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Clinical significance of development of Philadelphia-chromosome negative clones in patients with chronic myeloid leukemia treated with imatinib mesylate.
Perel, J M; McCarthy, C; Walker, O; Irving, I; Williams, B; Kennedy, G A.
Affiliation
  • Perel JM; Queensland Health Pathology Service, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.
Haematologica ; 90 Suppl: ECR25, 2005 Nov.
Article in En | MEDLINE | ID: mdl-16266916
Subject(s)
Antineoplastic Agents/therapeutic use; Clone Cells/ultrastructure; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy; Leukemia, Myeloid, Chronic-Phase/drug therapy; Leukemia, Myeloid/genetics; Neoplastic Stem Cells/drug effects; Philadelphia Chromosome; Piperazines/therapeutic use; Protein Kinase Inhibitors/therapeutic use; Pyrimidines/therapeutic use; Acute Disease; Aged; Antineoplastic Agents/pharmacology; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Benzamides; Bone Marrow/pathology; Cytarabine/administration & dosage; Disease Progression; Fatal Outcome; Fusion Proteins, bcr-abl/antagonists & inhibitors; Fusion Proteins, bcr-abl/genetics; Granulocyte Colony-Stimulating Factor/administration & dosage; Humans; Hydroxyurea/administration & dosage; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Interferons/administration & dosage; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/enzymology; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology; Leukemia, Myeloid/pathology; Leukemia, Myeloid, Chronic-Phase/enzymology; Leukemia, Myeloid, Chronic-Phase/genetics; Leukemia, Myeloid, Chronic-Phase/pathology; Male; Middle Aged; Neoplastic Stem Cells/enzymology; Piperazines/pharmacology; Protein Kinase Inhibitors/pharmacology; Pyrimidines/pharmacology; Selection, Genetic; Vidarabine/administration & dosage; Vidarabine/analogs & derivatives
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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyrimidines / Neoplastic Stem Cells / Philadelphia Chromosome / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Leukemia, Myeloid, Chronic-Phase / Leukemia, Myeloid / Clone Cells / Protein Kinase Inhibitors / Antineoplastic Agents Language: En Journal: Haematologica Year: 2005 Document type: Article Affiliation country:
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyrimidines / Neoplastic Stem Cells / Philadelphia Chromosome / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Leukemia, Myeloid, Chronic-Phase / Leukemia, Myeloid / Clone Cells / Protein Kinase Inhibitors / Antineoplastic Agents Language: En Journal: Haematologica Year: 2005 Document type: Article Affiliation country: