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1.
Eur J Psychotraumatol ; 13(1): 2087979, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35790102

RESUMO

Background: Parents of children with intellectual and developmental disorders often experience potentially traumatic events while caring for their children. Heightened posttraumatic stress (PTS) and posttraumatic growth (PTG) have been found in this population. Objective: We aimed to explore risk and protective factors for their PTS and PTG. Method: A cross-sectional study was conducted with 385 parents (average age M = 43.14 years, SD = 7.40; 95.3% mothers). Results: Parenting trauma showed an adverse effect on developing PTS (beta = 0.25, p < .01) and a positive role in promoting PTG (beta = 0.16, p < .01). Social support was protective in its correlation with lower levels of PTS (beta = -0.12, p < .01) and higher levels of PTG (beta = 0.22, p < .01). Barriers to care were associated with increased PTS (beta = 0.23, p < .01), but unrelated to PTG (beta = .01, p = .855). Negative parenting showed a significant, but small, correlation with more severe PTS (beta = 0.11, p < .05), and was unrelated to PTG (beta = -0.09, p = .065). Conclusions: Our study increases the understanding of posttraumatic reactions in parents, predominantly mothers, of children with IDD and identified parenting-related trauma, social support, and barriers to mental health care as predictive factors of the reactions. More research is needed to confirm and validate the effects of the discussed factors. Although causation can not be inferred, prompt and adequate screening and therapeutic resources should be provided to those mothers who were exposed to multiple stressful caregiving events and had limited healthcare access and less support from their spouses, peers, and caregiving partners. HIGHLIGHTS: Parents of a child with Intellectual and Developmental Disorders with parenting trauma had higher posttraumatic stress (PTS) and posttraumatic growth (PTG).Social support was related to lower PTS and higher PTG.Barriers to care were related to higher PTS but unrelated to PTG.


Antecedentes: Los padres de niños con trastornos intelectuales y del desarrollo a menudo experimentan eventos potencialmente traumáticos mientras cuidan a sus hijos. En esta población se han encontrado un elevado estrés postraumático (PTS por sus siglas en ingles) y crecimiento postraumático (PTG por sus siglas en ingles).Objetivo: Nuestro objetivo fue explorar los factores protectores y de riesgo para PTS y PTG.Método: Se realizó un estudio transversal con 385 padres (con edad promedio M = 43,14 años, DS = 7,40; 95,3% madres).Resultados: El trauma parental mostró ser un efecto adverso en el desarrollo de PTS (beta = 0.25, p < 0.01) y un papel positivo en la promover el PTG (beta = 0.16, p < 0,01). El apoyo social fue protector en su correlación con niveles más bajos de PTS (beta = −0.12, p < .01) y niveles más altos de PTG (beta = 0.22, p < .01). Las barreras a la atención se asociaron con un aumento de PTS (beta = 0.23, p < 0.01), pero no se relacionaron con PTG (beta = 0.01, p = 0,855). La crianza negativa mostró una correlación significativa, pero pequeña, con PTS más severos (beta = 0.11, p < 0,05) y no estuvo relacionado con el PTG (beta = −0.09, p = 0.065).Conclusiones: Nuestro estudio aumenta la comprensión de las reacciones postraumáticas en los padres, predominantemente madres, de niños con IDD e identificó el trauma relacionado con la crianza, el apoyo social y las barreras para la atención de la salud mental como factores predictivos de estas reacciones. Se necesita más investigación para confirmar y validar los efectos de los factores discutidos. Si bien no se puede inferir causalidad, se deben proporcionar recursos terapéuticos y de detección, rápidos y adecuados, a aquellas madres que estuvieron expuestas a múltiples eventos estresantes del cuidado y tuvieron acceso limitado a la atención médica y menos apoyo de sus cónyuges, compañeros y cuidadores.


Assuntos
Crescimento Psicológico Pós-Traumático , Transtornos de Estresse Pós-Traumáticos , Adaptação Psicológica , Adulto , Criança , Estudos Transversais , Deficiências do Desenvolvimento , Humanos , Poder Familiar , Pais/psicologia , Fatores de Proteção , Transtornos de Estresse Pós-Traumáticos/diagnóstico
2.
Clin Neuropharmacol ; 45(4): 79-83, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35849689

RESUMO

INTRODUCTION: Little is known about the association between Yerbamate (YMT) tea consumption and Parkinson disease (PD). We determined whether there was an association between YMT tea consumption and PD. METHODS: We conducted a multicenter case-control study in 3 countries (Argentina, Paraguay, and Uruguay). We applied a structured questionnaire about YMT tea consumption history. The survey also included information about factors previously associated with a decreased and increased risk of PD, apart from medical and demographic factors. Odds ratios and 95% confidence intervals were calculated using multivariate unconditional binary logistic regression analysis. RESULTS: We included 215 cases and 219 controls. The mean age of the cases was 65.6 ± 10.5 years and that of controls was 63.1 ± 10.5 years (P < 0.02). Years of YMT tea consumption, number of liters drunk per day, and amount of YMT used for preparing the infusion were similar between cases and controls (P > 0.05), but not the number of times the YMT was added into the container (P = 0.003) and the YMT tea concentration per serving (P = 0.02). The multivariate analysis showed that YMT tea concentration per serving lowered the risk for PD, independent of potential confounders (odds ratio, 0.62; 95% confidence interval, 0.47-0.84). CONCLUSIONS: This multicenter study highlights the association between an environmental factor, the YMT tea drinking, and PD. Although more evidence from longitudinal studies is needed, the results obtained here points toward a protective effect of the YMT tea concentration per serving on PD.


Assuntos
Doença de Parkinson , Chá , Idoso , Estudos de Casos e Controles , Humanos , Pessoa de Meia-Idade , Doença de Parkinson/epidemiologia , Doença de Parkinson/prevenção & controle , Fatores de Proteção , Fatores de Risco , Chá/efeitos adversos
3.
Artigo em Inglês | MEDLINE | ID: mdl-35897497

RESUMO

Background: Understanding and encouraging social and emotional well-being (SEWB) among Indigenous adolescents is vital in countering the impacts of colonisation and intergenerational trauma. As self-harm and suicidality are considered markers of poor SEWB among Indigenous communities, we aimed to identify the individual-level and community-level factors protecting Indigenous adolescents from self-harm and suicidality. Methods: Data came from Footprints in Time-The Longitudinal Study of Indigenous Children (waves 10 and 11), conducted among Indigenous families across Australia. A strengths-based analysis fitted multilevel logistic regression to explore associations with factors proposed as protective against self-reported self-harm and suicidality among Indigenous adolescents. Results: Our study cohort included 365 adolescents with complete data for the variables of interest. Adolescents had a mean (SD) age of 14.04 (0.45) years and a sex ratio of almost 1:1, and most were attending school (96.2%). Previous self-harm was reported by 8.2% (n = 30); previous suicidality was reported by 4.1% (n = 15). Individual-level factors protecting against self-harm and suicidality were being male, living in a cohesive family, and having low total Strengths and Difficulty Questionnaire scores (p < 0.05 for all). Residing in major cities compared with regional/remote areas was protective against self-harm (OR 5.94, 95% CI 1.31-26.81). Strong cultural identity was not found to be a protective factor against self-harm and/or suicidality in the sample. Conclusions: This study identified key individual- and community-level factors that can protect Australian Indigenous adolescents against self-harm and suicidality, particularly family cohesion. Identifying strengths for this at-risk population can inform prevention strategies, particularly for rural living adolescents with high distress.


Assuntos
Comportamento Autodestrutivo , Suicídio , Adolescente , Austrália/epidemiologia , Criança , Feminino , Humanos , Estudos Longitudinais , Masculino , Fatores de Proteção , Comportamento Autodestrutivo/epidemiologia , Comportamento Autodestrutivo/psicologia , Ideação Suicida
4.
PLoS One ; 17(7): e0271809, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35862416

RESUMO

BACKGROUND: The insulin-like growth factor 1 (IGF1) gene is located within the myopia-associated MYP3 interval, which suggests it may play an important role in the progression of myopia. However, the association between IGF1 SNPs and any myopia is rarely reported. METHODS: A comprehensive literature search was conducted on studies published up to July 22, 2021 in PubMed, EMBASE, CBM, COCHRANE, CNKI, WANFANG and VIP databases. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated for single-nucleotide polymorphisms (SNPs) that have been evaluated in at least three studies. RESULTS: Nine studies involving 4596 subjects with any myopia and 4950 controls examined 25 SNPs in IGF1 gene, among which seven SNPs were included in this meta-analysis. Significant associations were not found in any genetic models between rs6214, rs12423791, rs5742632, rs10860862, rs5742629 and any myopia. Rs2162679 was suggestively associated with any myopia in the codominant model (GA vs. AA: OR = 0.87, 95% CI: 0.76-1.00) and the dominant model (GG+GA vs. AA: OR = 0.88, 95% CI = 0.78-1.00). CONCLUSION: Meta-analysis of updated data reveals that the G allele of the IGF1 rs2162679 SNP is a potential protective factor for any myopia, which is worth further researches.


Assuntos
Fator de Crescimento Insulin-Like I , Miopia , Polimorfismo de Nucleotídeo Único , Alelos , Estudos de Casos e Controles , Predisposição Genética para Doença , Humanos , Fator de Crescimento Insulin-Like I/genética , Miopia/genética , Fatores de Proteção
5.
Crim Behav Ment Health ; 32(2): 67-74, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35778848

RESUMO

Much research has sought to distinguish key interacting factors affecting children as they develop which influence later outcomes. Some factors, notably adverse childhood experiences (ACEs), pose serious risks for later health or mental health problems for the children or predispose them for involvement in offending behaviours. However, other experiences, alongside ACEs, also pose risks and yet others offer protection. A matrix showing interacting influences from the mother's pregnancy onwards was published earlier; a revised matrix has been developed, showing a fresh picture of cumulative risk and protective factors.


Assuntos
Experiências Adversas da Infância , Criança , Família , Feminino , Humanos , Gravidez , Fatores de Proteção
6.
Artigo em Inglês | MEDLINE | ID: mdl-35886458

RESUMO

A majority of the workforce in the humanitarian aid consists of volunteers who partly suffer from health problems related to their voluntary service. To date, only a fraction of the current research focuses on this population. The aim of this qualitative explorative study was to identify burdening and protective organisational factors for health and well-being among humanitarian aid volunteers in a Greek refugee camp. To this end, interviews with 22 volunteers were held on site and afterwards analysed by using qualitative content analysis. We focused on international volunteers working in Greece that worked in the provision of food, material goods, emotional support and recreational opportunities. We identified burdening factors, as well as protective factors, in the areas of work procedures, team interactions, organisational support and living arrangements. Gender-specific disadvantages contribute to burdening factors, while joyful experiences are only addressed as protective factors. Additionally, gender-specific aspects in the experience of team interactions and support systems were identified. According to our findings, several possibilities for organisations to protect health and well-being of their volunteers exist. Organisations could adapt organisational structures to the needs of their volunteers and consider gender-specific factors.


Assuntos
Campos de Refugiados , Refugiados , Grécia , Humanos , Organizações , Fatores de Proteção , Pesquisa Qualitativa , Voluntários
7.
Psychoneuroendocrinology ; 143: 105819, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35724562

RESUMO

Intrusions, a key symptom of posttraumatic stress disorder (PTSD), can occur in the form of images but also as pain sensations. Similar to audiovisual intrusions, the frequency and persistence of pain intrusions varies greatly between individuals. In the current study, we examined whether peritraumatic circulating 17ß-estradiol (E2) levels are a biologic factor associated with subsequent audiovisual (i.e., film) and pain intrusion development, and whether peritraumatic stress levels modulate this relationship. Forty-one free-cycling women participated in an ecologically informed trauma-pain-conditioning (TPC) paradigm, using trauma-films and pain as unconditioned stimuli. Independent variables were salivary peritraumatic E2 levels and stress indexed by salivary cortisol and self-reported state-anxiety during TPC. Outcomes were film- and pain-intrusions occurring during daily-life in the week following TPC and a Memory-Triggering-Task in response to conditioned stimuli 24 h after TPC. In the week after analogue-trauma, higher peritraumatic E2 levels were associated with a greater probability of experiencing film-intrusions in the beginning of the week, which switched to a lower probability toward the end of the week. This time-dependent relationship between E2 and film-intrusions only held for higher state-anxious women. In contrast, results indicated a consistent inverse relationship between peritraumatic E2 levels and pain-intrusions during daily-life and Memory-Triggering-Task. Together, these data suggest that higher peritraumatic E2 levels could be associated with lower long-term visual trauma intrusions, as well as lower pain-intrusions, and thereby possibly constitute a protective biologic factor for PTSD and potentially also for chronic pain.


