[Influence of single leaf Asarum himalaicum on renal function of rabbits].
Zhong Xi Yi Jie He Xue Bao
; 2(3): 199-202, 2004 May.
Article
in Zh
| MEDLINE
| ID: mdl-15339444
ABSTRACT
OBJECTIVE:
To study the influence of single leaf Asarum himalaicum on the renal function of rabbits.METHODS:
Rabbits were divided into three groups. Asarum himalaicum, Asarum heterotropoides and normal saline were intravenously administered to the rabbits of one group respectively. The urine volume per minute, urine pH, urine glucose, protein and red blood cells, BUN, SCr, TXB2, 6-keto-PGF1alpha, TXB2/6-keto-PGF1alpha, endothelin, p-aminohippuric acid clearance rate and phenolsulfonphthalein excretion rate were tested before and after the administration.RESULTS:
A certain dosage of single leaf Asarum himalaicum caused acute renal failure in rabbits. The indices tested were significantly different between rabbits administered Asarum himalaicum and normal saline. As compared with the rabbits administered Asarum heterotropoides, the results of indices tested decreased, but without statistical significance, except for SCr.CONCLUSION:
The single leaf Asarum himalaicum can cause renal damage to rabbits. Its renal toxicity is lower that that of Asarum heterotropoides.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plant Leaves
/
Asarum
/
Plant Preparations
/
Kidney
Limits:
Animals
Language:
Zh
Journal:
Zhong Xi Yi Jie He Xue Bao
Journal subject:
MEDICINA
/
TERAPIAS COMPLEMENTARES
Year:
2004
Document type:
Article
Affiliation country: