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2.
Behav Res Ther ; 154: 104104, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35609375

RESUMO

The brain and immune system are intricately connected, and perturbations in one system have direct effects on the other. This review focuses on these dynamic psychoneuroimmune interactions and their implications for mental and physical health in the context of the COVID-19 pandemic. In particular, we describe how psychological states influence antiviral immunity and the vaccine response, and how immune changes triggered by COVID (either via infection with SARS-CoV-2 or associated stressors) can influence the brain with effects on cognition, emotion, and behavior. We consider negative psychological states, which have been the primary focus of psychological research in the context of COVID-19 (and psychoneuroimmunology more generally). We also consider positive psychological states, including positive affect and eudaimonic well-being, given increasing evidence for their importance as modulators of immunity. We finish with a discussion of interventions that may be effective in improving immune function, the neuro-immune axis, and ultimately, mental and physical health.


Assuntos
COVID-19 , Psiconeuroimunologia , Humanos , Neuroimunomodulação , Pandemias , SARS-CoV-2
5.
Brain Behav Immun ; 102: 206-208, 2022 05.
Artigo em Inglês | MEDLINE | ID: mdl-35240297

RESUMO

Just weeks away from the Opening Ceremony of the Beijing 2022 Winter Olympics, the United States, followed by Australia, the United Kingdom, and Canada, has declared a diplomatic boycott of the Games. A diplomatic boycott stipulates that while government officials of these countries will not attend the event, the athletes' scheduled attendance will largely remain intact. An unintended consequence of the boycotts is that they force the attending athletes to cope with the stress and distress associated with the 2022 Winter Olympics in an unfamiliar environment on their own. It is important to underscore that many of the challenges the athletes could face amid the Games are either deep-rooted or unprecedented, ranging from stressors fuelled by the nonstop media reports, the competitions, to the Omicron scares. These insights combined, in turn, underscore the imperative for effective and preemptive mental health support for Olympic athletes. To shed light on the issue, this paper highlights the reasons why timely solutions are needed to adequately safeguard Olympic athletes' mental health and overall wellbeing, and underlines promising technology-based solutions that can be cost-effectively designed and developed for the athletes.


Assuntos
Psiconeuroimunologia , Esportes , Atletas , Humanos , Estações do Ano , Reino Unido
7.
Perspect Biol Med ; 65(1): 1-24, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35307698

RESUMO

Since psychoneuroimmunology's (PNI) inception four decades ago, so-called "mind-body" approaches relying on or inspired by PNI have offered the promise of healing various ailments based on the age-old but metaphysically ambiguous principle that the mind can heal the body. How this principle is operationalized not only reveals limitations of PNI-based mind-body therapies but offers a test kit of possibilities for exploring the conceptual foundations of PNI. This article presents an integrative analysis of the role of consciousness-related phenomena (such as willful intentions, thoughts, beliefs) in their causal efficacy, examining their relationships with placebo effects and the boundaries of immune homeostatic control, as well as their therapeutic prospects. Focusing on mindfulness, the article notes how understanding the mechanisms of mindfulness, specifically those mechanisms related to consciousness and placebo effects, can lend insight into how it can validly be evaluated for effectiveness. While taking care not to overstate the role of consciousness in the control of immune homeostatic functions, this article places consciousness center stage to evaluate how mindfulness might be harnessed to modulate the immune system in a clinically relevant manner.


Assuntos
Atenção Plena , Psiconeuroimunologia , Estado de Consciência , Humanos , Efeito Placebo
10.
Artigo em Inglês | MEDLINE | ID: mdl-34682637

RESUMO

Adult cancer survivors have an increased prevalence of mental health comorbidities and other adverse late-effects interdependent with mental illness outcomes compared with the general population. Coronavirus Disease 2019 (COVID-19) heralds an era of renewed call for actions to identify sustainable modalities to facilitate the constructs of cancer survivorship care and health care delivery through physiological supportive domestic spaces. Building on the concept of therapeutic architecture, psychoneuroimmunology (PNI) indicators-with the central role in low-grade systemic inflammation-are associated with major psychiatric disorders and late effects of post-cancer treatment. Immune disturbances might mediate the effects of environmental determinants on behaviour and mental disorders. Whilst attention is paid to the non-objective measurements for examining the home environmental domains and mental health outcomes, little is gathered about the multidimensional effects on physiological responses. This exploratory review presents a first analysis of how addressing the PNI outcomes serves as a catalyst for therapeutic housing research. We argue the crucial component of housing in supporting the sustainable primary care and public health-based cancer survivorship care model, particularly in the psychopathology context. Ultimately, we illustrate a series of interventions aiming at how housing environmental attributes can trigger PNI profile changes and discuss the potential implications in the non-pharmacological treatment of cancer survivors and patients with mental morbidities.


Assuntos
COVID-19 , Sobreviventes de Câncer , Neoplasias , Adulto , Habitação , Humanos , Saúde Mental , Morbidade , Neoplasias/epidemiologia , Psiconeuroimunologia , SARS-CoV-2
11.
Rev Esc Enferm USP ; 55: e20210159, 2021.
Artigo em Inglês, Português | MEDLINE | ID: mdl-34516609

RESUMO

OBJECTIVE: To discuss the evolution of research in cancer psychoneuroimmunology, the advances in the management of neuropsychological symptom clusters and their interface with mid-range theories, and practical applications in Nursing. METHOD: This is a theoretical-reflective study anchored in recent literature, as well as in the critical analysis of the authors. RESULTS: This is a promising field of investigation, which emphasizes the complexity and interaction of symptoms, the interrelationships among them, the factors influencing them, and their consequences. Subsidized by mid-range theories in Nursing, such as the Theory of Unpleasant Symptoms and the Theory of Symptom Management, analyses of these interrelationships support Oncology Nursing diagnoses and interventions. CONCLUSION: An innovative approach is proposed to qualify Oncology Nursing care based on the integration of recent advances in cancer psychoneuroimmunology, Nursing mid-range theories, and practical tools such as health coaching. The approach proposed may strengthen clinical nursing practice in the management of neuropsychological symptom clusters in oncology and shall be integrated into decision-making during cancer treatment, favoring person-centered care.


Assuntos
Neoplasias , Enfermagem Oncológica , Humanos , Modelos Teóricos , Cuidados Paliativos , Psiconeuroimunologia
12.
J Urban Health ; 98(Suppl 2): 115-122, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34152521

RESUMO

Improved understanding of perinatal psychoneuroimmunology is needed, particularly to combat the high rates of maternal and infant mortality witnessed among Black Americans. We compared the success of recruitment by advertisement, in person, or by phone during the course of a prospective cohort study of perinatal psychoneuroimmunology among Black American women. Over 24 months, 363 women were assessed and 96 were enrolled. Women recruited by phone were less likely to complete full screening than women recruited by advertisement (OR = 0.32, p < 0.01) or in person (OR = 0.19, p < 0.01). Women recruited by advertisement were less likely to complete full screening than women recruited in person (OR = 0.60, p = 0.05). Odds of unsuccessful contact were 13.2 and 11.5 times greater among women recruited by phone versus by advertisement or in person, respectively (p values ≤ 0.01). Women recruited by advertisement and in person showed similar odds of unsuccessful contact (OR = 0.87, p = 0.76). Odds of screening decline were similar following recruitment in person or by phone when contact was successful (OR = 0.85, p = 0.76). Focusing on eligible women (n = 142), those recruited in person were significantly less likely to enroll than those recruited by advertisement (OR = 0.28, p < 0.01; Fig. 4). Considering all women (n = 363), odds of enrollment did not significantly differ among the recruitment groups (p values ≥ 0.09). Most (93.8%) enrolled women consented to biological specimen banking. Findings from this brief report provide a starting point for perinatal scientists to critically consider not only how to maximize research efforts but also how research team actions may perpetuate or assuage the research mistrust introduced by long-standing social inequities.


Assuntos
Mortalidade Infantil , Psiconeuroimunologia , Família , Feminino , Humanos , Lactente , Gravidez , Estudos Prospectivos , Estados Unidos
14.
Multimedia | Recursos Multimídia | ID: multimedia-7995

RESUMO

Evidências da ação de medicamento homeopático no sistema imune. Webinar Fortalecimiento del sistema inmune: Contribuciones de las MTCI en el contexto de la pandemia por COVID-19. 31 Octubre 2020.


Assuntos
Sistema Imunitário , Homeopatia , Psiconeuroimunologia , Medicamento Homeopático
19.
Rev. Esc. Enferm. USP ; 55: e20210159, 2021. graf
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1340706

RESUMO

ABSTRACT Objective: To discuss the evolution of research in cancer psychoneuroimmunology, the advances in the management of neuropsychological symptom clusters and their interface with mid-range theories, and practical applications in Nursing. Method: This is a theoretical-reflective study anchored in recent literature, as well as in the critical analysis of the authors. Results: This is a promising field of investigation, which emphasizes the complexity and interaction of symptoms, the interrelationships among them, the factors influencing them, and their consequences. Subsidized by mid-range theories in Nursing, such as the Theory of Unpleasant Symptoms and the Theory of Symptom Management, analyses of these interrelationships support Oncology Nursing diagnoses and interventions. Conclusion: An innovative approach is proposed to qualify Oncology Nursing care based on the integration of recent advances in cancer psychoneuroimmunology, Nursing mid-range theories, and practical tools such as health coaching. The approach proposed may strengthen clinical nursing practice in the management of neuropsychological symptom clusters in oncology and shall be integrated into decision-making during cancer treatment, favoring person-centered care.


RESUMEN Objetivo: Discutir la evolución de las investigaciones en psiconeuroinmunología del cáncer, los avances en el manejo de los clusters de síntomas neuropsicológicos y su interface con teorías de rango medio y aplicaciones prácticas por la Enfermería. Método: Estudio teórico-reflexivo ancorado en literatura reciente, así como en el análisis crítico de los autores. Resultados: Este es un campo promisor de investigación, que tiene énfasis en la complejidad y la interacción de los síntomas, las interrelaciones entre ellos, los factores que los influyen y sus consecuencias. Subsidiadas por teorías de rango medio en Enfermería, como la Teoría de los Síntomas Desagradables y la Teoría del Manejo de Síntomas, análisis de estas interrelaciones corroboran los diagnósticos y las intervenciones de Enfermería en Oncología. Consideraciones Finales: Se ha propuesto un abordaje innovador para calificar el cuidado de Enfermería Oncológica a partir de la integración de avances recientes en psiconeuroinmunología del cáncer, teorías de rango medio de Enfermería y herramientas prácticas como coaching de salud. El abordaje propuesto puede fortalecer la práctica clínica de Enfermería en la gestión de los clusters de síntomas neuropsicológicos en oncología y debe ser integrado en las acciones y decisiones durante el tratamiento oncológico que favorezcan el cuidado centrado en las personas.


RESUMO Objetivo: Discutir a evolução das pesquisas em psiconeuroimunologia do câncer, os avanços no manejo dos clusters de sintomas neuropsicológicos e sua interface com teorias de médio alcance e aplicações práticas pela Enfermagem. Método: Estudo teórico-reflexivo ancorado em literatura recente, bem como na análise crítica dos autores. Resultados: Este é um campo promissor de investigação, que enfatiza a complexidade e a interação dos sintomas, as inter-relações entre os mesmos, os fatores que os influenciam e suas consequências. Subsidiadas por teorias de médio alcance em Enfermagem, como a Teoria dos Sintomas Desagradáveis e a Teoria de Gerenciamento de Sintomas, análises destas inter-relações corroboram os diagnósticos e as intervenções de Enfermagem em Oncologia. Conclusão: Propõe-se uma abordagem inovadora para qualificar o cuidado de Enfermagem Oncológica a partir da integração de avanços recentes em psiconeuroimunologia do câncer, teorias de médio alcance de Enfermagem, e ferramentas práticas como coaching de saúde. A abordagem proposta pode fortalecer a prática clínica da Enfermagem no manejo dos clusters de sintomas neuropsicológicos em oncologia e deve ser integrada na tomada de decisões durante o tratamento oncológico, favorecendo o cuidado centrado na pessoa.


Assuntos
Enfermagem Oncológica , Psiconeuroimunologia , Neuroimunomodulação , Sintomas Concomitantes , Tutoria , Neoplasias
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