Procedure for monitoring exposure to sulfur mustard based on modified edman degradation of globin.
J Anal Toxicol
; 28(5): 311-5, 2004.
Article
in En
| MEDLINE
| ID: mdl-15239848
ABSTRACT
A procedure for the modified Edman degradation of globin for determination of sulfur mustard adducts to the N-terminal valine residue in human hemoglobin has been developed for use under field laboratory conditions. The minimum detectable exposure level of human blood (in vitro) to sulfur mustard using this procedure is 100 nM. The interindividual and intraindividual variabilities of the procedure were acceptable (standard deviation < 10% and < 20%, respectively). The procedure could be properly set up and carried out in another laboratory within one working day, demonstrating its robustness.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hemoglobins
/
Chemical Warfare Agents
/
Environmental Monitoring
/
Mustard Gas
Limits:
Humans
Language:
En
Journal:
J Anal Toxicol
Year:
2004
Document type:
Article
Affiliation country: