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In vitro activity of telavancin against resistant gram-positive bacteria.
Krause, Kevin M; Renelli, Marika; Difuntorum, Stacey; Wu, Terry X; Debabov, Dmitri V; Benton, Bret M.
Affiliation
  • Krause KM; Theravance, Inc., South San Francisco, CA 94080, USA.
Antimicrob Agents Chemother ; 52(7): 2647-52, 2008 Jul.
Article in En | MEDLINE | ID: mdl-18443122
ABSTRACT
The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC(90), 0.5 to 1 microg/ml), streptococci (all MICs, < or =0.12 microg/ml), and VanB-type enterococci (all MICs, < or =2 microg/ml). Time-kill studies demonstrated the potent bactericidal activity of telavancin.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gram-Positive Bacteria / Aminoglycosides / Anti-Bacterial Agents Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2008 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gram-Positive Bacteria / Aminoglycosides / Anti-Bacterial Agents Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2008 Document type: Article Affiliation country: