Unusual entry to the novel 8-halo-N1-ribosyl hypoxanthine system by degradation of a cyclic adenosine-5'-diphosphate ribose analogue.
Chem Commun (Camb)
; (10): 1127-9, 2006 Mar 14.
Article
in En
| MEDLINE
| ID: mdl-16514461
ABSTRACT
Cyclic 8-bromo-inosine-5'-diphosphate ribose (8-Br-N1-cIDPR) was cleanly degraded at acidic pH by N9 ribosyl scission and subsequent pyrophosphate cleavage to give 8-bromo-N1-ribosyl hypoxanthine 5'-monophosphate (8-Br-N1-IMP), a novel class of mononucleotide, as the sole product.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phosphates
/
Hypoxanthine
/
Cyclic ADP-Ribose
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2006
Document type:
Article