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Chem Commun (Camb) ; 54(87): 12333-12336, 2018 Oct 30.
Artículo en Inglés | MEDLINE | ID: mdl-30320316


A bio-derived sustainable medium based on water extract of pomegranate ash (WEPA) has, for the first time, been developed for the homocoupling of aryl halides under palladium-assistance. Avoiding the requirement of an external base, ligand and π-acid, the use of the proposed renewable medium offers remarkable attributes like wide substrate scope, good to nearly quantitative yields of biphenyls with exceptional chemoselectivity and scale up viability.

J Orthop Surg (Hong Kong) ; 26(3): 2309499018806700, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30352524


BACKGROUND: This prospective clinical-radiological study was conducted to determine whether the dynamic mobility stress radiographs can predict the postoperative vertebral height restoration, kyphosis correction, and cement volume injected after vertebroplasty. METHODS: Patients included had the diagnosis of significant back pain caused by osteoporotic vertebral compression fracture secondary to trivial injury. All the patients underwent routine preoperative sitting lateral spine radiograph, supine stress lateral spine radiograph, and supine anteroposterior spine radiograph. The radiological parameters recorded were anterior vertebral height (AVH), middle vertebral height (MVH), posterior vertebral height (PVH), MVH level below, wedge endplate angle (WEPA), and regional kyphotic angle (RKA). The supine stress versus sitting difference (SSD) for all the above parameters were calculated. RESULTS: A total of 28 patients (4 males; 24 females) with the mean age of 75.6 ± 7.7 years were recruited into this study. The mean cement volume injected was 5.5 ± 1.8 ml. There was no difference between supine stress and postoperative radiographs for AVH ( p = 0.507), PVH ( p = 0.913) and WEPA ( p = 0.379). The MVH ( p = 0.026) and RKA ( p = 0.005) were significantly less in the supine stress radiographs compared to postoperative radiographs. There was significant correlation ( p < 0.05) between supine stress and postoperative AVH, MVH, PVH, WEPA, and RKA. The SSD for AVH, PVH, WEPA, and RKA did not have significant correlation with the cement volume ( p > 0.05). Only the SSD-MVH had significant correlation with cement volume, but the correlation was weak ( r = 0.39, p = 0.04). CONCLUSIONS: Dynamic mobility stress radiographs can predict the postoperative vertebral height restoration and kyphosis correction after vertebroplasty for thoracolumbar osteoporotic fracture with intravertebral clefts. However, it did not reliably predict the amount of cement volume injected as it was affected by other factors.

Cementos para Huesos , Cifosis/diagnóstico , Vértebras Lumbares/lesiones , Fracturas Osteoporóticas/diagnóstico , Fracturas de la Columna Vertebral/diagnóstico , Vértebras Torácicas/lesiones , Vertebroplastia/métodos , Anciano , Anciano de 80 o más Años , Femenino , Fracturas por Compresión/diagnóstico , Fracturas por Compresión/cirugía , Humanos , Inyecciones , Cifosis/cirugía , Vértebras Lumbares/diagnóstico por imagen , Vértebras Lumbares/cirugía , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Fracturas Osteoporóticas/cirugía , Periodo Posoperatorio , Estudios Prospectivos , Rango del Movimiento Articular/fisiología , Fracturas de la Columna Vertebral/cirugía , Vértebras Torácicas/diagnóstico por imagen , Vértebras Torácicas/cirugía , Tomografía Computarizada por Rayos X
Zhongguo Zhong Yao Za Zhi ; 17(2): 107-10, 128, 1992 Feb.
Artículo en Chino | MEDLINE | ID: mdl-1418524


It was demonstrated that the water extract of Pilose Antler (WEPA) showed a higher inhibitory effect on MAO-B activities in the liver and brain tissues of aged mice, but nearly no effect on NAO-A. WEPA could significantly increase the contents of 5-HT, NE and DA in the brain tissues of aged mice. In vitro experiments revealed that the inhibition of WEPA on MAO-B was competitive, but on MAO-A was of mixed-type.

Cuernos de Venado , Ciervos , Materia Medica/farmacología , Inhibidores de la Monoaminooxidasa/farmacología , Monoaminooxidasa/metabolismo , Envejecimiento/efectos de los fármacos , Animales , Encéfalo/enzimología , Encéfalo/metabolismo , Dopamina/metabolismo , Femenino , Hígado/metabolismo , Masculino , Ratones , Norepinefrina/metabolismo , Serotonina/metabolismo