Using STN DBS and medication reduction as a strategy to treat pathological gambling in Parkinson's disease.
Parkinsonism Relat Disord
; 13(6): 369-71, 2007 Aug.
Article
in En
| MEDLINE
| ID: mdl-17049455
ABSTRACT
We describe two patients with Parkinson's disease (PD) who developed clinical criteria of pathological gambling addiction in the setting of increased dopamine replacement therapy (levodopa and dopamine agonist medications). The second patient showed also signs of dopamine dysregulation syndrome, with an addiction to dopaminergic medication. Neither patients responded to the standard therapy for gambling behavior, but dramatically improved after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) and early postoperative withdrawal of dopaminergic therapy. The possible therapeutic role of subthalamic nucleus deep brain stimulation (STN-DBS) on such a disabling behavior needs to be investigated prospectively.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parkinson Disease
/
Dopamine Agonists
/
Subthalamic Nucleus
/
Deep Brain Stimulation
/
Benzothiazoles
/
Gambling
Limits:
Adult
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Parkinsonism Relat Disord
Journal subject:
NEUROLOGIA
Year:
2007
Document type:
Article
Affiliation country: