Flow-injection determination of streptomycin residues in milk using the luminol-periodate-Mn2+ chemiluminescence system.
Luminescence
; 21(1): 36-42, 2006.
Article
in En
| MEDLINE
| ID: mdl-16100747
A novel flow-injection method with chemiluminescence detection was developed for the determination of streptomycin residues in milk, based on the enhancement by streptomycin of the luminol-potassium periodate-Mn(2+) chemiluminescence system. The assay allowed analysis of streptomycin residues in whole milk samples ( approximately 3.5% fat) after sample work-up procedures. The limit of detection was 5.16 x 10(-9) mol/L for milk, and was far below the regulations of maximum residue limits (MRLs). The relative standard deviation (RSD) for 8.66 x 10(-8) mol/L streptomycin was 1.94% (n = 15) in milk. The results obtained for the assay of streptomycin residues in milk was comparable with those obtained by the official methods (ELISA) and demonstrated good accuracy and precision. The possible mechanism is briefly discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Drug Residues
/
Streptomycin
/
Flow Injection Analysis
/
Periodic Acid
/
Milk
/
Luminol
/
Manganese
/
Anti-Bacterial Agents
Limits:
Animals
Language:
En
Journal:
Luminescence
Journal subject:
BIOFISICA
/
BIOQUIMICA
Year:
2006
Document type:
Article
Country of publication: