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1.
Curr Allergy Asthma Rep ; 21(4): 26, 2021 03 29.
Artigo em Inglês | MEDLINE | ID: mdl-33779825

RESUMO

PURPOSE OF REVIEW: This article aims to summarize some recent trends in occupational allergic contact dermatitis (ACD), including dermatitis related to pandemic-level personal protective equipment in healthcare workers, hazards patients may experience when working from home, and occupational perspectives on the recent American Contact Dermatitis Society (ACDS) allergens of the year and ACDS Core Allergen Series updates. RECENT FINDINGS: Recent ACDS Allergens of the Year may be particularly relevant to healthcare workers, including isobornyl acrylate, which is present in glucose sensors and propylene glycol present in hand cleansers and disinfectants. Lavender, limonene, and linalool, all of which are new additions to the ACDS Core Allergen Series, have been reported as causes for occupational ACD in massage therapists and aromatherapists. Isothiazolinone allergy continues to rise in both consumer and occupational settings. Finally, the COVID-19 pandemic has resulted in a wave of occupational ACD in healthcare workers to personal protective equipment, and revealed new potential allergens for individuals working from home. Occupational allergic contact dermatitis continues to exert a significant occupational disease burden. Remaining aware of the current trends in allergens may allow for earlier recognition, diagnosis, and treatment, subsequently helping our patients to work in healthier and safer environments.


Assuntos
Alérgenos/efeitos adversos , Dermatite Alérgica de Contato/diagnóstico , Dermatite Ocupacional/diagnóstico , Acrilatos , Monoterpenos Acíclicos/efeitos adversos , Alergia e Imunologia/tendências , Canfanos , Dermatite Ocupacional/etiologia , Dermatologia/tendências , Pessoal de Saúde , Humanos , Lavandula/efeitos adversos , Limoneno/efeitos adversos , Pandemias , Testes do Emplastro/efeitos adversos , Propilenoglicol , Sociedades Médicas , Estados Unidos
3.
J Immunol Methods ; 492: 112994, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33626382

RESUMO

The annual meeting of the Association of Medical Laboratory Immunologists (AMLI) was convened virtually over the month of August. Prior to the emergence of the COVID-19 pandemic, AMLI's scientific committee had chosen the following topics as the focus of its 2020 meeting: Histocompatibility Testing and Transplant Immunology; Secondary Immunodeficiency and Immunotherapy Monitoring; ANA Update; and Emerging Infectious Diseases and New Algorithms for Testing. Given the central role of the discipline in the evaluation of the host response to infection, it was apt to add a separate session on antibody testing for SARS-CoV-2 infections to the original program. The current report provides an overview of the subjects discussed in the course of this meeting.


Assuntos
Alergia e Imunologia , Imunoterapia/métodos , Sociedades Médicas , Algoritmos , Animais , Processos Grupais , Teste de Histocompatibilidade , Interações Hospedeiro-Patógeno , Humanos , Laboratórios , Pandemias , Imunologia de Transplantes , Realidade Virtual
7.
Allergol. immunopatol ; 49(1): 87-94, ene.-feb. 2021. tab, graf
Artigo em Inglês | IBECS | ID: ibc-199230

RESUMO

BACKGROUND: The Mexican Guidelines for the diagnosis and treatment of urticaria have been published. Just before their launch, physicians' knowledge was explored relating to key issues of the guidelines. OBJECTIVE: The aim of this study was to investigate the opinion of medical specialists concern­ing urticaria management. METHODS: A SurveyMonkey(R) survey was sent out to board-certified physicians of three medical specialties treating urticaria. Replies were analyzed per specialty against the evidence-based recommendations. RESULTS: Sixty-five allergists (ALLERG), 24 dermatologists (DERM), and 120 pediatricians (PED) sent their replies. As for diagnosis: ALERG 42% and PED 76% believe cutaneous mastocyto­sis, urticarial vasculitis, and hereditary angioedema are forms of urticaria, versus DERM 29% (P < 0.005). Most of the specialties find that the clinical history and physical examination are enough to diagnose acute urticaria, except DERM 45% (P < 0.01). DERM 45% believe laborato­ry-tests are necessary, as opposed to <15% ALLERG-PED (P < 0.005). However, PED 69% did not know that the most frequent cause of acute urticaria in children is infections, versus ALLERG- DERM 30% (P < 0.005). Many erroneously do laboratory testing in physical urticaria and ALLERG 51%, DERM 59%, and PED 37% do extensive laboratory testing in chronic spontaneous urticaria (CSU); many more PED 59% take Immunoglobulin G (IgG) against foods (P < 0.005). More than half of non-allergists do not know about autologous serum testing nor autoimmunity (P < 0.05). As for treatment, there were a few major gaps: when CSU was controlled, >75% prescribed antihistamines pro re nata, and > 85% gave first-generation antiH1 for insomnia. Finally, > 40% of DERM did not know that cyclosporine A, omalizumab, or other immunosuppressants could be used in recalcitrant cases. CONCLUSION: Specialty-specific continuous medical education might enhance urticaria management


No disponible


Assuntos
Humanos , Urticária/diagnóstico , Urticária/epidemiologia , Educação Médica Continuada/normas , Alergia e Imunologia/educação , Pediatria/educação , Dermatologia/educação , Urticária/imunologia , Guias de Prática Clínica como Assunto/normas , Imunoglobulina G/análise , Imunoglobulina G/imunologia , Comparação Transcultural , Urticária/classificação
12.
Nat Immunol ; 22(2): 111-117, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33495644

RESUMO

Laboratory mice have provided invaluable insight into mammalian immune systems. Yet the immune phenotypes of mice bred and maintained in conventional laboratory conditions often differ from the immune phenotypes of wild mammals. Recent work to naturalize the environmental experience of inbred laboratory mice-to take them where the wild things are (to borrow a phrase from Maurice Sendak), via approaches such as construction of exposure histories, provision of fecal transplants or surrogate mothering by wild mice, and rewilding-is poised to expand understanding, complementing genetic and phylogenetic research on how natural selection has shaped mammalian immune systems while improving the translational potential of mouse research.


Assuntos
Alergia e Imunologia , Pesquisa Biomédica , Meio Ambiente , Sistema Imunitário/fisiologia , Imunidade , Animais , Evolução Biológica , Biota , Interações Hospedeiro-Patógeno , Sistema Imunitário/microbiologia , Camundongos , Modelos Animais , Fenótipo
13.
Trends Immunol ; 42(2): 91-93, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33358277

RESUMO

Immunologists are central to fighting any pandemic. From pathogenesis to disease modeling, pharmaceuticals to vaccines, immunologists play a crucial role in translating basic science into effective response strategies. This article describes our view on how lessons from the coronavirus disease 2019 (COVID-19) pandemic can be developed into an immunologists' guide for preparedness for future pandemics.


Assuntos
Alergia e Imunologia/tendências , /imunologia , /fisiologia , Animais , Artrite Infecciosa/imunologia , Humanos , Imunidade , Pandemias , Guias de Prática Clínica como Assunto , Saúde Pública , Pesquisa Médica Translacional , Vacinação , Vacinas , Organização Mundial da Saúde
14.
Ann Allergy Asthma Immunol ; 126(3): 235-239, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33309885

RESUMO

OBJECTIVE: To review evidence-based strategies that have been noted to improve professional fulfillment and reduce burnout by enhancing practice efficiency. DATA SOURCES: A comprehensive literature review was conducted to evaluate the strategies to improve efficiency of practice-a key driver of burnout among physicians. STUDY SELECTIONS: Studies of efficiency-enhancing practices relevant to allergy-immunology were included. RESULTS: Professional burnout is prevalent among physicians and is associated with negative outcomes affecting physicians, patients, and health care organizations. Recent surveys suggest at least 35% of US allergists-immunologists experience burnout. There are multiple drivers of professional burnout, some at the individual level and others at the organizational or practice level. Strategies to improve professional fulfillment may be conceptualized using the Stanford physician wellness framework, in which efforts target the following 3 reciprocal domains: culture, personal resilience, and practice efficiency. Organizational strategies that support physician well-being by creating a more efficient practice environment hold great promise, particularly for allergists-immunologists. The reduction of administrative burden and fostering of team-based care have been found in multiple studies to be cost-effective strategies to improve physician and patient satisfaction. CONCLUSION: To ensure the well-being of the US allergy-immunology workforce and optimize patient outcomes, both private and academic allergy-immunology institutions should prioritize the adoption and iterative evaluation and refinement of these strategies to cocreate an efficient and ideal practice environment.


