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1.
Neurol India ; 70(2): 784-787, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35532661

RESUMO

Nasoethmoidal schwannomas are rare lesions and their presentation with intracranial extension is even rarer. Here, a patient presenting with rhinorrhea, epistaxis, and proptosis of left eye was diagnosed with giant nasoethmoidal schwannoma extending to frontal lobe and orbit, which was managed with bifrontal craniotomy with endoscopic transnasal gross total excision. This being predominantly a benign lesion has good prognosis if total excision is achieved.


Assuntos
Estesioneuroblastoma Olfatório , Neurilemoma , Neoplasias Nasais , Craniotomia , Estesioneuroblastoma Olfatório/diagnóstico por imagem , Estesioneuroblastoma Olfatório/cirurgia , Humanos , Cavidade Nasal/diagnóstico por imagem , Cavidade Nasal/patologia , Cavidade Nasal/cirurgia , Neurilemoma/diagnóstico por imagem , Neurilemoma/cirurgia , Neoplasias Nasais/diagnóstico por imagem , Neoplasias Nasais/cirurgia
3.
Medicine (Baltimore) ; 101(10): e29006, 2022 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-35451397

RESUMO

RATIONALE: Neurilemmoma is a benign tumor derived from the Schwann cells of the nerve sheath. The highest incidence of neurilemmoma occurs in the head and neck region; however, the nose and paranasal sinuses are rarely involved. Less than 4% of these tumors involve the nasal cavity and paranasal sinuses. To date, only six cases of nasal vestibule neurilemmoma have been reported. PATIENT CONCERNS: Two patients (a 32-year-old man and a 42-year-old woman) visited our clinic with complaint of a lump in the left nasal vestibule. DIAGNOSIS: Histopathological examination and immunohistochemical staining confirmed a neurilemmoma. INTERVENTIONS: The mass was completely removed via an intranasal approach. OUTCOMES AND LESSONS: Neurilemmoma is easy to overlook because it occurs rarely in the nasal vestibule, but neurilemmoma needs to be considered as a differential diagnosis.


Assuntos
Neurilemoma , Neoplasias Nasais , Adulto , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Cavidade Nasal/patologia , Cavidade Nasal/cirurgia , Neurilemoma/diagnóstico , Neurilemoma/patologia , Neurilemoma/cirurgia , Nariz/patologia , Neoplasias Nasais/diagnóstico , Neoplasias Nasais/patologia , Neoplasias Nasais/cirurgia
4.
Praxis (Bern 1994) ; 111(5): 304-311, 2022 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-35414253

RESUMO

More than a Harmless Cold Abstract. We report on a 54-year-old patient who presented to the general practitioner several times due to a cold with a runny nose and a headache. Despite various therapies the symptoms didn't subside. Further examination showed a nasal NK/T-cell lymphoma stage IV. The patient died despite intensive therapy.


Assuntos
Neoplasias Nasais , Humanos , Pessoa de Meia-Idade , Nariz/patologia , Neoplasias Nasais/patologia , Neoplasias Nasais/terapia
5.
J Craniofac Surg ; 33(2): 588-591, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35385911

RESUMO

OBJECTIVE: Sinonasal tumors invading anterior skull base is difficult to treat in Otorhinolaryngology and Neurosurgery. Treatment requires the collaboration of ear, nose and throat (ENT) and neurosurgeon to remove the tumor completely. This study was to evaluate the outcome of combined technique nasal endoscopic and subfrontal approach in case of sinonasal tumors involving anterior skull base. METHODS: Retrospective cross-sectional study. RESULTS: The study was a cross-sectional study that had taken place at Otorhinolaryngology and Neurosurgery Department of Cho Ray Hospital, Vietnam. All 45 patients were enrolled and underwent the surgery. 71.1% of these cases were malignant tumors. The ratio of sinonasal malignant tumor is squamous cell carcinoma and esthesioneuroblastoma were 24.4% and 11.1%, respectively. All the cases were diagnosed as sinonasal tumor invading anterior skull base and successfully removed by combining nasal endoscopic approach with subfrontal craniotomy. CONCLUSIONS: The combined nasal endoscopic with subfrontal craniotomy for resection nasoethmoid tumor invading the brain show a good result. This technique is an important adjunct that contribute to the treatment of anterior skull base tumor involving the brain.


Assuntos
Neoplasias Nasais , Neoplasias dos Seios Paranasais , Neoplasias da Base do Crânio , Craniotomia/métodos , Estudos Transversais , Endoscopia/métodos , Humanos , Neoplasias Nasais/cirurgia , Neoplasias dos Seios Paranasais/diagnóstico por imagem , Neoplasias dos Seios Paranasais/patologia , Neoplasias dos Seios Paranasais/cirurgia , Estudos Retrospectivos , Base do Crânio/patologia , Base do Crânio/cirurgia , Neoplasias da Base do Crânio/diagnóstico por imagem , Neoplasias da Base do Crânio/patologia , Neoplasias da Base do Crânio/cirurgia
6.
Can Vet J ; 63(4): 386-390, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35368390

RESUMO

Nasal planectomy is recommended in cases of squamous cell carcinoma of the nasal planum in dogs and can be curative if excision is complete. Due to the noticeable alteration in appearance inherent in nasal planectomy, several techniques are described for reconstruction. The goal of this study is to report the complication rate and owner satisfaction following nasal planectomy with repair by direct mucocutaneous apposition compared to other reported reconstruction techniques meant to be more cosmetic. Eleven dogs were identified that underwent nasal planectomy with reconstruction via mucocutaneous apposition. Complications were noted in 8/11 dogs: all minor. All dogs underwent CT preoperatively for surgical planning. Complete excision was noted in 10/11 cases. Results suggest that direct mucocutaneous apposition is a viable surgical option for reconstruction following nasal planectomy with favorable major complication rates and owner satisfaction. In addition, direct mucocutaneous apposition for closure following nasal planectomy should be considered, especially in cases in which bone is not resected, because of low complication rates and reasonable cosmetic outcome.


Résultat et taux de complications de la planectomie nasale reconstruite avec apposition cutanéomuqueuse directe. La planectomie nasale est recommandée en cas de carcinome épidermoïde du planum nasal chez le chien et peut être curative si l'exérèse est complète. En raison de l'altération notable de l'apparence inhérente à la planectomie nasale, plusieurs techniques sont décrites pour la reconstruction. Le but de cette étude est de rapporter le taux de complications et la satisfaction du propriétaire suite à une planectomie nasale avec réparation par apposition cutanéo-muqueuse directe par rapport aux autres techniques de reconstruction rapportées censées être plus esthétiques. Onze chiens ont été identifiés ayant subi une planectomie nasale avec reconstruction via apposition cutanéo-muqueuse. Des complications ont été notées chez 8/11 chiens : toutes mineures. Tous les chiens ont subi une tomodensitométrie préopératoire pour la planification chirurgicale. Une exérèse complète a été notée dans 10/11 cas. Les résultats suggèrent que l'apposition cutanéo-muqueuse directe est une option chirurgicale viable pour la reconstruction après une planectomie nasale avec des taux de complications majeures favorables et une satisfaction du propriétaire. De plus, l'apposition mucocutanée directe pour la fermeture après une planectomie nasale doit être envisagée, en particulier dans les cas où l'os n'est pas réséqué, en raison du faible taux de complications et du résultat esthétique raisonnable.(Traduit par Dr Serge Messier).


