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1.
J Vet Intern Med ; 38(1): 363-369, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38051604

RESUMO

BACKGROUND: Listeriosis is a severe foodborne infection caused by Listeria monocytogenes, an important foodborne pathogen of animals and humans. Listeriosis is a rare disease in cats. OBJECTIVE: To describe the clinical, diagnostic imaging, histological, and microbiological features of L. monocytogenes-associated mesenteric lymphadenitis in a cat. ANIMALS: Listeria monocytogenes-associated mesenteric lymphadenitis was confirmed in a cat by histology and microbiology. RESULTS: Two distinct isolates of L. monocytogenes were cultured from the affected mesenteric lymph node and whole genome sequencing was performed. CONCLUSION AND CLINICAL IMPORTANCE: This report should alert veterinary clinicians and microbiologists to the syndrome, which may have implications for health and food safety in animals and humans.


Assuntos
Doenças do Gato , Listeria monocytogenes , Listeriose , Linfadenite Mesentérica , Humanos , Gatos , Animais , Listeria monocytogenes/genética , Linfadenite Mesentérica/genética , Linfadenite Mesentérica/veterinária , Microbiologia de Alimentos , Listeriose/veterinária , Listeriose/microbiologia , Genômica
2.
Arch Iran Med ; 26(12): 679-687, 2023 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-38431948

RESUMO

BACKGROUND: Despite the COVID-19 pandemic, there is little information about the different clinical aspects of COVID-19 in children. In this study, we assessed the clinical manifestations, outcome, ultrasound, and laboratory findings of pediatric COVID-19. METHODS: This retrospective study was conducted on 185 children with definitive diagnosis of COVID-19 between 2021 and 2022. The patients' information was retrieved from hospital records. RESULTS: The average age of the patients was 5.18 ± 4.55 years, and 61.1% were male. The most frequent clinical manifestation was fever (81.1%) followed by cough (31.9%), vomiting (20.0%), and diarrhea (20.0%). Mesenteric lymphadenitis was common on ultrasound and found in 60% of cases. In-hospital death was identified in 3.8% of cases. The mean length of hospital stay was 8.5 days. Mandating intensive care unit (ICU) stay was found in 19.5% and 5.9% of cases were intubated. Acute respiratory distress syndrome (ARDS), lower arterial oxygen saturation, higher white blood cell (WBC) count, and higher C-reactive protein (CRP) were the main determinants of death. Lower age, respiratory distress, early onset of clinical manifestations, lower arterial oxygen saturation, lower serum hemoglobin (Hb) level, and higher CRP level could predict requiring ICU admission. CONCLUSION: We recommend close monitoring on CRP, serum Hb level, WBC count, and arterial level of oxygenation as clinical indicators for potential progression to critical illness and severe disease. Mesenteric lymphadenitis is a common sonographic finding in pediatric COVID-19 which can cause abdominal pain. Ultrasound is helpful to avoid unnecessary surgical interventions in COVID-19.


Assuntos
COVID-19 , Linfadenite Mesentérica , Humanos , Masculino , Criança , Lactente , Pré-Escolar , Feminino , Mortalidade Hospitalar , Pandemias , Estudos Retrospectivos , Ultrassom , Prognóstico , Hospitais , Proteína C-Reativa
3.
Contrast Media Mol Imaging ; 2022: 2681543, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35833064

RESUMO

In order to study the practical application value of abdominal ultrasonography in the diagnosis and treatment of acute abdomen in children, this study uses the method of collecting clinical actual cases and scientific analysis to estimate the clinical diagnostic value of high-frequency ultrasound and low-frequency ultrasound. In order to further clarify its curative effect and treatment advantages, a retrospective analysis of medical records was conducted, and 95 children with acute abdominal pain and suspected appendicitis who were admitted to a hospital from September 2021 to November 2021 were reviewed. ATIL HD15000 color Doppler ultrasound was used for diagnosis. The results are as follows: the sensitivity, specificity, positive predictive value, and negative predictive value of low-frequency probe in the diagnosis of intussusception in children were 83.61%, 73.33%, 92.73%, and 52.38%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value in the diagnosis of mesenteric lymphadenitis were 80.00%, 81.97%, 52.17%, and 94.34%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of high-frequency probe in the diagnosis of intussusception in children were 93.44%, 80.00%, 95.00%, and 75.00%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value in the diagnosis of mesenteric lymphadenitis were 93.33%, 95.08%, 82.35%, and 98.31%, respectively. Among the children with appendicitis confirmed by operation and pathology, 69 cases were detected by high-frequency ultrasound and 4 cases were missed (including 3 cases of acute simple appendicitis and 1 case of perforated appendicitis). The false negative was 4%, there was no false positive, and the sensitivity, specificity and accuracy were 95%, 100%, and 96%. In the same cases, 28 cases were detected by low-frequency ultrasound, 45 cases were missed, the false negative was 61%, and there was no false positive. The sensitivity, specificity, and accuracy were 39%, 100%, and 53%. The sensitivity, accuracy, and false negative of high-frequency ultrasound in the diagnosis of acute appendicitis were significantly higher than that of low-frequency ultrasound. This study shows that ultrasound has high accuracy, sensitivity, and specificity in the diagnosis of acute appendicitis. Low-frequency ultrasound can show the whole picture of the disease and the situation in the abdominal cavity, which can better guide the clinical treatment. Color Doppler hemodynamics is a useful supplement to two-dimensional ultrasound, and ultrasound also plays a positive role in the differential diagnosis of acute appendicitis in children.


Assuntos
Abdome Agudo , Apendicite , Intussuscepção , Linfadenite Mesentérica , Abdome Agudo/diagnóstico por imagem , Doença Aguda , Apendicite/diagnóstico por imagem , Apendicite/patologia , Criança , Humanos , Estudos Retrospectivos , Sensibilidade e Especificidade , Ultrassonografia
4.
Acta Medica (Hradec Kralove) ; 65(1): 25-28, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35793505

RESUMO

BACKGROUND: Acute nonspecific mesenteric lymphadenitis (ANML) is a common cause of acute abdominal pain in children with no specific treatment. METHODS: A total of 13 patients (6 boys, 7 girls) aged 7.3 (5-13.5) years with severe acute abdominal pain were evaluated using ultrasonography and laboratory tests to establish the diagnosis of ANML. They were treated with prednisone 1 mg/kg (max 40 mg daily) for a maximum of 5 days. The intensity of abdominal pain was evaluated before and after treatment using a numeric rating scale. RESULTS: All patients had pain scores above 6/10 before, and below 4/10 after treatment with prednisone. Intensity of abdominal pain after treatment for 1-5 days decreased significantly (p < 0.001), with no recurrence at follow-up within 3 months. All other pre-existing signs and symptoms, such as nausea, vomiting, anorexia, fever, diarrhea, and constipation were found to disappear with no adverse effects of corticosteroid therapy. CONCLUSION: These results suggest that the treatment with prednisone in selective patients with ANML can reduce the duration of abdominal pain.


Assuntos
Abdome Agudo , Linfadenite Mesentérica , Abdome Agudo/etiologia , Dor Abdominal/diagnóstico , Dor Abdominal/tratamento farmacológico , Dor Abdominal/etiologia , Criança , Feminino , Humanos , Masculino , Linfadenite Mesentérica/complicações , Linfadenite Mesentérica/diagnóstico , Projetos Piloto , Prednisona/uso terapêutico
6.
Ugeskr Laeger ; 184(1)2022 01 03.
Artigo em Dinamarquês | MEDLINE | ID: mdl-34983723

RESUMO

Yersinia pseudotuberculosis is a Gram-negative bacterium causing infection in humans through contaminated water and/or food. The infection commonly occurs as gastroenteritis and fever, abdominal pain due to mesenteric lymphadenitis and diarrhoea. Bacteraemia is rare and is typically seen in immunocompromised patients and occurs with different clinical presentations like Far East scarlet-like fever, splenic abscess, or mimic appendicitis. This is a case report of Y. pseudotuberculosis bacteraemia and splenic abscess in a Caucasian male.


Assuntos
Bacteriemia , Linfadenite Mesentérica , Esplenopatias , Infecções por Yersinia pseudotuberculosis , Yersinia pseudotuberculosis , Humanos , Masculino , Infecções por Yersinia pseudotuberculosis/diagnóstico , Infecções por Yersinia pseudotuberculosis/tratamento farmacológico
8.
J Surg Res ; 270: 12-21, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34628159

