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Synthesis of louisianin C.
Beierle, John M; Osimboni, Ekundayo B; Metallinos, Costa; Zhao, Yajun; Kelly, T Ross.
Affiliation
  • Beierle JM; Department of Chemistry, Eugene F. Merkert Chemistry Center, Boston College, Chestnut Hill, MA 02467, USA.
J Org Chem ; 68(12): 4970-2, 2003 Jun 13.
Article in En | MEDLINE | ID: mdl-12790613
ABSTRACT
The synthesis of louisianin C (3), a member of a small family of 3,4,5-trisubstituted pyridyl natural products, is achieved in six steps and 11% overall yield starting from commercially available 3,5-dibromopyridine. The key step is a fluoride-induced desilylation-cyclization to afford carbinol 12.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Alkaloids / Allyl Compounds Language: En Journal: J Org Chem Year: 2003 Document type: Article Affiliation country:
Search on Google
Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Alkaloids / Allyl Compounds Language: En Journal: J Org Chem Year: 2003 Document type: Article Affiliation country:
...