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Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport.
Hirth, Bradford H; Qiao, Shuang; Cuff, Lisa M; Cochran, Brian M; Pregel, Marko J; Gregory, Jill S; Sneddon, Scott F; Kane, John L.
Affiliation
  • Hirth BH; Genzyme Drug Discovery and Development, Genzyme Corp., One Kendall Sq., Cambridge, MA 02139, USA. bradford.hirth@genzyme.com <bradford.hirth@genzyme.com>
Bioorg Med Chem Lett ; 15(8): 2087-91, 2005 Apr 15.
Article in En | MEDLINE | ID: mdl-15808474
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Collection: 01-internacional Database: MEDLINE Main subject: Chlorides / Cystic Fibrosis Transmembrane Conductance Regulator / Tetrahydroisoquinolines / Amides Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2005 Document type: Article
Search on Google
Add to My VHL
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Chlorides / Cystic Fibrosis Transmembrane Conductance Regulator / Tetrahydroisoquinolines / Amides Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2005 Document type: Article