RESUMO

BACKGROUND: Yersinia infection affects terminal ileum and lymph nodes and could therefore mimic the symptoms of appendicitis. We aimed to systematically characterise the suspected or confirmed abdominal diseases and/or surgeries associated with Yersinia infection. MATERIALS AND METHODS: This systematic review and meta-analysis was reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A protocol (CRD42016053252) was uploaded to PROSPERO. The searches were conducted in PubMed and EMBASE on October 2, 2020. Original reports on patients with abdominal surgical diseases were included. The primary outcome was to characterise suspected or confirmed abdominal surgical diseases and/or surgeries associated with Yersinia infection, while the secondary outcomes were the positive rate of Yersinia species for each disease and surgery, and to investigate the rate of Yersinia spp. in different geographic regions. We calculated the weighted mean prevalence of positive tests for Yersinia spp. for the different diseases and surgeries according to the detection method and for subgroups based on geographic region. RESULTS: From the search, 33 studies were included in the systematic review and 18 in the meta-analysis. Across geographic regions, the weighted mean prevalence for Yersinia spp. was 51% (95% CI 34%-69%) in mesenteric lymphadenitis, 65% (95% CI 45%-85%) in terminal ileitis, and 8% (95% CI 2%-15%) in normal appendices. CONCLUSIONS: Around half of the patients with mesenteric lymphadenitis and terminal ileitis were serologically positive for infections with Yersinia spp. Yersinia infection may cause unnecessary surgery for suspected appendicitis due to symptoms from mesenteric lymphadenitis or terminal ileitis.


Assuntos
Apendicite , Apêndice , Doença de Crohn , Linfadenite Mesentérica , Yersiniose , Apendicite/complicações , Apendicite/diagnóstico , Apendicite/cirurgia , Apêndice/patologia , Doença de Crohn/complicações , Humanos , Linfadenite Mesentérica/diagnóstico , Linfadenite Mesentérica/etiologia , Linfadenite Mesentérica/patologia , Yersiniose/complicações , Yersiniose/diagnóstico , Yersiniose/epidemiologia
9.
Kathmandu Univ Med J (KUMJ) ; 19(73): 47-51, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34812157

RESUMO

Background Mesenteric adenitis in children (≤ 18 years) can present with varied findings often causing a diagnostic confusion. In children, considering the inadequacies in history and physical examination, an accurate clinic-radiological diagnosis backed up with laboratory data as indicated becomes important to avoid misdiagnosis and futile interventions. Objective To study the profile of children evaluated for acute abdominal pain and diagnosed as mesenteric adenitis. Method A retrospective review of children with abdominal symptoms, diagnosed to have mesenteric adenitis between January 2018 and December 2020. Result A total of 85 patients (63 males, 22 females) were identified presenting at mean age of 6 years (range 4 months-16 years). Primary Mesenteric Adenitis (PA) was found in 62, Secondary Mesenteric Adenitis (SA) in 11 and Complicated Primary Mesenteric Adenitis (CPA) was identified in 12. All with PA responded well to supportive care. Those with SA were treated for the primary cause and the ones with Complicated Primary Mesenteric Adenitis were managed by treating the complication. All had a favorable outcome. Conclusion When managing a child with abdominal pain, mesenteric adenitis should be considered. Once clinically suspected, tailored management approach results in fruitful outcome.


Assuntos
Linfadenite Mesentérica , Criança , Feminino , Humanos , Lactente , Masculino , Linfadenite Mesentérica/diagnóstico , Estudos Retrospectivos
10.
Rev. gastroenterol. Perú ; 41(4): 271-274, 20211001. graf
Artigo em Espanhol | LILACS, LIPECS | ID: biblio-1389082

RESUMO

RESUMEN La linfadenitis tuberculosa es la entidad más frecuente de la tuberculosis abdominal, que ocurre por reactivación de un foco latente. Su diagnóstico requiere un alto grado de sospecha, para lo cual requiere estudios endoscópicos, radiológicos e histopatológicos. En la evaluación de las linfadenopatías, la punción y aspiración guiada por ultrasonido endoscópico cumple un rol importante. Presentamos el caso de un paciente varón de 22 años, quien ingresa a Emergencia del Hospital Nacional Arzobispo Loayza por hemorragia digestiva alta secundaría a linfadenitis mesentérica tuberculosa que comprometió la pared gástrica. (AU)


ABSTRACT Tuberculous lymphadenitis is the most common entity of abdominal tuberculosis, which occurs due to reactivation of a latent focus. Its diagnosis requires a high degree of suspicion, for which it requires endoscopic, radiological, and histopathological studies. In the evaluation of lymphadenopathies, endoscopic ultrasound-guided aspiration puncture plays an important role. We present the case of a 22-year-old male patient who was admitted to the Emergency Department of the Arzobispo Loayza National Hospital due to upper gastrointestinal bleeding secondary to tuberculous mesenteric lymphadenitis that compromised the gastric wall. (AU)


Assuntos
Humanos , Masculino , Adulto Jovem , Tuberculose , Endossonografia , Hemorragia Gastrointestinal , Linfadenite Mesentérica
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