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1.
Food Chem ; 400: 134087, 2023 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-36084599

RESUMO

Apergillus carbonarius and Aspergillus niger are the principal fungi that attack table grapes, and they are responsible for producing and contaminating these fruits with ochratoxin A. Packaging containing essential oils from Ocimum gratissimum L. and Ocimum basilicum L. encapsulated in poly(lactic acid) (PLA) nanofibers were produced, the antifungal and antiocratoxigenic activities against A. carbonarius and A. niger were evaluated in vitro and in vivo, and the effect of these packages on the quality of table grapes was determined. The nanofibers were produced by the Solution Blow Spinning technique and characterized by Scanning Electron Microscopy and Thermogravimetric Analysis. Fungal contamination and ochratoxin A production were significantly controlled by PLA nanofibers containing the essential oils and the physicochemical parameters of the grapes were preserved, preserving the quality and the shelf life of the fruit. Therefore, the active packaging developed herein has potential and may be suitable for application in fruits.


Assuntos
Nanofibras , Ocratoxinas , Ocimum basilicum , Ocimum , Óleos Voláteis , Vitis , Antifúngicos , Aspergillus , Aspergillus niger , Ocimum/química , Óleos Voláteis/química , Óleos Voláteis/farmacologia , Poliésteres , Vitis/química
2.
Food Chem ; 399: 133962, 2023 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-36007440

RESUMO

Recently, intelligent packaging has emerged for monitoring food quality in food industry. This study aimed to develop the electrospun HACC/PCL/SKN nanofibrous films with improved antimicrobial and antioxidant activity as intelligent packaging to monitor food freshness. The SKN loading resulted in nanoscale uniform fibers (approximately 55.0 nm), and the HACC/PCL/SKN nanofibrous films presented improved hydrophobicity, barrier properties and mechanical properties. Release kinetics study demonstrated that the loading effect led to a sustained release of SKN from fibers. The HACC/PCL film containing 2 wt% SKN showed good antibacterial effect during 24 h, suggesting enhanced antimicrobial activity. Moreover, the SKN-based solutions and films exhibited pH-responsive color changes from red (pH 2) to blue-purple (pH 12). Finally, the HACC/PCL/SKN film effectively provided a spoilage indication for shrimp stored at different temperatures for 3 days by color changes. This work provides a promising strategy for developing multi-functional film as an intelligent packaging in food industry.


Assuntos
Anti-Infecciosos , Quitosana , Nanofibras , Antocianinas/química , Anti-Infecciosos/farmacologia , Quitosana/química , Embalagem de Alimentos/métodos , Concentração de Íons de Hidrogênio , Naftoquinonas , Poliésteres
3.
Int J Nanomedicine ; 17: 3913-3931, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36097445

RESUMO

As a type of biological macromolecule, natural polysaccharides have been widely used in wound healing due to their low toxicity, good biocompatibility, degradability and reproducibility. Electrospinning is a versatile and simple technique for producing continuous nanoscale fibers from a variety of natural and synthetic polymers. The application of electrospun nanofibers as wound dressings has made great progress and they are considered one of the most effective wound dressings. This paper reviews the preparation of polysaccharide nanofibers by electrospinning and their application prospects in the field of wound healing. A variety of polysaccharide nanofibers, including chitosan, starch, alginate, and hyaluronic acid are introduced. The preparation strategy of polysaccharide electrospun nanofibers and their functions in promoting wound healing are summarized. In addition, the future prospects and challenges for the preparation of polysaccharide nanofibers by electrospinning are also discussed.


Assuntos
Nanofibras , Bandagens , Polissacarídeos , Reprodutibilidade dos Testes , Cicatrização
4.
Sci Rep ; 12(1): 15460, 2022 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-36104428

RESUMO

Electrospinning nanofibers have a tremendous interest in biomedical applications such as tissue engineering, drug administration, and wound healing because of their ability to replicate and restore the function of the natural extracellular matrix found in tissues. The study's highlight is the electrospinning preparation and characterization of polyacrylonitrile with chicken feather keratin as an additive. In this study, keratin was extracted from chicken feather waste using an environmentally friendly method and used to reinforce polymeric nanofiber mats. Scanning electron microscopy, energy dispersive spectroscopy, and transmission electron microscopy were used to examine the morphology and the structure of the prepared nanofiber mats. The effect of keratin on the porosity and the tensile strength of reinforcing nanofibers is investigated. The porosity ratio of the nanofiber mats goes up from 24.52 ± 2.12 for blank polyacrylonitrile (PAN (NF)) to 90.89 ± 1.91% for polyacrylonitrile nanofiber with 0.05 wt% keratin (PAN/0.05% K). Furthermore, keratin reinforcement improves the nanofiber's mechanical properties, which are important for wound dressing application, as well as its antibacterial activity without causing hemolysis (less than 2%). The best antibacterial activities were observed against Pseudomonas aeruginosa (30 ± 0.17 mm inhibition zone) and Staphylococcus aureus (29 ± 0.31 mm inhibition zone) for PAN/0.05% K sample, according to the antibacterial test. This research has a good potential to broaden the use of feather keratin-based nanofibers in wound healing.


Assuntos
Nanofibras , Resinas Acrílicas , Compostos Alílicos , Animais , Antibacterianos/química , Antibacterianos/farmacologia , Bandagens/microbiologia , Galinhas , Plumas , Queratinas , Nanofibras/química , Sulfetos
5.
Sci Rep ; 12(1): 15583, 2022 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-36114221

RESUMO

In this study, piezoelectric composite nanofiber films were fabricated by introducing nitrogen-doped-reduced-graphene-oxide as a conductive material to a P(VDF-TrFE) polymer and a BiScO3-PbTiO3 ceramic composite employing an electrospinning process. Nitrogen was doped/substituted into rGO to remove or compensate defects formed during the reduction process. Electro-spinning process was employed to extract piezoelectric composite nanofiber films under self-poling condition. Interdigital electrodes was employed to make planner type energy harvesters to collect electro-mechanical energy applied to the flexible energy harvester. From the piezoelectric composite with interdigital electrode, the effective dielectric permittivity extracted from the conformal mapping method. By introducing BS-PT ceramics and N-rGO conductors to the P(VDF-TrFE) piezoelectric composite nanofiber films, the effective dielectric permittivity was improved from 8.2 to 15.5. This improved effective dielectric constant probably come from the increased electric flux density due to the increased conductivity. Fabricated interdigital electrode using this thin composite nanofiber film was designed and tested for wearable device applications. An external mechanical force of 350 N was applied to the composite nanofiber-based energy harvester with interdigital electrodes at a rate of 0.6 Hz, the peak voltage and current were 13 V and 1.25 µA, respectively. By optimizing the device fabrication, the open-circuit voltage, stored voltage, and generated output power obtained were 12.4 V, 3.78 V, and 6.3 µW, respectively.


Assuntos
Grafite , Nanofibras , Dispositivos Eletrônicos Vestíveis , Cerâmica , Nitrogênio , Óxidos , Polímeros
6.
Int J Nanomedicine ; 17: 4137-4162, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36118177

RESUMO

Periodontitis is a major threat to oral health, prompting scientists to continuously study new treatment techniques. The nanofibrous membrane prepared via electrospinning has a large specific surface area and high porosity. On the one hand, electrospun nanofibers can improve the absorption capacity of proteins and promote the expression of specific genes. On the other hand, they can improve cell adhesion properties and prevent fibroblasts from passing through the barrier membrane. Therefore, electrospinning has unique advantages in periodontal treatment. At present, many oral nanofibrous membranes with antibacterial, anti-inflammatory, and tissue regeneration properties have been prepared for periodontal treatment. First, this paper introduces the electrospinning process. Then, the commonly used polymers of electrospun nanofibrous membranes for treating periodontitis are summarized. Finally, different types of nanofibrous membranes prepared via electrospinning for periodontal treatment are presented, and the future evolution of electrospinning to treat periodontitis is described.


Assuntos
Nanofibras , Antibacterianos/uso terapêutico , Anti-Inflamatórios , Polímeros , Cicatrização
7.
Carbohydr Polym ; 296: 119847, 2022 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-36087960

RESUMO

Osmotic energy reserves in estuaries, coupled with the ubiquitous solar energy, could be harnessed through emerging nanofluidic membranes to reduce the energy crisis. Herein, we mixed WS2 with high concentration of metal phase and cellulose nanofiber (CNF) to fabricate composite membranes by vacuum filtration. Incorporated CNF as space charge donors increases the ion flux through the enlarged interlayer spacing in the WS2/CNF composite membrane. By simulating seawater and river water, the power density of the composite membrane reached to 1.99 W m-2. Furthermore, due to the photoelectric characteristics of WS2, the composite membrane exhibits photoresponsivity, which generated a photocurrent of 177 nA through illumination. Taking the advantage of the optoelectronic properties of the composite membrane, the power density under illumination is twice than that of the dark state. Based on the results, this material design strategy can enhance the ion transport in nanofluidic membranes for efficient generation of clean energy.


Assuntos
Nanofibras , Celulose , Água Doce , Membranas Artificiais , Osmose
8.
Carbohydr Polym ; 296: 119919, 2022 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-36087974

RESUMO

The degree of polymerization (DP) of cellulose plays an essential role in unlocking the superior mechanical potential of wood cellulose nanofibrils (CNFs). However, severe degradation of cellulose chains during the chemical pulping is a big challenge to obtain CNFs with high DP. In this work, we tend to improve the DP of wood CNFs by significantly preserving the native structure of wood fibers in an industrial method. Wood sticks are first pretreated with hydrothermal treatment to partially remove hemicellulose, thus leading to an increased porous structure that facilitates the penetration of cooking liquid and lignin removal during delignification, and dilute-alkali-sulfate pulping is then employed to obtain wood fibers with highest viscosity average DP (DPV) of nearly 2400. After that, the as-prepared wood fibers with high DP are separated into CNFs with highest average DPV of 1333. Finally, we demonstrate the potential application of wood CNFs with improved DPV in the fabrication of strong and tough isotropic films and macrofibers.


Assuntos
Celulose , Nanofibras , Celulose/química , Lignina/química , Nanofibras/química , Polimerização , Madeira/química
9.
Carbohydr Polym ; 296: 119934, 2022 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-36087985

RESUMO

An enhanced efficiency fertilizer (EEF) is essential for sustainable agriculture, and here, we evaluated cellulose nanofibrils (CNF) as a nutrient carrier dispersed in biodegradable polymeric matrices. CNF were functionalized with negative (CNF-) and positive (CNF+) charges to improve (i) the CNF-nutrient and (ii) the CNF-polymeric matrix interactions. The CNF encapsulated the KNO3 nutrient by spray drying (microcapsules) and then inserted into a poly (hydroxybutyrate)/starch-based matrix by melt-compounding (tablets). These materials were morphologically, structurally, and thermally characterized before and after biodegradation. Nutrient release profiles showed the microcapsules released the nutrients for up to 1 h, while the tablets did for 8 h in water and over 80 days in soil. Tablets with CNF- released NO3- faster than K+, and those with CNF+ behaved inversely. Besides, the biodegradation efficiencies were up to 75 % in 120 days. The CNF charges affected nutrient release and the matrix biodegradation, ensuring the matrices were harmless to the environment.


Assuntos
Celulose , Nanofibras , Cápsulas , Excipientes , Fertilizantes , Nutrientes , Polímeros
10.
Carbohydr Polym ; 296: 119945, 2022 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-36087993

RESUMO

Translation of the high mechanical properties of cellulose nanofibrils (CNFs) to macroscopic fibers represents a great challenge due to difficulties in the assembly of CNFs into well-ordered structures. In this study, we report the ultrastrong and flame-retardant microfibers via the microfluidic wet spinning of phosphorylated cellulose nanofibrils (PCNFs) with high charge content. The macroscopic stress is effectively transferred to the individual PCNFs and results in a Young's modulus of 29 GPa and a tensile strength of 654 MPa. The as-prepared microfibers retain >85 % strength in the wet hydration state, exceeding most natural or synthetic microfibers. Furthermore, glycerol and egg yolk were introduced to the microfibers for enhancing the modulus (31 GPa), strength (865 MPa) and the strain to failure (10.95 %). In addition, the PCNFs microfibers have good flame retardancy. This study expands the potential applications of nanocellulose microfibers in biomedical and flame-retardant materials.


Assuntos
Retardadores de Chama , Nanofibras , Celulose/química , Microfluídica , Nanofibras/química , Resistência à Tração
11.
Carbohydr Polym ; 296: 119994, 2022 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-36088015

RESUMO

Apple xyloglucan (XyG) structural features (molecular weight and building motifs) were studied in relation with the hemicellulose interaction with cellulose nanofiber (CNF) through adsorption isotherm, high performance size exclusion chromatography and high-performance anion exchange chromatography analyses. Up to 75.6 µg of apple XyG adsorbed/mg of CNF. XyG adsorption depended on both Mw and XyG/CNF ratio. The adsorption capacity increased with Mw irrespectively of XyG/CNF ratio. At XyG/CNF ratio > 0.05, the adsorption of high Mw populations (2.0 × 105, 7.9 × 104 g mol-1) gradually ceased, while it kept increasing for low Mw populations (2.6 × 104, 1.2 × 104 g mol-1). The unbranched glucan segments and the galactosylated XLLG motif showed the highest binding affinity to CNF. Most of the XLLG motif was found in "loops and tails", whereas most of the XyG unbranched glucan segments interact directly with CNF.


Assuntos
Malus , Nanofibras , Adsorção , Celulose/química , Glucanos/química , Malus/metabolismo , Peso Molecular , Xilanos
12.
Carbohydr Polym ; 296: 119948, 2022 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-36088028

RESUMO

In this study, cellulose nanofiber (CNF) membranes for water treatment are prepared via in-situ hydrothermal carbonization of glucose in a CNF suspension. The in-situ carbonized CNFs were fabricated into the membranes via dead-end filtration under hydraulic pressure (1 bar). The in-situ carbonized CNF membranes showed high pure water flux (56.25 L·h-1·m-2) without critical flux drop for 12 h of membrane fabrication. The hydrochar chemically bonded with CNF enhanced the durability of CNF during membrane fabrication. Owing to the strong and stable electrostatic interaction between the target dye and hydrochar, the in-situ carbonized membrane also displayed excellent dye rejection for dilute and concentrated solutions, with high selectivity and good reusability. This study provides a successful strategy for fabricating an all-carbohydrate-based high-performance water treatment membrane.


Assuntos
Nanofibras , Purificação da Água , Celulose , Filtração , Membranas Artificiais
13.
Carbohydr Polym ; 296: 119956, 2022 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-36088033

RESUMO

In this study, electrospun Poly(vinyl alcohol)/Chitosan-g-Poly (N-vinyl imidazole) (PVA/CS-g-PNVIM) wound dressing containing Titanium dioxide/Curcumin (CUR) was prepared as a novel wound healing system with multifunctional properties, including wound closure, drug release, and antibacterial activity. The wound dressing nanofibers system's mechanical, structural, and biological properties were investigated using tensile testing, degradation, X-ray diffraction, Scanning electron microscopy, Fourier transformed infrared spectroscopy, drug release, and in vivo studies. The nanofiber dressing showed excellent mechanical and hydrolytic degradation stability. CS-g-PNVIM-based nanofibers showed excellent antibacterial activity against both Escherichia coli and Staphylococcus aureus in just 1 h with 90 % growth inhibition, with no cytotoxicity to normal fibroblast cells. The animal studies showed that the wound healing and tissue regeneration process by CS-g-PNVIM-based nanofibers were faster than the control group and was completed in 14 days. In conclusion, the CS-g-PNVIM-based nanofibers are potentially promising for biocompatible antibacterial wound dressing applications with proper exudate absorption.


Assuntos
Quitosana , Curcumina , Nanofibras , Animais , Antibacterianos/química , Bandagens , Quitosana/química , Curcumina/farmacologia , Escherichia coli , Imidazóis , Nanofibras/química , Titânio
14.
Anal Chim Acta ; 1227: 340308, 2022 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-36089319

RESUMO

Herein, a colorimetric sensing system based on cerium(IV) coordination polymer nanoparticles (Ce(IV)-ATP-Tris CPNs) was proposed for As(V) detection. Ce(IV)-ATP-Tris CPNs show excellent oxidase-like activity, triggering 3,3',5,5'-tetramethylbenzidine (TMB) chromogenic reaction. With addition of ascorbic acid 2-phosphate (AAP) and acid phosphatase (ACP), ACP can hydrolyze AAP to produce antioxidative ascorbic acid (AA), inhibiting TMB chromogenic reaction. After that, introduction of As(V) can inhibit ACP, recovering TMB chromogenic reaction. Therefore, sensitive and selective As(V) detection is achieved. Moreover, Ce(IV)-ATP-Tris CPNs were transformed into cellulose nanofiber (CNF) to form test strip (Ce(IV)-ATP-Tris CPNs/CNF). Inorganic arsenic in rice can be detected by test strip, color of that can be measured by smartphone-integrated colorimetric quantitative analysis platform. Given this, rapid and convenient strip test of inorganic arsenic in rice by using this platform was achieved. Hence, this platform possesses great application potential in the field of inorganic arsenic in rice, even food safety.


Assuntos
Arsênio , Nanofibras , Oryza , Fosfatase Ácida , Trifosfato de Adenosina , Celulose , Colorimetria , Oxirredutases , Smartphone
15.
Wounds ; 34(8): 209-215, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-36108202

RESUMO

INTRODUCTION: Surgical wound healing after Mohs micrographic surgery can be challenging. Achieving an optimal aesthetic outcome is another important consideration, especially for facial lesions. OBJECTIVE: This case series evaluates the use of a novel synthetic nanofiber matrix after Mohs surgery to achieve desired results. MATERIALS AND METHODS: Four patients with NMSCs on the auricular helix underwent Mohs micrographic surgery at a single cancer center. The synthetic nanofiber matrix was applied to the prepared Mohs surgical defect and covered with a dressing. The wounds were evaluated regularly for healing progress, and an additional synthetic nanofiber matrix was applied as needed. RESULTS: Wounds were treated with an average of 1.25 applications ± 0.50 standard deviation of synthetic nanofiber matrix. The initial average wound size was 11.8 cm2. All wounds healed in 7.9 weeks ± 4.2 with excellent aesthetic results, minimal scar formation, and no skin deformity. In cases with exposed structures (cartilage and perichondrium), the synthetic nanofiber material promoted complete closure and healing. No complications were reported. Treatment using a synthetic nanofiber matrix resulted in complete wound healing in all patients. CONCLUSIONS: This study shows the synthetic nanofiber matrix is a viable option for the reconstruction of post-Mohs surgical defects.


Assuntos
Nanofibras , Ferida Cirúrgica , Cicatriz , Humanos , Cirurgia de Mohs , Nanofibras/uso terapêutico , Cicatrização
16.
J Environ Public Health ; 2022: 5852729, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36105514

RESUMO

Herein, we report a novel nanofiber as a humidity sensor applied to autonomous vehicles. We prepared copper oxide nanofibers by electrospinning, characterized the obtained materials by XRD, SEM, and TEM, and fabricated MEMS sensors based on copper oxide nanofibers. The humidity sensitivity performance of the sensor was tested in different humidity environments. We found that the MEMS humidity sensor based on copper oxide nanofibers can detect the change of humidity in the environment over a large humidity range. Its fast response/mixing speed (1 s), good stability, and sensitivity make it to fully adapt to the high speed of the car.


Assuntos
Sistemas Microeletromecânicos , Nanofibras , Veículos Autônomos , Cobre , Óxidos , Relatório de Pesquisa
17.
Anal Biochem ; 656: 114882, 2022 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-36063917

RESUMO

Among many nanomaterials, electrospun carbon nanofibers (CNFs) have become one of the hot spots in nanoscience research because of their interesting physicochemical and biological properties such as large specific surface area, easy functionalization and biocompatibility. Polyacrylonitrile(PAN) has also become the most widely used precursor fiber for CNF manufacturing. In this paper, the latest advances in the synthesis of CNF by electrospinning were reviewed, including using template method, heat treatment, coaxial spinning technology to control the morphology and aperture, as well as the functionalization of electrospinning doped with chemical substances such as heteroatoms, nanoparticles (NPs), carbon nanotubes (CNTs) and grapheme (Gr), in order to further expand its application scope. The application of electrospun CNFs as electrochemical sensing platform for toxic and harmful substances in food and environment was also briefly introduced.


