Complete regression of primary gastric plasmacytoma following Helicobacter pylori eradication.
Ann Hematol
; 82(9): 589-92, 2003 Sep.
Article
in En
| MEDLINE
| ID: mdl-12898183
ABSTRACT
We describe the first case of a primary gastric plasmacytoma stage I completely regressed following Helicobacter pylori (H.pylori) eradication. The patient, a 61-year-old man, had a long history of chronic gastritis and gastric ulcers with recurrent gastrointestinal hemorrhage. Diagnosis of H.pylori infection was based on the positive urease breath test, the elevated titers of serum anti- H.pylori antibodies, and the detection of the bacterium in gastric mucosa biopsy specimens. Diagnosis of gastric plasmacytoma was based on the findings of histopathology, immunocytochemistry and in situ hybridization. Eradication of H.pylori with antibiotics was followed by disappearance of endoscopic and histopathologic features of the gastric tumor 3 months after the completion of the treatment. No relapse has been documented 20 months after the initial diagnosis of plasmacytoma. A possible causal relationship between the tumor and the underlying H.pylori infection is discussed.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plasmacytoma
/
Stomach Neoplasms
/
Helicobacter pylori
/
Helicobacter Infections
Type of study:
Diagnostic_studies
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ann Hematol
Journal subject:
HEMATOLOGIA
Year:
2003
Document type:
Article
Affiliation country: