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Rev. latinoam. psicopatol. fundam ; 24(1): 188-199, jan.-mar. 2021.
Artículo en Inglés | LILACS-Express | LILACS, Index Psicología - Revistas | ID: biblio-1251909


North American writer David Foster Wallace wrote two short stories - The Planet Trillaphon As It Stands In Relation To The Bad Thing and The Depressed Person - that depict depression, in each one taking different yet complementary perspectives on this subject. Our aim is to analyze these texts and to discuss the role literature can have in regard to the apprehension of subjective experiences of others. Whereas the first text attempts to describe depression objectively, the second one describes the impossibility of doing so, focusing on literary techniques that create distressing subjective experiences in the reader, possibly resembling those felt by depressed persons. We suggest that literature might be helpful to comprehend some aspects of the experience of being depressed and that such an understanding may enrich psychiatric practice.

O escritor estadunidense David Foster Wallace escreveu dois contos - The Planet Trillaphon As It Stand In Relation To The Bad Thing e The Depressed Person - que abordam a temática da depressão, em cada um adotando perspectivas distintas e complementares. Nosso objetivo é analisar esses textos e discutir alguns aspectos do acesso à experiência subjetiva de outras pessoas, mais especificamente o papel da literatura nesse processo. Enquanto o primeiro texto descreve a depressão objetivamente, o segundo descreve a impossibilidade de fazer tal descrição, focando em técnicas literárias que criam experiências subjetivas desagradáveis, possivelmente semelhantes às sentidas pelas pessoas deprimidas. Nós sugerimos que a literatura pode ser útil na compreensão de alguns aspectos da experiência de estar deprimido, e que tal compreensão pode enriquecer a prática psiquiátrica.

L'écrivain nord-américain David Foster Wallace a écrit deux contes - « The Planet Trillaphon As It Stand In Relation To The Bad Thing ¼ et « The Depressed Person ¼ - abordant le thème de la dépression, en adoptant dans chacun de ces textes des perspectives distinctes et complémentaires. Notre but est de les analyser et de discuter certains aspects de l'accès à l'expérience subjective d'autres personnes, en nous intéressant tout particulièrement au rôle de la littérature dans ce processus. Alors que le premier texte décrit la dépression de façon objective, le second décrit l'impossibilité d'en faire une telle description, se concentrant sur des techniques littéraires créant des expériences subjectives désagréables, potentiellement semblables à celles ressenties par les personnes déprimées. Nous suggérons que la littérature peut être utile dans la compréhension de certains aspects de l'expérience de l'être déprimé et qu'une telle compréhension peut enrichir la pratique psychiatrique.

El escritor estadounidense David Foster Wallace escribió dos cuentos - The Planet Trillaphon As It Stand In Relation To The Bad Thing y The Depressed Person- que abordan la temática de la depresión y que adoptan perspectivas distintas y complementarias. Nuestro objetivo es analizar dichos textos y discutir algunos aspectos del acceso a la experiencia subjetiva de otras personas, más específicamente el papel de la literatura en ese proceso. Mientras que el primer texto describe la depresión objetivamente, el segundo describe la imposibilidad de hacer dicha descripción, centrándose en técnicas literarias que crean experiencias subjetivas desagradables, posiblemente semejantes a las sentidas por las personas deprimidas. Sugerimos que la literatura puede ser útil para la comprensión de algunos aspectos de la experiencia de estar deprimido, y que tal comprensión puede enriquecer la práctica psiquiátrica.

Methods Mol Biol ; 1997: 185-205, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31119625


High-throughput quantitative proteomics unravels secrets of Neisseria gonorrhoeae biology by profiling proteome responses to environmental and endogenous cues and opens translational research paths through identification of vaccine candidates, drug targets/virulence factors, and biomarkers. Bioinformatics tools and databases are indispensable for downstream analysis of proteomic datasets to generate biologically meaningful outcomes. In this chapter, we present a workflow for proteomic data analysis with emphasis on publicly available resources, software systems, and tools that predict protein subcellular localization (CELLO, PSORTb v3.0, SOSUI-GramN, SignalP 4.1, LipoP 1.0, TMHMM 2.0) and functional annotation (EggNOG-mapper 4.5.1., DAVID v6.8, and KEGG) of N. gonorrhoeae proteins. This computational step-by-step procedure may help to foster new hypotheses and to provide insights into the structure-function relationship of proteins.

Proteínas Bacterianas/genética , Neisseria gonorrhoeae/genética , Proteoma/genética , Proteómica/métodos , Bases de Datos de Proteínas , Conjuntos de Datos como Asunto , Ontología de Genes , Anotación de Secuencia Molecular , Programas Informáticos
Parasitology ; 145(13): 1641-1646, 2018 11.
Artículo en Inglés | MEDLINE | ID: mdl-30185237


The study of parasites typically crosses into other research disciplines and spans across diverse scales, from molecular- to populational-levels, notwithstanding promoting an understanding of parasites set within evolutionary time. Today, the 2030 Sustainable Development Goals (SDGs) help frame much of contemporary parasitological research, since parasites can be found in all ecosystems, blighting human, animal and plant health. In recognition of the multi-disciplinary nature of parasitological research, the 2017 Autumn Symposium of the British Society for Parasitology was held in London to provide a forum for novel exchange across medical, veterinary and wildlife fields of study. Whilst the meeting was devoted to the topic of parasitism, it sought to foster mutualism, the antithesis perhaps of parasitism, by forging new academic connections and social networks to exchange novel ideas. The meeting also celebrated the longstanding career of Professor David Rollinson, FLS in the award of the International Federation for Tropical Medicine Medal for his efforts spanning 40 years of parasitological research. Indeed, David has done so much to explore and promote the fascinating biology of parasitism, as exemplified by the 15 manuscripts contained within this Special Issue.

Parasitología/educación , Parasitología/tendencias , Animales , Congresos como Asunto , Humanos , Londres , Parásitos , Investigación , Medicina Tropical
J Med Humanit ; 39(1): 15-27, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-28956347


In 1997, David Foster Wallace published "The Depressed Person," a short story about a privileged, deeply unhappy woman dedicated to exploring and recounting the texture and etiology of her chronic depression. This essay argues that "The Depressed Person" challenges the long-standing assumption that narrativizing the pain of depression is crucial to overcoming it, and the contemporary view that empathic responses from others promote recovery of the depressed. Taken together, these two critiques inform Wallace's portrayal of chronic depression as an interactive phenomenon that is articulated, sustained, and regenerated through problematic contexts of interaction. Written at a time when public knowledge of and talk about depression was surging, "The Depressed Person" holds an important, if presently under-recognized place, in the expansive corpus of depression texts that emerged in the 1990s.

Trastorno Depresivo/terapia , Empatía , Medicina Narrativa , Humanos , Literatura
Eval Program Plann ; 63: 136-137, 2017 08.
Artículo en Inglés | MEDLINE | ID: mdl-27940050


The quest for credible and actionable evidence to improve decision making, foster improvement, enhance self-determination, and promote social betterment is now a global phenomenon. Evaluation theorists and practitioners alike have responded to and overcome the challenges that limited the effectiveness and usefulness of traditional evaluation approaches primarily focused on seeking rigorous scientific knowledge about social programs and policies. No modern evaluation approach has received a more robust welcome from stakeholders across the globe than empowerment evaluation. Empowerment evaluation has been a leader in the development of stakeholder involvement approaches to evaluation, setting a high bar. In addition, empowerment evaluation's respect for community knowledge and commitment to the people's right to build their own evaluation capacity has influenced the evaluation mainstream, particularly concerning evaluation capacity building. Empowerment evaluation's most significant contributions to the field have been to improving evaluation use and knowledge utilization.

Estudios de Evaluación como Asunto , Humanos , Poder Psicológico , Evaluación de Programas y Proyectos de Salud
Integr Comp Biol ; 56(6): 1047-1054, 2016 12.
Artículo en Inglés | MEDLINE | ID: mdl-27591249


Crustaceans, and decapods in particular (i.e., crabs, shrimp, and lobsters), are a diverse and ecologically and commercially important group of organisms. Understanding responses to abiotic and biotic factors is critical for developing best practices in aquaculture and assessing the effects of changing environments on the biology of these important animals. A relatively small number of decapod crustacean species have been intensively studied at the molecular level; the availability, experimental tractability, and economic relevance factor into the selection of a particular species as a model. Transcriptomics, using high-throughput next generation sequencing (NGS, coupled with RNA sequencing or RNA-seq) is revolutionizing crustacean biology. The 11 symposium papers in this volume illustrate how RNA-seq is being used to study stress response, molting and limb regeneration, immunity and disease, reproduction and development, neurobiology, and ecology and evolution. This symposium occurred on the 10th anniversary of the symposium, "Genomic and Proteomic Approaches to Crustacean Biology", held at the Society for Integrative and Comparative Biology 2006 meeting. Two participants in the 2006 symposium, the late Paul Gross and David Towle, were recognized as leaders who pioneered the use of molecular techniques that would ultimately foster the transcriptomics research reviewed in this volume. RNA-seq is a powerful tool for hypothesis-driven research, as well as an engine for discovery. It has eclipsed the technologies available in 2006, such as microarrays, expressed sequence tags, and subtractive hybridization screening, as the millions of "reads" from NGS enable researchers to de novo assemble a comprehensive transcriptome without a complete genome sequence. The symposium series concludes with a policy paper that gives an overview of the resources available and makes recommendations for developing better tools for functional annotation and pathway and network analysis in organisms in which the genome is not available or is incomplete.

Biología Computacional/tendencias , Crustáceos/genética , Animales , Congresos como Asunto , Transcriptoma/genética
Laryngorhinootologie ; 95 Suppl 1: S6-S12, 2016 Apr.
Artículo en Alemán | MEDLINE | ID: mdl-27128405


BACKGROUND: Treating patients requires the inclusion of existing evidence in any health care decision, to be able to choose the best diagnosis or treatment measure or to make valid prognosis statements for a particular patient in consideration of the physician's own expertise.The basis are clinical trials, the results of which are ideally gathered in systematic reviews, rated, summarized and published. In addition to the GCP (Good Clinical Practice)-compliant planning, conducting and analysis of clinical studies it is essential, that all study results are made publicly available, in order to avoid publication bias. This includes the public registration of planned and discontinued trials. HISTORY: In the last 25 years, the evidence-based medicine (EbM) has increasingly found its way into clinical practice and research. Here EbM is closely associated with the names Archibald Cochrane and David Sackett. In Germany, both the German Cochrane Centre (DCZ) and the network of evidence-based medicine (DNEbM) were established approximately 15 years ago. In the international Cochrane Collaboration clinicians and other scientists like statisticians interdisciplinary work side by side to develop the methods of evidence-based medicine and to address the topics of evidence generation and processing as well as the transfer of knowledge. Challenge: Existing evidence primarily serves doctors to support their decision-making, but is also the basis for providing scientific proof for a health care intervention's benefit to patients and ultimately payers/health insurances. The closure of existing evidence gaps requires substantial human and financial resources, a complex organizational structure and can only succeed with the involvement of clinical and methodological expertise and specific knowledge in the field of clinical research. In addition, the knowledge must be transferred into practice, using journals, guidelines, conferences, databases, information portals with processed evidence and not least the medical education of students.One problem is the wealth of information, so that in clinical practice there may be gaps in knowledge of actual evidence. Usually it still takes several years until new knowledge is fully implemented in daily practice. OBJECTIVES: The German Society of Otolaryngology, Head and Neck Surgery (DGHNOKHC) and the German professional association of otolaryngologists (BVHNO) have a vested interest in supporting their members in the generation, processing and dissemination of evidence, and to foster the transfer of knowledge into practice. This includes the areas of diagnosis, treatment, prognosis and prevention as well as drug therapies or the application of medical devices or surgical procedures. Crucial is the regular determination of existing evidence gaps, including in the area of already established procedures, which must be followed by a prioritization of research questions and subsequent conduct of clinical research. Only with combined efforts even large trials can be performed, to test therapies and diagnostics for example, also after approval under everyday conditions. Methods, Results and Vision: The executive committees of DGHNOKHC and BVHNO have together founded the German Clinical Trials Unit for Ear, Nose and Throat medicine, Head and Neck Surgery (DSZ-HNO) to assist their members in the identification of evidence gaps and the planning and conduct of systematic reviews and clinical trials. The first projects have been started, including a BMBF(German Ministry for education and research)-funded clinical trial for the treatment of sudden hearing loss and a survey to detect evidence gaps in Otolaryngology. It seems both reasonable and feasible to provide a structure such as a jointly-run study center for doctors in hospitals and medical practices to assist in clinical research and to anchor the principles of evidence-based medicine in daily life.

Atención a la Salud , Medicina Basada en la Evidencia , Alemania , Humanos , Apoyo Social , Encuestas y Cuestionarios
Camb Q Healthc Ethics ; 24(1): 96-106, 2015 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-25473862


In Wallace's short story "Luckily the Account Representative Knew CPR," a vice president (VP) suffers cardiac arrest. As an account representative (AR) administers CPR, he discovers his own impersonality mirrored back to him by the VP-a disturbing vision of himself that the AR wishes to escape. Because modern moral theories would have the AR respond impersonally to the VP, those theories would only exacerbate his existential predicament. In contrast, by regarding the AR's act as one that he, in particular, should perform, narrative ethics can discern a resolution for his predicament: because the AR still values his diminished capacities for care and spontaneity, this situation offers him an opportunity to revive those former traits. Doing so would give him greater authentic integrity, or narrative continuity with the most important aspects of his past. Authentic integrity can serve narrative ethics as a helpful starting point for understanding how the life stories of patients, clinicians, and others might appropriately unfold.

Cuenta Bancaria/historia , Reanimación Cardiopulmonar/historia , Teoría Ética/historia , Paro Cardíaco/historia , Narración/historia , Personajes , Paro Cardíaco/terapia , Historia del Siglo XX , Historia del Siglo XXI , Humanos , Medicina en la Literatura , Estados Unidos
mBio ; 3(4): e00144-12, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22829677


UNLABELLED: We have shown that the herpes simplex virus 1 (HSV-1) gK gene is essential for efficient replication and spread in the corneal epithelium and trigeminal ganglion neuroinvasion in mice (A. T. David, A. Baghian, T. P. Foster, V. N. Chouljenko, and K. G. Kousoulas, Curr. Eye Res. 33:455-467, 2008). To further investigate the role of gK in neuronal infection, we utilized a microfluidic chamber system separating neuronal cell bodies and axonal termini. HSV-1 (McKrae) engineered virus constitutively expressing enhanced green fluorescence protein (GFP) was efficiently transmitted in both a retrograde and an anterograde manner. These results were corroborated by expression of virion structural proteins in either chamber, as well as detection of viral genomes and infectious viruses. In contrast, efficient infection of either chamber with a gK-null virus did not result in infection of the apposed chamber. These results show that gK is an important determinant in virion axonal infection. Moreover, the inability of the gK-null virus to be transmitted in an anterograde manner suggests that virions acquire cytoplasmic envelopes prior to entering axons. IMPORTANCE: Herpes simplex virus 1 (HSV-1) enters mucosal epithelial cells and neurons via fusion of the viral envelope with cellular membranes, mediated by viral glycoprotein B (gB) in cooperation with other viral glycoproteins. Retrograde transport of virions to neuronal cell bodies (somata) establishes lifelong latent infection in ganglionic neurons. We have previously reported that gK binds gB and is required for gB-mediated membrane fusion (Jambunatathan et al., J. Virol. 85:12910-12918, 2011; V. N. Chouljenko, A. V. Iyer, S. Chowdhury, J. Kim, and K. G. Kousoulas, J. Virol. 84:8596-8606, 2010). In the current study, we constructed a recombinant virus with the gK gene deleted in the highly virulent ocular HSV-1 strain McKrae. This recombinant virus failed to infect rat ganglionic neuronal axons alone or cocultured with Vero cells in microfluidic chambers. In addition, lack of gK expression prevented anterograde transmission of virions. These results suggest that gK is a critical determinant for neuronal infection and transmission.

Axones/virología , Herpes Simple/virología , Herpesvirus Humano 1/fisiología , Proteínas Virales/genética , Proteínas Virales/metabolismo , Liberación del Virus , Animales , Chlorocebus aethiops , Femenino , Técnicas de Inactivación de Genes , Herpesvirus Humano 1/genética , Humanos , Mutación , Neuronas/virología , Ratas , Ratas Sprague-Dawley , Células Vero
Cytometry A ; 81(3): 188-97, 2012 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-22290727


Proper illumination is essential for light microscopy. Whereas in early years incandescent light was the only illumination, today, more and more specialized light sources, such as lasers or arc lamps are used. Because of the high efficiency and brightness that light-emitting diodes (LED) have reached today, they have become a serious alternative for almost all kinds of illumination in light microscopy. LED have a high durability, do not need expensive electronics, and they can be switched in nanoseconds. Besides this, they are available throughout the UV/Vis/NIR-spectrum with a narrow bandwidth. This makes them ideal light sources for fluorescence microscopy. The white LED, with a color temperature ranging from 2,600 up to 5,000 K is an excellent choice for bright-field illumination with the additional advantage of simple brightness adjustments without changing the spectrum. This review discusses the different LED types, their use in the fluorescence microscope, and discusses LED as specialized illumination sources for Förster resonance energy transfer and fluorescent lifetime imaging microscopy.

Transferencia Resonante de Energía de Fluorescencia/instrumentación , Iluminación/instrumentación , Microscopía Confocal/instrumentación , Microscopía Fluorescente/instrumentación , Diseño de Equipo , Luz
Adv Health Sci Educ Theory Pract ; 17(5): 779-90, 2012 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-22037989


Using contemporary literary sources, we explore the powerful ideological framework that normalises prescription dependency as part of everyday life, focusing upon the treatment of mood disorders. Through a literary critical methodology, we read novels by American hyperrealists such as Bret Easton Ellis, David Foster Wallace and Rick Moody as symptomatic of prescription culture. Though we argue that these writers brilliantly understand the dangers of mood medication, they do not escape its logic, rather, 'writing it out' as they write against it. Indeed, we propose that their novels bear ironic similarities to medical texts such as the British National Formulary, usually seen as a neutral handbook for physicians' guidance in prescribing. We explicate their method as that of deconstruction, which, in contrast to more obvious critiques of chemical treatment, such as therapy, neither analyses nor cures. Though this method underplays the possibility of pragmatic and political resistance exemplified by alternative formularies such as the long-established feminist health manual Our Bodies, Ourselves, we argue that its very ambiguity uniquely exposes the complex determinisms associated with prescribed medication. We thus propose the value of drawing on deconstructive literature to better understand 'health' interventions such as prescription drugs for the regulation of mood.

Drama , Prescripciones de Medicamentos , Emociones/efectos de los fármacos , Medicina en la Literatura , Trastornos del Humor/tratamiento farmacológico , Femenino , Humanos , Masculino , Trastornos Relacionados con Sustancias
Psicol. USP ; 21(3): 513-530, jul.-set. 2010.
Artículo en Portugués | LILACS | ID: lil-569323


A autora discute o conceito de sublimação sob a luz da segunda teoria freudiana do conflito pulsional, a fim de examinar os aspectos funcionais e disfuncionais na criação literária, tomando como exemplo o caso de alguns escritores suicidas para destacar, dentre eles, o autor americano David Foster Wallace

The author discusses the concept of sublimation in view of Freud's second theory of drive conflict, exemplified in the cases of various suicidal writers, including David Foster Wallace, for the purpose of examining the functional and dysfunctional aspects of sublimation in the creation of literature

L'auteur discute le concept de sublimation sous la lumière de la deuxiémme théorie freudiènne du conflit pulsionale, tout en examinent les aspects functionaux et disfunctionaux de la création littéraire. Ils sont pris des exemples de quelques écrivains suicides, pour détacher l'oeuvre de l'auteur américain David Foster Wallace

La autora discute sobre el concepto de sublimación bajo la luz de la segunda teoria freudiana del conflicto pulsional, afin de examinar los aspectos funcionales y disfuncionales en la creación literaria. Ella toma, como ejemplo, el caso de algunos escritores suicidas para destacar, entre ellos, el autor Americano David Foster Wallace

Humanos , Conflicto Psicológico , Teoría Freudiana , Literatura , Sublimación Psicológica , Suicidio/psicología
Psicol. USP ; 21(3): 513-530, jul.-set. 2010.
Artículo en Portugués | Index Psicología - Revistas | ID: psi-46575


A autora discute o conceito de sublimação sob a luz da segunda teoria freudiana do conflito pulsional, a fim de examinar os aspectos funcionais e disfuncionais na criação literária, tomando como exemplo o caso de alguns escritores suicidas para destacar, dentre eles, o autor americano David Foster Wallace(AU)

The author discusses the concept of sublimation in view of Freud's second theory of drive conflict, exemplified in the cases of various suicidal writers, including David Foster Wallace, for the purpose of examining the functional and dysfunctional aspects of sublimation in the creation of literature(AU)

L'auteur discute le concept de sublimation sous la lumière de la deuxiémme théorie freudiènne du conflit pulsionale, tout en examinent les aspects functionaux et disfunctionaux de la création littéraire. Ils sont pris des exemples de quelques écrivains suicides, pour détacher l'oeuvre de l'auteur américain David Foster Wallace(AU)

La autora discute sobre el concepto de sublimación bajo la luz de la segunda teoria freudiana del conflicto pulsional, afin de examinar los aspectos funcionales y disfuncionales en la creación literaria. Ella toma, como ejemplo, el caso de algunos escritores suicidas para destacar, entre ellos, el autor Americano David Foster Wallace(AU)

Humanos , Sublimación Psicológica , Conflicto Psicológico , Suicidio/psicología , Teoría Freudiana , Literatura
Isis ; 100(2): 263-91, 2009 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-19653490


Konrad Lorenz's popularity in the United States has to be understood in the context of social concern about the mother-infant dyad after World War II. Child analysts David Levy, René Spitz, Margarethe Ribble, Therese Benedek, and John Bowlby argued that many psychopathologies were caused by a disruption in the mother-infant bond. Lorenz extended his work on imprinting to humans and argued that maternal care was also instinctual. The conjunction of psychoanalysis and ethology helped shore up the view that the mother-child dyad rests on an instinctual basis and is the cradle of personality formation. Amidst the Cold War emphasis on rebuilding an emotionally sound society, these views received widespread attention. Thus Lorenz built on the social relevance of psychoanalysis, while analysts gained legitimacy by drawing on the scientific authority of biology. Lorenz's work was central in a rising discourse that blamed the mother for emotional degeneration and helped him recast his eugenic fears in a socially acceptable way.

Conducta Animal , Patos , Etología/historia , Impronta Psicológica , Relaciones Padres-Hijo , Síntomas Afectivos/historia , Animales , Emociones , Padre , Historia del Siglo XX , Humanos , Modelos Animales , Madres , Responsabilidad Parental/historia , Psicoanálisis/historia , Psicología Infantil/historia
BMC Genomics ; 10 Suppl 1: I1, 2009 Jul 07.
Artículo en Inglés | MEDLINE | ID: mdl-19594867


The advent of high-throughput next generation sequencing technologies have fostered enormous potential applications of supercomputing techniques in genome sequencing, epi-genetics, metagenomics, personalized medicine, discovery of non-coding RNAs and protein-binding sites. To this end, the 2008 International Conference on Bioinformatics and Computational Biology (Biocomp) - 2008 World Congress on Computer Science, Computer Engineering and Applied Computing (Worldcomp) was designed to promote synergistic inter/multidisciplinary research and education in response to the current research trends and advances. The conference attracted more than two thousand scientists, medical doctors, engineers, professors and students gathered at Las Vegas, Nevada, USA during July 14-17 and received great success. Supported by International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design (IJCBDD), International Journal of Functional Informatics and Personalized Medicine (IJFIPM) and the leading research laboratories from Harvard, M.I.T., Purdue, UIUC, UCLA, Georgia Tech, UT Austin, U. of Minnesota, U. of Iowa etc, the conference received thousands of research papers. Each submitted paper was reviewed by at least three reviewers and accepted papers were required to satisfy reviewers' comments. Finally, the review board and the committee decided to select only 19 high-quality research papers for inclusion in this supplement to BMC Genomics based on the peer reviews only. The conference committee was very grateful for the Plenary Keynote Lectures given by: Dr. Brian D. Athey (University of Michigan Medical School), Dr. Vladimir N. Uversky (Indiana University School of Medicine), Dr. David A. Patterson (Member of United States National Academy of Sciences and National Academy of Engineering, University of California at Berkeley) and Anousheh Ansari (Prodea Systems, Space Ambassador). The theme of the conference to promote synergistic research and education has been achieved successfully.

Biología Computacional/métodos , Biología Computacional/tendencias , Congresos como Asunto
Stud Health Technol Inform ; 143: 358-63, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19380961


We describe the eFOSTr PROJECT, which has involved the design, implementation and testing of a unique Internet-based Personal Health Record (PHR) to support the families of transplant children and their healthcare providers. There are many gaps in the way that information is stored for children undergoing or about to undergo transplants. This group of children presents the most challenging exercise in information support between geographic and institutionally separated medical teams. They are, however, supported by highly motivated parents and families in life-threatening circumstances. A PHR was designed that allows for secure data entry, data storage, and easy controlled data access by the children's guardians or parents. The record includes contact and team member names, and medical data such as growth charts, immunizations, allergies, medications, lab values and scanned or digitized medical reports. Families can record the progress of their child as they would with a paper binder and customize their child's record with a photograph gallery and Internet link section for personal and general interest. Extensive computer-based testing of the PHR is complete. The system is being evaluated to determine the extent to which it meets the information needs of families and health providers in differing situations across Canada. The effectiveness of the system as a means for providing continuity of information and education is also being assessed. To conduct these evaluations, new users are being interviewed and tracked in a qualitative longitudinal study. Characteristics of the needs of the transplant families known to the David Foster Foundation (DFF) in Canada are described so that comparisons can be made to other patient groups who could benefit from their own adapted and specialized PHRs.

Familia , Internet , Sistemas de Registros Médicos Computarizados , Trasplantes , Adolescente , Colombia Británica , Niño , Humanos , Entrevistas como Asunto , Estudios Longitudinales , Apoyo Social , Encuestas y Cuestionarios
Nurs Manag (Harrow) ; 15(9): 8-9, 2009 Feb 10.
Artículo en Inglés | MEDLINE | ID: mdl-27736443


ENGLAND'S NEW deputy chief nursing officer (CNO), David Foster, is on a mission to raise the quality and quantity of nursing research. Having taken up post in December, Dr Foster aims to oversee the creation of an academic training pathway that nurses will think is right for them.