Assuntos
Nanofibras , Nanotubos de Carbono , Nanofibras/química
18.
Chem Pharm Bull (Tokyo) ; 70(9): 628-636, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36047234

RESUMO

Mini-tablets (MTs) contain a small amount of active pharmaceutical ingredients in one small tablet. MTs are advantageous because they can be fine-tuned according to the age and weight of pediatric patients and they are easy for children and the elderly to swallow. However, there are manufacturing concerns such as the difficulty in achieving both hardness and disintegration of a small tablet and it is difficult to keep the tablet weight and drug content consistent in MTs because the mold used for its production is special. In this study, we aimed to determine if an additive such as cellulose nanofibers (CNF), which has been studied in various fields in recent years, could be used to manufacture MTs without difficulties. In this study, an MT was manufactured using a rotary tableting press with a compression force of 2, 5, and 8 kN, and the weight variation, drug content variation, tensile strength, friability, disintegration time, and drug dissolution were evaluated. Of note, the tensile strength of MTs produced with a compression force of ≥5 kN was ≥1.3 MPa, which was comparable to that of an ordinary tablet with an 8 mm diameter and a hardness of ≥30 N. The disintegration time of the MT which was 20-30% CNF was ≤30 s at any compression force. MTs with CNF showed similar disintegration to MTs with other common disintegrants. Therefore, we found that CNF is a functional additive capable of manufacturing MTs by direct powder compression which has both strength and disintegration.


Assuntos
Celulose , Nanofibras , Idoso , Criança , Composição de Medicamentos , Dureza , Humanos , Pós , Comprimidos , Resistência à Tração
19.
Int J Mol Sci ; 23(17)2022 Aug 23.
Artigo em Inglês | MEDLINE | ID: mdl-36076916

RESUMO

Mesothelial cells are specific epithelial cells lining the serosal cavity and internal organs. Nonetheless, few studies have explored the possibility to culture mesothelial cells in a nanostructure scaffold for tissue engineering applications. Therefore, this study aims to fabricate nanofibers from a polycaprolactone (PCL) and PCL/chitosan (CS) blend by electrospinning, and to elucidate the effect of CS on the cellular response of mesothelial cells. The results demonstrate that a PCL and PCL/CS nanofiber membrane scaffold could be prepared with a comparable fiber diameter (~300 nm) and porosity for cell culture. Blending CS with PCL influenced the mechanical properties of the scaffold due to interference of PCL crystallinity in the nanofibers. However, CS substantially improves scaffold hydrophilicity and results in a ~6-times-higher cell attachment rate in PCL/CS. The mesothelial cells maintain high viability in both nanofiber membranes, but PCL/CS provides better maintenance of cobblestone-like mesothelial morphology. From gene expression analysis and immunofluorescence staining, the incorporation of CS also results in the upregulated expression of mesothelial marker genes and the enhanced production of key mesothelial maker proteins, endorsing PCL/CS to better maintain the mesothelial phenotype. The PCL/CS scaffold was therefore chosen for the in vivo studies, which involved transplanting a cell/scaffold construct containing allograft mesothelial cells for mesothelium reconstruction in rats. In the absence of mesothelial cells, the mesothelium wound covered with PCL/CS showed an inflammatory response. In contrast, a mesothelium layer similar to native mesothelium tissue could be obtained by implanting the cell/scaffold construct, based on hematoxylin and eosin (H&E) and immunohistochemical staining.


Assuntos
Quitosana , Nanofibras , Animais , Quitosana/química , Epitélio , Nanofibras/química , Poliésteres/química , Ratos , Engenharia Tecidual/métodos , Tecidos Suporte/química
20.
Nano Lett ; 22(17): 7212-7219, 2022 09 14.
Artigo em Inglês | MEDLINE | ID: mdl-36054509

RESUMO

The ongoing coronavirus (COVID-19) pandemic requires enormous production of facemasks and related personal protection materials, thereby increasing the amount of nondegradable plastic waste. The core material for facemasks is melt-blown polypropylene (PP) fiber. Each disposable facemask consumes ∼0.7 g of PP fibers, resulting in annual global consumption and disposal of more than 1 150 000 tons of PP fibers annually. Herein, we developed a laser-assisted melt-blown (LAMB) technique to manufacture PP nanofibers with a quality factor of 0.17 Pa-1 and significantly reduced the filter's weight. We demonstrated that a standard surgical facemask could be made with only 0.13 g of PP nanofibers, saving approximately 80% of the PP materials used in commercial facemasks. Theoretical analysis and modeling were also conducted to understand the LAMB process. Importantly, nanofibers can be easily scaled up for mass production by upgrading traditional melt blown line with scanning laser-assisted melt-blown (SLAMB).


Assuntos
COVID-19 , Nanofibras , COVID-19/prevenção & controle , Humanos , Lasers , Máscaras , Polipropilenos
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