupational groups were compared. Results: Compared with the control group, the port operator group showed lower abnormal rates of binocular vision and fundus oculi (P<0.05), but higher abnormal rates of conjunctiva (P=0.029), the environmental sanitation worker group showed higher abnormal rates of binocular vision and conjunctiva (all P<0.01), the teacher group had higher abnormal rates of binocular vision, but only the difference of left eye vision was statistically significant (P=0.021), and the video worker group had higher abnormal rates of right and left eyes vision (P=0.029、0.006) . Conclusion: There were some degrees of ophthalmic problems in different occupational population, therefore targeted intervention measures should be taken according to the characteristics of each group.


Assuntos
Cristalino , Doenças Profissionais , Poeira , Humanos , Ruído , Doenças Profissionais/epidemiologia , Ocupações
20.
Phys Med ; 100: 129-134, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35809498

RESUMO

PURPOSE: Fluoroscopy guided interventional procedures guarantee high benefits for patients, but are associated with high levels of radiation exposure for the medical staff. Their increasing use and complexity results in even higher radiation exposures, with a risk to exceed the annual dose limit of 20 mSv for the eye lens. The aim of the study was to evaluate the potential dose reduction of eye lens exposure for lead glasses and for two types of visors (half and full), used by physicians performing interventional procedures. METHODS: Eye lens dose measurements were carried out on an anthropomorphic phantom simulating a physician performing a fluoroscopy guided interventional procedure. Dose reduction factors were calculated using high sensitivity thermoluminescent dosimeters. Moreover, a spatial dose distribution was generated for the two visors. RESULTS: The dose reduction coefficient was found to be 1.6 for the glasses, 1.2 for the half visor and 4.5 for the full visor. CONCLUSIONS: Optimal radiation protection requires a combination of different radiation protection equipment. Full visors that cover all the face of the operator are recommended, as they absorb scattered radiation reaching the eyes from all directions. Full visors should be prioritized over radiation protection glasses for cases where other protective equipment such as ceiling shielding cannot be used.


Assuntos
Cristalino , Exposição Ocupacional , Exposição à Radiação , Proteção Radiológica , Redução da Medicação , Fluoroscopia , Humanos , Exposição Ocupacional/prevenção & controle , Doses de Radiação , Exposição à Radiação/prevenção & controle , Proteção Radiológica/métodos , Radiologia Intervencionista
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