Assuntos
Carcinoma de Células Escamosas , Doenças do Cão , Neoplasias Nasais , Procedimentos Cirúrgicos Reconstrutivos , Animais , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/cirurgia , Carcinoma de Células Escamosas/veterinária , Doenças do Cão/cirurgia , Cães , Nariz , Neoplasias Nasais/patologia , Neoplasias Nasais/cirurgia , Neoplasias Nasais/veterinária , Procedimentos Cirúrgicos Reconstrutivos/veterinária
7.
Head Neck ; 44(6): 1356-1367, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35355362

RESUMO

BACKGROUND: Despite adjuvant radiotherapy, rates of recurrences of endoscopically operated nasal intestinal-type adenocarcinomas (ITAC) have not been improved in successive series. To better understand how to improve local control, we aimed to investigate the site of local recurrences of ITACs. METHODS: Retrospective study in a reference center in sinonasal malignancies. For all patients with a local recurrence, radiotherapy plans were retrieved and compared to the delineation of local recurrences. RESULTS: Of 63 patients, 54 underwent adjuvant radiotherapy of which 14 (25.9%) had a local recurrence. Eleven of them had their onset in an optimally irradiated area. Difficulty to dissect the cribriform plate and/or the lateral lamina was reported for 11 patients with local recurrences in the operative reports (p <0.0001). CONCLUSIONS: Most of recurrences arose in an optimally irradiated area. A close cooperation between surgeons and radiotherapists is required to define areas at risk and adapt treatment.


Assuntos
Adenocarcinoma , Neoplasias Nasais , Adenocarcinoma/patologia , Adenocarcinoma/radioterapia , Adenocarcinoma/cirurgia , Humanos , Recidiva Local de Neoplasia/patologia , Neoplasias Nasais/patologia , Neoplasias Nasais/radioterapia , Neoplasias Nasais/cirurgia , Radioterapia Adjuvante , Recidiva , Estudos Retrospectivos
9.
Acta Med Okayama ; 76(1): 93-98, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35237005

RESUMO

A 66-year-old man underwent multimodal treatment for olfactory neuroblastoma (ONB). When he was 72 years old, a cystic intracranial lesion without accumulation on fluorine-18-fluorodeoxyglucose positron emission tomography was detected. Surgical resection was performed when the patient was 73 years old. The pathological examination revealed recurrence of ONB, and the patient underwent focal irradiation. At age 81, he presented with a second recurrence in the right occipital lobe with radiological and pathological findings similar to the prior recurrence. This case suggests that pathological confirmation should be considered in cases with atypical radiological findings following the treatment of ONB.


Assuntos
Estesioneuroblastoma Olfatório/diagnóstico por imagem , Cavidade Nasal/patologia , Recidiva Local de Neoplasia/diagnóstico por imagem , Neoplasias Nasais/diagnóstico por imagem , Tomografia por Emissão de Pósitrons , Idoso , Idoso de 80 Anos ou mais , Radioisótopos de Flúor , Fluordesoxiglucose F18 , Humanos , Masculino , Tomografia Computadorizada por Raios X
11.
Clin Neuropathol ; 41(3): 114-121, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35142285

RESUMO

Although angiogenesis plays an important role in tumor growth and invasion, its role in the progression of olfactory neuroblastoma (ONB) has rarely been published. The aim of the present research was to analyze the prognostic role of microvessel density (MVD) in ONB and its association with clinicopathological parameters. 70 ONB cases were assessed for immunohistochemical expression of CD31, CD34, CD105, VEGF, and VEGFR2. The expression of CD105-MVD was negatively associated with histological grade and tumor Kadish stage, and its expression was positively correlated with the expression of VEGF/VEGFR2. Low expression of CD105-MVD and high tumor histological grade were strongly associated with poor survival. Thus, CD105-MVD was demonstrated to be a valuable independent prognostic indicator for ONB. MVD is expected to be useful as an important marker to distinguish tumor histological grade.


Assuntos
Estesioneuroblastoma Olfatório , Neoplasias Nasais , Antígenos CD/metabolismo , Biomarcadores Tumorais/metabolismo , Endoglina , Humanos , Densidade Microvascular , Cavidade Nasal/metabolismo , Cavidade Nasal/patologia , Neovascularização Patológica/metabolismo , Neovascularização Patológica/patologia , Neoplasias Nasais/diagnóstico , Prognóstico , Receptores de Superfície Celular/metabolismo , Fator A de Crescimento do Endotélio Vascular/metabolismo
13.
Ann Plast Surg ; 88(1s Suppl 1): S106-S109, 2022 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-35225856

RESUMO

BACKGROUND: Extensive nasal defects after resection of a malignancy are a challenge for all plastic surgeons. Nasal composite tissue defects have to be reconstructed with multiple staging surgeries. A paramedian pedicled forehead flap and free tissue transfer can be used for lining and skin replacement at different stages. In general, free tissue transfer is used for nasal lining and nasal floor reconstruction at the preliminary stage. Several weeks or months later, a paramedian pedicled forehead flap is used to replace the skin. Intermediate stages will also be necessary, and therefore the total therapeutic course is very long. AIM AND OBJECTIVES: The aim of this study was to report the simultaneous use of a paramedian pedicle forehead flap and a free medial sural artery perforator (MSAP) flap to reconstruct a composite nasal defect after wide excision of squamous cell carcinoma. PATIENT: In 2015, a 57-year-old woman with squamous cell carcinoma of the nose underwent tumor wide excision, which caused a composite defect involving multiple nasal subunits (partial tip, dorsum, right sidewall, right ala subunits). She received both a pedicled paramedian forehead flap to replace the skin and an MSAP flap to reconstruct the lining during the same procedure. At the intermediate stage 4 weeks later, the pedicled forehead flap was elevated and tailored. Then, a further 4 weeks later, flap division was performed. RESULTS: The patient received a total of 3 surgical procedures to reconstruct the composite defects of multiple nasal subunits. Nasal reconstruction was done within 2 months. The patient was satisfied with the aesthetic appearance and functional outcome. CONCLUSIONS: Simultaneous paramedian pedicle forehead and free flap reconstruction can provide an effective solution for composite nasal defects. Satisfactory functional and aesthetic results can be achieved.


Assuntos
Neoplasias Nasais , Retalho Perfurante , Rinoplastia , Artérias/cirurgia , Feminino , Testa/cirurgia , Humanos , Pessoa de Meia-Idade , Nariz/cirurgia , Neoplasias Nasais/cirurgia , Retalho Perfurante/cirurgia , Rinoplastia/métodos
15.
J Vet Intern Med ; 36(2): 733-742, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35188694

RESUMO

BACKGROUND: The safety and efficacy of stereotactic body radiation therapy (SBRT) in the treatment of localized nasal lymphoma in cats has not been described. HYPOTHESIS: Stereotactic body radiation therapy with or without adjuvant chemotherapy is an effective and well-tolerated treatment for localized nasal lymphoma in cats. ANIMALS: Thirty-two client owned cats referred to Colorado State University for the treatment of nasal lymphoma. METHODS: Retrospective study of cats treated with SBRT between 2010 and 2020 at Colorado State University. Diagnosis of nasal lymphoma was obtained via cytology or histopathology. Signalment, radiation protocol, concurrent treatments, adverse effects, and survival were recorded. RESULTS: Progression free survival was 225 days (95% CI 98-514) and median survival time (MST) was 365 days (95% CI 123-531). No significant difference in survival was identified between cats that received 1 versus greater than 1 fraction (MST 427 vs. 123 days, P = 0.88). Negative prognostic factors included cribriform lysis (MST 121 vs. 876 days, P = 0.0009) and intracalvarial involvement (MST 100 vs. 438 days, P = 0.0007). Disease progression was noted in 38% (12/32), locally in 22% (7/32), and systemically in 16% (5/32). No cats developed acute adverse effects. Ten cats developed late adverse effects: keratitis/keratitis sicca (n = 2), alopecia (n = 4), and leukotrichia (n = 4). Twenty-four cats (75%) had signs consistent with chronic rhinitis. CONCLUSIONS: SBRT is effective and well tolerated for treating localized nasal lymphoma in cats. Outcomes for cats with lower stage disease (canine modified Adam's stage 3 and lower) are comparable to historic data of cats treated with fractionated radiation therapy.


Assuntos
Doenças do Gato , Doenças do Cão , Linfoma , Neoplasias Nasais , Radiocirurgia , Animais , Doenças do Gato/tratamento farmacológico , Gatos , Doenças do Cão/patologia , Cães , Humanos , Linfoma/tratamento farmacológico , Linfoma/radioterapia , Linfoma/veterinária , Neoplasias Nasais/radioterapia , Neoplasias Nasais/veterinária , Radiocirurgia/efeitos adversos , Radiocirurgia/veterinária , Estudos Retrospectivos , Resultado do Tratamento
16.
Oral Oncol ; 127: 105768, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35189583

RESUMO

Inverted sinonasal papilloma is an infrequent tumor that mostly affects the elder group of 40-50 yr. This tumor is distinguished from other sinonasal tumors by three characteristics: a high rate of recurrence, carcinomatous changes, and a high potential for local destruction. In 40% of cases of inverted sinonasal papilloma showed an association with the human papillomavirus and considered as the main etiological agent. Here, we present a case of a 36-year-old male presented with pus discharge from the right upper back teeth region in the past 1 year. Correlating with clinical, radiographical features, a diagnosis of the Inverted sinonasal papilloma.


Assuntos
Neoplasias Nasais , Papiloma Invertido , Neoplasias dos Seios Paranasais , Adulto , Idoso , Humanos , Masculino , Recidiva Local de Neoplasia , Neoplasias Nasais/diagnóstico por imagem , Papiloma Invertido/diagnóstico por imagem , Papiloma Invertido/patologia , Papillomaviridae , Neoplasias dos Seios Paranasais/patologia
17.
Am J Case Rep ; 23: e934149, 2022 Feb 04.
Artigo em Inglês | MEDLINE | ID: mdl-35115482

RESUMO

BACKGROUND Inverted papilloma is a benign epithelial lesion of the nasal cavities. Although commonly encountered in clinical practice, it rarely presents with extensive ossification and few cases have been described in the literature. CASE REPORT Herein, we describe the case of a 51-year-old man who presented to clinical attention for persistent right nasal obstruction. Magnetic resonance imaging (MRI) and computed tomography (CT) scans of the facial bones showed a lobated lesion with ossification occupying most of the right nasal cavity. The lesion was removed by endoscopic sinus surgery, leaving the surrounding bone structures intact. On pathological examination, mature bone tissue was found within an inverted papilloma. The pathologist contacted the surgeon, who confirmed that no healthy bone tissue was removed during the procedure. Therefore, a diagnosis of inverted papilloma with ossification could be made without the use of ancillary techniques. CONCLUSIONS Inverted papilloma with ossification is a common lesion with a rare feature. Our report investigates the diagnostic difficulties of a paradigmatic case, highlighting the importance of multidisciplinary teamwork in reaching the final diagnosis.


Assuntos
Neoplasias Nasais , Papiloma Invertido , Neoplasias dos Seios Paranasais , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Nasais/diagnóstico por imagem , Neoplasias Nasais/cirurgia , Osteogênese , Papiloma Invertido/cirurgia , Neoplasias dos Seios Paranasais/diagnóstico por imagem , Neoplasias dos Seios Paranasais/cirurgia , Tomografia Computadorizada por Raios X
18.
Ann Chir Plast Esthet ; 67(1): 26-34, 2022 Feb.
Artigo em Francês | MEDLINE | ID: mdl-35120781

RESUMO

INTRODUCTION: The aesthetic reconstruction of full thickness defects of the entire ala is difficult because of its complex tridimensional anatomy. The triplan reconstruction of this unit which includes: -a lining with a mucosal flap, -a sculptured cartilage framework imitating the anatomy of the opposite ala -and a skin coverage by an immediate defatted forehead flap, gives regularly a very good aesthetic results, superior to the ones obtained by other techniques. PATIENTS AND METHODS: From may 2008 to December 2020, 26 patients aged between 49 and 78 years old have benefited from this triplan aesthetic reconstruction after an excision of evolved basal cell carcinomas interesting the ala unit. The defects resulting were located in the entire ala with slight extension to the adjacent units. In all cases, the lining was reconstructed by the BURGET'S homolateral septal mucosal flap. The shape of the ala was obtained by a precise sculpture of conqual cartilage, taking the opposite ala as the model. The cutaneous coverage was provided by a paramedian forehead flap tailored exactly to the defect's size and immediately defatted. RESULTS: With a mean follow up of 8 years, all the reconstructed ala were quasi symmetrical to the opposite ones with a very good shape of the new nostrils. No complications and no tumoral recurrence are reported. CONCLUSION: This triplan reconstruction of the entire ala's defects is really aesthetic and gives a natural look for the lower third of the nose.


Assuntos
Carcinoma Basocelular , Neoplasias Nasais , Rinoplastia , Neoplasias Cutâneas , Idoso , Carcinoma Basocelular/cirurgia , Estética , Humanos , Pessoa de Meia-Idade , Recidiva Local de Neoplasia , Nariz/cirurgia , Neoplasias Nasais/cirurgia , Neoplasias Cutâneas/cirurgia
19.
BMJ Case Rep ; 15(2)2022 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-35131785

RESUMO

Bleeding nasal mass in adolescent boys has customarily been attributed to Juvenile nasopharyngeal angiofibroma. However, little is known regarding the extranasopharyngeal origin of angiofibroma, as highlighted in this case report of a 15-year-old boy who presented with recurrent epistaxis and nasal obstruction. On constructing a working diagnosis of nasal haemangioma, the patient was taken up for endoscopic excision under general anaesthesia. Intraoperative endoscopic findings and histopathological examination revealed the diagnosis of middle turbinate angiofibroma, which is an extremely rare extranasopharyngeal angiofibroma. Consequently, this represents the third described case of a juvenile angiofibroma arising from the middle turbinate.


Assuntos
Angiofibroma , Obstrução Nasal , Neoplasias Nasofaríngeas , Neoplasias Nasais , Adolescente , Angiofibroma/diagnóstico por imagem , Angiofibroma/cirurgia , Humanos , Masculino , Obstrução Nasal/etiologia , Obstrução Nasal/cirurgia , Neoplasias Nasofaríngeas/diagnóstico por imagem , Neoplasias Nasofaríngeas/cirurgia , Neoplasias Nasais/diagnóstico por imagem , Neoplasias Nasais/cirurgia , Conchas Nasais/diagnóstico por imagem , Conchas Nasais/cirurgia
20.
Artigo em Chinês | MEDLINE | ID: mdl-35193341

RESUMO

Objective:To explore the value of nasal endoscopy assisting combined with transoral approach in resection of the carcinoma of the palate with the nasal cavity and sinuses invaded. Methods:A retrospective analysis of 21 patients with a primary malignant tumors of the palate was performed. Preoperative nasal endoscopy and CT and MRI scan showed that the primary tumors invading the nasal cavity and sinuses in all patients or skull base with varying degrees. All patients were treated by nasal endoscopic assisting combined with transoral approach. Postoprational adjuvant radiotherapy or concurrent chemoradiotherapy was performed according to pathological types and clinical stage. Postoperative complications, all-tumor resection rate, local control rate and 5-year survival rate were analyzed statistically. Results:The combined approach was successfully performed in all patients. En bloc resection was carried out in 18 patients by this combined approach and surgical margins were free of carcinoma. The median follow-up period was 60 months. All patients had good nasal ventilation function and no epiphora in postoperation, and the overall local control rate of primary site was 85.7%, overall 5-year survival rate was 76.2%. Conclusion:Nasal endoscopy assisting combined with transoral approach is an effective method for the resection of palate malignant tumors invading the nasal cavity and sinuses. It is convenient for en bloc resection and local control of primary lesions. It is beneficial to preserve the function of nasal cavity and sinuses, which is in line with the principle of functional surgery.


Assuntos
Carcinoma de Células Escamosas , Neoplasias Nasais , Carcinoma de Células Escamosas/patologia , Endoscopia/métodos , Humanos , Cavidade Nasal/patologia , Cavidade Nasal/cirurgia , Neoplasias Nasais/patologia , Neoplasias Nasais/cirurgia , Palato , Estudos Retrospectivos
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