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1.
Infectio ; 25(4): 262-269, oct.-dic. 2021. tab, graf
Artigo em Inglês | LILACS, COLNAL | ID: biblio-1286720

RESUMO

Abstract Objective: To analyse the clinic characteristics, risk factors and evolution of the first cohort of hospitalised patients with confirmed infection by COVID-19 in 5 Colombian institutions. Materials and methods: Is a retrospective observational study of consecutive hospitalized patients with a diagnosis of COVID-19 confirmed from March 01 to May 30, 2020 in Colombia. Results: A total of 44 patients were included. The median age was 62 years. 43.2% had a history of smoking, while 69.8% were overweight or obese. 88.6% had at least one comorbidity and 52.3% had three or more comorbidities. Hypertension and dyslipidaemia were the most frequent comorbidities (40.9% and 34.1%, respectively). The 30-day mortality rate was 47.7% with a median of 11 days. The composite outcome occurred in the 36.4%. The biomarkers associated with mor tality risk included troponin higher than 14 ng/L (RR: 5.25; 95% CI 1.37-20.1, p = 0.004) and D-dimer higher than 1000 ng/ml (RR: 3.0; 95% CI 1.4-6.3, p = 0.008). Conclusions: The clinical course of SARS-CoV-2 infection in hospitalized Colombian was characterised by a more advanced stage of the infection.


Resumen Objetivo: Analizar las características, clínicas, factores de riesgo, y la evolución de pacientes hospitalizados con infección confirmada por COVID-19 en 5 Institu ciones de Colombia. Material y método: Es un estudio observacional retrospectivo de pacientes consecutivos hospitalizados con diagnóstico de COVID-19 confirmado entre 01 de Febrero de 2020 y 30 de Mayo de 2020 en Colombia. Resultados: Un total de 44 pacientes fueron incluidos. La mediana de edad fue de 62 años y la mayoría del sexo masculino. El 43.2% tenían historia de tabaquismo, mientras que el 69.8% tenían sobrepeso u obesidad. El 88.6% tenían al menos una comorbilidad y el 52.3% tenían tres o más comorbilidades. La hipertensión arterial fue la comorbilidad más frecuente (40.9%), seguido de la dislipidemia (34.1%). La tasa de letalidad a 30 días fue de 47.7% y ocurrió con una mediana de 11 días. El 36.4% presentó el desenlace compuesto. Los biomarcadores asociados con el riesgo de muerte fue troponina > 14 ng/mL (RR:5.25, IC95% 1.37-20.1, p=0.004) y dímero D mayor a 1000 mg/dL (RR: 3.0, IC95% 1.4-6.3, p=0.008). Conclusiones: El curso clínico de la infección por SARS-CoV-2 en colombianos hospitalizados fue un estadio más avanzado de la infección.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Biomarcadores , COVID-19 , Pacientes , Tabagismo , Comorbidade , Risco , Fatores de Risco , Mortalidade , Colômbia , Sobrepeso , Cursos , Infecções , Obesidade
3.
Recurso na Internet em Inglês, Português | LIS - Localizador de Informação em Saúde | ID: lis-48524

RESUMO

Atualmente, uma em cada três pessoas está com sobrepeso ou obesidade e uma em cada nove pessoas passa fome no mundo.


Assuntos
Sobrepeso , Obesidade , Obesidade Pediátrica
4.
Acta Orthop Traumatol Turc ; 55(5): 435-438, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34730531

RESUMO

OBJECTIVE: The aim of this study was to determine the clinical usefulness of the Ottawa Ankle Rules (OAR) in overweight and obese patients compared to the general population. METHODS: In this prospective cross-sectional study, 935 adult patients (453 female, 482 male; mean age = 57.2 ± 20.9) admitted to the emergency department following an acute ankle injury (<3 days) secondary to low energy-trauma were included. All the patients were examined based on a standardized protocol, including age, Body-Mass Index (BMI), OAR, and presence of ankle fracture. As accuracy indicators, sensitivity, specificity, positive and negative predictive values of OAR were calculated. RESULTS: Of all patients, 790 (84.5%) were normal weighted, 107 (11.5%) were overweight, and 38 (4%) were obese. While OAR was negative in 58.8% of patients, 41.2% of patients met OAR. The sensitivity of OAR in the normal weighted population was significantly higher than obese and overweight groups (P < 0.01). The specificity of OAR in the normal weighted population was significantly lower than overweight and obese groups (P < 0.01). The accuracy of OAR in the overweight group was 82.7% and significantly higher compared with the normal weighted population (62.8%) (P < 0.01). CONCLUSION: We do not recommend OAR as a screening tool to be used safely in patients with higher BMI because of its lower sensitivity in this population. In this specific patient population, these rules should be implemented carefully, and radiography should be evaluated meticulously not to miss a fracture. LEVEL OF EVIDENCE: Level IV, Cross Sectional Study.


Assuntos
Fraturas do Tornozelo , Traumatismos do Tornozelo , Fraturas Ósseas , Adulto , Idoso , Tornozelo , Fraturas do Tornozelo/diagnóstico por imagem , Traumatismos do Tornozelo/diagnóstico por imagem , Estudos Transversais , Serviço Hospitalar de Emergência , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade/complicações , Obesidade/diagnóstico , Obesidade/epidemiologia , Sobrepeso/diagnóstico , Sobrepeso/epidemiologia , Estudos Prospectivos , Sensibilidade e Especificidade
5.
Zhonghua Liu Xing Bing Xue Za Zhi ; 42(7): 1160-1166, 2021 Jul 10.
Artigo em Chinês | MEDLINE | ID: mdl-34814525

RESUMO

Objective: To describe the differences in body mass index (BMI) distribution in adult twins registered in Chinese National Twin Registry (CNTR), and provide evidence for the risk factor analysis and prevention and control of overweight or obesity. Methods: A total of 32 725 twin pairs aged 18 years and above who completed the questionnaire survey during 2010-2018 and had complete registered information in CNTR and normal body weight and length were included in the analysis on the population and region specific distributions of BMI of twin pairs and the difference in BMI in twin pairs. Results: The twin pairs included in the analysis were aged (34.6±12.4) years, the twin pairs of same gender accounted for 79.7%. The average BMI was 22.5 kg/m2. The overall prevalence of obesity and overweight was 4.9% and 23.7%, respectively. Participants who were men, 50-59 years old, married, had lower education level, and lived in northern China had higher overweight rate and obesity rate (P<0.001). The difference in overweight or obesity prevalence between monozygotic (MZ) twin pars and dizygotic (DZ) twin pairs was not significant, but firstborn twin pairs had slightly higher rates of overweight and obesity than later-born twin pairs (P<0.05). The analysis in same gender-twin pairs indicated that the difference in BMI was associated with age (trend test: P<0.001), and the difference was more obvious in DZ twin pair in MZ pair and this difference increased with age. The concordant rate of BMI was higher in MZ twin pairs than DZ twin pairs (P<0.05). Conclusion: The distribution of BMI of twin pairs varied with population and region and BMI varied with age due to its genetic nature.


Assuntos
Gêmeos Dizigóticos , Gêmeos Monozigóticos , Índice de Massa Corporal , China/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Sobrepeso/epidemiologia
6.
Zhonghua Liu Xing Bing Xue Za Zhi ; 42(10): 1809-1816, 2021 Oct 10.
Artigo em Chinês | MEDLINE | ID: mdl-34814616

RESUMO

Objective: To identify age and gender standardized body mass index among children and adolescents and explore their associations with high blood pressure (HBP) in late adolescence. Methods: The current study was based on the Health Promotion Program for Children and Adolescents, school-based surveillance successively conducted from 2012 to 2019 in Suzhou, China. A total of 11 812 children and adolescents aged 16-18 years, who had ≥4 examination records during 2012-2018 and were also involved in a surveillance program in 2019, were included. Latent class growth mixture modeling was used to identify the BMI-Z trajectories in different genders, and multivariate logistic regression was used to analyze the associations between different BMI-Z trajectories and risk of HBP in late adolescence. Results: Six distinct BMI-Z trajectories were determined for both genders:thin, slightly thin,standard, declining, overweight, and obese. Compared with the regular group, the obesity group had 94.0% (OR=1.94, 95%CI: 1.43-2.63) and 107.0% (OR=2.07, 95%CI: 1.33-3.22) increased risk of developing HBP in late adolescence in boys and girls, respectively. However, a neutral association was found between the descending group and HBP in late adolescence. Conclusions: Persistent obesity in children may increase the risk of HBP in their late adolescence. If an obese child restores normal weight before late adolescence, the risk of HBP may reduce.


Assuntos
Hipertensão , Obesidade Pediátrica , Adolescente , Pressão Sanguínea , Índice de Massa Corporal , Criança , Feminino , Humanos , Hipertensão/epidemiologia , Modelos Logísticos , Masculino , Sobrepeso , Obesidade Pediátrica/epidemiologia
7.
Harefuah ; 160(11): 732-739, 2021 Nov.
Artigo em Hebraico | MEDLINE | ID: mdl-34817140

RESUMO

INTRODUCTION: Childhood and adolescent obesity are significant global public health concerns. In recent decades, the Israel Medical Corps, in collaboration with other health organizations, initiated studies regarding the obesity epidemic in Israel, characterized specific groups that are at-risk for obesity and analyzed the short- and the long- term risks for associated medical conditions among those with obesity. According to these data, adolescent obesity and severe obesity prevalence have increased by 4- and 20-fold in the last decades in Israel, respectively. Low socioeconomic status, low level of education and low cognitive function were associated with a higher risk for obesity. Adolescents with obesity are at greater risk than those with normal weight for hyperhidrosis, asthma, different orthopedic abnormalities, hypertension and type 2 diabetes. A longitudinal study that followed the adolescents for 11 years has demonstrated a significant risk for adolescents with obesity for type 2 diabetes with hazard ratios (HRs) of 13 to 45, depending on sex and obesity degree. Longitudinal studies reported hazard ratios of 7 for end-stage chronic kidney disease, 1.3 for cancer, 3 for ischemic stroke and 7 for coronary heart disease in adulthood for adolescents with obesity compared to those with normal weight. Adolescents with overweight and obesity had greater risk for all-cause mortality in adulthood. Given the alarming increase in the prevalence of obesity and the significant short- and long- term consequences of adolescent obesity, the burden of the economic and clinical services on the healthcare system is expected to rise.


Assuntos
Diabetes Mellitus Tipo 2 , Obesidade Pediátrica , Adolescente , Adulto , Índice de Massa Corporal , Criança , Humanos , Israel/epidemiologia , Estudos Longitudinais , Sobrepeso , Obesidade Pediátrica/epidemiologia
8.
Nutr J ; 20(1): 91, 2021 11 13.
Artigo em Inglês | MEDLINE | ID: mdl-34774052

RESUMO

BACKGROUND: The dietary spice Curcuma longa, also known as turmeric, has various biological effects. Both a water extract and a supercritical carbon dioxide extract of C. longa showed anti-inflammatory activities in animal studies. However, the anti-inflammatory effect in humans of a mixture of these two C. longa extracts (CLE) is poorly understood. Therefore, we investigated the effect of CLE containing anti-inflammatory turmeronols on chronic inflammation and general health. METHODS: We performed a randomized, double-blind, placebo-controlled study in healthy subjects aged 50 to 69 years with overweight. Participants took two capsules containing CLE (CLE group, n = 45) or two placebo capsules (placebo group, n = 45) daily for 12 weeks, and serum inflammatory markers were measured. Participants also completed two questionnaires: the Medical Outcomes Study (MOS) 36-Item Short-Form Health Survey (SF-36) and the Profile of Mood States (POMS) scale. Treatment effects were analyzed by two way analysis of variance followed by a t test (significance level, p <  0.05). RESULTS: After the intervention, the CLE group had a significantly lower body weight (p <  0.05) and body mass index (p < 0.05) than the placebo group and significantly lower serum levels of C-reactive protein (p < 0.05) and complement component 3 (p < 0.05). In addition, the CLE group showed significant improvement of the MOS SF-36 mental health score (p < 0.05) and POMS anger-hostility score (p < 0.05). CONCLUSION: CLE may ameliorate chronic low-grade inflammation and thus help to improve mental health and mood disturbance. TRIAL REGISTRATION: UMIN-CTR, UMIN000037370. Registered 14 July 2019, https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000042607.


Assuntos
Curcuma , Saúde Mental , Voluntários Saudáveis , Humanos , Sobrepeso/tratamento farmacológico , Extratos Vegetais
9.
Trials ; 22(1): 801, 2021 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-34774104

RESUMO

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is one of the main causes of chronic liver disease worldwide. Flavonoids, a group of natural compounds, have garnered a great deal of attention in the management of NAFLD because of their profitable effects on glucose and lipid metabolism, inflammation, and oxidative stress which are the pivotal pathophysiological pathways in NAFLD. Naringenin is a citrus-derived flavonoid with a broad spectrum of potential biological effects including anti-inflammatory and antioxidant properties, which may exert protective effects against NAFLD. The present clinical trial aims to examine the efficacy of naringenin supplementation on plasma adiponectin and neurogulin-4 (NRG-4) concentrations, metabolic parameters, and liver function indices in overweight/obese patients with NAFLD. METHODS AND ANALYSIS: This is a double-blind, randomized, placebo-controlled clinical study that will investigate the impacts of naringenin supplementation in overweight/obese patients with NAFLD. Liver ultrasonography will be applied to diagnose NAFLD. Forty-four eligible overweight/obese subjects with NAFLD will be selected and randomly assigned to receive naringenin capsules or identical placebo (each capsule contains 100 mg of naringenin or cellulose), twice daily for 4 weeks. Participants will be asked to remain on their usual diet and physical activity. Safety of naringenin supplementation was confirmed by the study pharmacist. The primary outcome of this study is changes in adiponectin circulating levels. The secondary outcomes include changes in NRG-4 levels, liver function indices, metabolic parameters, body weight, body mass index (BMI), waist circumference (WC), blood pressure, and hematological parameters. Statistical analysis will be conducted using the SPSS software (version 25), and P value less than 0.05 will be regarded as statistically significant. DISCUSSION: We hypothesize that naringenin administration may be useful for treating NAFLD by modulating energy balance, glucose and lipid metabolism, oxidative stress, and inflammation through different mechanisms. The current trial will exhibit the effects of naringenin, whether negative or positive, on NAFLD status. ETHICAL ASPECTS: The current trial received approval from the Medical Ethics Committee of Tehran University of Medical Sciences, Tehran, Iran (IR.TUMS.MEDICNE.REC.1399.439). TRIAL REGISTRATION: Iranian Registry of Clinical Trials IRCT201311250155336N12 . Registered on 6 June 2020.


Assuntos
Hepatopatia Gordurosa não Alcoólica , Suplementos Nutricionais , Método Duplo-Cego , Flavanonas , Humanos , Irã (Geográfico) , Hepatopatia Gordurosa não Alcoólica/diagnóstico por imagem , Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico , Obesidade/complicações , Obesidade/diagnóstico , Obesidade/tratamento farmacológico , Sobrepeso/tratamento farmacológico , Ensaios Clínicos Controlados Aleatórios como Assunto
10.
J Assoc Physicians India ; 69(10): 11-12, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34781655

RESUMO

INTRODUCTION: Adolescence is the transitional period between childhood and adulthood when new health behaviors are laid down, which may track in to adulthood and have lifelong impact. Global trends show that these NCD-related behaviors are gradually rising among young people, and that they establish patterns of behavior that persist throughout life and are often hard to alter. OBJECTIVE: To find out the prevalence and socio demographic predictors of risk factors of non communicable diseases among adolescents of a rural area Methods: A community based cross sectional study was conducted among 365 adolescents residing in a rural area of Siliguri subdivision. They were interviewed and measurements were taken using standard procedure. RESULTS: The prevalence of behavioural factors for NCDs like tobacco use, alcohol use, unhealthy diet, physically inactivity was 18.4%, 4.7%, 87.1% and 23.0% respectively; metabolic risk factors like overweight, hypertension, and abdominal obesity 28.5%, 17.5%, 1.4% respectively. After adjustment, the odds of behavioural and metabolic risk factors were found highest among the males, participants whose mothers were not working and those who belonged to Hindu families and lower socioeconomic class. CONCLUSION: The proportion of risk factors of non communicable diseases among the rural adolescents was quite high'. Given the associated health problems and costs, non communicable diseases have become an issue of serious concern.


Assuntos
Hipertensão , Doenças não Transmissíveis , Adolescente , Adulto , Criança , Estudos Transversais , Humanos , Masculino , Doenças não Transmissíveis/epidemiologia , Sobrepeso , Prevalência , Fatores de Risco , População Rural
11.
Int J Public Health ; 66: 601591, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34744567

RESUMO

Objectives: The present study has examined the patterns and possible correlates of coexisting morbidities among women aged 15-49 years based on biomarker measurement data at the national level in India. Methods: National Family Health Survey conducted during 2015-16 used in the present study. Simple disease count approach was used to calculate the multimorbidity among women. Multinomial logistic regression was applied to analyze the predictors of multimorbidity among women. Results: Almost 30% of the women had any of the selected morbidity and 9% of them had two or more morbidities. Hypertension and overweight combination (3%) was the most prevalent among women. The risk of having two or more morbidities was predominantly high among women aged above 30 years, low educated women, women from the wealthier group, ever-married women and women who were consuming tobacco as compared to their counterparts. Conclusions: From the policy perspective, the identification of groups of women vulnerable to multimorbidity will help in the selection of programmatic focus and preventive public health intervention in adult phase to reduce the multimorbidity burden among women in old ages.


Assuntos
Multimorbidade , Adolescente , Adulto , Feminino , Humanos , Hipertensão/epidemiologia , Índia/epidemiologia , Pessoa de Meia-Idade , Sobrepeso/epidemiologia , Prevalência , Fatores de Risco , Fatores Socioeconômicos , Adulto Jovem
12.
Int J Public Health ; 66: 633183, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34744585

RESUMO

Objectives: Obesity is a risk factor for several chronic conditions, including sleep disorders. We aimed to analyze the relationship between BMI, body fat percentage (FAT%), hip and waist circumference, and weight on the duration of nocturnal sleep. Methods: This study was part of the MASHAD cohort study. In all participants BMI and FAT% were measured. BMI was used to categorize individuals as obese, overweight, and normal subjects. FAT% was used to categorize individuals into tertile: tertile 1 (low) < 27.5, tertile 2 (medium) 27.5-41, and tertile 3 (high) > 41. The level of nightly sleep duration was categorized into three groups: <6, 6-8 (reference group), and >8 h. Results: There was a significant inverse association between body weight and duration of sleep (p < 0.05). Obese and overweight participants had 1.152 OR (CI:1.083-1.225) and 1.126 OR (CI:1.063-1.194) for a short duration of nocturnal sleep, respectively, relative to those with a normal BMI. Conclusion: BMI was an independent determinant of nocturnal sleep duration; obesity and overweight may have negative consequences on sleep duration. Weight control should be considered as a factor in adjusting sleep quality.


Assuntos
Obesidade , Sobrepeso , Distúrbios do Início e da Manutenção do Sono , Adulto , Estudos Transversais , Humanos , Irã (Geográfico)/epidemiologia , Obesidade/epidemiologia , Sobrepeso/epidemiologia , Fatores de Risco , Distúrbios do Início e da Manutenção do Sono/epidemiologia
13.
Int J Public Health ; 66: 1604101, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34744598

RESUMO

Objective: To identify the socio-demographic risk factors that are associated with adult Body Mass Index. Methods: We apply probit and ordinal probit models to a sample of 3,803 adults aged 20 and above from the 2016/17 round of the Suriname Survey of Living Conditions. Results: Women, the elderly, and couples who are either married and/or living together are more likely to be obese or overweight. This is also true for individuals who have chronic illnesses. We also find that individuals who engage in a sport or in other forms of exercise, even if modest, have lower odds of being overweight or obese. Interestingly, our findings indicate that individuals who benefit from government social safety net programs are less likely to be associated with being overweight or obese. Conclusion: Obesity could become a serious public health issue if not addressed appropriately. Policymakers should promptly develop a national strategy to help health care systems cope with the outcomes of obesity and to tackle the risk factors that have the greatest impacts on individual Body Mass Index.


Assuntos
Obesidade , Sobrepeso , Adulto , Idoso , Índice de Massa Corporal , Feminino , Humanos , Masculino , Obesidade/epidemiologia , Sobrepeso/epidemiologia , Fatores de Risco , Suriname/epidemiologia
15.
Front Public Health ; 9: 749302, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34746084

RESUMO

Background: Few comprehensive lifestyle intervention programmes have been investigated on overweight and obese adults in China. This study was to evaluate the effect of a 36-month weight management programme on weight loss and its maintenance among overweight and obese patients in Ningbo, China. Methods: Adults with BMI ≥24kg/m 2 enrolled in this programme, including nutritional, physical activity, psychological and endocrinological counselling sessions, from July 2015 to January 2020. Adults participated in face-to-face counselling sessions and group-based education. Then, participants joined 21-day intensive programme using Bohe health APP and WeChat group to get personal advice of nutrition and lifestyle. In the end, participants were requested to join 33-month follow-ups including face-to-face counselling and personal advice on WeChat group. The main outcome was to evaluate the changes in weight at each followup from baseline weight. Results: In total, 692 adults participated in this entire weight management programme. During follow-ups, 579, 475, 299, 219, and 135 adults participated at 3, 6, 12, 24, and 36 months, respectively. All participants had a significant initial weight loss at 3 months, then maintained the weight loss during 33-month follow-ups. At 36 months, 11.0%, 6.4%, and 3.5% of all participants achieved 5%, 10%, and 15% weight loss from the baseline weight, respectively. Adjusted weight at 36 months was significantly reduced from the baseline weight in both sex (-7.2 kg). Conclusion: This weight management programme is suggested to benefit to reduce initial body weight and maintain long-term weight loss among overweight and obese adults.


Assuntos
Programas de Redução de Peso , Adulto , China , Humanos , Obesidade/terapia , Sobrepeso/terapia , Perda de Peso
16.
Front Public Health ; 9: 715956, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34760860

RESUMO

Background: The shift in disease patterns has been connected with increased body weight burden, becoming a major public health concern in South Africa, as previous studies have assessed overweight or obesity among certain populations. However, little is known about bodyweight burden (underweight, overweight, and obesity) among women aged 15-49 years. Therefore, this study was conducted to identify the prevalence and its associated socio-demographic correlates of bodyweight categories among women of reproductive age in South Africa. Methods: The present study used the South Africa Demographic Health Survey (2016 SADHS) data for 2016. A total of 3,263 women of reproductive age were included in the analysis. Both bivariable and multivariable logistics regressions were performed to determine the prevalence and socio-demographic correlates of bodyweight categories among women in South Africa. Thus, this study used the criteria of the WHO standard body mass index (BMI) cut-offs to classify bodyweight categories. The odds ratios (ORs) with 95% CIs were estimated for potential determinants included in the final model. Results: The overall prevalence of body weight burden was 66.5%, with 4.9% underweight, 27.1% overweight, and 34.5% obese (p < 0.05). The identified factors associated with underweight among women of reproductive age were those from "other" population group [adjusted odds ratio (AOR) 2.65: 95% CI 1.40-5.00], rural residence (AOR 1.23: 95% CI 0.75-2.02), and Northern Cape Province (AOR 1.58: 95% CI 0.65-3.87). For overweight/obese, the main factors were those aged 45-49 years (AOR 10.73: 95% CI 7.41-15.52), tertiary education (AOR 1.41: 95% CI 0.97-2.03), and residing in Eastern Cape (AOR 1.27: 95% CI 0.82-1.99) and KwaZulu-Natal Provinces (AOR 1.20: 95% CI 0.78-1.84). Conclusion: The findings presented in this study indicate the concurrence of underweight and overweight/obese among women aged 15-49 years in South Africa. Despite underweight prevalence being on the decline, yet overweight/obese is increasing over time. The health implication of body weight burden needs rapid and effective interventions, focusing on factors such as rural, education, population group, older age 45-49 years, and Provinces (Northern Cape, Eastern Cape, and KwaZulu-Natal) - the high-risk groups identified herein are of most importance to curb the growing burden among South African women of reproductive age.


Assuntos
Sobrepeso , Idoso , Estudos Transversais , Feminino , Humanos , Sobrepeso/epidemiologia , Prevalência , Fatores de Risco , África do Sul/epidemiologia
17.
Artigo em Inglês | MEDLINE | ID: mdl-34769782

RESUMO

Obesity has become a serious public health problem worldwide and is linked to an increased risk of non-communicable diseases (NCDs). Poor self-perception of body weight is postulated to play a negative role in curbing increased rates of obesity. This study investigated the views of own body weight and perceived risk of developing NCDs in South African adults. This was a community-based quantitative study. Descriptive statistics were used, and logistic regression analysis was conducted on the data. A total of 1050 respondents took part in the study. Of the 161 respondents who perceived themselves to be normal weight, 98.8% (n = 159) misperceived their body weight. The majority of respondents (>90%) who were overweight according to the calculated BMI perceived no risk of developing obesity-related diseases. Most of the respondents, 46% (n = 253), believed that body weight was influenced by heredity. The method used for weight loss by 57% (n = 173) of the respondents was exercising at home. There was a statistically significant association between Body Mass Index (BMI), employment status, risk of developing diabetes, and body weight misperception (p < 0.05). Misperception of body weight was common among the study respondents and may influence weight control intervention strategies. Health promotion targeting personal behaviour, such as body weight self-perception, is crucial in supporting targeted strategies to address obesity in South Africa.


Assuntos
Doenças não Transmissíveis , Adulto , Imagem Corporal , Índice de Massa Corporal , Peso Corporal , Humanos , Obesidade/epidemiologia , Sobrepeso
18.
BMC Gastroenterol ; 21(1): 431, 2021 Nov 18.
Artigo em Inglês | MEDLINE | ID: mdl-34794374

RESUMO

PURPOSE: The aim of the study is to explore the independent association of free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) with hepatic steatosis and insulin resistance. METHODS: A cross-sectional study of 88 overweight/obese adults who underwent anthropometric measurements [BMI, waist circumference (WC) and waist-to-height ratio (WHtR)], hepatic steatosis assessment (FibroScan) and thyroid-related hormones tests was conducted from 2018 to 2020 in Xiamen, China. RESULTS: Subjects with increasing tertiles of FT3 showed significantly higher levels of controlled attenuation parameter (CAP) ((295.4 ± 44.1, 290.1 ± 68.2 and 331.7 ± 43.6 (dB/m) for tertile 1-3, respectively, p = 0.007) and fatty liver index (FLI) score (47.7 (33.9-60.8), 61.5 (45.1-88.9) and 90.5 (84.5-94.8), respectively, p < 0.001). FT3 significantly and positively correlated with obesity index (BMI, WC, and WHtR), homeostatic model assessment of insulin resistance (HOMA-IR) and hepatic steatosis (CAP and FLI). Multivariable linear regression analyses with adjustment for potential confounding factors showed FT3 was independently associated with BMI (regression coefficient (ß (95%CI): 0.024 (0.004-0.043), p = 0.020), HOMA-IR (ß (95%CI): 0.091 (0.007-0.174), p = 0.034), CAP (ß (95%CI): 25.45 (2.59-48.31), p = 0.030) and FLI (ß (95%CI): 0.121 (0.049-0.194), p = 0.001). Neither FT4 nor TSH was significantly associated with any indicators of obesity, insulin resistance or hepatic steatosis. CONCLUSIONS: Increased FT3, but not FT4 or TSH, was independently associated with higher risks of hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults. Trial registration Registration is not applicable for our study.