Assuntos
Estradiol , Transtornos de Estresse Pós-Traumáticos , Fatores Biológicos , Condicionamento Clássico/fisiologia , Feminino , Humanos , Dor , Fatores de Proteção
8.
Artigo em Inglês | MEDLINE | ID: mdl-35742361

RESUMO

In France, nurses work either in hospitals and care institutions or in private practice, following physicians' prescriptions and taking care of patients at their homes. During the COVID-19 pandemic, these populations of nurses were exposed to numerous sources of stress. The main objective of the present study was to identify the protective factors they mobilized to face the crisis and how these factors contributed to sustaining their quality of life (QoL). A cross-sectional study was conducted to answer these questions. Overall, 9898 French nurses participated in the study, providing demographic information and filling out QoL (WHOQOL-BREF), perceived stress (PSS-14), resilience (CD-RISC), social support (MSPSS), and coping style (BRIEF-COPE) questionnaires. The results revealed very few differences between the two groups of nurses, which is surprising given the drastically different contexts in which they practice. Social support and two coping strategies (positive reframing and acceptance) were associated with a high QoL, whereas perceived stress and four coping strategies (denial, blaming self, substance use, and behavioral disengagement) were associated with poor QoL. In the light of these results, we recommended promoting social support and coping strategies to help nurses cope during the pandemic.


Assuntos
COVID-19 , Qualidade de Vida , Adaptação Psicológica , COVID-19/epidemiologia , Estudos Transversais , Hospitais , Humanos , Pandemias , Prática Privada , Fatores de Proteção , Inquéritos e Questionários
9.
Schizophr Res ; 244: 111-117, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35661996

RESUMO

OBJECTIVE: This study aim to explore the prevalence of current PLEs over past month and relevant influential factors among adolescents. METHODS: A total of 67,538 students completed one online survey between April 21st and May 12th, 2021. Current PLEs were assessed using the 8-item Positive Subscale of the Community Assessment of Psychic Experiences (CAPE-P8). Participants were defined as having frequent PLEs if they selected "often" or "nearly always" on one or more items of CAPE-P8. Family function, school climate and a series of socio-demographic were also evaluated. RESULTS: In this sample, 49.3% adolescents reported having at least one PLE over the past month, while 15.4% experienced high frequent PLEs. Alcohol intake was positively associated with high frequent PLEs (OR = 2.61, 95% CI = 2.37-2.88). Adolescents with chronic physical illness (OR = 1.94, 95% CI = 1.73-2.18) or family history of psychiatric illness (OR = 2.61, 95% CI = 2.22-2.77) were more likely to suffer from high frequent PLEs. Dysfunction family function (OR moderate = 1.98, 95% CI = 1.98-2.09; OR severe = 6.98, 95% CI = 6.48-7.53) or poor school climate (OR = 3.14, 95% CI = 2.93-3.37) was associated with elevated high frequent PLEs. CONCLUSIONS: Several factors of socio-demographics, unhealthy lifestyle, family and school environments are found to be related to frequent PLEs. These factors should also be taken into consideration for effective psychosocial intervention in adolescents.


Assuntos
Transtornos Mentais , Transtornos Psicóticos , Adolescente , China/epidemiologia , Estudos Transversais , Humanos , Transtornos Mentais/epidemiologia , Fatores de Proteção , Transtornos Psicóticos/epidemiologia , Transtornos Psicóticos/psicologia , Fatores de Risco , Inquéritos e Questionários
10.
Maturitas ; 161: 55-57, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35688496

RESUMO

We examined relationships between combinations of protective factors (healthy weight, never smoking, and at least moderate levels of physical activity) and moderate or substantial limitations of physical function (PF) versus minimal PF limitations in women who had had a hysterectomy only (n = 1771) or a hysterectomy and bilateral oophorectomy (BO) (n = 738) participating in the Australian Longitudinal Study on Women's Health. We found a dose-response effect that was strongest for substantial PF limitations; for each additional healthy behaviour, for women who had undergone hysterectomy only the relative risk (RR) was 0.62 (95% confidence interval (CI) 0.56-0.69) and for women who had undergone hysterectomy-BO the RR was 0.70 (95% CI 0.60-0.82). Support to adopt these modifiable factors may improve physical function in women who have had a hysterectomy.


Assuntos
Histerectomia , Austrália , Estudos de Coortes , Feminino , Humanos , Estudos Longitudinais , Ovariectomia , Estudos Prospectivos , Fatores de Proteção , Fatores de Risco
11.
Rev. SPAGESP ; 23(1): 159-174, jan.-jun. 2022.
Artigo em Português | LILACS, Index Psicologia - Periódicos | ID: biblio-1356777

RESUMO

RESUMO O objetivo deste estudo foi analisar a literatura científica no período de janeiro de 2006 a março de 2021 sobre as repercussões da perda gestacional na conjugalidade e na parentalidade. Trata-se de uma revisão sistemática que envolveu consulta às bases Pubmed, PsycNET e Portal BVS, por meio de descritores estabelecidos previamente, resultando em 16 estudos elegíveis para análise. Foram encontrados resultados contrastantes quanto às repercussões da perda gestacional na parentalidade, sugerindo a necessidade de investigação de fatores de proteção. A perda apresentou-se como risco à conjugalidade, porém a comunicação conjugal emergiu como fator de proteção que merece maior investigação. Estudos futuros devem adotar métodos qualitativos ou mistos, incluir a perspectiva masculina sobre o tema e avaliar intervenções conjugais e familiares.


ABSTRACT This study aimed to analyze the scientific production from Jan 2006 to Mar 2021 regarding the repercussions of pregnancy loss on conjugality and parenthood. It is a systematic review carried out in Pubmed, PsycNET, and Portal BVS database through previously established descriptors, resulting in 16 eligible studies. We found contrasting results regarding repercussions in parenthood, suggesting the need to investigate protective factors also. Pregnancy loss shows as a risk for marital relationships, but marital communication emerged as a possible protection factor that deserves further investigation. Future research should adopt qualitative and mixed methods, include men’s perspectives, and evaluate marital and family interventions.


RESUMEN El objetivo de este estudio ha sido analizar la literatura científica en el período de enero de 2006 hasta marco de 2021 sobre las repercusiones de la pérdida gestacional en la conyugalidad y en la parentalidad. Esta es una revisión sistemática realizada en las bases Pubmed, PsycNET y Portal BVS, con los descriptores establecidos previamente, resultando en 16 estudios elegibles. Se encontraron resultados contrastantes en cuanto a las repercusiones en la crianza de los hijos, sugiriendo la necesidad de investigar también los factores protectores. La pérdida se presentó como un riesgo para la conyugalidad, sin embargo, la comunicación marital emergió como un posible factor protector que merece más estudios. Se indica que futuras investigaciones adopten métodos cualitativos, que incluyan la perspectiva masculina y evalúen intervenciones conyugales y familiares.


Assuntos
Relações Pais-Filho , Casamento , Aborto Espontâneo , Poder Familiar , Fatores de Proteção
12.
J Clin Lab Anal ; 36(7): e24548, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35692085

RESUMO

OBJECTIVES: This study aimed to investigate the effect of hemoglobin (Hb) fluctuation after dialysis on the prognosis of cardiovascular-related and all-cause deaths in peritoneal dialysis (PD). METHODS: According to the Hb fluctuation, patients were divided into low fluctuation group, moderate fluctuation group, and high fluctuation group, and then, the effects of Hb fluctuation after dialysis on the prognosis of cardiovascular-related and all-cause death in PD were analyzed by regression analysis. RESULTS: A total of 232 patients were selected in this study. Compared with the low Hb fluctuation group, the moderate and high fluctuation groups had lower body mass index (BMI), estimated glomerular filtration rate (eGFR), and baseline Hb, and the moderate fluctuation group had less erythropoietin (EPO) and dialysis dose. Compared with survivors, patients with cardiovascular-related and all-cause deaths had lower mean Hb and Hb fluctuation (all p < 0.05). Cox regression analysis showed that before and after adjusting for confounding factors, Hb fluctuation was still independently correlated with cardiovascular prognosis, and higher Hb fluctuation was still a protective factor for cardiovascular-related death in the Hb-substandard group, but there was no significant correlation between Hb fluctuation and all-cause death. Multivariate linear regression analysis revealed that Hb fluctuation was positively correlated with Kt/V and EPO dosage, but negatively correlated with the baseline Hb. CONCLUSION: High Hb fluctuation was a protective factor for cardiovascular-related death in PD with substandard Hb. Compared with Hb fluctuation, correction of anemia timely and making Hb reaches the standard level had a greater impact on reducing cardiovascular-related death in PD.


Assuntos
Falência Renal Crônica , Diálise Peritoneal , Hemoglobinas/análise , Humanos , Diálise Peritoneal/efeitos adversos , Fatores de Proteção , Diálise Renal , Estudos Retrospectivos
13.
PLoS One ; 17(6): e0268742, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35709145

RESUMO

Hispanic/Latino men who have sex with men (MSM) have the second largest HIV infection rate in the United States and Puerto Rico (PR) has ranked number five with the greatest number of Hispanics living with HIV. This study aims to understand how family affects HIV risk and protective factors for young adults. PR MSM ages 21 through 30 in San Juan, PR completed semi-structured interviews exploring the influence interpersonal family relationships have on HIV risk and protective factors. PR MSM (N = 15) completed a semi-structured in-depth individual interview. NVivo was used for administering a thematic analysis based on the transcripts in the original language of the interview, 14 in Spanish and one in English. The following five general themes emerged from the data analysis: 1) Immediate versus Extended Family; 2) The Matriarch; 3) Fractured Paternal Relationships; 4) Siblings Influence; and 5) Fictive Kin-Creating My Own Family. Findings suggest that the immediate family play an integral role in enhancing HIV protective factors for PR MSM as young adults. This study highlights the importance for developing family-based interventions that reinforce cultural beliefs and values through a strengths-based approach towards enhancing HIV protective behaviors for PR MSM.


Assuntos
Infecções por HIV , Minorias Sexuais e de Gênero , Adulto , Infecções por HIV/epidemiologia , Infecções por HIV/prevenção & controle , Hispânico ou Latino , Homossexualidade Masculina , Humanos , Masculino , Fatores de Proteção , Porto Rico/epidemiologia , Estados Unidos/epidemiologia , Adulto Jovem
14.
Front Immunol ; 13: 889954, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35663979

RESUMO

The role of the unfolded protein response (UPR) in plasma cells (PC) and their malignant multiple myeloma (MM) counterparts is a well described area of research. The importance of autophagy in these cells, as well as the interplay between autophagy and the UPR system, has also been well studied. In this review, we will discuss the relationship between these two cellular responses and how they can be utilized in MM to account for the high levels of monoclonal immunoglobulin (Ig) protein synthesis that is characteristic of this disease. Interactions between MM cells and the bone marrow (BM) microenvironment and how MM cells utilize the UPR/autophagy pathway for their survival. These interacting pathways form the foundation for the mechanism of action for bortezomib, a proteasome inhibitor used to modify the progression of MM, and the eventual drug resistance that MM cells develop. One important resistance pathway implicated in MM progression is caspase 10 which attenuates autophagy to maintain its prosurvival function and avoid cell death. We lay a groundwork for future research including 3D in vitro models for better disease monitoring and personalized treatment. We also highlight pathways involved in MM cell survival and drug resistance that could be used as new targets for effective treatment.


Assuntos
Mieloma Múltiplo , Autofagia , Medula Óssea/metabolismo , Bortezomib/farmacologia , Bortezomib/uso terapêutico , Humanos , Mieloma Múltiplo/patologia , Fatores de Proteção , Microambiente Tumoral
15.
Artigo em Inglês | MEDLINE | ID: mdl-35682363

RESUMO

This study looks into the relationship between mental health and social exclusion scenarios, paying special attention to employment-related factors. Previous studies have shown the relationship between mental health, social exclusion and poverty. For this study, authors have used data from the VIII Report on social development and exclusion in Spain, with a sample of 11,655 households. The SPSS Statistics programme was used for statistical analysis. Several factors that could pose a risk or be a protection for the presence of mental health conditions were designed. By means of a binary logistic regression the impact of these factors on mental health issues was scored. The results show that a deteriorated social network and a negative interpretation of reality are the most influential factors related to the presence of mental health conditions in a given household. On the contrary, positive social relationships protect households and function as a support when mental health conditions are already present. Thus, the support of positive and committed social relationships is a key element to protect the mental health of households.


Assuntos
Emprego , Saúde Mental , Estudos Transversais , Emprego/psicologia , Relações Interpessoais , Fatores de Proteção
16.
Artigo em Inglês | MEDLINE | ID: mdl-35682523

RESUMO

Fathers of refugee background with young children can experience significant mental health difficulties, with the potential for intergenerational impacts. This study aimed to explore how fathers of refugee background experience risk and protective factors for their own health and wellbeing during the early years of parenting. Semi-structured interviews and one semi-structured focus group were conducted with fathers of refugee background, with young children (0-5 years), who had settled in Australia. Transcribed interviews were analysed using thematic analysis, informed by the socioecological model of health. A total of 21 fathers participated in the study. Risk factors experienced included: prior experiences of trauma, reduced access to family support in Australia, adjustments in parenting roles, and the challenges of learning a new language and securing employment. Fathers drew on a number of sources of strength, including a sense of joy from fatherhood and support from partners, families, and communities. While most fathers regularly accompanied their partners and children to healthcare appointments, they were rarely asked by healthcare professionals about their own needs. Our findings support the idea that there is a need for greater assistance for fathers, particularly for navigating issues arising from the settlement process. Healthcare services working with families of refugee background must adopt a father-inclusive, trauma-informed approach that is responsive to fathers' needs.


Assuntos
Refugiados , Criança , Pré-Escolar , Humanos , Saúde Mental , Poder Familiar/psicologia , Fatores de Proteção , Pesquisa Qualitativa , Refugiados/psicologia
17.
Iran J Immunol ; 19(2): 4, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35767889

RESUMO

BACKGROUND: Pulmonary fibrosis is common in primary Sjögren's syndrome (pSS)-related interstitial lung disease (ILD). However, research is lacking on the diagnostic immunological examination of pSS-related pulmonary fibrosis. Particularly, the value of detecting anti-Ro52 antibody in pulmonary fibrosis is unclear. OBJECTIVE: To evaluate the potential diagnostic value of anti-SSA, anti-SSB, and anti-Ro52 autoantibodies as markers of pSS-related pulmonary fibrosis. METHODS: One-hundred seventy-nine patients with pSS were analyzed retrospectively at our hospital. They were divided into the fibrosis and non-fibrosis groups. Pulmonary fibrosis was classified as mild, moderate, or severe based on the patients' computed tomography (CT) findings. Laboratory examinations, including anti-SSA, anti-SSB, and anti-Ro52 antibody evaluations, were performed. The influencing factors of pulmonary fibrosis were analyzed using logistic regression. RESULTS: Chest CT revealed pulmonary fibrosis in 45 patients with pSS (25.1%). The positive rates of anti-SSA and anti-Ro52 antibodies in the fibrosis group were lower than in the non-fibrosis group (P=0.04, P=0.001). The frequency of anti-Ro52 antibody showed no significant differences between mild-to-moderate (53.8%) and severe (47.3%) pulmonary fibrosis. The anti-Ro52 antibody was identified as a potentially protective factor against pSS (P=0.041). CONCLUSIONS: Patients with pSS and pulmonary fibrosis had a low frequency of anti-SSA and anti-Ro52 antibodies. In patients with pSS and negative anti-Ro52 antibody, a chest CT is recommended to further understand the patients' condition.


Assuntos
Fibrose Pulmonar , Síndrome de Sjogren , Autoanticorpos , Humanos , Fatores de Proteção , Fibrose Pulmonar/diagnóstico , Estudos Retrospectivos , Ribonucleoproteínas , Síndrome de Sjogren/complicações , Síndrome de Sjogren/diagnóstico
18.
J. Health NPEPS ; 7(1): 1-21, Jan-Jun, 2022.
Artigo em Espanhol | LILACS, BDENF - Enfermagem, Coleciona SUS | ID: biblio-1379768

RESUMO

Objetivo:determinar la relación y el efecto de la edad, la escolaridad, la resiliencia, la satisfacción con la vida y las fortalezas humanas con el consumo de alcohol en universitarios. Método:diseño descriptivo, correlacional y predictivo, los participantes fueron 367 estudiantes (63.2% mujeres) de 18 a 35 años (M=21.64, DE= 2.82) de una universidad del estado de Tabasco, México. Se seleccionaron mediante un muestreo probabilístico aleatorio estratificado. La recolección de datos se realizó durante junio y julio de 2021. Resultados:Los estudiantes con mejores niveles de resiliencia están más satisfechos con la vida y tienen más fortalezas humanas. La edad se relacionó con el consumo de alcohol, y con nivel de bajo riesgo y consumo dependiente. Cuanto menor los índices de fortalezas humanas mayor es el consumo de alcohol de bajo riesgo y consumo de tipo dependiente. Las fortalezas humanas se mostraron como factores predictores (B=-0.14, p<.01) del consumo de alcohol en jóvenes universitarios. Conclusión:Las fortalezas humanas son un predictor negativo del consumo de alcohol en los jóvenes universitarios. Estos hallazgos pueden contribuir para una mejor comprensión del fenómeno del consumo de alcohol.