Assuntos
Alergia e Imunologia , Esgotamento Profissional/prevenção & controle , Eficiência Organizacional , Cultura Organizacional , Médicos/psicologia , Humanos , Satisfação no Emprego , Profissionalismo
15.
Ann Allergy Asthma Immunol ; 126(3): 219-227, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33326844

RESUMO

OBJECTIVE: There are 3 domains of physician wellness: (1) the culture of wellness, (2) efficiency of practice, and (3) physician resilience. The culture of wellness encompasses an organization's values, environment, and behaviors that foster compassion and growth in its physicians. DATA SOURCES: Studies have reported that burnout affects a physician's professionalism, altruism, and a sense of calling. Furthermore, burnout increases the risk of cardiovascular disease, alcohol abuse, divorce, depression, and even suicide among physicians. Physician burnout is associated with decreased efficiency at work, which can affect patient care, patient satisfaction, and even patient safety. As such, it is imperative that we develop a culture of wellness. STUDY SELECTIONS: A culture of wellness reflects shared values and a sense of community within an organization. When a culture of wellness is present, leaders prioritize the personal and professional growth of its team members. RESULTS: This article instructs readers on methods that can be used to develop a culture of wellness. CONCLUSION: We need to address burnout at every level in health care, namely at health care organization and system levels, individual teams and offices, and at an individual level. In doing so, it becomes obvious that a lack of wellness (burnout) is a systems problem and not an individual's fault. We are all responsible for taking steps to change the culture to one of wellness. Working within our practices, organization, and allergy societies, we can change the culture to one of wellness.


Assuntos
Alergia e Imunologia , Esgotamento Profissional/prevenção & controle , Saúde do Trabalhador , Cultura Organizacional , Médicos/psicologia , Humanos , Resiliência Psicológica , Equilíbrio Trabalho-Vida
16.
Immunology ; 162(1): 1-2, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33305861

RESUMO

2020 was a year unlike any other for Immunology. Through the SARS-CoV-2 pandemic, with fantastic support from the global immunology community, we worked together to reach new heights. Here, we look back at some of the highlights for Immunology in a challenging and memorable year.


Assuntos
Alergia e Imunologia/tendências , Pesquisa Biomédica/tendências , Publicações Periódicas como Assunto/tendências , Políticas Editoriais , Humanos , Disseminação de Informação , Fator de Impacto de Revistas
18.
Inmunología (1987) ; 39(4): 38-42, oct.-dic. 2020. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-200130

RESUMO

No disponible


Assuntos
Humanos , Alergia e Imunologia , Pandemias , Filmes Cinematográficos
19.
Cell ; 183(2): 308-314, 2020 10 15.
Artigo em Inglês | MEDLINE | ID: mdl-33064987

RESUMO

The 2020 Lasker Awards, a celebration of one of the most prestigious international prizes given to individuals for extraordinary contributions to Basic and Clinical Medical Research, Pubic Health, and Special Achievement, was cancelled because of the COVID-19 pandemic. Typically, essays on the awardees and their scientific and medical contributions are solicited and published in Cell in collaboration with the Lasker Committee. This year, the Lasker Committee commissioned an essay to reflect on the historic contributions that scientists and physicians have made to our understanding of immunology and virology, and future directions in medical and basic research that have been highlighted by COVID-19 pandemic.


Assuntos
Alergia e Imunologia , Betacoronavirus/imunologia , Infecções por Coronavirus/imunologia , Imunidade , Pneumonia Viral/imunologia , Alergia e Imunologia/história , Animais , Distinções e Prêmios , Citocinas/imunologia , História do Século XIX , História do Século XX , História do Século XXI , Humanos , Sistema Imunitário/citologia , Imunoglobulinas/genética , Imunoglobulinas/imunologia , Linfócitos/citologia , Pandemias , Vacinação/história
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