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1.
Int J Pharm ; 625: 122097, 2022 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-35952800

RESUMO

Functionalization of natural clay minerals for high value-added pharmaceutical and cosmetic applications receives significant research attention worldwide attributable to a rising demand and ongoing search for green, efficient, economically sustainable and ecofriendly geomaterials. Fibrous clays, i.e. palygorskite and sepiolite, are naturally-occurring hydrated magnesium aluminum silicate clay minerals with 2:1 layer-chain microstructure and one-dimensional nanofibrous morphology. Due to their unique structural, textural and compatibility features, over the past decade, fibrous clays and their organic modified derivatives are increasingly used in the dermopharmaceutical and cosmetic fields as excipients, active agents or nanocarriers to develop novel skin delivery systems or to modify drug release profile for enhanced health effects. This comprehensive review presents the up-to-date information on fibrous clays used in topically-applied products for therapeutic and cosmetic purposes with the focus on their performance-related structural characteristics and the underlying mechanisms. The recent advancement of fibrous clay-based skin delivery systems was summarized in wide range of applications including pelotherapy, wound healing, antimicrobial action, coloration and UV protection. An overview of the commonly used topically-applied dosage forms (powders, hydrogels, films, peloids and Pickering emulsion) as well as the toxicological aspects was also included, which might provide guidance to the design and development of fibrous clay-based skin delivery systems.


Assuntos
Cosméticos , Peloterapia , Silicatos de Alumínio/química , Argila , Minerais/química
2.
Int J Biometeorol ; 66(8): 1699-1710, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35654863

RESUMO

Although it is thought that peloid and paraffin treatments may have positive effect on pain, functional status, and quality of life in patients with hallux rigidus (HR), there are no comprehensive and comparative studies with a high level of evidence. We aimed to compare peloid and paraffin treatments in symptomatic hallux rigidus patients. A total of 113 patients diagnosed with HR between May 2019 and June 2021 were included in the study. After exclusion criteria, the remaining 90 patients were randomly divided into two groups: the peloid therapy group (peloid therapy + home exercise) and the paraffin therapy group (paraffin therapy + home exercise). Peloid and paraffin treatments were applied for 2 weeks (5 days a week for a total of 10 sessions). Patients were evaluated before treatment, at the end of treatment, and one month after treatment. The groups were compared in terms of pain, functional status, quality of life, and joint range of motion. In the final analysis, 40 patients in each treatment group were compared. Statistically significant improvements were achieved for all parameters at the end of treatment and at follow-up, and the treatments were found to be highly effective. As a result of the comparison, the methods were not found to be superior to each other. The present study is the first randomized study comparing peloid therapy and paraffin therapy given as an adjuncts to exercise therapy. Exercise therapy plus peloid and exercise therapy plus paraffin treatments seem to have similar effects on HR; however, controlled trials are necessary for confirmation of our results.


Assuntos
Hallux Rigidus , Peloterapia , Terapia por Exercício , Hallux Rigidus/terapia , Humanos , Dor , Parafina/uso terapêutico , Estudos Prospectivos , Qualidade de Vida , Resultado do Tratamento
3.
J Strength Cond Res ; 36(7): 1909-1915, 2022 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-32956264

RESUMO

ABSTRACT: Bartolomei, S, Nigro, F, D'Amico, A, Cortesi, M, and Di Michele, R. Mud pack with menthol and Arnica montana accelerates recovery following a high-volume resistance training session for lower body in trained men. J Strength Cond Res 36(7): 1909-1915, 2022-The aim of this study was to compare the effects of a mud pack, containing menthol and Arnica montana, on the recovery responses following a high-volume resistance protocol. Ten resistance-trained men (mean ± SD: age = 25.3 ± 6.1 years; body mass = 79.1 ± 10.6 kg; height = 178.9 ± 7.5 cm) performed a high-volume resistance workout for lower body squat and leg extension, (5 sets of 10 reps at 70% of one repetition maximum for both exercises). All the subject used mud (MUD) or a placebo (PL) in randomized counterbalanced crossover design. MUD or PL were applied 4 times: 3, 19, 27, and 45 hours after the workout, on the skin surface above the quadriceps muscle of both legs. Muscle performance (countermovement jump power [CMJP], isokinetic leg press at 75 cm·s-1 and 25 cm·s-1 [ISOK75 and ISOK25, respectively], isometric squat [ISQ]), and morphology (muscle thickness of vastus lateralis [VLMT]), were measured before exercise (baseline [BL]), and 15 minutes (15P), 24 hours (24P), and 48 hours (48P) postexercise. In addition, muscle soreness was assessed at the same time points using a visual analog scale (VAS). No significant interactions (p > 0.05) between the trials were detected for CMJP, ISOK75, ISQ, and VLMT. A significant interaction between trials was noted for ISOK25 (p = 0.022) and for VAS (p = 0.001). ISOK25 was significantly (p < 0.01) reduced from BL at 15P, 24P and 48P in PL, whereas changes were significant (p < 0.05) at 15P and 24P only in MUD. The present findings indicate that MUD may enhance the recovery rate of strength and reduce muscle soreness after high-volume exercise. Muscle morphology do not seem to be influenced by mud packs.


Assuntos
Arnica , Peloterapia , Treinamento de Força , Adulto , Humanos , Masculino , Mentol , Força Muscular/fisiologia , Músculo Esquelético/fisiologia , Mialgia , Treinamento de Força/métodos , Adulto Jovem
4.
Environ Geochem Health ; 44(7): 2101-2110, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33929672

RESUMO

The effects of bath therapy are complex and result from a unique interaction between the aquatic environment and the human body functions. The effect of bath therapy depends on both water temperature and chemical additives (mineral substances and humic substances). Värska Resort Centre, in south-eastern Estonia, uses for the balneotherapy the local curative mud and mineral water. The aim of the study was to evaluate and compare the effects of Värska's local mud bath and mineral water bath on moderate musculoskeletal pains in working-age people. The study involved 64 working-age subjects: within two weeks, 32 of them received five general mineral water baths, and another 32 received five general curative mud baths. Pain was assessed with the Nordic Musculosceletal Questionnaire, and muscle tension was measured with a myotonometer in m. erector spinae and m. trapezius. Measurements were performed three times: before the start of the study, immediately after the last procedure, and 2-3 weeks after the last procedure. Both the Värska curative mud bath and the Värska mineral water bath showed a positive effect on musculoskeletal pain and muscle tension. Both procedures can be recommended as drug-free interventions for mild to moderate musculoskeletal pain syndrome and muscle tensions, in both prevention and treatment.


Assuntos
Balneologia , Águas Minerais , Peloterapia , Dor Musculoesquelética , Banhos , Humanos , Recém-Nascido , Águas Minerais/uso terapêutico , Minerais , Peloterapia/métodos , Tono Muscular , Dor Musculoesquelética/tratamento farmacológico , Síndrome
5.
J Complement Integr Med ; 19(3): 799-806, 2022 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-34757704

RESUMO

OBJECTIVES: Mud pack or compress is an easily accessible, cost-effective, efficient treatment modality used in naturopathy to manage and prevent various chronic illnesses. This study sought to elucidate the effectiveness of cold spinal mud packs on improving neuro-cardiac parameters among hypertensive individuals. METHODS: A total of 100 hypertensive subjects aged 30-50 years were randomly allocated into two groups: Cold spinal mud pack (CSMP) and prone rest. Blood Pressure (BP) and Heart Rate Variability (HRV) were assessed at three-time points: Baseline, After 20 min (T1), After 60 min (T2). This single-blinded randomized controlled trial was registered in the Clinical Trials Registry-India (CTRI/2019/12/022492). RESULTS: After 20 min of CSMP showed a statistically significant reduction (p<0.01) in mean values of Systolic BP, Diastolic BP, and in HRV attained statistically significant change (p<0.01) in mean score in the frequency domain except for Very low-frequency power (VLF) and a significant difference found in the mean score of time-domain values (p<0.01) when compared to control group and 95% confidence interval (CI) will be provided for each effect. CONCLUSIONS: CSMP reduces the sympathetic tone and shifts the sympathovagal balance in favor of parasympathetic dominance, contributing to a decrease in BP and effective changes in components of HRV.


Assuntos
Hipertensão , Peloterapia , Sistema Nervoso Autônomo/fisiologia , Pressão Sanguínea , Frequência Cardíaca/fisiologia , Humanos , Hipertensão/tratamento farmacológico
6.
Int J Biometeorol ; 66(4): 661-668, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34837528

RESUMO

This study aimed to compare the peloid therapy and kinesio tape treatments in chronic lateral epicondylitis. While home exercise program and cold application were applied to the control group, peloid therapy (5 days a week for 3 weeks at 45 °C for 30 min each day, a total of 15 treatment days) was applied in addition to the first group, and kinesio taping (6 treatment days 2 times a week) was applied to the second group. Patients were evaluated with visual analog scale (VAS), grip strength with Jamar hydraulic dynamometer, Arm, Shoulder, and Hand Disabilities (DASH), quality of life in Short Form-36 (SF-36), and Patient-Rated Forearm Evaluation Questionnaire (PRFEQ) was recorded before treatment, after treatment (third week), and 1 month after the end of treatment. In this study, 156 patients with chronic lateral epicondylitis were included. In the follow-up of the patients, there was a statistically significant improvement in the hand grip strength, DASH, PRFEQ, VAS, and SF-36 scores in the 1st month follow-up after the treatment compared to the pre-treatment control in all groups (p < 0.001). At the end of the treatment, the hand grip strength (p = 0.002), DASH (p < 0.001), PRFEQ pain (p < 0.001) and function (p = 0.007), SF-36 physical health (p = 0.002) scores were statistically significant in the peloid therapy group compared to the control group. At the 1st month after the end of treatment, hand grip strength, VAS, DASH, PRFEQ pain, function, daily activities, and SF-36 physical health scores (all of p < 0.001) were statistically significant in the peloid treatment group compared to the control group. Peloid treatment was found to be more effective than kinesio taping in SF-36 physical health (p = 0.007) and PRFEQ pain (p = 0.003) scores in the 1st month follow-up after treatment. Peloid therapy in addition to exercise seems more effective in chronic lateral epicondylitis. Randomized controlled long-term studies are needed.ClinicalTrials ID: NCT04687943.


Assuntos
Fita Atlética , Peloterapia , Cotovelo de Tenista , Força da Mão , Humanos , Qualidade de Vida , Método Simples-Cego , Cotovelo de Tenista/terapia , Resultado do Tratamento
7.
Mar Drugs ; 19(12)2021 Nov 26.
Artigo em Inglês | MEDLINE | ID: mdl-34940665

RESUMO

Peloids have been used for therapeutic purposes since time immemorial, mainly in the treatment of locomotor system pathologies and dermatology. Their effects are attributed to their components, i.e., to the properties and action of mineral waters, clays, and their biological fraction, which may be made up of microalgae, cyanobacteria, and other organisms present in water and clays. There are many studies on the therapeutic use of peloids made with microalgae/cyanobacteria, but very little research has been done on dermocosmetic applications. Such research demonstrates their potential as soothing, regenerating, antioxidant, anti-inflammatory, and antimicrobial agents. In this work, a method for the manufacture of a dermocosmetic peloid is presented based on the experience of the authors and existing publications, with indications for its characterization and study of its efficacy.


Assuntos
Argila , Microalgas , Águas Minerais , Animais , Organismos Aquáticos , Cosméticos , Peloterapia
8.
Reumatismo ; 73(3)2021 Nov 22.
Artigo em Inglês | MEDLINE | ID: mdl-34814657

RESUMO

The primary objective of this study was to assess the efficacy of mud plus bath therapy in comparison to bath therapy alone in hand and knee osteoarthritis (HOA and KOA). We conducted a single-blinded randomized controlled trial (RCT). Patients were randomly assigned to either mud plus bath therapy (group 1) or balneotherapy (group 2). The primary outcome was a change in AUSCAN questionnaire for HOA and in WOMAC for KOA at month 12. Evaluations were performed at baseline (B), immediately after the interventions (week 2, W2) and after 3 (M3), 6 (M6), 9 (M9) and 12 (M12) months. 37 patients with KOA and 52 with HOA were randomized in the study. In HOA patients, AUSCAN pain improved more in group 1 compared to group 2 at M3, M6 and M12 (p<0.001, p=0.001 and p=0.038, respectively). AUSCAN stiffness improved more in group 1 at M3 (p=0.001). AUSCAN function improved more at M3, M6, M9 and M12 (p=0.001, p=0.001, p=0.014 and p=0.018, respectively). Regarding, KOA, WOMAC function decreased more prominently in group 1 compared to group 2 at M9 (p=0.007). The absolute values of WOMAC function at M6 and M9 were lower in group 1 compared to group 2 (p=0.029 and p=0.001, respectively). WOMAC pain absolute values were lower in group 1 at W2 (p=0.044) and at M9 (p=0.08). We conducted a RCT on the efficacy of mud plus balneotherapy over balneotherapy alone in HOA and KOA. We found that mud plus balneotherapy was more effective than balneotherapy alone on clinical outcomes of HOA. Differences in clinical outcomes of KOA were not significant, yet numerically higher.


Assuntos
Balneologia , Peloterapia , Osteoartrite do Joelho , Mãos , Humanos , Osteoartrite do Joelho/terapia , Resultado do Tratamento
9.
Artigo em Russo | MEDLINE | ID: mdl-34719912

RESUMO

Over the past decades, a small yet convincing evidence base has accumulated that demonstrates the effectiveness of dental care for patients in health-resort (HR) settings. In addition to a positive local effect, complex HR care increases nonspecific resistance and promotes desensitization. OBJECTIVE OF THE REVIEW: Addressing the HR rehabilitation in patients with various maxillofacial diseases for further consideration of the possibility of the increased use of HR care in dental practice. MATERIAL AND METHODS: Russian and English-language publications were analyzed without specifying the search timeframe. The search keywords were the following: «health-resort care¼, «balneotherapy¼, «peloid therapy¼, «physiotherapy¼, «magnet therapy¼, «laser therapy¼ in combination with «dental diseases¼, «maxillofacial diseases¼, «periodontal diseases¼, «temporomandibular joint diseases¼, «postoperative rehabilitation¼ «balneotherapy¼, «mud therapy¼, «peloid therapy¼, «spa therapy¼, «physiotherapy¼. A total of 21 articles were analyzed, including 10 related to periodontal disease, 5 to temporomandibular joint pathology, and 6 to rehabilitation in the postoperative period. Seventeen original studies (3855 patients) were selected, including 47.62% with evidence level C, due to lack of information on comparison group or randomization. RESULTS AND DISCUSSION: Available data from clinical studies suggest the effectiveness of natural and physiotherapeutic factors in the medical rehabilitation of patients with various dental diseases. Further randomized clinical trials and the development of clinical guidelines for various techniques in dental diseases are warranted.


Assuntos
Balneologia , Terapia com Luz de Baixa Intensidade , Peloterapia , Assistência Odontológica , Estâncias para Tratamento de Saúde , Humanos
10.
Clin Ter ; 172(4): 372-387, 2021 Jul 05.
Artigo em Inglês | MEDLINE | ID: mdl-34247222

RESUMO

OBJECTIVE: Osteoarthritis (OA) results from loss of cartilage in-tegrity in association with changes to the structure of the entire joint. Treatment of OA is based on different pharmaceutical and no phar-maceutical approaches and the latter include the use of spa-therapy. The biological effects of mud-bath therapy are mainly secondary to heat stimulation and to physic-chemical properties of mineral waters and mud-packs. Mud-bath therapy likely exerts its effects modulating several cytokines and other molecules involved in inflammation and cartilage degradation. Our aim was to perform an updated meta-analysis of the effectiveness of the mud-bath therapy on knee osteoarthritis and briefly to discuss the mechanisms of action of this treatment. MATERIALS AND METHODS: A MEDLINE on PubMed for articles on knee OA and spa therapy published from 1995 through up to April 2019 was performed. Then, we checked the Cochrane Central Register of Controlled Trials to find additional references included up to April 2019. Articles were included if in accordance with the eligibility cri-teria. Sample size and effect sizes were processed with the MedCalc software package. RESULTS: Twenty one studies met the inclusion criteria and were included in meta-analysis. We examined WOMAC Index and VAS pain. We found significant improvements in function scores and painful symptoms after mud-bath therapy in patients with knee joint osteoarthritis. CONCLUSIONS: Spa therapy is a non-drug treatment modalities, non invasive, complication-free, and cost-effective alternative modality for the conservative treatment of knee osteoarthritis. It cannot substitute for conventional therapy but can integrated or alternated to it. Treatment with mud-bath therapy may relieve pain, stiffness and improve functio-nal status in patients with knee OA.


Assuntos
Articulação do Joelho/fisiopatologia , Águas Minerais/uso terapêutico , Peloterapia/métodos , Osteoartrite do Joelho/terapia , Manejo da Dor/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
11.
Environ Geochem Health ; 43(12): 4919-4937, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34181138

RESUMO

Many of therapeutic treatments in spas are concentrated on mud therapy. Clays are included in the formulation of thermal mud as vehicles of the mineral medicinal water. To be suitable for therapeutic use, some mineralogical, rheological and thermal properties should be respected in order to be topically applied. Our objective is to explore the suitability of three Tunisian commercial green clays traditionally used as facial and body masks by women in the region of Douiret (CD), Tozeur (CT) and Korbous (CK) in terms of their physicochemical structure chemical composition, heavy metals risk assessment, thermal properties, plasticity, rheology and their potential application as peloid with distilled and sodium chloride-rich sulfated thermal waters from hot spring in the region of hammam Lif and Korbous and sea waters. The mineralogy of samples (clay fraction and associated minerals) was determined by X-ray powder diffraction and FT-IR analysis, and the chemical composition was obtained by ICP. The main clay fraction of the samples was smectite and illite with significant amount of kaolinite. Regarding their mineralogical properties, the samples with a high amount of smectite fraction are more suitable for use in Tunisian spas and for the application as peloids. The thermal analyses of clay powders shows a specific heat value comparable to those use used in spas. Also the muds showed a low cooling rate which is necessary for therapeutic use. Rheological properties of peloids prove their thixotropic characteristics.


Assuntos
Peloterapia , Argila , Humanos , Reologia , Água do Mar , Espectroscopia de Infravermelho com Transformada de Fourier
12.
Int J Biometeorol ; 65(11): 1799-1809, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-33931829

RESUMO

The aim of this study was to compare peloid therapy in addition to home exercise with home exercise alone in terms of pain, function, quality of life, and depression in patients with chronic low back pain (cLBP). A total of 106 cLBP patients were divided into two equal groups as treatment and control. The peloid therapy group had peloid therapy (with a total of 15 sessions on 5 days per week for 3 weeks duration with 45 °C temperature lasting 30 min/day) + home exercise program. The control group was only given a home exercise program. Patients completed the visual analog scale-pain (VAS-pain), patient and physician global assessments (VAS-PGA and VAS-PhGA), revised Oswestry disability index (rODI) for functional status, the short form-36 (SF-36) for quality of life, and Beck Depression Inventory (BDI) for depression three times as before treatment, after treatment (3rd week), and 1 month after the end of treatment. Assessments in the 3rd week at the end of treatment revealed statistically significant improvements for rODI (p = 0.013), VAS-pain (p = 0.039), and VAS-PhGA (p = 0.002) parameters in the peloid therapy group compared to the control group. Assessments in the 1st month after the end of treatment revealed statistically significant improvements in rODI (p < 0.001), VAS-pain (p < 0.001), VAS-PGA (p = 0.002), VAS-PhGA (p < 0.001), and SF-36VE (p = 0.022) parameters in the peloid therapy group compared to the control group. Peloid therapy + home exercise was statistically significantly superior to home exercise alone in improving pain and function in patients with cLBP. Peloid therapy may be recommended as a non-pharmacological treatment for cLBP patients. There is a need for randomized studies with longer follow-up including biochemical parameters to verify the beneficial effects observed in this study and elaborate the mechanisms of action.


Assuntos
Dor Crônica , Dor Lombar , Peloterapia , Dor Crônica/terapia , Terapia por Exercício , Humanos , Dor Lombar/terapia , Qualidade de Vida , Método Simples-Cego , Resultado do Tratamento
13.
Int J Biometeorol ; 65(7): 1255-1271, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33740137

RESUMO

Osteoarthritis is a degenerative disease considered a leading cause of functional disability. Its treatment is based on a combination of pharmacological and non-pharmacological interventions, but the role of these latter is still debated. This overview of systematic reviews aimed at evaluating the short-term efficacy of different thermal modalities in patients with osteoarthritis. We searched PubMed, Scopus, CINHAL, Web of Science, ProQuest and the Cochrane Database of Systematic Reviews from inception until October 2020, with no language restrictions. We selected the following outcomes a priori: pain, stiffness and quality of life. Seventeen systematic reviews containing 27 unique relevant studies were included. The quality of the reviews ranged from low to critically low. Substantial variations in terms of interventions studied, comparison groups, population, outcomes and follow-up between the included SRs were found. From a re-analysis of primary data, emerged that balneotherapy was effective in reducing pain and improving stiffness and quality of life, mud therapy significantly reduced pain and stiffness, and spa therapy showed pain relief. However, the evidence supporting the efficacy of different thermal modalities could be seriously flawed due to methodological quality and sample size, to the presence of important treatment variations, and to the high level of heterogeneity and the absence of a double-blind design. There is some encouraging evidence that deserves clinicians' consideration, suggesting that thermal modalities are effective on a short-term basis for treating patients with AO.


Assuntos
Balneologia , Peloterapia , Osteoartrite , Humanos , Osteoartrite/terapia , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto , Revisões Sistemáticas como Assunto
14.
Artigo em Inglês | MEDLINE | ID: mdl-33670514

RESUMO

The use of peloids as heat-providing therapeutic systems dates back to antiquity. Such systems consist of a liquid phase and an organic or inorganic solid phase. The latter facilitates the handling, preparation and stability of the solid-liquid system, modifying its organoleptic and phy-sicochemical properties, and improves its efficacy and tolerance. Peloids enable the application of heat to very specific zones and the release of heat at a given rate. The aims of this work are to study 16 reference peloids used in medical spa centers as thermo-therapeutic agents as well as to propose nine raw materials as a solid phase for the preparation of peloids. The physical properties studied are the centesimal composition, the instrumental texture and the thermal parameters. In conclusion, the peloids of the medical spas studied are used as thermotherapeutic agents in the treatment of musculoskeletal disorders, especially in knee osteoarthritis and to a lesser extent in back pain and psoriatic arthropathy. The clinical experience in these centers shows that the main effects of the application of their peloids are the reduction of pain, an increase in the joint's functional capacity and an improvement in the quality of life. As thermotherapeutic agents, all the peloids of the me-dical spas studied and the pastes (raw materials with distilled water) examined showed a heat flow rate of up to four times lower than that shown by the same amount of water. The raw materials studied can be used as solid phases for the preparation of peloids with mineral waters.


