Recombinant, chimaeric live, attenuated vaccine (ChimeriVax) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates.

Monath, T P; Soike, K; Levenbook, I; Zhang, Z X; Arroyo, J; Delagrave, S; Myers, G; Barrett, A D; Shope, R E; Ratterree, M; Chambers, T J; Guirakhoo, F

Monath, T P; Soike, K; Levenbook, I; Zhang, Z X; Arroyo, J; Delagrave, S; Myers, G; Barrett, A D; Shope, R E; Ratterree, M; Chambers, T J; Guirakhoo, F.

Affiliation

Monath TP; OraVax Inc., Cambridge, MA 02139, USA. tmonath@oravax.com

Vaccine ; 17(15-16): 1869-82, 1999 Apr 09.

Article in En | MEDLINE | ID: mdl-10217584

Subject(s)

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Yellow fever virus / Viral Vaccines / Vaccines, Synthetic / Viral Nonstructural Proteins / Encephalitis, Japanese / Encephalitis Virus, Japanese Type of study: Prognostic_studies Limits: Animals Language: En Journal: Vaccine Year: 1999 Document type: Article Affiliation country:

Search on Google

Add to My VHL

XML

PubMed Links