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Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family.
Thomson, J R; Machado, R D; Pauciulo, M W; Morgan, N V; Humbert, M; Elliott, G C; Ward, K; Yacoub, M; Mikhail, G; Rogers, P; Newman, J; Wheeler, L; Higenbottam, T; Gibbs, J S; Egan, J; Crozier, A; Peacock, A; Allcock, R; Corris, P; Loyd, J E; Trembath, R C; Nichols, W C.
Affiliation
  • Thomson JR; Division of Medical Genetics, Departments of Medicine and Genetics, University of Leicester, UK.
J Med Genet ; 37(10): 741-5, 2000 Oct.
Article in En | MEDLINE | ID: mdl-11015450
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multigene Family / Protein Serine-Threonine Kinases / Receptors, Transforming Growth Factor beta / Germ-Line Mutation / Hypertension, Pulmonary Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Language: En Journal: J Med Genet Year: 2000 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multigene Family / Protein Serine-Threonine Kinases / Receptors, Transforming Growth Factor beta / Germ-Line Mutation / Hypertension, Pulmonary Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Language: En Journal: J Med Genet Year: 2000 Document type: Article Affiliation country: Country of publication: