New pyrrole derivatives as antimycobacterial agents analogs of BM212.
Bioorg Med Chem Lett
; 9(20): 2983-8, 1999 Oct 18.
Article
in En
| MEDLINE
| ID: mdl-10571160
ABSTRACT
During the course of our investigations in the field of azole antimicrobial agents, we have identified BM212 a pyrrole derivative with good in vitro activity against mycobacteria and candidae. These findings prompted us to prepare new pyrrole derivatives 2-6 in the hope of increasing the activity. The microbiological data showed interesting in vitro activity against Mycobacterium tuberculosis and atypical mycobacteria.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Piperazines
/
Pyrroles
/
Antitubercular Agents
Type of study:
Prognostic_studies
Language:
En
Journal:
Bioorg Med Chem Lett
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
1999
Document type:
Article
Affiliation country: