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1.
BMC Ophthalmol ; 21(1): 376, 2021 Oct 23.
Artigo em Inglês | MEDLINE | ID: mdl-34688252

RESUMO

BACKGROUND: In August 2020, we found one case of thelazia callipaeda infection during phacoemulsification cataract surgery. This maybe the first report for thelazia callipaeda discovered during phacoemulsification cataract surgery in China. CASE PRESENTATION: An 85 years old farmer was found thelazia callipaeda infection during phacoemulsification cataract surgery. The patient admitted whose foreign body sensation was often found in the right eye in recent 2 months. The worm was then taken out with ophthalmic forceps and put into sterile normal saline. The worm was sent to the Eye Institute of Shandong University of Traditional Chinese Medicine for identification. After identification, the worm was regarded as the male thelazia callipaeda. The head is blunt and round, the tail end curls to the abdomen, and the long copulation spines protrudes from the cloaca. The conjunctival sac was washed carefully with a large amount of Sodium Lactate Ringer 's Solution. After operation, antibiotics, pranoprofen eye drops, and tobramycin dexamethasone eye drops were further applied. After continuous examination of conjunctival sac for 2 weeks, the patient's visual acuity maintained 20/20, confirming that there was no residual thelazia. CONCLUSIONS: This report highlights the physician should ask the patient's history carefully before operation and it is necessary to strengthen health publicity and education, maintaining clean environment and keeping personal eye hygiene.


Assuntos
Catarata , Facoemulsificação , Infecções por Spirurida , Thelazioidea , Idoso de 80 Anos ou mais , Animais , Catarata/complicações , China , Humanos , Masculino , Facoemulsificação/efeitos adversos , Infecções por Spirurida/diagnóstico
3.
Folia Parasitol (Praha) ; 682021 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-34152290

RESUMO

Based on light and electron microscopical studies, a new nematode parasite, Echinocephalus inserratus sp. n. (Spirurida: Gnathostomatidae), is described from the spiral valve of the broad cowtail stingray Pastinachus ater (Macleay) (Dasyatidae, Myliobatiformes) from off New Caledonia. The new species is morphologically and biometrically most similar to Echinocephalus overstreeti Deardorff et Ko, 1983, differing from it mainly in the absence of serrations on the posterior parts of pseudolabia and on interlabia, and in having a longer gubernaculum (150-299 µm long). Morphologically unidentifiable, mostly encapsulated larvae of Echinocephalus spp. were recorded from the following six species of teleost fishes collected in New Caledonian waters, serving as paratenic hosts: Perciformes: Acanthopagrus berda (Forsskål) (Sparidae) and Nemipterus furcosus (Valenciennes) (Nemipteridae); Tetraodontiformes: Abalistes stellatus (Anonymous), Pseudobalistes fuscus (Bloch et Schneider) (both Balistidae), Lagocephalus sceleratus (Gmelin) (Tetraodontidae) and Aluterus monoceros (Linnaeus) (Monacanthidae). Co-parasitising larvae of Ascarophis sp. and Hysterothylacium sp. were also collected from P. fuscus. All these findings represent new host and geographical records. A key to valid species of Echinocephalus Molin, 1858 is provided.


Assuntos
Doenças dos Peixes/epidemiologia , Interações Hospedeiro-Parasita , Rajidae , Infecções por Spirurida/veterinária , Thelazioidea/classificação , Animais , Feminino , Doenças dos Peixes/parasitologia , Larva/anatomia & histologia , Larva/classificação , Larva/crescimento & desenvolvimento , Larva/ultraestrutura , Masculino , Microscopia Eletrônica de Varredura/veterinária , Nova Caledônia/epidemiologia , Prevalência , Infecções por Spirurida/epidemiologia , Infecções por Spirurida/parasitologia , Thelazioidea/anatomia & histologia , Thelazioidea/crescimento & desenvolvimento , Thelazioidea/ultraestrutura
4.
Emerg Infect Dis ; 27(7): 1923-1926, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-33979567

RESUMO

We report a case of autochthonous infection of the eye worm Thelazia callipaeda in a dog in the northeastern United States. Integrated morphologic identification and molecular diagnosis confirmed the species. Phylogenetic analysis suggested introduction from Europe. The zoonotic potential of this parasite warrants broader surveillance and increased awareness among physicians and veterinarians.


Assuntos
Doenças do Cão , Infecções por Spirurida , Thelazioidea , Animais , Cães , Europa (Continente) , Humanos , New England , New York , Filogenia
5.
Parasitol Int ; 84: 102381, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33975001

RESUMO

Spirocerca lupi is a common parasitic nematode associated with esophageal cancer of canids. Recent surveys have revealed an increasing number of canids infected with Spirocerca spp. in Africa, the Americas, Europe and Western Asia, and described a new species, Spirocerca vulpis, from red foxes (Vulpes vulpes). However, in Southeast Asia, research on Spirocerca spp. is scarce. Therefore, the aim of this study is to explore Spirocerca infection in domestic dogs in Vietnam and to identify the Spirocerca species by analyzing their morphometric and molecular data. We found Spirocerca spp. specimens in 51 (17.7%) out of 287 dogs examined with the intensity of infection ranging from one to 29 nematodes per dog. These nematodes were morphologically and molecularly identified as S. lupi. For morphology, the presence/absence of teeth, the ratio of glandular to muscular esophagus lengths, and the position of the vulva opening of S. lupi and S. vulpis varied between reports, suggesting caution in identification of Spirocerca species based exclusively on morphological characteristics. The molecular analysis based on a partial cox1 sequence revealed that S. lupi from Vietnam is genetically close to those from India and China, but far different from those of Israel, South Africa, Peru and Hungary. Given high genetic and morphological variations, more extensive surveys on Spirocerca spp. from various mammalian hosts at a greater scale are necessary to elucidate the divergence of this nematode.


Assuntos
Doenças do Cão/epidemiologia , Infecções por Spirurida/veterinária , Thelazioidea/isolamento & purificação , Animais , Doenças do Cão/parasitologia , Cães , Complexo IV da Cadeia de Transporte de Elétrons/análise , Feminino , Proteínas de Helminto/análise , Masculino , Microscopia Eletrônica de Varredura/veterinária , Filogenia , Prevalência , Infecções por Spirurida/epidemiologia , Infecções por Spirurida/parasitologia , Thelazioidea/anatomia & histologia , Thelazioidea/genética , Thelazioidea/ultraestrutura , Vietnã/epidemiologia
6.
Comp Immunol Microbiol Infect Dis ; 77: 101671, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34049036

RESUMO

Dung beetles as detritivores insects, naturally use feces of vertebrates as foods and reproduction beds. This leads to frequent contacts between dung beetles and parasitic helminths. The current study was carried out to assess infections of dung beetles with larval stages of helminths in rural areas of Taleqan County, Alborz Province, Iran. A total number of 200 dung beetles were collected randomly in June 2017 from the highlands of Taleqan County. Beetles were dissected in normal saline and carefully studied using a stereomicroscope. Morphological characteristics of the recovered larvae were drawn using a camera lucida equipped microscope at 400× magnification. Then, genomic DNAs of the recovered larvae extracted and PCR amplifications of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene were carried out and the amplicons were sequenced. All collected dung beetles identified as Scarabaeus armeniacus from the Scarabaeidae family (55.5 % were male and 44.5 % female). Three females of the beetles have been found to be naturally infected with the third stage larvae of Spirocerca lupi. The average length and width of the larvae were 2.95 (2.81-3.15; CI 95 %) and 0.12 (0.1-0.15; CI 95 %) mm, respectively. The phylogenetic analysis showed that S. lupi belonged to a clade within the Spirocercidae family. In the current study, S. armeniacus introduced as a potential biological vector for transmission of S. lupi to vertebrates in the region. To the best of the authors' knowledge, this is the first report on the larval stages of S. lupi in S. armeniacus.


Assuntos
Besouros , Infecções por Spirurida , Thelazioidea , Animais , Fezes , Feminino , Irã (Geográfico) , Larva , Masculino , Filogenia , Infecções por Spirurida/veterinária
7.
Vet Parasitol Reg Stud Reports ; 23: 100510, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33678365

RESUMO

Spirocerca lupi is the etiologic agent of spirocercosis in canids from the tropical and subtropical regions of the world. A 1-year-old dog was presented with weight loss and diarrhea. Upon examination, thickened limbs, a mass in the lung's right middle lobe and an esophageal mass were found. The pulmonary mass aspirate revealed S. lupi eggs surrounded by a purulent infiltrate. Limb bone biopsies showed irregular mineralization and cartilaginous metaplasia. Treatment with doramectin resolved the initial clinical signs. However, regurgitation was reported 5 months later. Therefore, the dog received additional doramectin and later vomited a worm morphologically consistent with a S. lupi adult. Herein we report the esophageal migration of S. lupi with egg deposition to the lung parenchyma, accompanied by secondary hypertrophic osteopathy. This report highlights the presence of S. lupi in Costa Rica and the importance of including this parasite as a differential diagnosis when compatible signs are identified.


Assuntos
Doenças do Cão , Infecções por Spirurida , Thelazioidea , Animais , Costa Rica , Doenças do Cão/diagnóstico , Doenças do Cão/parasitologia , Cães/parasitologia , Pulmão , Infecções por Spirurida/diagnóstico , Infecções por Spirurida/veterinária
8.
J Parasitol ; 107(1): 132-137, 2021 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-33647985

RESUMO

The Northern bobwhite quail (Colinus virginianus) is a popular game bird that has been experiencing a well-documented decline throughout Texas since the 1960s. While much of this decline has been attributed to habitat loss and fragmentation, recent studies have identified other factors that may also contribute to decreasing quail populations. Parasites, in particular, have become increasingly recognized as possible stressors of quail, and some species, particularly the eyeworm (Oxyspirura petrowi) and cecal worm (Aulonocephalus pennula) are highly prevalent in Texas quails. Eyeworm infection has also been documented in some passerines, suggesting helminth infection may be shared between bird species. However, the lack of comprehensive helminth surveys has rendered the extent of shared infection between quail and passerines in the ecoregion unclear. Thus, helminth surveys were conducted on bobwhite, scaled quail (Callipepla squamata), Northern mockingbirds (Mimus polyglottos), curve-billed thrashers (Toxistoma curvirostre), and Northern cardinals (Cardinalis cardinalis) to contribute data to existing parasitological gaps for birds in the Rolling Plains ecoregion of Texas. Birds were trapped across 3 counties in the Texas Rolling Plains from March to October 2019. Necropsies were conducted on 54 individuals (36 quail and 18 passerines), and extracted helminths were microscopically identified. Nematode, cestode, and acanthocephalan helminths representing at least 10 helminth species were found. Specifically, A. pennula and O. petrowi had the highest prevalence, and O. petrowi was documented in all of the study species. This research adds to the body of knowledge regarding parasitic infections in quail and passerines of the Rolling Plains ecoregion and highlights the potential consequences of shared infection of eyeworms among these bird species.


Assuntos
Doenças das Aves/parasitologia , Cromadoria/isolamento & purificação , Colinus/parasitologia , Helmintíase Animal/parasitologia , Passeriformes/parasitologia , Thelazioidea/isolamento & purificação , Animais , Doenças das Aves/epidemiologia , Cromadoria/classificação , Infecções Oculares Parasitárias/epidemiologia , Infecções Oculares Parasitárias/parasitologia , Infecções Oculares Parasitárias/veterinária , Helmintíase Animal/epidemiologia , Prevalência , Infecções por Spirurida/epidemiologia , Infecções por Spirurida/parasitologia , Infecções por Spirurida/veterinária , Texas/epidemiologia , Thelazioidea/classificação
9.
Parasitol Int ; 83: 102333, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33731302

RESUMO

Cases of gnathostomiasis, an infection caused by consuming infected seafood, have been reported in Australia. However, doubt exists over the validity of these diagnoses as there are no reports of Gnathostoma spp. in Australian teleost fish. Also, the diagnoses in human cases were based on a serological test developed in Thailand. The specificity and sensitivity of this test in non-endemic areas are uncertain. Interestingly, parasites belonging to the genus Echinocephalus, which morphologically are very similar to Gnathostomum, are commonly found in Australian fish and shellfish and can potentially infect humans. The aim of this study was to determine the occurrence of these zoonotic nematodes within commercial fish and to characterise nematode larvae in order to provide insights into the specific identity of the potential causative agents of gnathostomiasis in Australia. Six edible fish species (n = 163) were examined. Gnathostomid-type larvae were found only in Acanthopagrus australis and Rhabdosargus sarba. Detailed examination and sequence data suggested parasite larvae belonged to the genus Echinocephalus. Further investigation of the occurrence of zoonotic nematodes within marine environments and observation of their spatial and temporal patterns will help raise awareness of the significance of this food safety issue within global fishing industries and health sectors. The accurate identification of zoonotic nematodes is a key component of disease surveillance and control. This information can also be used to develop specific and sensitive diagnostic test.


Assuntos
Doenças dos Peixes/parasitologia , Parasitologia de Alimentos/estatística & dados numéricos , Infecções por Spirurida/veterinária , Thelazioidea/fisiologia , Animais , Austrália , Peixes , Larva/crescimento & desenvolvimento , Larva/fisiologia , Infecções por Spirurida/parasitologia , Thelazioidea/crescimento & desenvolvimento
10.
Artigo em Alemão | MEDLINE | ID: mdl-33588466

RESUMO

Thelazia callipaeda is a vector-borne nematode transmitted by Phortica spp. (fruit flies) and one of the causes of mild to severe conjunctivitis and keratitis in dogs, cats, rabbits and humans. It has been formerly known as the oriental eye worm based on its geographic occurrence. By now, it has been shown to be endemic in several southern and eastern European countries as well as extending its geographic distribution further throughout Europe. In the present case report, T. callipaeda infection was diagnosed in a female dog from Germany. The dog was referred by a local veterinarian due to a treatment-resistant conjunctivitis. A comprehensive ophthalmologic examination revealed 3 adult eye worms in the conjunctival sac as well as on the bulbar side of the nictitating membrane of the left eye. These were identified by morphological features and molecular techniques as T. callipaeda and represented the primary cause of the dog's unilateral blepharospasm, hyperemic conjunctiva and epiphora. Treatment consisted of manual collection of the adult worms and the administration of moxidectin/imidacloprid as spot on (Advocate®, Bayer). All clinical signs resolved within one week after treatment. In Germany, ocular thelaziosis still represents a rare disease. Usually, it is diagnosed in cats and dogs either imported from abroad or accompanying the owners on holiday travels to endemic countries. The dog presented in this case report was born in Germany. Except for a one-week stay in the Netherlands 11 months before the symptoms began, it had never traveled abroad. Considering the prepatency of T. callipaeda, an autochthonous transmission in this case is highly probable.


Assuntos
Doenças do Cão/parasitologia , Infecções Oculares Parasitárias/veterinária , Infecções por Spirurida/veterinária , Thelazioidea/isolamento & purificação , Animais , Antinematódeos/uso terapêutico , Blefarospasmo/parasitologia , Blefarospasmo/veterinária , Transmissão de Doença Infecciosa/veterinária , Doenças do Cão/terapia , Doenças do Cão/transmissão , Cães , Drosophilidae/parasitologia , Infecções Oculares Parasitárias/parasitologia , Infecções Oculares Parasitárias/terapia , Infecções Oculares Parasitárias/transmissão , Feminino , Alemanha , Hiperemia/parasitologia , Hiperemia/veterinária , Insetos Vetores/parasitologia , Inseticidas/uso terapêutico , Aparelho Lacrimal/parasitologia , Doenças do Aparelho Lacrimal/parasitologia , Doenças do Aparelho Lacrimal/veterinária , Macrolídeos/uso terapêutico , Neonicotinoides/uso terapêutico , Membrana Nictitante/parasitologia , Nitrocompostos/uso terapêutico , Infecções por Spirurida/parasitologia , Infecções por Spirurida/terapia , Infecções por Spirurida/transmissão , Thelazioidea/classificação
11.
Parasit Vectors ; 14(1): 13, 2021 Jan 06.
Artigo em Inglês | MEDLINE | ID: mdl-33407836

RESUMO

BACKGROUND: Thelazia callipaeda is a zoonotic parasitic nematode of the family Thelaziidae, with Phortica okadai as its intermediate host and only confirmed vector in China. China has the largest number of human cases of thelaziosis in the world. It is generally believed that infected domestic animals (dogs and cats) are the most important reservoir hosts of T. callipaeda, and thus pose a direct threat to humans. At present, there is little research or attention focused on the role of wildlife in the transmission cycle of thelaziosis in nature reserves. METHODS: We selected locations in four national nature reserves across China to monitor P. okadai and wildlife. We used a fly-trap method to monitor P. okadai density. Morphological analysis of the parasites collected from the conjunctival sac of the infected wildlife was undertaken as the first step in species identification, and polymerase chain reaction (PCR) was used for species confirmation. RESULTS: In 2019, the density of P. okadai in Foping National Nature Reserve in China increased sharply, and infected P. okadai were newly found in the reserve. Giant panda, wild boar, leopard cat, and black bear were found to be newly infected with T. callipaeda (one individual of each species). A total of four worms were collected, one from each species of wildlife. The four worms were identified as T. callipaeda by their morphological characteristics; species identification was confirmed by PCR amplification. CONCLUSIONS: To the best of our knowledge, this is the first report of T. callipaeda infection in P. okadai as well as in a variety of wildlife, including giant panda, in nature reserves in China. These results indicate that there is a transmission cycle of T. callipaeda among wildlife in these nature reserves. The increasing number of case reports of thelaziosis in wildlife suggest a likely risk of T. callipaeda infection for the inhabitants of villages situated around nature reserves.


Assuntos
Animais Selvagens/parasitologia , Drosophilidae/parasitologia , Thelazioidea/isolamento & purificação , Animais , Doenças do Gato/parasitologia , Doenças do Gato/transmissão , Gatos , China/epidemiologia , Reservatórios de Doenças/veterinária , Doenças do Cão/parasitologia , Doenças do Cão/transmissão , Cães , Infecções Oculares Parasitárias/transmissão , Humanos , Insetos Vetores/parasitologia , Infecções por Nematoides/transmissão , Sus scrofa/parasitologia , Ursidae/parasitologia , Doenças Transmitidas por Vetores/transmissão , Zoonoses/parasitologia , Zoonoses/transmissão
12.
Int J Parasitol ; 51(1): 73-81, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33091413

RESUMO

This study examines the therapeutic and year-round prophylactic efficacy of different formulations used in dogs in three Spanish areas where canine thelaziosis is endemic. The study was conducted as a Good Clinical Practice, multicentre, randomised field study in privately owned outdoor dogs naturally infected with Thelazia callipaeda. The active pharmaceutical ingredients tested were: an oral formulation of milbemycin oxime 12.5 mg combined with praziquantel 125 mg (A), a subcutaneous sustained-release formulation of moxidectin 10 g (B), a moxidectin 2.5% weight/volume (w/v) spot-on formulation combined with imidacloprid 10% w/v (C), and an eye drop formulation (6 µg) of ivermectin 10 mg/ml diluted 10% in propylene glycol (D). Infected dogs were randomly allocated to treatment Groups A, B, C and D. Dogs testing negative for T. callipaeda inspection in two visits (Day 7/Day 14 and D30) were enrolled in the prophylaxis trial and reallocated to the corresponding study group (A, B, C or D). Treatment efficacy ranged from 70.4% recorded in Group A 1 week after treatment, to 100% recorded in Group C on Day 30 and in Group B on Day 60. Treatment was more efficacious in Group D (85.7% 1 week after treatment) than A, but was never 100% efficacious as in Groups B and C. Year-round prophylactic efficacy was 83.3% in Group A, 100% in Group B, 93.5% in Group C and 87.5% in Group D. In conclusion, products containing moxidectin were highly efficacious both in treating and preventing canine thelaziosis. Milbemycin also emerged as a good option. However, the off-label use of topical or subcutaneous ivermectin should be avoided due to possible adverse reactions such as pruritus, irritation or redness. In endemic areas, monthly prophylaxis to limit the spread of T. callipaeda to new areas across Europe and reduce zoonotic risks is essential.


Assuntos
Doenças do Cão , Infecções por Spirurida , Thelazioidea , Animais , Doenças do Cão/tratamento farmacológico , Doenças do Cão/prevenção & controle , Cães , Macrolídeos/uso terapêutico , Praziquantel , Espanha , Infecções por Spirurida/tratamento farmacológico , Infecções por Spirurida/prevenção & controle , Infecções por Spirurida/veterinária
13.
Parasitol Int ; 80: 102243, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33186725

RESUMO

A variety of helminths have been found in domestic chickens in Bangladesh, but little is known about their gene sequences. Here, parasitic nematodes and trematodes were collected from the eyes of domestic chickens and analyzed for their morphological and morphometric characteristics, and characterized molecularly. The helminths were identified as Oxyspirura mansoni and Philophthalmus gralli. The ITS1 and ITS2 sequences of O. mansoni were 532 bp and 306 bp in length, respectively, and showed low identity (50.7-62.7%) with those of O. petrowi and O. conjunctivalis. Furthermore, the O. mansoni CO1 sequences (393 bp) showed five haplotypes (97.5-99.5% similarity) that formed a monophyletic clade. With respect to P. gralli, the ITS1 (452 bp) and ITS2 (736 bp) sequences showed 100% similarity with the reference sequences in GenBank. Both the ND1 and CO1 phylograms showed that P. gralli from Bangladesh, Costa Rica and Peru form a monophyletic clade, distinct from the clades of P. lucipetus and P. lacrymosus. Our data show that, Philophthalmus gralli isolates from Bangladesh, Costa Rica and Peru are genetically close to each other.


Assuntos
Galinhas , Marcadores Genéticos , Proteínas de Helminto/análise , Doenças das Aves Domésticas/parasitologia , Thelazioidea/genética , Trematódeos/genética , Animais , Bangladesh , Complexo IV da Cadeia de Transporte de Elétrons/análise , Oftalmopatias/parasitologia , Feminino , Masculino , RNA de Helmintos/análise , Infecções por Spirurida/parasitologia , Thelazioidea/classificação , Thelazioidea/enzimologia , Trematódeos/classificação , Infecções por Trematódeos/parasitologia
14.
Parasitol Int ; 80: 102183, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32891881

RESUMO

Bovine thelaziosis can be caused by Thelazia rhodesi Desmarest 1828, Thelazia gulosa Railliet & Henry 1910 and Thelazia skrjabini Erschow 1928 which are known to be transmitted by species of Muscidae. Therapeutic measures in cattle include mechanical removal of the adult parasites, followed by irrigation of the conjunctival sac with different solutions such as levamisole (1%) or administration of ivermectin (0.2 mg/kg SC), doramectin (0.2 mg/kg SC or pour-on) both with high efficacy, however, the use of such macrocyclic lactones can be problematic in lactating cattle. Nematodes harboured in the eyes of some cattle from Romania were morphologically identified as Thelazia rhodesi and the PCR analysis confirmed the diagnosis with a 98.0% nucleotide similarity for ITS1 sequence, with other sequences available in GenBank. The present paper reports the presence of T. rhodesi in cattle from a dairy farm in Romania and the recovery after treatment with eprinomectin. To the best of our knowledge this is the first report on the efficacy of eprinomectin against Thelazia spp. and the first molecular confirmation of T. rhodesi in Romania.


Assuntos
Anti-Helmínticos/uso terapêutico , Doenças dos Bovinos/prevenção & controle , Ivermectina/análogos & derivados , Infecções por Spirurida/veterinária , Thelazioidea/fisiologia , Animais , Bovinos , Doenças dos Bovinos/parasitologia , Indústria de Laticínios , Fazendas , Feminino , Ivermectina/uso terapêutico , Masculino , Romênia , Infecções por Spirurida/parasitologia , Infecções por Spirurida/prevenção & controle , Thelazioidea/efeitos dos fármacos
15.
Eur J Ophthalmol ; 31(6): NP45-NP47, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32586115

RESUMO

INTRODUCTION: We report a local human case of Thelazia callipaeda eye infection in a 49-year-old lady with history of fly contact in Hong Kong. CASE DESCRIPTION: A 49-year-old lady presented with right eye foreign body sensation for one month. She recalled a fly being stuck onto her right upper eyelashes with mascara when she went hiking in a forest trail in Hong Kong. On assessment there were a lot of giant papillae on palpebral conjunctiva. Three living worms crawling on conjunctiva were discovered and removed in total. The worms were identified as Thelazia callipaeda by morphology and molecular sequencing. After removal, her symptoms resolved completely. CONCLUSION: Human thelaziasis is probably under-reported in many countries. The presence of giant papillary conjunctivitis in non-contact lens wearers should alert clinicians to the possibility of thelaziasis in patients with compatible exposure history in endemic regions. Ophthalmologists should increase their awareness towards this uncommon disease and should not wrongly attributed the symptoms to allergic conjunctivitis.


Assuntos
Conjuntivite Alérgica , Conjuntivite , Infecções Oculares Parasitárias , Infecções por Spirurida , Thelazioidea , Animais , Túnica Conjuntiva , Conjuntivite/diagnóstico , Infecções Oculares Parasitárias/diagnóstico , Feminino , Humanos , Pessoa de Meia-Idade , Infecções por Spirurida/diagnóstico
17.
Vet Rec ; 187(9): 348-349, 2020 10 31.
Artigo em Inglês | MEDLINE | ID: mdl-33127780
18.
Parasitol Res ; 119(12): 4277-4280, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33048206

RESUMO

A 12-year old Elo dog was presented with recurring symptoms of conjunctivitis in November 2019. A single whitish nematode was found upon inspection of the eye and identified as a Thelazia callipaeda male. The morphological identification of the eye worm was supported by analysis of a partial cytochrome c oxidase I (cox1) gene sequence. The dog lived in Lower Saxony, northwestern Germany, and had not visited regions known to be endemic for T. callipaeda. This suggests that a local transmission cycle of this zoonotic nematode may exist in Germany.


Assuntos
Doenças do Cão/parasitologia , Infecções por Spirurida/veterinária , Thelazioidea/isolamento & purificação , Animais , Doenças do Cão/transmissão , Cães , Complexo IV da Cadeia de Transporte de Elétrons/genética , Olho/parasitologia , Feminino , Alemanha , Proteínas de Helminto/genética , Masculino , Infecções por Spirurida/parasitologia , Infecções por Spirurida/transmissão , Thelazioidea/classificação , Thelazioidea/citologia , Thelazioidea/genética
19.
Parasite ; 27: 52, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32996882

RESUMO

Cases of thelaziosis by Thelazia callipaeda have been increasing considerably in Europe throughout the 21st century, with recent emphasis on Eastern Europe. A systematic review was conducted using defined search terms across three major databases and, additionally, with the examination of the references of the 56 articles selected. Available information about epidemiological and clinical features of all cases of thelaziosis by T. callipaeda in companion animals, wildlife and humans was extracted, evaluated and subjected to qualitative and quantitative analysis. In all cross-sectional studies about dogs, cats and red foxes, males were more frequently infected than females (dogs: p = 0.0365; cats: p = 0.0164; red foxes: p = 0.0082). Adult dogs seem to be more prone to infection (p < 0.0001), as well as large-sized dogs (p < 0.0001), and companion animals that live exclusively outdoors (p < 0.0001). Dogs and red foxes involved in these cross-sectional studies harboured significantly more female than male nematodes (p < 0.0001). Thelaziosis by T. callipaeda is far from controlled in Europe. Only through updated epidemiological data, knowledge improvement and awareness can correct diagnosis and appropriate treatment and prevention be ensured to tackle this zoonosis.


Assuntos
Gatos , Cães , Raposas , Infecções por Spirurida , Thelazioidea , Animais , Gatos/parasitologia , Estudos Transversais , Cães/parasitologia , Europa (Continente)/epidemiologia , Feminino , Raposas/parasitologia , Humanos , Masculino , Doenças Parasitárias em Animais/epidemiologia , Infecções por Spirurida/epidemiologia , Infecções por Spirurida/prevenção & controle
20.
Parasitol Res ; 119(10): 3531-3534, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32827103

RESUMO

In this study, we describe a rare human case with corneal ulcer caused by thelaziosis in a 69-year-old man in Southwest China. A male nematode was discovered and removed from the patient's right eye with a long spicule and further identified by sequencing mitochondrial cox1 gene. The ophthalmologic and molecular biological evidence demonstrates the corneal ulcer caused by T. callipaeda infection, which is mainly distributed in Asian and European countries. Most T. callipaeda infections are emerged in the conjunctiva, leading to conjunctivitis. To the best knowledge of the authors, corneal ulcers caused by T. callipaeda have not been reported yet.


Assuntos
Úlcera da Córnea/parasitologia , Infecções por Spirurida/parasitologia , Thelazioidea/isolamento & purificação , Idoso , Animais , China , Túnica Conjuntiva/parasitologia , Genes de Helmintos/genética , Genes Mitocondriais/genética , Humanos , Masculino , Thelazioidea/citologia , Thelazioidea/genética
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