Objective:to determine the relationship and the effects of age, schooling, resilience, life satisfaction and human strengths with alcohol consumption in university students. Method:descriptive, correlational and predictive design, the participants were 367 students (63.2% women) aged 18 to 35 years (M=21.64, SD= 2.82) from a university in the state of Tabasco, Mexico. They were selected by stratified random probability sampling.Data collection was carried out during June and July 2021. Results:students with higher levels of resilience are more satisfied with life and have more human strengths. Age was related toalcohol consumption, and to low-risk and dependent drinking. The lower the indices of human strengths, the higher the low-risk and dependent alcohol consumption. Human strengths were shown to be predictors (B=-0.14, p<.01) of alcohol consumption in young university students. Conclusion:human strengths are a negative predictor of alcohol consumption in college youth. These findings may contribute to a better understanding of the phenomenon of alcohol consumption.


Objetivo:determinar a relação e o efeito da idade, escolaridade, resiliência, satisfação de vida e forças humanas com o consumo de álcool em estudantes universitários. Método:desenho descritivo, correlativo e preditivo, os participantes eram 367 estudantes (63,2% mulheres) com idades compreendidas entre os 18-35 anos (M=21,64, DP= 2,82) de uma universidade no estado de Tabasco, México. Foram selecionados por amostragem de probabilidade aleatória estratificada. A recolha de dados foi realizada durante os meses de junho e julho de 2021. Resultados:os estudantes com níveis mais elevados de resiliência estão mais satisfeitos com a vida e têm mais forças humanas. A idade estava relacionada com o consumo de álcool, e com o consumo de baixo risco e dependente. Quanto mais baixo o índice de forças humanas, mais alto o baixo risco e o consumo dependente de álcool. As forças humanas foram apontadas como fatores preditivos (B=-0,14, p<.01) do consumo de álcool em jovens estudantes universitários. Conclusão:as forças humanas são um preditor negativo do consumo de álcool na juventude universitária. Estas descobertas podem contribuir para uma melhor compreensão do fenómeno do consumo de álcool.


Assuntos
Estudantes , Consumo de Bebidas Alcoólicas , Fatores de Proteção
19.
Front Immunol ; 13: 872542, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35592323

RESUMO

Background: Common vaccinations may have impacts on dementia risk, but current evidence is inconsistent. We therefore investigated the association between vaccinations and dementia risk by systematic review and meta-analysis approach. Methods: We conducted an extensive search of PubMed, Embase, Cochrane Library, and Web of Science to identify studies that compared the risk of dementia in vaccinated versus unvaccinated populations. The adjusted hazard ratio (HR) and corresponding 95% confidence intervals (CIs) were pooled as measures. Results: Of the 9124 records initially retrieved, 17 studies with 1857134 participants were included in our analysis. The overall pooled results showed that vaccinations were associated with a 35% lower dementia risk (HR=0.65, 95% CI: 0.60-0.71, P overall effect < 0.001; I2 = 91.8%, P heterogeneity<0.001). All types of vaccination were associated with a trend toward reduced dementia risk, with rabies (HR=0.43), tetanus & diphtheria & pertussis (Tdap) (HR=0.69), herpes zoster (HR=0.69), influenza (HR=0.74), hepatitis A (HR=0.78), typhoid (HR=0.80), and hepatitis B (HR=0.82) vaccinations being significant. Individuals with more full vaccination types and more annual influenza vaccinations were less likely to develop dementia. Gender and age had no effect on this association. Conclusion: Routine adult vaccinations are associated with a significant reduction in dementia risk and may be an effective strategy for dementia prevention. Further research is needed to elucidate the causal effects of this association and the underlying mechanisms.


Assuntos
Demência , Difteria , Influenza Humana , Adulto , Demência/epidemiologia , Demência/prevenção & controle , Difteria/prevenção & controle , Humanos , Influenza Humana/prevenção & controle , Fatores de Proteção , Vacinação/métodos
20.
Euro Surveill ; 27(20)2022 05.
Artigo em Inglês | MEDLINE | ID: mdl-35593164

RESUMO

We explored the risk factors associated with SARS-CoV-2 reinfections in Italy between August 2021 and March 2022. Regardless of the prevalent virus variant, being unvaccinated was the most relevant risk factor for reinfection. The risk of reinfection increased almost 18-fold following emergence of the Omicron variant compared with Delta. A severe first SARS-CoV-2 infection and age over 60 years were significant risk factors for severe reinfection.


Assuntos
COVID-19 , SARS-CoV-2 , Humanos , Itália/epidemiologia , Pessoa de Meia-Idade , Fatores de Proteção , Reinfecção
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