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Full-term gestation and transvaginal delivery after wide resection of an abdominal desmoid tumor during pregnancy.
Durkin, Alan J; Korkolis, Dimitris P; Al-Saif, Osama; Zervos, Emmanuel E.
Affiliation
  • Durkin AJ; Department of Surgery, University of South Florida College of Medicine, Tampa General Hospital, Digestive Disorders Center, Tampa, Florida 33601, USA.
J Surg Oncol ; 89(2): 86-90, 2005 Feb 01.
Article in En | MEDLINE | ID: mdl-15660370
A 29-year-old female was diagnosed with a symptomatic, extra-abdominal desmoid tumor during the first trimester of pregnancy. Computerized tomography (CT) and transabdominal ultrasound (US) noted a mass within the left rectus sheath measuring up to 15 cm in greatest diameter, with mild compression of the uterus. Preoperative diagnosis was confirmed by core-needle biopsy of the lesion. At 20-weeks gestation, wide local resection of the tumor with disease-free margins, as well as abdominal wall reconstruction with polytetrafluoroethylene (PTFE) mesh was successfully undertaken. Histological examination of the tumor ex vivo confirmed that the lesion was a desmoid tumor consisting of spindle cells with dense infiltrating collagenous fibers. Subsequent to her resection, the patient completed a full-term pregnancy without complication, and proceeded with a complication-free transvaginal delivery at 39 weeks. This case illustrates the probable contribution of estrogens towards desmoid tumor development, the durability of abdominal wall reconstruction when subjected to the extraordinary strain of both a gravid uterus and labor, as well as the safety and efficacy of aggressive surgical therapy during pregnancy.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Pregnancy Complications, Neoplastic / Fibromatosis, Abdominal / Abdominal Wall / Delivery, Obstetric Limits: Adult / Female / Humans / Pregnancy Language: En Journal: J Surg Oncol Year: 2005 Document type: Article Affiliation country: Country of publication:
Search on Google
Collection: 01-internacional Database: MEDLINE Main subject: Pregnancy Complications, Neoplastic / Fibromatosis, Abdominal / Abdominal Wall / Delivery, Obstetric Limits: Adult / Female / Humans / Pregnancy Language: En Journal: J Surg Oncol Year: 2005 Document type: Article Affiliation country: Country of publication: