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1.
Ann Palliat Med ; 10(9): 9940-9952, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34628918

RESUMO

BACKGROUND: It is becoming more and more important to judge whether patients with coronary heart disease (CHD) have phlegm and blood stasis syndromes in the process of traditional Chinese medicine (TCM) diagnosis and treatment of CHD. The syndrome differentiation strategy of phlegm and blood stasis syndromes of CHD is still not standardized, and it is particularly necessary to make syndrome differentiation simpler and more accurate. METHODS: Twenty-eight medical cases that met the criteria, comprising 10 ancient medical cases and 18 modern ones, were selected from the TCM literature, which were then analyzed by 57 experts via questionnaire. Statistical analysis of the data was mainly based on frequency analysis. RESULTS: (I) The average age of the 57 experts from 20 provinces was 48.9±8.5 years; 89.5% were associate professor or above, and 75.4% of them worked at a tertiary hospital. (II) Consistency of expert consultation over medical cases: for the ancient medical cases, the diagnostic consistency rate of phlegm syndrome was 27/34 (79.4%) and additional diagnosis rate of the blood stasis syndrome was 27/57 (47.4%); for the modern medical cases, the consistency rate compared with the original diagnosis of phlegm syndrome was 54/80 (67.5%) and that of blood stasis syndrome was 73/90 (81.1%). (III) The top five experts' diagnostic basics of phlegm syndrome were oppression in the chest, slippery pulse, greasy fur, coughing of phlegm, and chest pain; the top five diagnostic basics of blood stasis syndrome were chest pain, dark tongue, oppression in chest, red tongue, and ecchymosis on tongue. (IV) In the questionnaire consultation on CHD phlegm-blood stasis syndrome cases, the diagnostic basis of "symptom or (and) tongue manifestation" accounted for 12/27 (44.4%) of the diagnostic basics of phlegm syndrome and 28/38 (73.7%) of that of blood stasis syndrome basis. CONCLUSIONS: Modern Chinese medicine experts pay much attention to the diagnosis and treatment of CHD based on TCM pathology theories of phlegm and blood stasis. To collect and detect the patients' symptoms and tongue manifestation is an important strategy of the experts for CHD phlegm and blood stasis syndrome differentiation.


Assuntos
Doença das Coronárias , Adulto , Doença das Coronárias/diagnóstico , Humanos , Medicina Tradicional Chinesa , Pessoa de Meia-Idade , Encaminhamento e Consulta , Síndrome , Língua
2.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 39(5): 510-517, 2021 Oct 01.
Artigo em Inglês, Chinês | MEDLINE | ID: mdl-34636197

RESUMO

OBJECTIVES: This study aims to investigate the effect of RhoE expression on the migration and invasion of tongue squamous cell carcinoma (TSCC). METHODS: Forty-eight TSCC cases were selected from the Maxillofacial Surgery Center of Qingdao Municipal Hospital from 2017 to 2019. The expression of RhoE in the specimens (TSCC and adjacent tissues) was detected by immunohistochemistry, and RhoE mRNA and protein were extracted to further detect the expression of RhoE. SCC-4 and CAL-27 cells were selected for in vitro experiments. Transient transfection was used to overexpress RhoE. Real-time fluorescence quantitative PCR (qRT-PCR) and Western blot analyses were conducted to detect the overexpression efficiency. Scratch test and Transwell cell invasion tests were used to detect the migration and invasion ability of TSCC, respectively. The expression levels of Rho-associated coiled-coil-containing protein kinase 1 (ROCK1), matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) were detected by Western blot. Experimental data were analyzed by Graphpad prism 8.2.1 software. RESULTS: The expression level of RhoE in TSCC was significantly lower than that in adjacent tissues (P<0.05). The migration and invasion abilities of TSCC were significantly lower than those in the control group (P<0.05). The Western blot showed significantly lower expression levels of ROCK1, MMP-2, and MMP-9 in the experimental group than in the control group (P<0.05). CONCLUSIONS: RhoE expression is low in TSCC. Over expression RhoE in TSCC can significantly decrease its migration and invasion abilities. Hence, RhoE may play an important role in regulating the metastasis and invasion of TSCC and provide a new target for gene therapy.


Assuntos
Carcinoma de Células Escamosas , Neoplasias da Língua , Linhagem Celular Tumoral , Humanos , Metaloproteinase 2 da Matriz , Invasividade Neoplásica , Língua , Quinases Associadas a rho
3.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 39(5): 540-546, 2021 Oct 01.
Artigo em Inglês, Chinês | MEDLINE | ID: mdl-34636201

RESUMO

OBJECTIVES: This study aims to explore the effect of acidic culture conditions on the proliferation, apoptosis, and migration ability of human tongue squamous cell carcinoma SCC15 and CAL27 cells and its potential molecular mechanism. METHODS: After acidic culture for different periods, methyl thiazolyl tetrazolium (MTT) method was adop-ted to detect the cell proliferation of SCC15 and CAL27. Flow cytometry was employed to detect the apoptosis level of SCC15 and CAL27 cells. The migration ability of SCC15 and CAL27 after acidic culture was detected by scratch hea-ling test. Real-time fluorescence quantitative polymerase chain reaction (FQ-PCR) was used to detect the mRNA expression of cyclooxygenase 2 (COX-2) and survivin in SCC15 and CAL27 cells after acidic culture. RESULTS: After culture for 24 h under acidic microenvironment, SCC15 and CAL27 cells grew rapidly and reached the stationary phase after adjustment for 3 days. The apoptosis levels of SCC15 and CAL27 cells decreased after acidic culture, but the most significant reduction occurred after 6 h of acidic culture. The scratch healing rates of SCC15 and CAL27 cells increased after acidic culture. The results of FQ-PCR showed that the mRNA expression levels of COX-2 and survivin in SCC15 and CAL27 cells increased after acidic culture. CONCLUSIONS: Extracellular acidic microenvironment can inhibit the apoptosis of tongue squamous carcinoma cells, promote their migration, and induce more adaptable and malignant tongue squamous carcinoma cells. The mechanism may be related to COX-2 and survivin and their signal pathways.


Assuntos
Carcinoma de Células Escamosas , Neoplasias Bucais , Neoplasias da Língua , Apoptose , Linhagem Celular Tumoral , Proliferação de Células , Humanos , Língua , Microambiente Tumoral
4.
Ned Tijdschr Tandheelkd ; 128(9): 429-433, 2021 Sep.
Artigo em Holandês | MEDLINE | ID: mdl-34490767

RESUMO

A 41-year-old woman, who was referred with a reddish purple like lesion on the left side of the tongue, appeared to have an angiokeratoma after histopathological examination. Because of the benign character of this lesion and the absence of any complaints, no adjuvant treatment after excisional biopsy was indicated. Angiokeratomas rarely appear as solitary oral lesions. More often they are seen as part of an underlying systemic disease, mostly Fabry disease. Due to widespread skin involvement of angiokeratomas with Fabry disease, referral to a dermatologist is indicated when oral lesions are encountered. Esthetically unpleasing or painful angiokeratomas can be locally excised or treated by laser- or cryotherapy.


Assuntos
Angioceratoma , Neoplasias Cutâneas , Adulto , Angioceratoma/diagnóstico , Biópsia , Feminino , Humanos , Neoplasias Cutâneas/diagnóstico , Língua
6.
BMC Oral Health ; 21(1): 475, 2021 09 27.
Artigo em Inglês | MEDLINE | ID: mdl-34579690

RESUMO

BACKGROUND: The aim of the study was to analyze the morphology and position of the tongue and hyoid bone in skeletal Class II patients with different vertical growth patterns by cone beam computed tomography in comparison to skeletal Class I patients. METHODS: Ninety subjects with malocclusion were divided into skeletal Class II and Class I groups by ANB angles. Based on different vertical growth patterns, subjects in each group were divided into 3 subgroups: high-angle group (MP-FH ≥ 32.0°), average-angle group (22.0° ≤ MP-FH < 32°) and low-angle group (MP-FH < 22°). The position and morphology of the tongue and hyoid bone were evaluated in the cone beam computed tomography images. The independent Student's t-test was used to compare the position and morphology of the tongue and hyoid bone between skeletal Class I and Class II groups. One-way analysis of variance (ANOVA) was used to compare the measurement indexes of different vertical facial patterns in each group. RESULTS: Patients in skeletal Class II group had lower tongue posture, and the tongue body was smaller than that of those in the Class I group (P < 0.05). The position of the hyoid bone was lower in the skeletal Class II group than in Class I group (P < 0.05). The tongue length and H-Me in the skeletal Class I group with a low angle were significantly larger than those with an average angle and high angle (P < 0.05). There was no significant difference in the position or morphology of the tongue and hyoid bone in the skeletal Class II group with different vertical facial patterns (P > 0.05). CONCLUSION: Patients with skeletal Class II malocclusion have lower tongue posture, a smaller tongue body, and greater occurrence of posterior inferior hyoid bone position than skeletal Class I patients. The length of the mandibular body in skeletal Class I patients with a horizontal growth type is longer. The position and morphology of the tongue and hyoid bone were not greatly affected by vertical facial development in skeletal Class II patients.


Assuntos
Má Oclusão Classe III de Angle , Má Oclusão Classe II de Angle , Má Oclusão , Cefalometria , Tomografia Computadorizada de Feixe Cônico , Humanos , Osso Hioide/diagnóstico por imagem , Má Oclusão Classe II de Angle/diagnóstico por imagem , Má Oclusão Classe III de Angle/diagnóstico por imagem , Mandíbula/diagnóstico por imagem , Língua/diagnóstico por imagem
7.
J Oral Sci ; 63(4): 330-333, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34470988

RESUMO

PURPOSE: To evaluate masticatory performance (MP), maximum occlusal force (MOF), maximum tongue pressure (MTP) and oral diadochokinesis (ODK) among community-dwelling elderly patients without posterior occlusal support. METHODS: This study enrolled community-dwelling elderly patients (≥65 years old) who belonged to Eichner A, B4, C1, C2, and C3. Each oral function was statistically compared among groups. Correlations between MP and other variables were examined in Eichner B4 and C patients. RESULTS: MP and MOF values in Eichner B4 and C patients were significantly lower than in Eichner A patients. There were significant differences in MTP values between Eichner "A and C2, C3", and "B4 and C2, C3". ODK in Eichner C patients showed significantly lower values compared to Eichner A patients in general. Although there were statistically significant correlations of MP with age, the number of remaining teeth and all oral functions were identified, and multiple regression analysis indicated that MOF and MTP were independently related to MP. CONCLUSION: Oral functions in Eichner B4 and C patients were lower compared to Eichner A patients. MP was significantly correlated with MOF and MTP in elderly patients without posterior occlusal support, suggesting the importance of rehabilitation of MOF and MTP in MP.


Assuntos
Vida Independente , Mastigação , Idoso , Força de Mordida , Humanos , Pressão , Língua
8.
BMJ Case Rep ; 14(9)2021 Sep 20.
Artigo em Inglês | MEDLINE | ID: mdl-34544699

RESUMO

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.


Assuntos
Tumor de Células Granulares , Neoplasias da Língua , Tumor de Células Granulares/diagnóstico por imagem , Tumor de Células Granulares/cirurgia , Humanos , Mucosa Bucal , Recidiva Local de Neoplasia , Língua
9.
Comput Biol Med ; 137: 104782, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34520987

RESUMO

Non-invasive multi-disease detection is an active technology that detects human diseases automatically. By observing images of the human body, computers can make inferences on disease detection based on artificial intelligence and computer vision techniques. The sublingual vein, lying on the lower part of the human tongue, is a critical identifier in non-invasive multi-disease detection, reflecting health status. However, few studies have fully investigated non-invasive multi-disease detection via the sublingual vein using a quantitative method. In this paper, a two-phase sublingual-based disease detection framework for non-invasive multi-disease detection was proposed. In this framework, sublingual vein region segmentation was performed on each image in the first phase to achieve the region with the highest probability of covering the sublingual vein. In the second phase, features in this region were extracted, and multi-class classification was applied to these features to output a detection result. To better represent the characterisation of the obtained sublingual vein region, multi-feature representations were generated of the sublingual vein region (based on color, texture, shape, and latent representation). The effectiveness of sublingual-based multi-disease detection was quantitatively evaluated, and the proposed framework was based on 1103 sublingual vein images from patients in different health status categories. The best multi-feature representation was generated based on color, texture, and latent representation features with the highest accuracy of 98.05%.


Assuntos
Inteligência Artificial , Soalho Bucal , Algoritmos , Humanos , Soalho Bucal/diagnóstico por imagem , Língua/diagnóstico por imagem
10.
Codas ; 33(4): e20200106, 2021.
Artigo em Português, Inglês | MEDLINE | ID: mdl-34550214

RESUMO

PURPOSE: This study investigated the self-perception of 49 women, monolingual speakers of Brazilian Portuguese, about their tongue position for the alveolar articulation of the fricatives [s] and [z]. METHODS: The video recording of speech samples of these 49 women (ages 18 to 28) were analyzed by three Speech-Language Pathologists. They were classified into two groups: Group 1 (G1, n=25), with no alterations in the tongue position during the production of [s] and [z], and Group 2 (G2, n=24), with alterations in the tongue position during the production of [s] and [z]. The tongue position self-perception experiment required the participants to identify the specific tongue constriction point in the production of [s] and [z] (apical, laminal, or "other") during the reading of 24 words and 24 pseudowords. The Friedman test, with posterior paired comparisons, was used for the intragroup analysis. The Mann-Whitney test was used for intergroup comparisons. The statistical significance adopted was 5% (p<0.05). RESULTS: G1 reported apical and laminal tongue constrictions while GE reported these constrictions plus other tongue adjustments. The presence of other tongue adjustments differentiated the groups, G1 and G2 (p=0,002). There were significant differences between [s] and [z] for G1, with the laminal position occurring more often in [s] compared to [z]. CONCLUSION: Women with and without alteration in the tongue position reported apical and laminal constrictions. Howerer, other tongue adjustments were self-perceived in the presence of altered tongue position.


Assuntos
Fonética , Língua , Adolescente , Adulto , Constrição , Feminino , Humanos , Autoimagem , Fala , Medida da Produção da Fala , Adulto Jovem
11.
J Pak Med Assoc ; 71(9): 2271-2274, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34580530

RESUMO

Distant metastasis is the most important prognostic factor for head and neck cancer. This report presents the case of a 50-year-old man with distant metastasis of tongue carcinoma to the vastus lateralis muscle which presented to Nihon University Itabashi Hospital, Tokyo, Japan. Tumourectomy was performed with a diagnosis of tongue carcinoma (cT2N0M0, Stage II). Seven months later, radical neck dissection was performed for lymph node metastasis to a left supraclavicular lymph node. In addition, metastasis was then detected outside the neck dissection region. Tumourectomy and radiotherapy (50 Gy) were, therefore, added to the treatment regimen. However, left-sided vastus lateralis muscle metastasis was then observed. To the best of our knowledge, this is the first report of distant metastasis of oral squamous cell carcinoma to the vastus lateralis muscle.


Assuntos
Carcinoma de Células Escamosas , Neoplasias de Cabeça e Pescoço , Neoplasias Bucais , Neoplasias da Língua , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/cirurgia , Humanos , Linfonodos/patologia , Masculino , Pessoa de Meia-Idade , Esvaziamento Cervical , Estadiamento de Neoplasias , Músculo Quadríceps , Língua , Neoplasias da Língua/patologia , Neoplasias da Língua/cirurgia
12.
Artigo em Inglês | MEDLINE | ID: mdl-34444456

RESUMO

Stroke is a devastating condition that may cause upper limb paralysis. Robotic rehabilitation with self-initiated and assisted movements is a promising technology that could help restore upper limb function. Previous studies have established that the tongue motion can be used to communicate human intent and control a rehabilitation robot/assistive device. The goal of this study was to evaluate a tongue-operated exoskeleton system (TDS-KA), which we have developed for upper limb rehabilitation. We adopted a tongue-operated assistive technology, called the tongue drive system (TDS), and interfaced it with the exoskeleton KINARM. We also developed arm reaching and tracking tasks, controlled by different tongue operation modes, for training and evaluation of arm motor function. Arm reaching and tracking tasks were tested in 10 healthy participants (seven males and three females, 23-60 years) and two female stroke survivors with upper extremity impairment (32 and 58 years). All healthy and two stroke participants successfully performed the tasks. One stroke subject demonstrated a clinically significant improvement in Fugl-Meyer upper extremity score after practicing the tasks in six 3-h sessions. We conclude that the TDS-KA system can accurately translate tongue commands to exoskeleton arm movements, quantify the function of the arm, and perform rehabilitation training.


Assuntos
Exoesqueleto Energizado , Reabilitação do Acidente Vascular Cerebral , Feminino , Humanos , Masculino , Língua , Resultado do Tratamento , Extremidade Superior
14.
J Exp Biol ; 224(7)2021 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-34424975

RESUMO

Mastication and drinking are rhythmic and cyclic oral behaviors that require interactions between the tongue, jaw and a food or liquid bolus, respectively. During mastication, the tongue transports and positions the bolus for breakdown between the teeth. During drinking, the tongue aids in ingestion and then transports the bolus to the oropharynx. The objective of this study was to compare jaw and tongue kinematics during chewing and drinking in pigs. We hypothesized there would be differences in jaw gape cycle dynamics and tongue protraction-retraction between behaviors. Mastication cycles had an extended slow-close phase, reflecting tooth-food-tooth contact, whereas drinking cycles had an extended slow-open phase, corresponding to tongue protrusion into the liquid. Compared with chewing, drinking jaw movements were of lower magnitude for all degrees of freedom examined (jaw protraction, yaw and pitch), and were bilaterally symmetrical with virtually no yaw. The magnitude of tongue protraction-retraction (Txt), relative to a mandibular coordinate system, was greater during mastication than during drinking, but there were minimal differences in the timing of maximum and minimum Txt relative to the jaw gape cycle between behaviors. However, during drinking, the tongue tip is often located outside the oral cavity for the entire cycle, leading to differences between behaviors in the timing of anterior marker maximum Txt. This demonstrates that there is variation in tongue-jaw coordination between behaviors. These results show that jaw and tongue movements vary significantly between mastication and drinking, which hints at differences in the central control of these behaviors.


Assuntos
Arcada Osseodentária , Mastigação , Animais , Fenômenos Biomecânicos , Ingestão de Líquidos , Movimento , Suínos , Língua
15.
Sensors (Basel) ; 21(15)2021 Jul 22.
Artigo em Inglês | MEDLINE | ID: mdl-34372213

RESUMO

Conducting polymers (CPs) are extensively studied due to their high versatility and electrical properties, as well as their high environmental stability. Based on the above, their applications as electronic devices are promoted and constitute an interesting matter of research. This review summarizes their application in common electronic devices and their implementation in electronic tongues and noses systems (E-tongues and E-noses, respectively). The monitoring of diverse factors with these devices by multivariate calibration methods for different applications is also included. Lastly, a critical discussion about the enclosed analytical potential of several conducting polymer-based devices in electronic systems reported in literature will be offered.


Assuntos
Técnicas Biossensoriais , Polímeros , Nariz Eletrônico , Eletrônica , Língua
16.
Sensors (Basel) ; 21(15)2021 Jul 26.
Artigo em Inglês | MEDLINE | ID: mdl-34372298

RESUMO

The aim of this study is to establish the usefulness of an electronic tongue based on cyclic voltammetry e-tongue using five working electrodes (gold, silver, copper, platinum and glass) in honey adulteration detection. Authentic honey samples of different botanical origin (acacia, tilia, sunflower, polyfloral and raspberry) were adulterated with agave, maple, inverted sugar, corn and rice syrups in percentages of 5%, 10%, 20% and 50%. The silver and copper electrodes provided the clearest voltammograms, the differences between authentic and adulterated honey samples being highlighted by the maximum current intensity. The electronic tongue results have been correlated with physicochemical parameters (pH, free acidity, hydroxymethylfurfural content-5 HMF and electrical conductivity-EC). Using statistical methods such as Linear discriminant analysis (LDA) and Support vector machines (SVM), an accuracy of 94.87% and 100% respectively was obtained in the calibration step and 89.65% and 100% respectively in the validation step. The PLS-R (Partial Least Squares Regression) model (constructed from the minimum and maximum current intensity obtained for all electrodes) was used in physicochemical parameters prediction; EC reached the highest regression coefficients (0.840 in the calibration step and 0.842 in the validation step, respectively), being followed by pH (0.704 in the calibration step and 0.516 in the validation step, respectively).


Assuntos
Mel , Análise Discriminante , Contaminação de Alimentos/análise , Mel/análise , Análise dos Mínimos Quadrados , Língua
17.
Exp Gerontol ; 153: 111505, 2021 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-34343633

RESUMO

OBJECTIVES: To investigate age-related changes in the intramuscular adipose tissue (IAT) of the tongue and geniohyoid muscle (GHM) and associated factors. DESIGN: Exploratory cross-sectional study. SETTING AND PARTICIPANTS: This study included 89 participants recruited from a health survey, which included 38 younger adults (age range, 20-63 years) and 51 older adults (age range, 65-87 years). MEASUREMENTS: Age, body mass index, body fat, lean body mass, skeletal muscle mass index, trunk muscle mass index, tongue pressure, jaw opening force, and oral diadochokinesis were assessed. The cross-sectional area (CSA) and echo intensity (EI) of the tongue and GHM were measured using ultrasonography. IAT was assessed according to EI values. The factors related to the IAT of each muscle were examined using multiple regression analysis. We also investigated the correlation of IAT with factors related to oral function and systemic and morphological factors. RESULTS: Neither the EI of the tongue nor that of the GHM had a significant correlation with factors related to oral function and systemic factors. In the multiple regression analysis, significant explanatory variables for EI of the tongue and GHM were age (ß = 0.14, P = 0.019; tongue and ß = 0.13, P = 0.017; GHM) and the CSA of each muscle (ß = -0.01, P = 0.042; tongue and ß = -0.04, P = 0.003; GHM). EI was positively associated with age and negatively associated with muscle CSA. CONCLUSION: Age-related changes in the IAT show the same trend for both the tongue and GHM, unlike age-related changes in muscle mass. The IATs of the tongue and GHM were not significantly correlated with oral function and systemic factors. Therefore, EI may not be a useful index for the functional evaluation of the tongue and GHM.


Assuntos
Deglutição , Força Muscular , Tecido Adiposo/diagnóstico por imagem , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Humanos , Músculo Esquelético , Pressão , Língua/diagnóstico por imagem
18.
J Oral Rehabil ; 48(10): 1173-1182, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34346106

RESUMO

BACKGROUND: Oral hypofunction is defined as the reversible stage preceding oral dysfunction. However, its assessment and management need further examination and consideration. OBJECTIVE: The present study aimed to examine the current state of oral hypofunction among outpatients at the university hospital. METHODS: New outpatients underwent medical interviews and detailed assessment of oral hypofunction at their initial visit to our dental department. Oral hypofunction was diagnosed if the results of three of the following seven assessment items were below cut-off values: poor oral hygiene, oral dryness, reduced occlusal force, decreased tongue-lip motor function, decreased tongue pressure, decreased masticatory function and deterioration of swallowing function. The relationships between factors used to diagnose oral hypofunction as well as the distributions of assessment values were clarified. RESULTS: Seventy-five of 209 patients (35.9%) were finally diagnosed with oral hypofunction. Diagnosis of oral hypofunction was significantly related to patient age, Eichner index, a chief complaint of dental or periodontal disease or ill-fitting dentures and a history of neurodegenerative disease. The lowest quintile values for poor oral hygiene, oral dryness and decreased masticatory performance were all above current cut-off values. Reduced occlusal force contributed strongly to the diagnosis of oral hypofunction. CONCLUSION: Oral hypofunction in dental outpatients at a university hospital was associated with patient age, medical history and chief complaint at presentation. Diagnosis of oral hypofunction can be closely related to reduced occlusal force. The validity of cut-off values for assessments of oral hypofunction needs further consideration.


Assuntos
Doenças Neurodegenerativas , Pacientes Ambulatoriais , Idoso , Estudos Transversais , Hospitais , Humanos , Pressão , Língua
19.
Nutrients ; 13(7)2021 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-34371947

RESUMO

Nutritional status is well-known to influence patient recovery after resection of head and neck cancer (HNC). The influence of preoperative nutritional status on dysphagia was assessed in patients who underwent surgical resection of HNC along with the assessment of nutritional status during the acute and subacute phases. Eighty-six patients underwent surgical resection and dysphagia assessments (repetitive saliva-swallowing test, water-swallowing test, and functional oral intake scale) and had their tongue pressure assessed five times (before surgery, after 1-2 weeks, and 1, 2, and 3 months after surgery). The nutritional status was assessed according to the body mass index, total protein, and albumin. The prognostic nutritional index was calculated from preoperative data, and the subjects were classified into three groups: Low-risk, Attention and High-risk groups. After surgery, the nutritional status index values were low, and the High-risk group showed significantly lower values in comparison to the other two groups. The water-swallowing test and functional oral intake scale findings were worse than they had been preoperatively until 2 months after surgery, and a significant correlation was noted between the postoperative nutritional status and the presence of dysphagia. The results indicated that the preoperative nutritional status of HNC patients influenced their ability to ingest/swallow, which in turn influenced their nutritional status after HNC resection.


Assuntos
Transtornos de Deglutição/etiologia , Neoplasias de Cabeça e Pescoço/complicações , Neoplasias de Cabeça e Pescoço/cirurgia , Estado Nutricional , Idoso , Deglutição , Ingestão de Alimentos , Feminino , Neoplasias de Cabeça e Pescoço/fisiopatologia , Humanos , Masculino , Avaliação Nutricional , Complicações Pós-Operatórias , Período Pós-Operatório , Período Pré-Operatório , Pressão , Estudos Prospectivos , Língua
20.
Artif Intell Med ; 118: 102110, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-34412836

RESUMO

OBJECTIVE: Using the deep learning model to realize tongue image-based disease location recognition and focus on solving two problems: 1. The ability of the general convolution network to model detailed regional tongue features is weak; 2. Ignoring the group relationship between convolution channels, which caused the high redundancy of the model. METHODS: To enhance the convolutional neural networks. In this paper, a stochastic region pooling method is proposed to gain detailed regional features. Also, an inner-imaging channel relationship modeling method is proposed to model multi-region relations on all channels. Moreover, we combine it with the spatial attention mechanism. RESULTS: The tongue image dataset with the clinical disease-location label is established. Abundant experiments are carried out on it. The experimental results show that the proposed method can effectively model the regional details of tongue image and improve the performance of disease location recognition. CONCLUSION: In this paper, we construct the tongue image dataset with disease-location labels to mine the relationship between tongue images and disease locations. A novel fully-channel regional attention network is proposed to model the local detail tongue features and improve the modeling efficiency. SIGNIFICANCE: The applications of deep learning in tongue image disease-location recognition and the proposed innovative models have guiding significance for other assistant diagnostic tasks. The proposed model provides an example of efficient modeling of detailed tongue features, which is of great guiding significance for other auxiliary diagnosis applications.


Assuntos
Redes Neurais de Computação , Língua , Processamento de Imagem Assistida por Computador , Língua/diagnóstico por imagem
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