Assuntos
Águas Minerais , Peloterapia , Temperatura Alta , Qualidade de Vida
15.
Sci Rep ; 10(1): 21527, 2020 12 09.
Artigo em Inglês | MEDLINE | ID: mdl-33299027

RESUMO

Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to start detailed and systematic research on the medical properties of sapropel to be obtained in Latvia, promote its scientifically based use in balneology, develop new medical procedures and services, and promote development of new exportable products. The results include the survey, sampling depths, and processing, evaluation of external signs, physical, chemical, and biochemical parameters, and evaluation of microbiological indicators. Active components from the sapropel samples extracted using the alkaline method. Sapropel extracts were characterized by organic carbon content, humic and fulvic acid concentrations, total phenolic content, trace metal and pesticide concentrations, total antioxidant status, and microbiological flora. Summarizing the article's main findings it was concluded that Latvian freshwater sapropel can be used as raw material for obtaining sapropel extract and use it in the preparation of pharmaceuticals and promote the development of new exportable products and services.


Assuntos
Benzopiranos/farmacologia , Solo/química , Poluição Ambiental , Substâncias Húmicas/análise , Lagos , Letônia , Peloterapia/métodos , Preparações Farmacêuticas , Oligoelementos
16.
Environ Geochem Health ; 42(11): 3507-3527, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32607701

RESUMO

This article aims to draw an overview on the actual knowledge on bacteriostatic and bactericidal natural clays. Particular emphasis is given to the role of clay itself, the action of reduced metals located either in the structure of clay minerals or external to them as constituents of associate minerals, and the definition of the mechanisms of action based on the achievements found in all available studies being carried out so far. The term bactericidal is herein used when a clay or a clay mineral kill the bacteria, whereas the term bacteriostatic is used when those minerals stop bacteria growth and replication. The second part of this article deals with experimental studies on bactericidal natural clay, experience and perspective for the preparation of bactericidal natural clays, interesting on the authors perspective and experience for the preparation of pathogens safe both therapeutic and cosmetic natural mud/natural peloid, and better yet of both therapeutic 87oooand cosmetic peloid itself and designed and engineered peloid. The authors also show how to convert non-antimicrobial clay into antimicrobial one, opening the way in the field of pelotherapy to the preparation of sanitary safe peloids addressed, for instance, to the treatment of rheumatic disabilities, as well as to the preparation of antimicrobial peloids and, in particular, of dermatological ointments, all able to fight infectious skin disorders.


Assuntos
Antibacterianos/química , Antibacterianos/farmacologia , Argila , Argila/química , Sistemas de Liberação de Medicamentos , Humanos , Metais/química , Minerais/química , Peloterapia
17.
Artigo em Inglês | MEDLINE | ID: mdl-32668799

RESUMO

Evaluation of hygienic aspects of thermal mud microbiology is still neglected. This study evaluates the microbiological hygiene quality of thermal muds, providing a comprehensive assessment of the whole mud cultivation chain. Maturing mud, peloid and used mud samples were collected twice in a year from 30 SPAs of the Euganean Thermal District, NE Italy. Samples were processed with an ad hoc laboratory method. The following indicator parameters were assessed: Total Count at 22, 37 and 55 °C; total coliforms; Escherichia coli; enterococci; Staphylococcus aureus; Pseudomonas aeruginosa; sulfite-reducing clostridia; dermatophytes. Statistical significance of differences between the two sampling campaigns and correlation between temperature and indicator parameters were evaluated. One-hundred eighty samples were analyzed. Widespread presence of environmental species was found, as well as hints of possible microorganism transfer from the patient's skin to the mud. Proper setting of thermal water temperature resulted critical, in terms of hygienic quality. Although optimal maturation should be granted (thermal water at 30-42 °C), a pasteurization step at 60-65 °C is strongly recommended to sanitize peloids before pelotherapy. Facilities re-using thermal muds should also implement a regeneration step at ≥65 °C. Core evaluation of thermal mud hygienic quality could encompass the following guidelines: absence (i.e., 0 colony forming units (CFU)/g) of E. coli, P. aeruginosa, S. aureus and dermatophytes.


Assuntos
Bactérias , Higiene , Peloterapia , Bactérias/isolamento & purificação , Escherichia coli , Humanos , Itália , Projetos Piloto , Staphylococcus aureus
18.
Georgian Med News ; (302): 113-122, 2020 May.
Artigo em Russo | MEDLINE | ID: mdl-32672702

RESUMO

This study purpose was to research the possibility of microscopic analysis using for therapeutic mud (peloids) identification. The samples were studied: products containing native mud for use as cosmetics; sulfide-silt mud of the BolshoyTambukanlake (Stavropol region) and the Saki lake (Crimea). The microscopic analysis of raw materials was carried out in accordance with OFS 1.5.3.0003.15. For identification of the algae the database of the website https://www.algaebase.org/content/ was used. The difference between microscopic features of different genesis muds deposits: sulfide-silt, sapropel and peat was determined. Sulfide-silt muds were characterized by the presence of a large number of mineral particles, including various shapes salt crystals, blue-black hydrotroilite particles, dark brown humus particles, and rare algae inclusions. Sapropel mud was characterized by the presence of a significant number of semi-decomposed plant residues fragments and fragments of plant tissues, algae, pollen of higher coastal plants, and a small number of mineral particles. Peat mud contained numerous fragments of half-decomposed plant residues (conductive and mechanical tissues), fragments of mosses, the absence of algae and mineral particles is noted. Thus, the microscopic method of analysis can be used to assess the authenticity and quality of therapeutic mud of various origins along with the macroscopic method. Further research is promising to clarify the microscopic characteristics of raw materials for the development of regulatory documentation for therapeutic mud intended for use in cosmetics.


Assuntos
Peloterapia , Microscopia , Minerais , Solo , Sulfetos
19.
Artigo em Russo | MEDLINE | ID: mdl-32592576

RESUMO

The article is devoted to the history of the creation and establishment of the Far Eastern resort «Talaya¼, located in the Far North of Russia, in the Magadan Region among the hills of the Kolyma Range, in the valley of the Talaya River. A historical essay is presented from 1868 to the present days, including periods of the resort's development at various stages of Russia's formation (pre-revolutionary, post-revolutionary periods, the era of developed socialism, present times). The contribution of resort doctors, geologists, employees of research institutes to the study of the mechanism of action and clinical effectiveness of the use of Tal mineral water is described. The balneological characteristic of nitrogen-siliceous thermal water, the main therapeutic factor of the Talaya resort, is given. Currently, the Talaya sanatorium is providing the treatment of patients with diseases of the skin, musculoskeletal system, gynecological, neurological diseases, diseases of the digestive system, metabolism, upper respiratory tract, cardiovascular system, occupational diseases using balneotherapy, mud therapy and others methods of non-drug therapy. Hundreds of thousands of northerners were healed by the Kolyma health resort, which gained fame as the «Northern Pearl¼. Today, during the reorganization of health care, the Talaya sanatorium is going through a difficult but interesting period in improving the possibilities of healing the inhabitants of the northern regions of Russia.


Assuntos
Balneologia , Águas Minerais , Peloterapia , Estâncias para Tratamento de Saúde , Humanos , Federação Russa
20.
Medicine (Baltimore) ; 99(17): e19761, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32332614

RESUMO

The objective of this review is to systematically evaluate the short-term efficacy of mud therapy in the treatment of knee osteoarthritis (KOA).Randomized controlled trials, in which treatment of KOA is mud therapy, were included by systematically searching the PubMed, Embase, and the Cochrane Library databases.According to inclusion criteria and searching method, 11 articles, containing a total of 1106 patients, were included in the study. Our results showed significant differences in visual analog scale pain score and Western Ontario and McMaster Universities Osteoarthritis Index (pain, stiffness, function). In addition, the heterogeneity of study included is lower (I < 25%).According to the results of this meta-analysis, mud therapy can effectively alleviate the pain and improve joint function for KOA.


Assuntos
Peloterapia/normas , Osteoartrite do Joelho/terapia , Fatores de Tempo , Humanos , Peloterapia/métodos , Osteoartrite do Joelho/psicologia , Resultado do Tratamento
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