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Asymmetric synthesis and receptor pharmacology of the group II mGlu receptor ligand (1S,2R,3R,5R,6S)-2-amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid-HYDIA.
Woltering, Thomas J; Adam, Geo; Huguenin, Philipp; Wichmann, Jürgen; Kolczewski, Sabine; Gatti, Silvia; Bourson, Anne; Kew, James N C; Richards, Grayson; Kemp, John A; Mutel, Vincent; Knoflach, Frédéric.
Affiliation
  • Woltering TJ; Pharmaceuticals Division, Discovery Chemistry and Pharma Research, F. Hoffmann-La Roche AG, 4070 Basel, Switzerland. thomas.woltering@roche.com
ChemMedChem ; 3(2): 323-35, 2008 Feb.
Article in En | MEDLINE | ID: mdl-18058780
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Collection: 01-internacional Database: MEDLINE Main subject: Bridged Bicyclo Compounds / Receptors, Metabotropic Glutamate / Excitatory Amino Acid Agonists Limits: Animals Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2008 Document type: Article Affiliation country: Country of publication:
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Bridged Bicyclo Compounds / Receptors, Metabotropic Glutamate / Excitatory Amino Acid Agonists Limits: Animals Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2008 Document type: Article Affiliation country: Country of publication: