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1.
Food Chem ; 341(Pt 2): 128259, 2021 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-33068847

RESUMO

The present work aimed to characterize the nanoemulsion of anise seed extract and to compare its efficacy with the bulk extract against pathogenic bacteria. The anise seeds extract was prepared by cold solvent extraction method using ethanol. Nanoemulsion of anise extract was formulated using ultrasound assisted method and analyzed using high-performance liquid chromatography (HPLC), fourier transform infrared spectroscopy (FTIR) and UV-visible spectrophotometry. The antimicrobial activity of the nanoemulsion was tested against seven foodborne pathogenic bacterial species. Results showed that the extract contained anethole (37%), naringenin (21%), and taxifolin (13%) as the major phytochemical components. The average droplet size of the nanoemulsion droplets was measured by dynamic light scattering (DLS) and confirmed by transmission electron microscope to be about 400 nm. Anise extract nanoemulsion showed higher antimicrobial activity against most of the tested pathogens. Anise extract nanoemulsion performed better than bulk extract as an antimicrobial agent against some foodborne pathogenic bacteria.


Assuntos
Anti-Infecciosos/química , Emulsões/química , Pimpinella/química , Extratos Vegetais/química , Derivados de Alilbenzenos , Anisóis/química , Anisóis/farmacologia , Anti-Infecciosos/farmacologia , Difusão Dinâmica da Luz , Flavanonas/química , Flavanonas/farmacologia , Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Testes de Sensibilidade Microbiana , Nanoestruturas/química , Pimpinella/metabolismo , Sonicação , Espectroscopia de Infravermelho com Transformada de Fourier
2.
Food Chem ; 344: 128574, 2021 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-33218855

RESUMO

Application of synthetic preservatives to control the contamination of stored food commodities with aflatoxin B1 causing considerable loss in nutritional value is a major challenge. However, employment of essential oils for protecting food commodities is much limited due to high volatility, and increased susceptibility to oxidation. Therefore, objective of the present investigation was encapsulation of Pimpinella anisum essential oil in chitosan nanobiopolymer (CS-PAEO-Nm) to improve its bioefficacy, and sensorial suitability for application in food system. The synthesized CS-PAEO-Nm was characterized through SEM, FTIR, and XRD and evaluated for improved biological activity. The CS-PAEO-Nm exhibited improved antifungal (minimum inhibitory concentration = 0.08 µL/mL) and antiaflatoxigenic (minimum aflatoxin inhibitory concentration = 0.07 µL/mL) activities. CS-PAEO-Nm treatment significantly inhibited ergosterol, enhanced leakage of ions and induced impairment in defense enzymes (p < 0.05). In situ minerals and macronutrient preservation, and acceptable sensorial characteristics suggested possible recommendation of nanoencapsulated PAEO as potential safe green food preservative.


Assuntos
Aflatoxina B1/antagonistas & inibidores , Fungos/fisiologia , Nanoestruturas/química , Valor Nutritivo/efeitos dos fármacos , Óleos Voláteis/química , Óleos Voláteis/farmacologia , Pimpinella/química , Antifúngicos/química , Antifúngicos/farmacologia , Quitosana/química , Conservantes de Alimentos/química , Conservantes de Alimentos/farmacologia , Fungos/efeitos dos fármacos , Testes de Sensibilidade Microbiana
3.
Food Sci Technol Int ; 27(2): 123-134, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32611207

RESUMO

The present study aimed to develop a novel active edible film based on gelatin incorporated with 0, 0.3, 0.6, and 0.9% w/w anise essential oil as a natural preservative and investigate the shelf life extension potential of chicken fillets during 12 days of refrigerated storage. The chicken fillets were wrapped with the essence-free and anise essential oil-loaded gelatin films, and microbial counts, chemical and sensory tests were surveyed during chilled storage. Results showed that aerobic mesophilic bacteria and Pseudomonas spp counts significantly decreased at all levels of anise essential oil during the first week of storage, while psychrotrophs, yeasts, and molds numbers began to reduce at concentrations of 0.6 and 0.9% from day 6. The using of anise essential oil caused a significant decrease of chemical parameters of chicken fillets, and the values of pH, peroxide, thiobarbituric acid reactive substance, and total volatile basic-nitrogen reached from 7.42, 5.7 meq/kg, 2.21 mg malondialdehyde/kg, and 24.94 mg N/100 g for the essence-free wrapped samples to 4.8, 6.35 meq/kg, 1.73 mg malondialdehyde/kg, and 18.78 mg N/100 g for the ones wrapped with 0.9% anise essential oil-loaded gelatin films at the end of storage day. In conclusion, application of gelatin films loaded with 0.6 and 0.9% anise essential oil can be advised for wrapping chicken fillets to prolong the shelf life for at least one week.


Assuntos
Bactérias , Microbiologia de Alimentos , Gelatina , Carne , Óleos Voláteis , Pimpinella , Animais , Bactérias/efeitos dos fármacos , Galinhas , Microbiologia de Alimentos/métodos , Embalagem de Alimentos , Carne/microbiologia , Carne/normas , Óleos Voláteis/farmacologia , Pimpinella/química , Paladar/efeitos dos fármacos
4.
J Oleo Sci ; 69(11): 1367-1371, 2020 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-33055447

RESUMO

In this study, bioactive lipid components such as fatty acid composition, tocopherol and total phenolics content and antioxidant activity of few wild plant seed extracts were determined. The oil contents of seed samples changed between 3.75 g/100 g (Onobrychis viciifolia Scop) and 17.94 g/100 g (Pimpinella saxifrage L.). While oleic acid contents of seed oils change between 10.4% (Trifolium repens) and 29.5% (Onobrychis viciifolia Scop), linoleic acid contents of oil samples varied from 16.3% (Onobrychis viciifolia Scop) and 64.2% (Trifolium repens) (p < 0.05). While α-tocopherol contents of oil samples change between 2.112 (Pimpinella saxifrage L.) and 228.279 mg/100 g (Trifolium pratense), É£-tocopherol contents ranged from 0.466 (Phleum pratense) to 67.128 mg/100 g (Onobrychis viciifolia Scop). Also, α-tocotrienol contents of Onobrychis viciifolia Scop and Phleum pratense were 30.815 and 23.787 mg/100 g, respectively. Results showed some differences in total phenol contents and antioxidant activity values of extracts depending on plant species. The present study indicates that this seed oils are rich in fatty acid and tocopherol.


Assuntos
Antioxidantes/análise , Fabaceae/química , Ácidos Graxos/análise , Phleum/química , Pimpinella/química , Óleos Vegetais/química , Sementes/química , Tocoferóis/análise , Trifolium/química , Ácido Oleico/análise
5.
Molecules ; 25(20)2020 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-33092276

RESUMO

The insecticidal activity is the result of a series of complex interactions between toxic substances as ligands and insect's enzymes as targets. Actually, synthetic insecticides used in pest control programs are harmful to the environment and may affect non-target organisms; thus, the use of natural products as pest control agents can be very attractive. In the present work, the toxic effect of aniseed (Pimpinella anisum L.) essential oil (EO) and its nanoemulsion (NE) against the red flour beetle Tribolium castaneum, has been evaluated. To assess the EO mode of action, the impact of sub-lethal concentrations of aniseed EO and NE was evaluated on enzymatic and macromolecular parameters of the beetles, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein, total lipids and glucose. Finally, a molecular docking study was conducted to predict the mode of action of the major EO and NE components namely E-anethole, Limonene, alpha-himalachalene, trans-Verbenol and Linalool at binding site of the enzymes AST and ALT. Herein, the binding location of the main compounds in both proteins are discussed suggesting the possible interactions between the considered enzymes and ligands. The obtained results open new horizons to understand the evolution and response of insect-plant compounds interactions and their effect predicted at the molecular levels and side effects of both animal and human.


Assuntos
Monoterpenos/química , Óleos Voláteis/química , Pimpinella/química , Tribolium/efeitos dos fármacos , Alanina Transaminase/antagonistas & inibidores , Alanina Transaminase/química , Animais , Aspartato Aminotransferases/antagonistas & inibidores , Aspartato Aminotransferases/química , Emulsões/química , Emulsões/farmacologia , Interações Ervas-Drogas , Humanos , Simulação de Acoplamento Molecular , Monoterpenos/farmacologia , Nanoestruturas/química , Óleos Voláteis/farmacologia
6.
J Nutr Sci Vitaminol (Tokyo) ; 66(4): 325-330, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32863305

RESUMO

In many countries, excessive consumption of sodium chloride (salt) has become a serious social problem and reducing salt has been required. Herbs have been reported to enhance the saltiness of food; however, few studies have focused on the numerical evaluation of the degree of saltiness enhancement by herbs. The purpose of this study was to quantify the degree of saltiness enhancement by herbs via human sensory evaluation using a visual analog scale (VAS). The sensory evaluation was conducted on 69 students who were able to arrange the five different saline concentrations in order. The sensory salt concentration of herb-added 0.4 wt% saline solutions were perceived in comparison with the saltiness of 0.2 to 0.6 wt% reference saline solutions. The results were recorded by an arrow on a VAS. Hot-water extracts of the herbs basil, rosemary, parsley, anise, and oregano were used. The sensory salt concentration of a 0.175 wt% herb-added saline was equivalent to the actual salt concentration (0.4 wt%). However, the sensory salt concentrations of salines with 0.35 wt% herb extracts were significantly higher (p<0.001). There were no significant differences in the saltiness-enhancing effects depending on the species of, preference for, and familiarity with a particular herb. It was estimated that the addition of 0.35 wt% herb extracts enhanced the salty taste of the saline by 1.13 to 1.22 times.


