Effects of leisure-time physical activity and ventilatory function on risk for stroke in men: the Reykjavík Study.
Ann Intern Med
; 130(12): 987-90, 1999 Jun 15.
Article
in En
| MEDLINE
| ID: mdl-10383369
ABSTRACT
BACKGROUND:
Stroke is a major cause of illness, death, and health expenditures. Leisure-time physical activity may reduce the risk for stroke.OBJECTIVE:
To examine the association of leisure-time physical activity and pulmonary function with risk for stroke.DESIGN:
Prospective cohort study.SETTING:
Reykjavík, Iceland.PARTICIPANTS:
4484 men 45 to 80 years of age followed for a mean (+/-SD) of 10.6 +/- 3.6 years. MEASUREMENTS Patients underwent physical examination, blood sampling, and spirometry and completed a questionnaire about health and exercise. Computerized hospital records were used to identify strokes, and the Icelandic National Registry was used to identify deaths.RESULTS:
New stroke developed in 249 men (5.6%) (hemorrhagic stroke in 44 [18%] and ischemic stroke in 205 [82%]). In a multivariable hazard analysis that controlled for known risk factors for cerebrovascular disease, leisure-time physical activity maintained after 40 years of age was associated with a reduced risk for stroke (relative risk, 0.69 [CI, 0.47 to 1.01] for total stroke and 0.62 [CI, 0.40 to 0.97] for ischemic stroke). Risk for stroke increased with diminished ventilatory function (FVC or FEV1) (relative risk, 1.9 [CI, 1.06 to 3.25] for the lowest compared with the highest quintile).CONCLUSION:
Middle-aged men who participate in leisure-time physical activity and have good pulmonary function seem to have a lower risk for stroke than men who are not active or have diminished pulmonary function.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cerebrovascular Disorders
/
Leisure Activities
/
Lung
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ann Intern Med
Year:
1999
Document type:
Article