Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 11.828
Filtrar
2.
Sci Rep ; 13(1): 514, 2023 Jan 10.
Artigo em Inglês | MEDLINE | ID: mdl-36627333

RESUMO

Gastric Function has been successfully estimated by gastric electrical impedance tomography (gEIT) Suit with dual-step fuzzy clustering. The gEIT Suit which are made of elastic cloth with dual-planar electrodes and compact data acquisition (DAQ) system measures gastric impedance Z to visualize the gastric conductivity distribution σ. The dual-step fuzzy clustering extracts the clustered gastric conductivity distribution kσ, which accurately estimates the gastric function. The gEIT Suit with dual-step fuzzy clustering are applied to eight healthy persons during liquid meal consumption to estimate the gastric function under gastric accommodation phase of 200, 400 and 600 mL based on the gastric emptying phase. As the results, the gEIT Suit successfully estimate the gastric function. By the measured impedance Z, the subjects have a mean temporal impedance [Formula: see text]= - 9.27 [Ohm] and p-value of that [Formula: see text] p(Z) = 0.0013[-]as the t-test result. In the case of gastric conductivity distribution σ, the subjects have a value of spatial mean conductivity distribution ⟨σ⟩ = 0.23[-] and p-value of that ⟨σ⟩ p(σ) = 0.0140[-]. Lastly, in the case gastric volume V, subjects have a gastric volume V = 12.44 [%] and p-value p(V) = 0.0664[-].


Assuntos
Esvaziamento Gástrico , Estômago , Humanos , Impedância Elétrica , Estômago/diagnóstico por imagem , Condutividade Elétrica , Tomografia Computadorizada por Raios X , Tomografia
3.
Eur J Radiol ; 159: 110668, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36608599

RESUMO

PURPOSE: To investigate the clinical value of measuring pancreatic fat fraction using dual-energy computed tomography (DECT) in association with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: This retrospective study included patients who underwent abdominal DECT between September 2021 and July 2022. The fat fractions in the head, body, and tail of the pancreas were calculated using fat maps generated from unenhanced DECT images, and CT values were measured at the same locations. The intraclass correlation coefficient (ICC) was used to analyze the reproducibility of measurements from two observers. Diagnostic performance was assessed using receiver operating characteristic curves. RESULTS: Seventy-eight patients, including 45 T2DM patients and 33 controls, were enrolled. The fat fractions of the pancreas were significantly higher in the T2DM group than in the control group (pancreatic head: 8.4 ± 6.3 % vs 5.1 ± 3.9 %; pancreatic body: 4.8 ± 4.0 % vs 2.7 ± 3.9 %; and pancreatic tail: 5.3 ± 3.2 % vs 2.7 ± 2.9 %, all p < 0.05). And the CT values of the pancreas were significantly lower in the T2DM group than in the control group (pancreatic head: 41.1 ± 8.5 HU vs 45.7 ± 4.6 HU; pancreatic body: 44.4 ± 5.0 HU vs 47.4 ± 3.7 HU; and pancreatic tail: 44.5 ± 5.0 HU vs 47.6 ± 3.2 HU, all p < 0.05). The fat fraction of the pancreatic tail was the best indicator for distinguishing T2DM patients from the controls (area under the curve: 0.716 (95 % CI: 0.601, 0.832), sensitivity: 64.4 % (95 % CI: 48.7 %, 77.7 %), and specificity: 78.8 % (95 % CI: 60.6 %, 90.4 %)). CONCLUSION: The DECT fat fractions of the pancreas could be a valuable additional parameter in the detection of T2DM.


Assuntos
Diabetes Mellitus Tipo 2 , Humanos , Diabetes Mellitus Tipo 2/diagnóstico por imagem , Estudos Retrospectivos , Reprodutibilidade dos Testes , Pâncreas/diagnóstico por imagem , Tomografia
4.
J Nanobiotechnology ; 21(1): 21, 2023 Jan 19.
Artigo em Inglês | MEDLINE | ID: mdl-36658555

RESUMO

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic nonspecific disease with unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a certain extent of effects in terms of inflammation alleviation. Still, the final pathological outcome of intestinal fibrosis has not been effectively improved yet. RESULTS: In this study, dextran-coated cerium oxide (D-CeO2) nanozyme with superoxide dismutase (SOD) and catalase (CAT) activities was synthesized by chemical precipitation. Our results showed that D-CeO2 could efficiently scavenge reactive oxide species (ROS) as well as downregulate the pro-inflammatory cytokines (IL-1ß, IL-6, TNF-α, and iNOS) to protect cells from H2O2-induced oxidative damage. Moreover, D-CeO2 could suppress the expression of fibrosis-related gene levels, such as α-SMA, and Collagen 1/3, demonstrating the anti-fibrotic effect. In both TBNS- and DSS-induced colitis models, oral administration of D-CeO2 in chitosan/alginate hydrogel alleviated intestinal inflammation, reduced colonic damage by scavenging ROS, and decreased inflammatory factor levels. Notably, our findings also suggested that D-CeO2 reduced fibrosis-related cytokine levels, predicting a contribution to alleviating colonic fibrosis. Meanwhile, D-CeO2 could also be employed as a CT contrast agent for noninvasive gastrointestinal tract (GIT) imaging. CONCLUSION: We introduced cerium oxide nanozyme as a novel therapeutic approach with computed tomography (CT)-guided anti-inflammatory and anti-fibrotic therapy for the management of IBD. Collectively, without appreciable systemic toxicity, D-CeO2 held the promise of integrated applications for diagnosis and therapy, pioneering the exploration of nanozymes with ROS scavenging capacity in the anti-fibrotic treatment of IBD.


Assuntos
Cério , Doenças Inflamatórias Intestinais , Humanos , Anti-Inflamatórios/farmacologia , Anti-Inflamatórios/uso terapêutico , Antioxidantes/farmacologia , Cério/farmacologia , Citocinas/metabolismo , Fibrose , Peróxido de Hidrogênio , Inflamação , Doenças Inflamatórias Intestinais/diagnóstico por imagem , Doenças Inflamatórias Intestinais/tratamento farmacológico , Espécies Reativas de Oxigênio/metabolismo , Tomografia , Tomografia Computadorizada por Raios X
5.
Clin J Pain ; 39(2): 68-75, 2023 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-36650602

RESUMO

OBJECT: To estimate the contrast dispersion short-term clinical efficacy and safety of ultrasound (US)-guided transforaminal steroid injection (TFSI) compared with computed tomography (CT) guidance for the treatment of cervical radicular pain. METHOD: A total of 430 patients with cervical radicular pain from cervical herniated disk or cervical spondylosis were recruited in the randomized, single-blind, controlled, noninferiority trial. The patients were randomly assigned to receive either the US-guided or CT-guided TFSI for 1 affected cervical nerve. The dispersion pattern of contrast was monitored at the time of TFSI in both groups, using CT. Patients were assessed for pain intensity by numeric rating scale (NrS) and functional disability by Neck Disability Index (NDI) at baseline, 1 and 3 months after the intervention. Complications were also recorded. RESULTS: The satisfactory rate of contrast distribution was respectively 92.1% in US group and 95.8% in CT group. Pain reduction and functional improvement were showed in both groups during follow-up. Statistical difference was not observed in the decrease in NRS pain scores and NDI scores between 2 groups with F =1.050, P =0.306 at 1 month and F =0.103, P =0.749 at 3 months after intervention. No permanent and severe complications were observed. CONCLUSIONS: This study demonstrated that US provided a noninferior injectate spread pattern and similar improvement of radicular pain and functional status when compared with CT-guided TFSI. US may be advantageous during this procedure because it allows visualization of critical vessels and avoids radiation exposure.


Assuntos
Cervicalgia , Radiculopatia , Humanos , Método Simples-Cego , Cervicalgia/diagnóstico por imagem , Cervicalgia/tratamento farmacológico , Cervicalgia/etiologia , Resultado do Tratamento , Vértebras Cervicais/diagnóstico por imagem , Ultrassonografia de Intervenção/métodos , Fluoroscopia/métodos , Tomografia Computadorizada por Raios X/métodos , Esteroides/uso terapêutico , Tomografia , Radiculopatia/diagnóstico por imagem , Radiculopatia/tratamento farmacológico , Injeções Epidurais/métodos
7.
J Comput Assist Tomogr ; 47(1): 3-8, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36668978

RESUMO

OBJECTIVE: To quantify the association between computed tomography abdomen and pelvis with contrast (CTAP) findings and chest radiograph (CXR) severity score, and the incremental effect of incorporating CTAP findings into predictive models of COVID-19 mortality. METHODS: This retrospective study was performed at a large quaternary care medical center. All adult patients who presented to our institution between March and June 2020 with the diagnosis of COVID-19 and had a CXR up to 48 hours before a CTAP were included. Primary outcomes were the severity of lung disease before CTAP and mortality within 14 and 30 days. Logistic regression models were constructed to quantify the association between CXR score and CTAP findings. Penalized logistic regression models and random forests were constructed to identify key predictors (demographics, CTAP findings, and CXR score) of mortality. The discriminatory performance of these models, with and without CTAP findings, was summarized using area under the characteristic (AUC) curves. RESULTS: One hundred ninety-five patients (median age, 63 years; 119 men) were included. The odds of having CTAP findings was 3.89 times greater when a CXR score was classified as severe compared with mild (P = 0.002). When CTAP findings were included in the feature set, the AUCs for 14-day mortality were 0.67 (penalized logistic regression) and 0.71 (random forests). Similar values for 30-day mortality were 0.76 and 0.75. When CTAP findings were omitted, all AUC values were attenuated. CONCLUSIONS: The CTAP findings were associated with more severe CXR score and may serve as predictors of COVID-19 mortality.


Assuntos
COVID-19 , Adulto , Masculino , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Abdome , Tomografia , Radiografia Torácica
9.
Opt Lett ; 48(2): 199-202, 2023 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-36638417

RESUMO

The imaging fidelity of mesoscopic fluorescence molecular tomography (MFMT) in reflective geometry suffers from spatial nonuniformity of measurement sensitivity and ill-posed reconstruction. In this study, we present a spatially adaptive split Bregman network (SSB-Net) to simultaneously overcome the spatial nonuniformity of measurement sensitivity and promote reconstruction sparsity. The SSB-Net is derived by unfolding the split Bregman algorithm. In each layer of the SSB-Net, residual block and 3D convolution neural networks (3D-CNNs) can adaptively learn spatially nonuniform error compensation, the spatially dependent proximal operator, and sparsity transformation. Simulations and experiments show that the proposed SSB-Net enables high-fidelity MFMT reconstruction of multifluorophores at different positions within a depth of a few millimeters. Our method paves the way for a practical reflection-mode diffuse optical imaging technique.


Assuntos
Tomografia Óptica , Tomografia Óptica/métodos , Algoritmos , Redes Neurais de Computação , Processamento de Imagem Assistida por Computador/métodos , Tomografia , Imagens de Fantasmas
10.
Crit Care ; 27(1): 21, 2023 01 17.
Artigo em Inglês | MEDLINE | ID: mdl-36650593

RESUMO

BACKGROUND: In patients with acute respiratory distress syndrome undergoing mechanical ventilation, positive end-expiratory pressure (PEEP) can lead to recruitment or overdistension. Current strategies utilized for PEEP titration do not permit the distinction. Electric impedance tomography (EIT) detects and quantifies the presence of both collapse and overdistension. We investigated whether using EIT-guided PEEP titration leads to decreased mechanical power compared to high-PEEP/FiO2 tables. METHODS: A single-center, randomized crossover pilot trial comparing EIT-guided PEEP selection versus PEEP selection using the High-PEEP/FiO2 table in patients with moderate-severe acute respiratory distress syndrome. The primary outcome was the change in mechanical power after each PEEP selection strategy. Secondary outcomes included changes in the 4 × driving pressure + respiratory rate (4 ΔP, + RR index) index, driving pressure, plateau pressure, PaO2/FiO2 ratio, and static compliance. RESULTS: EIT was consistently associated with a decrease in mechanical power compared to PEEP/FiO2 tables (mean difference - 4.36 J/min, 95% CI - 6.7, - 1.95, p = 0.002) and led to lower values in the 4ΔP + RR index (- 11.42 J/min, 95% CI - 19.01, - 3.82, p = 0.007) mainly driven by a decrease in the elastic-dynamic power (- 1.61 J/min, - 2.99, - 0.22, p = 0.027). The elastic-static and resistive powers were unchanged. Similarly, EIT led to a statistically significant change in set PEEP (- 2 cmH2O, p = 0.046), driving pressure, (- 2.92 cmH2O, p = 0.003), peak pressure (- 6.25 cmH2O, p = 0.003), plateau pressure (- 4.53 cmH2O, p = 0.006), and static respiratory system compliance (+ 7.93 ml/cmH2O, p = 0.008). CONCLUSIONS: In patients with moderate-severe acute respiratory distress syndrome, EIT-guided PEEP titration reduces mechanical power mainly through a reduction in elastic-dynamic power. Trial registration This trial was prospectively registered on Clinicaltrials.gov (NCT03793842) on January 4th, 2019.


Assuntos
Síndrome do Desconforto Respiratório , Humanos , Impedância Elétrica , Projetos Piloto , Síndrome do Desconforto Respiratório/terapia , Respiração com Pressão Positiva/métodos , Tomografia/métodos
12.
Ear Nose Throat J ; 102(1): NP35-NP39, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33433233

RESUMO

OBJECTIVES: Peritonsillar abscess (PTA) is the most common deep neck space infection and a frequent cause for otolaryngology consultation. Patients often undergo computed tomography (CT) scan for confirmation in addition to physical examination. Our aims were to determine whether patients unnecessarily undergo CT scans in the emergency department (ED) when presenting with sore throat and identify physical examination characteristics that predict PTA. METHODS: The electronic medical records of all patients (>18 years) presenting to an ED between June 2014 and June 2015 with a primary diagnosis of acute pharyngitis, acute tonsillitis, or PTA were reviewed for presenting symptoms and diagnostic imaging use. RESULTS: Four hundred eight patients met inclusion criteria; 21 were diagnosed with PTA, including 13 based on history and physical alone. A total of 21 CT scans were ordered, 11 (52.3%) of which did not demonstrate abscess. Soft palatal fullness, uvular deviation, drooling, and muffled voice were all significantly associated with increased CT usage (all P values <.02). Rising subjective pain scores were associated with increased use of CT imaging (P = .029). Multivariable analyses revealed that soft palatal fullness, uvular deviation, and drooling were all significant predictors of PTA (all P values <.001). CONCLUSIONS: Patients with severe symptoms of PTA, including uvular deviation, drooling, and soft palatal fullness, were most likely to undergo CT imaging. Given the high likelihood of PTA, patients presenting with these symptoms could forego CT imaging, reducing exposure to ionizing radiation.


Assuntos
Abscesso Peritonsilar , Humanos , Abscesso Peritonsilar/diagnóstico por imagem , Serviço Hospitalar de Emergência , Tomografia Computadorizada por Raios X , Tomografia
13.
Phys Med Biol ; 68(3)2023 Jan 20.
Artigo em Inglês | MEDLINE | ID: mdl-36584394

RESUMO

Objective.Magnetic particle imaging (MPI) is an emerging tomography imaging technique with high specificity and temporal-spatial resolution. MPI reconstruction based on the system matrix (SM) is an important research content in MPI. However, SM is usually obtained by measuring the response of an MPI scanner at all positions in the field of view. This process is very time-consuming, and the scanner will overheat in a long period of continuous operation, which is easy to generate thermal noise and affects MPI imaging performance.Approach.In this study, we propose a deep image prior-based method that prominently decreases the time of SM calibration. It is an unsupervised method that utilizes the neural network structure itself to recover a high-resolution SM from a downsampled SM without the need to train the network using a large amount of training data.Main results.Experiments on the Open MPI data show that the time of SM calibration can be greatly reduced with only slight degradation of image quality.Significance.This study provides a novel method for obtaining SM in MPI, which shows the potential to achieve SM recovery at a high downsampling rate. It is expected that this study will increase the practicability of MPI in biomedical applications and promote the development of MPI in the future.


Assuntos
Nanopartículas de Magnetita , Nanopartículas de Magnetita/química , Tomografia , Imagens de Fantasmas , Redes Neurais de Computação , Fenômenos Magnéticos
14.
Ultramicroscopy ; 245: 113669, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36566528

RESUMO

Given a limited radiation exposure to be distributed over a discrete number of tilted projections in tomography, the optimal collection of information depends on the tilt increment scheme. Relying on principles of sampling theory, several tilt increment schemes can be compared and quantified. Following reasoning of Saxton, a revised scheme is offered in which the tilt angle increments Δθn are proportional to 1/cosθn. The revised scheme is preferable according to matrix analysis and simulations of geometrical optics. For thin specimens, applying a cosine sampling grid similar to Hoppe's scheme can improve the results. A realistic case is examined by Dr. Probe simulation of a scanning transmission electron microscope (STEM) for an atomic model adapted from the Ferritin protein molecule. Optimal reconstruction methods that are tested include the direct algebraic method, iterative reconstruction, and a new deconvolution-based weighted back-projection, which resembles the correction filter technique in signal recovery from sub-sampled data. A non-linear correction may be accounted for by iteration of the simulation with an ad-hoc atomic model.


Assuntos
Processamento de Imagem Assistida por Computador , Tomografia , Processamento de Imagem Assistida por Computador/métodos , Tomografia/métodos , Tomografia Computadorizada por Raios X/métodos , Simulação por Computador , Algoritmos
15.
ASAIO J ; 69(2): e66-e72, 2023 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-36521051

RESUMO

Right ventricular (RV) function is an important marker of mortality in chronic left-sided heart failure. Right ventricular function is particularly important for patients receiving left ventricular assist devices as it is a predictor of postoperative RV failure. RV stroke work index (RVSWI), the area enclosed by a pressure-volume (PV) loop, is prognostic of RV failure. However, clinical RVSWI approximates RVSWI as the product of thermodilution-derived stroke volume and the pulmonary pressure gradient. This ignores the energetic contribution of regurgitant flow and does not allow for advanced energetic measures, such as pressure-volume area and efficiency. Estimating RVSWI from forward flow may underestimate the underlying RV function. We created single-beat PV loops by combining data from cine computed tomography (CT) and right heart catheterization in 44 heart failure patients, tested the approximations made by clinical RVSWI and found it to underestimate PV loop RVSWI, primarily due to regurgitant flow in tricuspid regurgitation. The ability of RVSWI to predict post-operative RV failure improved when the single-beat approach was used. Further, RV pressure-volume area and efficiency measures were obtained and show broad agreement with other functional measures. Future work is needed to investigate the utility of these PV metrics in a clinical setting.


Assuntos
Insuficiência Cardíaca , Disfunção Ventricular Direita , Humanos , Ventrículos do Coração/diagnóstico por imagem , Insuficiência Cardíaca/diagnóstico por imagem , Insuficiência Cardíaca/cirurgia , Cateterismo Cardíaco/métodos , Prognóstico , Tomografia , Volume Sistólico
16.
Acad Emerg Med ; 30(1): 16-22, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36478487

RESUMO

BACKGROUND: Delirium in older people is associated with significant morbidity and mortality and has life-threatening etiologies making prompt recognition essential. Computed tomography of the head (CT-head) may have a role in determining the cause of delirium; however, inpatient studies suggest it is overused. There is a paucity of emergency department (ED)-based research surrounding the use of CT-head in delirium. This study aims to describe the utility of CT-head in older patients presenting to the ED with symptoms of delirium. METHODS: We conducted a retrospective chart review of patients 65 years and older with symptoms of delirium who visited local EDs over a 3.5-year period (2016-2020). We compared patients who did and did not receive CT-head. Our primary objective was to determine the proportion of acute findings in patients who received CT-head. Our secondary objectives were to describe the proportions of patients who did and did not receive CT-head in terms of their demographics, presenting symptoms, disposition, and indications for and results of CT-head scans. Chi-square tests were utilized for comparisons. RESULTS: A total of 630 encounters were identified through database searching; 526 met inclusion criteria. Thirty-four were excluded for presenting directly to consultants, leaving 492 included encounters. Of those who received a CT-head (n = 279), 13 (4.7%) had acute findings. Of the encounters with acute findings, four (30.77%) had focal neurological deficits (FND), and two (15.38%) had Glasgow Coma Scale (GCS) score < 14. Patients without CT-head (n = 213) were more likely to be discharged (p < 0.01) and less likely to have a FND (p < 0.01). CONCLUSIONS: CT-head is ordered for over half of older ED patients with symptoms of delirium despite infrequent acute findings. Acute findings typically occur in the context of symptoms suggestive of intracranial abnormalities such as FND or GCS < 14. This suggests physicians should be more selective when ordering CT-heads in patients with symptoms of delirium.


Assuntos
Delírio , Serviço Hospitalar de Emergência , Humanos , Idoso , Estudos Retrospectivos , Delírio/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Tomografia , Escala de Coma de Glasgow
17.
Anal Chem ; 95(2): 1140-1148, 2023 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-36584277

RESUMO

Gaseous potassium (K) species play an important role in biomass combustion processes, and imaging techniques are powerful tools to investigate the related gas-phase chemistry. Here, laser absorption imaging of gaseous atomic K in flames is implemented using tunable diode laser absorption spectroscopy at 769.9 nm and a high-speed complementary metal oxide semiconductor (CMOS) camera recording at 30 kfps. Atomic K absorption spectra are acquired for each camera pixel in a field of view of 28 × 28 mm at a rate of 100 Hz. The technique is used to determine the spatial distribution of atomic K concentration during the conversion of potassium chloride (KCl) salt and wheat straw particles in a laminar premixed CH4/air flame with an image pixel resolution of up to 120 µm. Due to axisymmetry in setup geometry and, consequently, atomic K distributions, the radial atomic K concentration fields could be reconstructed by one-dimensional tomography. For the KCl sample, the K concentration field was in excellent agreement with previous point measurements. In the case of wheat straw, atomic K concentrations of around 3 ppm were observed in a cylindrical flame during devolatilization. In the char conversion phase, a spherical layer of atomic K, with concentrations reaching 25 ppm, was found within 5 mm of the particle surface, while the concentration rapidly decreased to sub-ppm levels along the vertical axis. In both cases, a thin (∼1 mm) layer without any atomic K was observed in close vicinity to the particle, suggesting that the potassium was initially not released in its atomic form.


Assuntos
Cloretos , Potássio , Cloreto de Potássio , Biomassa , Gases , Cloreto de Sódio , Lasers Semicondutores , Halogênios , Tomografia
18.
Waste Manag ; 157: 180-189, 2023 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-36563516

RESUMO

The accurate monitoring and early warning of groundwater pollution caused by the concealed leakage of landfills is a major challenge globally in the field of solid waste management and groundwater protection. Electrical resistivity tomography (ERT) represents a potential solution with advantages, owing to its fast and nondestructive characteristics. However, traditional ERT based on a single array cannot reveal the distribution and dynamics of pollution in complex underground media owing to the limited information it carries. We designed a novel deep network for multi-view fusion to invert the real resistivity distribution of the medium caused by leachate (named LDI-MVFNet) so as to infer the distribution of leachate. To support model establishment and validation, ERT instances collected from synthetic models and a salt tracer experiment were inverted. We compared the inversion results of the LDI-MVFNet with those of single arrays and found that the LDI-MVFNet performed the best overall. The average root mean square error (RMSE) of synthetic models reached 0.98, performing better than Dipole-Dipole (3.86), Wenner-Schlumberger (3.37), and Pole-Pole (6.61), which were inverted separately. The resultant inverted subsurface true resistivity data were presented in the form of two-dimensional (2D) cross sections. The imaging results of 2D cross sections showed that LDI-MVFNet was superior to others in data noise suppression and inversion accuracy. The results of this study indicate that the data fusion of multiple views can more accurately reflect the real resistivity than the inversion of a single array can.


Assuntos
Água Subterrânea , Gerenciamento de Resíduos , Poluentes Químicos da Água , Poluentes Químicos da Água/análise , Instalações de Eliminação de Resíduos , Resíduos Sólidos , Tomografia/métodos , Monitoramento Ambiental/métodos
20.
Respir Res ; 23(1): 374, 2022 Dec 23.
Artigo em Inglês | MEDLINE | ID: mdl-36564817

RESUMO

BACKGROUND: Targeted lung cancer screening is effective in reducing mortality by upwards of twenty percent. However, screening is not universally available and uptake is variable and socially patterned. Understanding screening behaviour is integral to designing a service that serves its population and promotes equitable uptake. We sought to review the literature to identify barriers and facilitators to screening to inform the development of a pilot lung screening study in Scotland. METHODS: We used Arksey and O'Malley's scoping review methodology and PRISMA-ScR framework to identify relevant literature to meet the study aims. Qualitative, quantitative and mixed methods primary studies published between January 2000 and May 2021 were identified and reviewed by two reviewers for inclusion, using a list of search terms developed by the study team and adapted for chosen databases. RESULTS: Twenty-one articles met the final inclusion criteria. Articles were published between 2003 and 2021 and came from high income countries. Following data extraction and synthesis, findings were organised into four categories: Awareness of lung screening, Enthusiasm for lung screening, Barriers to lung screening, and Facilitators or ways of promoting uptake of lung screening. Awareness of lung screening was low while enthusiasm was high. Barriers to screening included fear of a cancer diagnosis, low perceived risk of lung cancer as well as practical barriers of cost, travel and time off work. Being health conscious, provider endorsement and seeking reassurance were all identified as facilitators of screening participation. CONCLUSIONS: Understanding patient reported barriers and facilitators to lung screening can help inform the implementation of future lung screening pilots and national lung screening programmes.


Assuntos
Detecção Precoce de Câncer , Neoplasias Pulmonares , Humanos , Neoplasias Pulmonares/diagnóstico por imagem , Pulmão , Tomografia , Escócia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...