Assuntos
Fígado Gorduroso , Resistência à Insulina , Adulto , China , Estudos Transversais , Humanos , Obesidade/complicações , Sobrepeso/complicações , Glândula Tireoide , Hormônios Tireóideos , Tireotropina , Tiroxina , Tri-Iodotironina
19.
Artigo em Inglês | MEDLINE | ID: mdl-34769772

RESUMO

Overweight can be an additional problem in patients admitted to hospital. OBJECTIVE: To analyze gender differences in pre-admission dietary habits and physical exercise and in HRQoL at hospital discharge among hospitalized adults with overweight. METHODS: Cross-sectional study in non-diabetic patients enrolled in a clinical trial with body mass index (BMI) ≥ 25 Kg/m2 at admission. Bivariate analyses used Pearson's chi-square test and Fisher's exact test for qualitative variables and the Mann-Whitney test for numerical variables. RESULTS: The study included 148 males and 127 females. At admission, women had higher BMI (p = 0.016) than men and a larger percentage consumed drugs for depression (p = 0.030) and anxiety (p = 0.049), and followed a religion-based diet (p = 0.022). Pre-admission, women had healthier habits related to dietary caloric intake (p = 0.009) and greater adherence to recommendations for a healthy diet (p = 0.001). At discharge, women described worse self-perceived health (p = 0.044) and greater pain/discomfort (p = 0.004) in comparison to men. CONCLUSIONS: Pre-admission, women had better habits related to a healthy diet and did not differ from men in habits related to physical exercise but had a higher BMI. At discharge, women reported worse self-perceived health and greater pain/discomfort. These differences should be considered for the adequate clinical management of patients with overweight.


Assuntos
Obesidade , Qualidade de Vida , Adulto , Índice de Massa Corporal , Estudos Transversais , Dieta , Exercício Físico , Comportamento Alimentar , Feminino , Humanos , Masculino , Sobrepeso/epidemiologia
20.
Acta Cir Bras ; 36(9): e360905, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34755765

RESUMO

PURPOSE: To evaluate the morphological, biochemical, and histological effects of aqueous extracts of peanut (skinless and added to 1% skin) in Swiss mice submitted to a high-fat diet. METHODS: Forty male Swiss mice were divided into four groups (n=10 per group): GI) normocaloric diet; GII) high-fat diet; GIII) high-fat diet + 0.5 mL of peanut extract; GIV) high-fat diet + 0.5 mL of peanut extract + 1% peanut skin. The animals were weighed weekly and euthanized after 12 weeks for histopathological and biochemical analyses. The study was approved by the Animal Use Ethics Committee. RESULTS: The animals in the GIV group had higher body weight when compared to the other ones. Increase in total cholesterol in GIII, increase in blood glucose in groups GII, GIII and GIV, decrease in serum low-density lipoprotein (LDL) concentration in groups GI and GIV and increase in serum concentration of C-reactive protein in GII were seen. The presence of vacuolar fat deposits was found in animal livers from GII. CONCLUSIONS: The extracts improved the plasma concentrations of animals that received a high-fat diet, including preventing morphological damage to liver tissue. These benefits were enhanced by the association of peanut shells with the extract.


Assuntos
Arachis , Dieta Hiperlipídica , Animais , Dieta Hiperlipídica/efeitos adversos , Fígado , Camundongos , Sobrepeso , Extratos Vegetais/farmacologia
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