Assuntos
Cloreto de Sódio na Dieta , Especiarias , Percepção Gustatória , Feminino , Humanos , Masculino , Ocimum basilicum , Origanum , Petroselinum , Pimpinella , Rosmarinus , Adulto Jovem
7.
Plant Biol (Stuttg) ; 22(6): 1092-1101, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32810916

RESUMO

The recovery of altered or damaged ecosystems demands large-scale reintroductions of seeds. In the past, ecological restoration in Germany was carried out with non-local seeds of naturally occurring species. We here analysed whether the genetic pattern of the introduced non-local seeds (R = restored) of Pimpinella saxifraga are still detectable several years after application and whether the phenotype differs from that of the regional gene pool (I = indigenous) of the species. We collected material from individuals of R and I sites, conducted a common garden experiment and tested for genetic, morphological and phenotypic differences. In a cutting experiment we investigate treatment effects on indigenous and restored populations. At all investigated sites we only found P. saxifraga individuals with comparatively similar genome sizes. The population genetic analysis revealed two large and quite distinct molecular clusters, separating indigenous and restored individuals along the first axis. None of the vegetative, but two of the reproductive fitness parameters differed between individuals of the R and I sites. Cutting always had a significant influence on all analysed vegetative and reproductive fitness parameters, regardless of the individuals' origin. The effects of mowing always mask origin-specific characteristics, which then disappear. Genotypic coexistence reduces the availability of niches for the local genotype and may eventually lead to genotypic competition or introgression. We therefore recommend not to use non-local genotypes of this species in the region. Instead, we recommend using the genetically diverse local genotypes of P. saxifraga for restoration purposes.


Assuntos
Recuperação e Remediação Ambiental , Pimpinella , Ecossistema , Genótipo , Alemanha , Fenótipo , Pimpinella/genética , Tempo
8.
Animal ; 14(12): 2642-2651, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32618544

RESUMO

Utilization of low-input feed resources rich in plant bioactive compounds is a promising strategy for modulating the fatty acid profile in ruminant products. They manipulate microbes involved in rumen biohydrogenation and increase the accumulation of desirable fatty acids at the tissue level. Therefore, the present study was undertaken to assess the effect of dietary supplementation of aniseed straw and eucalyptus leaves on growth performance, carcass traits and fatty acid profile of finisher lambs. Thirty-six Malpura hogget were divided into three treatment groups of 12 each, reared individually in pen (1.6 m × 1.1 m) and fed ad libitum complete feed blocks made up of 55 parts concentrate, 5 parts molasses and 40 parts roughage. Roughage in control (Con) was 20 parts each of ardu (Ailanthus excelsa) leaves and oat (Avena sativa) straw. In test diets, that is, Con-as and Con-el, 10% aniseed (Pimpinella anisum) straw and Eucalyptus rudis leaves, respectively, were added by replacing 5% each of oat straw and eucalyptus leaves. The lambs were weighed weekly; and at the end of 3 months of feeding trial, the lambs were slaughtered to study the carcass traits, composition and product evaluation. Average daily gain (ADG) and DM intake (DMI) was higher (P < 0.05) in Con-as compared to Con and Con-el, while ADG and feed conversion ratio decreased (P < 0.05) by 29.4% and 36.4%, respectively, in Con-el compared to Con. Carcass traits showed lower (P < 0.05) loin eye area and chilling loss in the Con-el group compared to the Con-as and Con, and the total carcass fat compared to Con-as. However, the keeping quality of meat improved in both Con-as and Con-el which was reflected by lower (P < 0.05) thiobarbituric acid-reactive substances values. Nuggets prepared from Con and Con-as meat had superior (P < 0.05) sensory attributes with an overall palatability. Fatty acid profile of longissimus thoracis muscle showed lower (P < 0.05) atherogenic and thrombogenic indices in Con-as and higher (P < 0.05) in Con-el group. Moreover, in Con-as group, the proportion of C16:0 was lower (P < 0.05) and C18:3n-3 was higher (P < 0.05), but no effect was observed on the amount of conjugated linoleic acid (CLA; C18:2 c9t11). In case of adipose tissue, the content of CLA was higher (P < 0.05), and the ratio of n-6:n-3 was more nearer to desirable levels in Con-as group. Therefore, it can be concluded that aniseed straw is a promising feed supplement compared to eucalyptus leaves for improving meat quality and fatty acid profile in lambs.


Assuntos
Eucalyptus , Pimpinella , Ração Animal/análise , Animais , Composição Corporal , Dieta/veterinária , Suplementos Nutricionais , Ácidos Graxos , Carne/análise , Folhas de Planta , Ovinos
9.
J Ethnopharmacol ; 254: 112730, 2020 May 23.
Artigo em Inglês | MEDLINE | ID: mdl-32145331

RESUMO

ETHNOPHARMACOLOGY RELEVANCE: Pimpinella anisum is a well-known traditional medicinal herb which has been used in folk medicine as an antiulcer, anticancer, antibacterial and as a muscle relaxant. AIM OF THE STUDY: This study was performed to explore the modulatory effects of Pimpinella anisum on term-pregnant rat uterine contractility and to investigate its possible underlying mechanisms. MATERIAL AND METHODS: Intact uterine strips without endometrial layer were isolated from female term-pregnant Wistar rats (22 days of gestation) and mounted in a tissue bath apparatus for in vitro isometric force recording. The effects of different concentrations of Pimpinella anisum extract (PAE) (1, 3, 5, and 7 mg/mL) were examined on uterine contractions generated spontaneously or induced with oxytocin (5 nmol/L), Bay K8644 (1 µmol/L), and carbachol (10 µmol/L). In some experiments, PAE was applied on depolarized myometrium in the presence of high-KCl solution (60 mmol/L). The effect on Ca2+ release was also examined. RESULTS: Application of PAE significantly reduced uterine contractions generated spontaneously or induced with oxytocin, Bay K8644, and carbachol in a concentration-dependent manner (n = 7; P < 0.01). In depolarized myometrium, PAE significantly reduced the tonic force induced by high-KCl solution (n = 7; P < 0.01). PAE prevented oxytocin-induced transient contraction in the entire absence of external calcium (n = 7; P < 0.01). CONCLUSION: The present findings demonstrate the potentials of PAE to relax pregnant uterine contractions possibly by blocking Ca2+ entry via L-type calcium channels and inhibiting Ca2+ release from the internal store. The tocolytic effects of PAE may be a potential adjuvant against strong premature uterine contractions which threaten early pregnancy although clinical studies are required.


Assuntos
Pimpinella , Extratos Vegetais/farmacologia , Tocolíticos/farmacologia , Contração Uterina/efeitos dos fármacos , Éster Metílico do Ácido 3-Piridinacarboxílico, 1,4-Di-Hidro-2,6-Dimetil-5-Nitro-4-(2-(Trifluormetil)fenil) , Animais , Carbacol , Feminino , Ocitocina , Cloreto de Potássio , Gravidez , Ratos Wistar , Útero/efeitos dos fármacos , Útero/fisiologia
10.
Folia Morphol (Warsz) ; 79(3): 489-502, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31724151

RESUMO

BACKGROUND: The present study aimed to investigate, for the first time to the best of our knowledge, the effect of aqueous anise extract on the pancreatic damage in the streptozotocin (STZ)-induced diabetic rat model with referral to some of its underlying mechanisms. MATERIALS AND METHODS: Forty adult male albino rats were divided equally into four groups; control, anise extract treated (500 mg/kg orally once daily), diabetic control group (STZ 50 mg/kg once intraperitoneally) and diabetic group treated with anise extract. At the end of experiment (7 weeks), body weight, blood glucose and serum amylase levels were assessed. Pancreatic tissues were subjected to biochemical, histological (light and electron microscopic), and immunohistochemical studies. RESULTS: The diabetic group exhibited significant decrease in body weight and increase in blood glucose and serum amylase levels. Marked degenerative changes affecting both b-cells and acinar cells of the pancreas in the form of a significant decrease in islet's perimeter, vacuolated cytoplasm, pyknotic nuclei, depletion of zymogen granules, dilated congested blood vessels and degenerated organelles were reported. Hyperglycaemia-induced oxidative stress with subsequent upregulation of caspase 3 and beclin 1 immunoreaction were suggested to be implicated in diabetes mellitus pathogenesis. Anise extract ameliorated the all examined parameters via its hypoglycaemic and antioxidant properties with subsequent downregulation of apoptosis and autophagy. CONCLUSIONS: Anise extract can be a promising agent in the control of diabetes mellitus for further clinical trials.


Assuntos
Diabetes Mellitus Experimental , Hiperglicemia , Pimpinella , Animais , Apoptose , Autofagia , Diabetes Mellitus Experimental/induzido quimicamente , Diabetes Mellitus Experimental/tratamento farmacológico , Hiperglicemia/induzido quimicamente , Hiperglicemia/tratamento farmacológico , Hiperglicemia/metabolismo , Estresse Oxidativo , Pâncreas/metabolismo , Extratos Vegetais/farmacologia , Extratos Vegetais/uso terapêutico , Ratos , Estreptozocina/metabolismo
11.
Food Chem Toxicol ; 135: 110875, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31600564

RESUMO

The essential oil of Pimpinella anisum L. (Apiaceae) seeds from Lesvos Island (Greece), famous as flavor for the production of the aperitif "ouzo", has been analyzed by GC-MS for the first time. Additionally, three samples of the Greek market originated from North and Central Greece (Thessaly, Viotia) and Turkey, were also analyzed and all of them were compared to the quality limits given in European Pharmacopoeia for medicinal purposes. The effect of hydrodistillation time found to be very important as the results showed differentiations of the oil yield and the chemical content. The most abundant identified metabolites were trans-anethole, γ-himachalene, estragole and pseudoisoeugenyl 2-methylbutyrate. It is noteworthy, that Lesvos anise oil showed the best quality according to European Pharmacopoeia's standards, while it had the highest yield and the richest chemical composition (28 identified compounds) among all studied samples, contributing to the well known quality of "ouzo" from Plomari. Furthermore, two major secondary metabolites from Lesvos' anise oil: trans-anethole and a mixture of himachalenes have been isolated and structurally determined. Moreover, the safe use of anise oil is discussed due to potential toxic effects of estragole.


Assuntos
Óleos Voláteis/química , Pimpinella/embriologia , Sementes/química , Derivados de Alilbenzenos , Anisóis/análise , Aromatizantes/análise , Cromatografia Gasosa-Espectrometria de Massas , Grécia , Óleos Voláteis/normas
12.
Int J Biol Macromol ; 156: 1530-1538, 2020 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-31785297

RESUMO

The polysaccharide preparation from Pimpinella anisum seeds (PAP) was isolated and characterized to evaluate its laser burn wound-healing and anti-inflammatory activities in mice. The structure characterization of PAP by Infra-red spectrometry (IR), Nuclear magnetic resonance (NMR), Gas chromatogram-Mass spectrometer (GC-MS) and colorimetric methods revealed an optimum yield of 8.84%, a high quantity of carbohydrate (64.75%) and low levels of lipids, protein and sulfate. Galactose (33.47%), ß-d-Glucose (26.71%) and α-d-Mannose (18.21%) were the major monosaccharides components presenting in PAP, and a smaller amounts of ß-d-Galactose, d-Fructose, α-d-Glucose, α-l-Galactose and arabinose were detected. PAP showed noticeable antioxidant and antibacterial properties. The anti-inflammatory activity of PAP in the carrageenan-induced paw edema model in mice, demonstrated by reduced edema and cellular infiltration, and oxidative stress markers in muscle tissue. A beneficial wound healing effect was also revealed. The topical application of PAP based gel on laser burn lesions accelerates wound contraction, the re-epithelization and remodeling phases after seven days of treatment. The results demonstrated that PAP is a novel promising source of natural wound healing and anti-inflammatory drugs. The high content and varied PAP monosaccharides seem to be responsible for the observed biological activities.


Assuntos
Queimaduras/fisiopatologia , Pimpinella/química , Polissacarídeos/química , Polissacarídeos/farmacologia , Sementes/química , Cicatrização/efeitos dos fármacos , Animais , Anti-Inflamatórios/química , Anti-Inflamatórios/farmacologia , Queimaduras/etiologia , Lasers/efeitos adversos , Camundongos , Monossacarídeos/análise
13.
J Econ Entomol ; 113(1): 255-262, 2020 02 08.
Artigo em Inglês | MEDLINE | ID: mdl-31687745

RESUMO

The Colorado potato beetle ranks as one of the most important potato pests, mainly due to its high feeding rate during all developmental stages, particularly third and fourth larval instar, and high fecundity. The effect of essential oil (EO) from anise (Pimpinella anisum L. [Apiales: Apiaceae]) prepared as conventional and encapsulated (EN) formulations on the mortality and antifeedant responses of young larvae of Colorado potato beetles was studied to evaluate the insecticidal and antifeedant effects of five concentrations of this EO and to assess the persistence of both formulations on potato plants. The EN formulation had a significantly higher residual amount compared with that of the conventionally formulated EO. Significantly different values of LC50 and LC90 (ppm) were established for the EO (LC50 = 1,700 and LC90 = 9500) and EN (LC50 = 3,100 and LC90 = 14,300) formulations. The effects of both P. anisum formulations (EO and EN) applied topically to Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae) larvae were distinctly different from those observed with the contact treatment. At the highest concentration of 20,000 ppm, the mortality of the second instars of the L. decemlineata larvae did not exceed 25%. On the other hand, both tested formulations of P. anisum were highly effective when administered orally. The encapsulated EO formulation achieved a distinctly higher biological activity. Our results confirm that the EO from P. anisum, especially the encapsulated formulation, has high insecticidal properties that may lead to the development of new organic products for the control of Colorado potato beetles.


Assuntos
Besouros , Óleos Voláteis , Pimpinella , Solanum tuberosum , Animais , Colorado , Larva
14.
Rev. peru. med. integr ; 5(2): 61-67, 2020. tab
Artigo em Espanhol | LILACS, MOSAICO - Saúde integrativa | ID: biblio-1146106

RESUMO

Objetivos. Determinar los factores asociados al uso de plantas medicinales en gestantes del Hospital Rezola de Cañete en el año 2019. Materiales y métodos. Diseño no experimental, tipo básico, nivel correlacional - transversal, método inductivo; la muestra estuvo conformada por 335 gestantes del Hospital Rezola de Cañete atendidas en el consultorio de ginecoobstetricia y a quienes se le aplicó la encuesta. Resultados. El 88,4% de las gestantes usaron plantas medicinales; el 11,6% no usó plantas medicinales. Entre los factores socioculturales y obstétricos referentes al uso de plantas medicinales se encuentra la edad (p= 12,41); el grado de instrucción (p= 12,35); el número de gestaciones previas (p= 27,63); el lugar de nacimiento (p= 5,09). El factor no asociado fue el lugar de procedencia (p= 3,676). Las plantas más usadas fueron la manzanilla 95%; el anís 65%; el té 58%; la hierba luisa 51%, y la malva 33%. Discusión. La mayoría de las gestantes del Hospital Rezola de Cañete que usaron plantas medicinales manifestaron resultados favorables y no observaron complicación alguna.


Objective. To determine the factors associated with the use of medicinal plants in pregnant women at the Rezola Hospital in Cañete in the year 2019. Materials and methods. Nonexperimental design, basic type, correlational-cross-sectional level, inductive method; the sample was conformed by 335 pregnant women from the Rezola de Cañete Hospital attended in the office of gynecology and obstetrics and to whom the survey was applied. Results. 88.4% of the pregnant women used medicinal plants; 11.6% did not use medicinal plants. Among the sociocultural and obstetric factors related to the use of medicinal plants are age (p= 12.41); education level (p= 12.35); the number of previous pregnancies (p= 27.63); place of birth (p= 5.09). The non-associated factor was the place of origin (p= 3.676). The most used plants were chamomile 95%; aniseed 65%; tea 58%; lemon verbena 51%, and mallow 33%. Discussion. Most of the pregnant women from the Rezola Hospital in Cañete who used medicinal plants showed favorable results and did not observe any complications.


Assuntos
Humanos , Feminino , Gravidez , Adolescente , Adulto , Plantas Medicinais , Gestantes , Peru , Inquéritos e Questionários , Camomila , Pimpinella , Malva , Hospitais Públicos
15.
Biosci. j. (Online) ; 35(6): 1664-1673, nov./dec. 2019. graf, tab
Artigo em Inglês | LILACS | ID: biblio-1049088

RESUMO

The objective of the present study was to assess the influence of the packaging material (cotton cloth bag, multifolium paper and glass container) and storage environment (laboratory and cold chamber conditions) on fennel seedling growth. Seeds were placed in different packaging materials and exposed to the two environments for twelve months. Assessments were made before storage and at every two months and the following were determined: total emergence, emergence speed index, seedling fresh and dry matter. A completely randomized experimental design was used, with four replications in a 2 x 3 x 6+1 factorial design in split split plots, where the plot was the storage environment (laboratory and cold chamber conditions); the split plot was the storage (cotton cloth bag, multifolium paper and glass container) and the split plot was the storage periods (2, 4, 6, 8, 10 and 12 months) and plus an additional treatment (before storage). The results showed that the fennel seedlings had superior growth when their seeds were placed in the glass packaging material, regardless of the storage environment.


O objetivo deste trabalho foi avaliar a influência da embalagem (saco de algodão, papel multifoliado e vidro) e do ambiente de armazenamento (condições de laboratório e câmara fria) no crescimento de plântulas de erva doce. Para isso, as sementes foram acondicionadas nas diferentes embalagens e expostas aos dois ambientes durante doze meses. As avaliações foram feitas antes do armazenamento e a cada dois meses, tendo sido determinado: emergência total, índice de velocidade de emergência, massa fresca e seca das plântulas. Utilizou-se o delineamento experimental inteiramente casualizado, com quatro repetições, num esquema fatorial 2 x 3 x 6 + 1 em parcelas subsubdivididas, no qual a parcela foi o ambiente de armazenamento (condições de laboratório e câmara fria); a subparcela as embalagens (saco de algodão, papel multifoliado e vidro) e a subsubparcela os períodos de armazenamento (2, 4, 6, 8, 10 e 12 meses) e mais um tratamento adicional (antes do armazenamento). Pelos resultados, demonstrou-se que as plântulas de erva doce apresentaram crescimento superior quando suas sementes foram acondicionadas na embalagem de vidro, independente do ambiente de armazenamento.


Assuntos
Embalagem de Produtos , Pimpinella , Foeniculum , Armazenamento de Alimentos , Sementes
16.
J Wound Care ; 28(Sup10): S26-S36, 2019 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-31600102

RESUMO

OBJECTIVE: To assess the wound healing potential of Pimpinella anisum on cutaneous wounds in diabetic rats. METHOD: Full-thickness excisional wounds were made on the back of male, Sprague-Dawley rats with diabetes. The rats were randomly allocated into four treatment groups: 1ml basal cream; tetracycline (3%); Pimpinella anisum 10% for 14 days; and a control group. At days seven, 14 and 21 post-injury, five animals of each group were euthanised, and wounds were assessed through gross, histopathological and oxidant/antioxidant evaluations. Additionally, the dry matter and hydroxyproline contents of the skin samples were measured. RESULTS: A total of 60 rats were used in the study. A significant decrease in the wound size was observed in treated animals with Pimpinella anisum compared with other groups during the experiment. Additionally, treatment with Pimpinella anisum decreased the number of lymphocytes and improved the number of fibroblasts at the earlier stages and increased a number of fibrocytes at the later stages of wound healing. Other parameters such as re-epithelialisation, tissue alignment, greater maturity of collagen fibres and large capillary-sized blood vessels revealed significant changes when compared with the control. Pimpinella anisum significantly reverted oxidative changes of total antioxidant capacity, malondialdehyde and glutathione peroxidase induced by diabetic wounds (p<0.05). Furthermore, it significantly increased the dry matter and hydroxyproline contents at various stages of wound healing (p<0.05). CONCLUSION: The present study showed that application of Pimpinella anisum extract promotes wound healing activity in diabetic rats. The wound-healing property of Pimpinella anisum can be attributed to the phytoconstituents present in the plant.


Assuntos
Diabetes Mellitus Experimental/induzido quimicamente , Diabetes Mellitus Experimental/tratamento farmacológico , Fitoterapia/métodos , Pimpinella/química , Extratos Vegetais/uso terapêutico , Estreptozocina/efeitos adversos , Cicatrização/efeitos dos fármacos , Animais , Humanos , Masculino , Modelos Animais , Ratos , Ratos Sprague-Dawley
17.
J Complement Integr Med ; 17(2)2019 Sep 06.
Artigo em Inglês | MEDLINE | ID: mdl-31490773

RESUMO

Background Depression is a psychiatric disease condition and the chronic mild stress (CMS) model is a well-known and valuable animal model of depression. Geranium oil and anise oil were chosen for such a study. The aim of this research was to establish the geranium oil and anise oil effect to ameliorate CMS-related symptoms. Methods This research included 80 male albino rats each group of 10 rats and the animals were divided into two major groups: normal and CMS. The normal group was subdivided into four (control, geranium oil, anise oil and venlafaxine drug) subgroups treated orally with saline, geranium oil, anise oil and venlafaxine drug, respectively, for 4 weeks. The CMS group was subdivided into four (CMS without any treatment, CMS + geranium oil, CMS + anise oil and CMS + venlafaxine drug) subgroups treated orally with geranium oil, anise oil and venlafaxine drug, respectively, for 4 weeks. Results The sucrose consumption in sucrose preference test, the distance traveled test and center square entries test were decreased, while center square duration test, immobility time in tail suspension test and floating time in forced swimming test were increased in CMS. The superoxide dismutase, glutathione peroxidase, glutathione-S-transferase, glutathione reductase and catalase levels decreased but malondialdehyde and nitric oxide levels increased in brain cerebral cortex and hippocampus areas in CMS. The oral intake of geranium oil and anise oil pushes all these parameters to approach the control levels. These results were supported by histopathological investigations of both brain cerebral cortex and hippocampus tissues. Conclusions Geranium oil and anise oil ameliorate CMS-related symptoms and this effect were related to the antioxidant effects of oils.


Assuntos
Antioxidantes/farmacologia , Depressão/tratamento farmacológico , Suplementos Nutricionais , Óleos Vegetais/farmacologia , Animais , Encéfalo/efeitos dos fármacos , Modelos Animais de Doenças , Geranium/química , Masculino , Pimpinella/química , Ratos , Estresse Psicológico/tratamento farmacológico
18.
Saudi Med J ; 40(4): 391-396, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30957134

RESUMO

OBJECTIVES: To assess the prevalence and pattern of the use of herbal medicines by allergic patients in Western Kingdom of Saudi Arabia. Methods: Cross-sectional study design was used to collect data from consecutively recruited patients with chronic allergic disorders from July 2018 to  October 2018. Participants from 2 allergy clinics in Jeddah, Kingdom of Saudi Arabia were interviewed face-to-face using a structured questionnaire. Results: One hundred and two patients with allergy were interviewed. Their average age was 34±18 and 72.5% were female. The most common primary diagnoses were allergic rhinitis (24.5%), atopic dermatitis (19.6%), and bronchial asthma (16.7%). Herbal medicines were used by 60% of participants, including: Nigella sativa (19.6%), Pimpinella anisum (12.7%), Boswellia sacra (11.8%), Zingiber officinale (10.8%), Foeniculum vulgare (9.8%), Psidium guajava (9.8%), Olea europaea (8.8%), Thymus vulgaris (5.9%), Matricaria chamomilla (4.9%), Mentha piperita (4.9%), Syzygium aromaticum (4.9%), and others. Of those, 63% reported subjective improvement in symptoms. A significant association was found between asthma and herbal medicines intake (p=0.001). Conclusion: Despite the insufficient evidence, there was a high prevalence of herbal medicines used by allergic patients (more than half), especially in bronchial asthma. Black seed, anise and olibanum were the most commonly used.


Assuntos
Asma/tratamento farmacológico , Asma/epidemiologia , Dermatite Atópica/tratamento farmacológico , Dermatite Atópica/epidemiologia , Uso de Medicamentos/estatística & dados numéricos , Fitoterapia/estatística & dados numéricos , Extratos Vegetais/uso terapêutico , Rinite Alérgica/tratamento farmacológico , Rinite Alérgica/epidemiologia , Adolescente , Adulto , Boswellia , Doença Crônica , Estudos Transversais , Feminino , Humanos , Masculino , Nigella sativa , Pimpinella , Prevalência , Arábia Saudita/epidemiologia , Inquéritos e Questionários , Resultado do Tratamento , Adulto Jovem
19.
J Ethnopharmacol ; 236: 155-160, 2019 May 23.
Artigo em Inglês | MEDLINE | ID: mdl-30853645

RESUMO

Seyed Hamdollah Mosavat has made substantial contributions in conception, designing, acquisition of data and preformed clinical trial., Amin Moayedfard and Abbas Rahimi Jaberi had contribution in designing and preformed clinical trial. Zahra Sobhani and Maryam Mosaffa-Jahromi designed and prepared drugs of study. Aida Iraji has made drug biochemical assay. Seyed Hamdollah Mosavat had contribution in designing and revised the manuscript critically for important intellectual content and had contribution in designing and analyzing of data. Seyed Hamdollah Mosavat, Amin Moayedfard and Abbas Rahimi Jaberi had contribution in conception and designing and revised the manuscript critically for important intellectual content. All authors read and approved the final manuscript.


Assuntos
Analgésicos/uso terapêutico , Transtornos de Enxaqueca/tratamento farmacológico , Pimpinella/química , Óleos Vegetais/uso terapêutico , Administração Cutânea , Adulto , Analgésicos/administração & dosagem , Analgésicos/isolamento & purificação , Método Duplo-Cego , Feminino , Humanos , Masculino , Medição da Dor , Projetos Piloto , Óleos Vegetais/administração & dosagem , Óleos Vegetais/isolamento & purificação , Resultado do Tratamento
20.
Food Chem ; 288: 47-56, 2019 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-30902314

RESUMO

The effect of Pimpinella saxifraga essential oil (PSEO) addition (1-3%) in sodium alginate coating on the bacterial and oxidative stability of cheese was studied during refrigerated storage. The GC-HRMS analysis of PSEO showed that anethole, pseudoisoeugenol and p-anisaldehyde were the main components. The PSEO exhibited strong in vitro DPPH radical scavenging activity (IC50 = 6.81 µg/mL), ß-carotene bleaching inhibition (IC50 = 206 µg/mL), ferric reducing power (EC50 = 35.20 µg/mL), total antioxidant activity (213.96 ±â€¯11.12 µmol/mL α-tocopherol equivalent) and notable DNA protection potential. Additionally, PSEO displayed potent antibacterial activity against 3 Gram-positive and 3 Gram-negative bacteria (MICs = 0.78-3.12 mg/mL). The acute toxicity of PSEO was determined using mice model (LD50 = 976.2 mg/kg). The enrichment of sodium alginate coating with PSEO, particularly at 3%, improved cheese preservation by reducing the weight loss, preserving the pH and color and enhancing oxidative and bacterial stability without unpleased flavor for consumers.


Assuntos
Antioxidantes/química , Queijo , Conservação de Alimentos/métodos , Óleos Voláteis/química , Pimpinella/metabolismo , Alginatos/química , Animais , Queijo/microbiologia , Bactérias Gram-Negativas/efeitos dos fármacos , Bactérias Gram-Positivas/efeitos dos fármacos , Concentração de Íons de Hidrogênio , Camundongos , Testes de Sensibilidade Microbiana , Óleos Voláteis/farmacologia , Pimpinella/química
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