Wound epidermis formation and function in urodele amphibian limb regeneration.
Cell Mol Life Sci
; 65(1): 73-9, 2008 Jan.
Article
in En
| MEDLINE
| ID: mdl-18030417
ABSTRACT
Upon amputation of the urodele limb, the epidermal cells surrounding the amputation plane migrate to heal the wound. The resulting wound epidermis (WE) induces the regeneration process, resulting in blastema formation, cell division, and ultimately repatterning into a new limb. Despite its central role in the initiation of limb regeneration, little is known about how the WE forms. Here we discuss various models of WE formation and the experimental data in support of each.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Regeneration
/
Epidermis
/
Extremities
Limits:
Animals
Language:
En
Journal:
Cell Mol Life Sci
Journal subject:
BIOLOGIA MOLECULAR
Year:
2008
Document type:
Article
Affiliation country: