Effects of a challenge dose of Salmonella Typhimurium or Salmonella Yoruba on the patterns of excretion and antibody responses of pigs.
Vet Rec
; 162(18): 580-6, 2008 May 03.
Article
in En
| MEDLINE
| ID: mdl-18453377
ABSTRACT
The epidemiology of a feed-associated Salmonella serotype (Salmonella Yoruba) was compared with that of a 'classical' serotype (Salmonella Typhimurium) by inoculating pigs aged 10 weeks with 0.65 x 10(3), 0.65 x 10(6) or 0.65 x 10(9) colony-forming units (cfu) of either serotype. The pigs were then monitored for eight weeks with respect to the faecal excretion of Salmonella species and the presence of serum antibodies. Only minor differences were observed between the two serotypes but the dose inoculated had significant effects. The pigs inoculated with 0.65 x 10(9) cfu shed Salmonella species in faeces constantly for four weeks, and intermittently during the subsequent four weeks; the pigs inoculated with 0.65 x 10(6) cfu shed Salmonella species intermittently for four weeks, but not for longer, and the pigs inoculated with 0.65 x 10(3) cfu generally did not excrete Salmonella species. The pigs inoculated with 0.65 x 10(9) cfu S Typhimurium seroconverted at a high titre within two weeks, the pigs inoculated with 0.65 x 10(6) cfu seroconverted later and with lower titres of antibodies, and the pigs inoculated with 0.65 x 10(3) cfu did not seroconvert. A similar pattern was observed with S Yoruba, but the responses were slower and at lower titres.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Salmonella
/
Swine
/
Antibodies, Bacterial
Limits:
Animals
Country/Region as subject:
Europa
Language:
En
Journal:
Vet Rec
Year:
2008
Document type:
Article
Affiliation country: